The partnership combines UAB's expertise in engineering and medicine with VICIS's innovative helmet technology to reduce impact forces. The resulting helmets will better protect players' brains from concussions, a pressing concern in football.
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Researchers used fMRI to track brain activity in 75 concussion patients and found altered patterns associated with worse symptoms months later. The study identified abnormal connectivity in frontal areas and visual networks, suggesting a higher risk for long-term post-concussive symptoms.
A new study from the University of Tennessee Health Science Center found that advances in imaging technology have led to a six-fold increase in the diagnosis of blunt cerebrovascular injuries in trauma patients. This has resulted in a significant decline in stroke and related death rates over the past 30 years.
Researchers mapped premature infant brains using MRI scans to predict future disabilities. A greater volume of white matter injury was linked to movement and thinking problems at 18 months.
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A $2.7 million grant will fund research on veterans with traumatic brain injuries using a virtual technology platform to improve cognitive and functional deficits. The project aims to train strategies for complex real-life tasks, including money management and time planning.
A new study from Drexel University College of Medicine suggests that a commonly used antibiotic, minocycline, may exacerbate cognitive deficits in newborn rats with traumatic brain injury. The researchers hypothesize that the treatment, which targets inflammation, may be ineffective or even harmful to developing brains.
Researchers observed that brain cell powerhouses, called mitochondria, can quickly become dysfunctional after injury like stroke or trauma. However, they often resume their normal shape once blood and oxygen are restored, suggesting a potential new avenue for improving recovery from such injuries.
Research found that nearly 1,400 US servicemen sustained genitourinary (GU) injuries during the Iraq and Afghanistan wars. The majority of patients suffered severe testicular and/or penile injuries, often part of polytraumatic injuries. Novel treatments are needed to address long-term sexual and reproductive health concerns.
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Vision problems are commonly reported in children with concussions and are independently associated with academic difficulty. Blurred vision and difficulty concentrating are among the most common symptoms affecting academic performance in pediatric patients.
A Clemson University team, led by Gregory Batt and John DesJardins, is working on improving facemask designs to help reduce the severity of head injuries in football. They are using a linear drop tower system to test various facemask materials and structures.
Researchers at Northwestern University's Auditory Neuroscience Laboratory have discovered a biological marker in the auditory system that can reliably diagnose concussions. The study found that children who suffered concussions had a distinct pattern in their brain activity when exposed to sound, which could be used to identify them.
A new study shows that recovering from traumatic brain injury (TBI) and improving sleep quality occur in parallel. As patients regained consciousness, their sleep-wake cycles also improved.
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A study published in Journal of Psychiatric Research found that homeless adults with mental illness and a history of traumatic brain injury are more likely to experience adverse health conditions, increased use of emergency departments, and suicidal risk. The research highlights the need for specialized services such as clinical treatm...
A study by Children's National Hospital found that Sirt1 plays a crucial role in regenerating glial cells from endogenous progenitor cells after hypoxia-related brain injury. The protein's activity can be modulated by sirtinol, an off-the-shelf drug, and may help alleviate developmental delays in preterm infants.
A team of researchers at Colorado State University is investigating the use of a test developed to detect early-stage chronic wasting disease in deer to identify the onset of brain disorders, including concussion-related trauma, in humans. The test may also be used to detect misfolded proteins found in people with Alzheimer's, Parkinso...
A new study found that people with traumatic brain injury are approximately 2.5 times more likely to be incarcerated in a federal correctional facility in Canada than those without a history of TBI. The study, which included nearly 1.42 million adults aged 18-28, highlighted the association between TBI and incarceration rates.
Researchers at Johns Hopkins Medicine found evidence of brain injury and repair in young NFL players compared to a control group. PET imaging revealed higher levels of a biomarker associated with brain injury in eight of the 12 brain regions studied, suggesting a link between concussions and chronic traumatic encephalopathy (CTE).
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Researchers found disrupted brain circuitry in service members with mild traumatic brain injury (mTBI) who developed depression symptoms, linking physical foundation to emotional processing and rumination. This study may lead to personalized treatment strategies for future care.
Researchers found higher distribution volume in 8 brain regions among NFL players compared to nonplayers, suggesting localized brain injury may be associated with football play. Limited white matter changes were observed in the brains of NFL players.
A combination of methylphenidate and cognitive-behavioral rehabilitation has been shown to improve attention, episodic memory, working memory, and executive functioning in adults with traumatic brain injuries. The study compared the effectiveness of two forms of cognitive therapy with and without the use of methylphenidate.
A combined pharmacological therapy and rehabilitation program shows promise in treating persistent cognitive difficulties after traumatic brain injuries, with modest yet significant improvements noted in verbal and nonverbal learning abilities, working memory, and divided attention.
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Researchers found that ACL injuries alter brain activity related to leg movement, relying on visual systems instead of instinctive movement. This study suggests a new rehabilitation approach using strobe glasses to help patients rewire their brains and regain natural movement.
Researchers identify direct link between brain inflammation and CTE, with longer football careers predicting increased inflammation and disease progression. The study suggests that treating inflammation could prevent or lessen CTE development, offering potential biomarkers for early identification.
A recent study in mice suggests that protecting axons may prevent the development of neurological problems associated with TBI. The researchers used mice with a genetic mutation that protects axons and found that they did not develop vision or cognitive problems after blast-related TBI.
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A new system has been developed to better understand variables involved in survival from gunshot wounds to the head. The study found that level of consciousness upon arrival, pupillary reactivity, and injury severity score are key factors in determining survival rate.
Researchers developed a new tool called SPIN-Score to predict survival after gunshot wounds, using pupil response and motor tests as key predictors. The tool accurately predicted survival rates with an excellent accuracy of 96%, offering valuable insights for doctors and families making life-or-death decisions.
A recent study by the American Academy of Pediatrics found that nearly half of concussion patients were playing football when they sustained their injury, and 71 athletes returned to play on the same day. Patients who immediately returned to play reported less severe symptoms initially, but these symptoms worsened over time.
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Dr. Erica Weber at Kessler Foundation has received a $70,000 Merit Award to fund her research on strategies to improve prospective memory in individuals with traumatic brain injury (TBI). Her work aims to help people with TBI remember to perform tasks in the future using self-generation techniques.
Researchers at Women & Infants Hospital have received NIH grants to evaluate treatment strategies for perinatal brain injury. The studies aim to prevent or decrease brain damage in infants at risk for cerebral palsy and other developmental disabilities.
A $1.65 million Department of Defense grant will support the development of a brain-machine-brain interface (BMBI) aimed at helping TBI and stroke patients regain motor function. The BMBI records signals from one part of the brain, processes them in real time, then bridges the injury by stimulating a second part of the brain.
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Researchers at Barrow Neurological Institute have identified a link between domestic violence and traumatic brain injury, with 88% of victims suffering more than one head injury. The study aims to expand awareness and treatment options for domestic violence survivors, who often lack access to resources.
The Kessler Foundation has been awarded a $2.3 million Spinal Cord Injury Model System (SCIMS) grant to support the Northern New Jersey SCI System. The grant will enable research into pharmacologic approaches to managing bladder dysfunction and improve care for respiratory complications.
Researchers aim to develop a diagnostic test for glymphatic system impairment after traumatic brain injury, which can lead to cognitive difficulties. The study seeks to identify treatments that could help repair the system, with potential applications in military personnel and servicemen.
A systematic review of 10 international studies suggests that diffusion tensor imaging (DTI) may be an effective diagnostic tool for identifying and predicting the likelihood of post-concussion syndrome (PCS). DTI scans can detect micro abnormalities in the brain not picked up by routine imaging methods, potentially leading to earlier ...
Researchers developed an objective test to diagnose mild traumatic brain injury (mTBI) using the I-Portal goggle, achieving 95% specificity and 89% sensitivity. This technology has the potential to revolutionize concussion diagnosis and treatment in sports, leading to better outcomes for athletes.
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A study published in the New England Journal of Medicine found that craniectomy significantly reduces the risk of death from brain swelling after a head injury. Craniectomy also improved patient outcomes at 6-12 months post-injury, with nearly half of patients regaining independence.
Research shows that adults with moderate to severe traumatic brain injury (TBI) are twice as likely to die from an unintentional injury. Changes in cognition and balance increase the risk of subsequent injuries. A patient-centered assessment tool can help identify risks and prevent further injuries.
A study of over a million Swedes found that childhood brain injuries increased the chances of poor school attainment, psychiatric care, disability benefits, and premature death. Repeated mild or severe brain injuries were associated with even higher risks.
Researchers at UCLA have discovered that MRI scans can detect the shrinkage of key brain regions in individuals with cognitive problems, similar to those seen in CTE cases confirmed by autopsy. This finding raises the possibility of using MRI scans to diagnose CTE in living patients.
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A study found nearly 361,000 children under 5 were treated for stroller or carrier-related injuries between 1990 and 2010. Head and face injuries accounted for most cases, with traumatic brain injuries on the rise, particularly in carriers.
Scientists have developed a neuron-targeting nanoparticle that can deliver RNA to damaged brain cells, reducing the impact of chronic conditions like depression and memory problems after TBI. The treatment showed promise in an animal model, with 80% reduction in protein associated with neuronal cell death.
A new CDC study found that about 27% of patients with mild traumatic brain injury who returned for follow-up care were positive for post-traumatic stress disorder (PTSD). The study identified risk factors, including functional disability, psychiatric symptoms, and performance on measures of visual processing and mental flexibility.
Researchers found that inosine treatment led to improved motor control in four out of four treated monkeys, with three returning to their pre-operative grasping methods. The study suggests neural plasticity as a therapeutic target for recovering fine motor control and grasping ability after brain injury.
A new study found that starting blood-thinning medications within 72 hours of hospital arrival significantly reduces the likelihood of life-threatening blood clots in patients with traumatic brain injury. The study also showed no increase in risk of bleeding complications or death.
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Researchers at St. Michael's Hospital discovered brain shrinkage, reduced blood flow, and white matter damage in college athletes with a history of concussion. These findings suggest that even young, healthy adults may be affected by repeated head injuries.
A new probe allows for pinpoint brain temperature measurements in moving lab animals, precision measured to a fraction of a degree. The probe's small size enables spatially precise temperature readings from small brain areas, paving the way for real-time monitoring of brain temperature after traumatic brain injury or stroke.
Researchers investigated the effectiveness of neurorehabilitation treatments for individuals with brain injury or stroke, highlighting adaptable, measurable, and evidence-based therapies. Studies found that holistic neuropsychological rehabilitation can reduce reported symptoms and carer strain.
Research found no association between traumatic brain injury and dementia or Alzheimer disease, but increased risk of Parkinson's disease, progression of parkinsonism, and microinfarcts were observed. The study analyzed data from over 7,000 participants with a history of traumatic brain injury.
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Scientists developed a novel peptide that protects cognitive function after mild traumatic brain injury by reducing inflammation, cell death, and cognitive impairments in mice. The peptide, called TXM-peptide, mimics the antioxidant activity of thioredoxin and inhibits the inflammatory pathway.
Scientists at Sanford Burnham Prebys Medical Discovery Institute have discovered a peptide sequence that can carry molecules and nanoparticles to acutely damaged areas of the brain, providing a new means of delivering therapeutics for traumatic brain injuries. This technology has the potential to minimize the effects of secondary injur...
Despite medical community's understanding of brain function, the double-trauma amnesia cure belief persisted due to anecdotal evidence and flawed theories. A French scientist named Francois Xavier Bichat proposed the idea that a second blow could restore memories in the late 18th century, but his claims were not backed by specific cases.
Researchers used advanced MRI to predict which concussion patients would fully recover and identify brain areas involved in the repair process. The study found that high FA white-matter areas correlated with better outcomes, while low FA areas showed axon damage and cognitive impairment.
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Researchers found a distinctive pattern of injury in the brains of deceased military personnel who survived high explosive attacks, suggesting a link between blast exposure and neuropsychiatric symptoms. The study's findings highlight the need for further research to understand the underlying pathophysiology of traumatic brain injury.
A new study from CHOP and CDC found that 82% of concussions among 0-17 year olds were diagnosed at primary care sites, while only 12% were in the emergency department. Early diagnosis and treatment are crucial for concussion recovery, and targeted training can help primary care providers diagnose and treat most cases.
Researchers found that whole-brain energy turnover directly predicted current level of awareness and likelihood of recovery within a year. Brain metabolic activity above 42% threshold was associated with signs of awareness or recovered responsiveness.
Researchers have found that anemia can negatively impact patients with traumatic brain injuries, leading to poorer outcomes. For each increase in hemoglobin levels, the likelihood of a good outcome increased by 33 percent.
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A University of Washington study reveals significant barriers in accessing rehabilitation services for children with traumatic brain injuries from low-income households with limited English proficiency. The study found that less than 20% of providers accepted Medicaid and provided language interpretation, highlighting the need for incr...
A new study from the University of Rochester Medical Center suggests that student-athletes who experience concussions often struggle academically, even after returning to school. The research found significant academic problems among students with concussions compared to those with other sports-related injuries.
Researchers at SDSU used fruit flies to model traumatic brain injuries, finding damage to neurons and changes in sleep patterns. The study suggests that studying these genetic and cellular factors may reveal ways to improve the brain's resilience to injuries.
A USF professor is investigating the possibility that CTE can start when an on-field collision generates a 'seed' that spreads protein abnormality in the brain. Similar processes may be at work for Alzheimer's and Parkinson's diseases.