Articles tagged with Brain Injuries
Computational simulations help clinicians visualize AHT impact and predict short- and long-term effects. The study reveals CSF protection is limited to the first shake, with repeated shakes causing brain damage.
A first-in-human study of a drug candidate targeting brain inflammation has shown promising results, supporting its further development for treating acute brain injuries. The study, conducted by a team from the University of Kentucky and other institutions, found that MW189 was safe and well-tolerated in healthy volunteers.
Researchers at the University of Wisconsin-Madison have discovered a potential treatment approach for concussions by cooling brain cells to an optimal temperature. The study found that cooling cells to 33 degrees Celsius provided the most protective benefit after 24 and 48 hours post-injury.
A study in the Clinical Journal of Sport Medicine reports that most patients with sports-related mild traumatic brain injury (mTBI) do not achieve clinical recovery within two weeks after injury. Recovery times varied by age and presence of concussion modifiers, highlighting the importance of early access to care.
Researchers found that rejuvenating immune cells, specifically microglia, significantly improved brain repair and learning abilities in animal models. This discovery challenges the long-held assumption that microglia drive inflammation after brain injuries.
A Rutgers study found that middle school football players who wore padded helmets and used safe tackling and blocking techniques had no concussions during a 20-practice, seven-game season. The study's results suggest that the use of Guardian Caps and age of participants may have contributed to the low number of impacts recorded.
A UC Riverside-led study found that brains treated with certain drugs within days of an injury have a reduced risk of developing epilepsy later in life. The development of epilepsy is linked to an immune system receptor, TLR4, which increases excitability in the hippocampus.
A preclinical study suggests that targeting overactive immune cells in the brain can limit brain cell loss and reverse cognitive and motor difficulties caused by traumatic brain injury (TBI). Mice treated with an experimental drug recovered markedly better than control mice, showing less tissue loss and improved motor and cognitive per...
New preclinical research suggests that targeting overactive immune cells can improve traumatic brain injury recovery and modulate chronic neurotoxic effects. The study found that a therapeutic strategy to inhibit microglia cells after TBI led to better motor and cognitive performance in mice.
Research in mice finds that targeting overactive immune cells can improve TBI recovery, reducing inflammation and neurodegeneration. Quelling chronic inflammation may offer a new treatment option for long-term recovery from traumatic brain injuries.
A new study published in Cortex journal reveals that visual rehabilitation therapy improved vision in almost 80% of stroke and traumatic brain injury patients. The NeuroEyeCoach therapy was shown to improve daily activities, such as navigating surroundings, identifying obstacles, and avoiding collisions.
A new brain scan-blood test panel has been developed to help diagnose brain trauma following battlefield blasts. The panel combines functional assessment with blood tests and brain scans to estimate brain degeneration in human veterans exposed to IED blasts.
A new study at Children's Hospital Los Angeles uses advanced imaging techniques to optimize a leading-edge therapy for babies with hypoxic brain injuries. The results demonstrate effective cooling in the deep areas of the brain, which are most often damaged by lack of oxygen.
A study led by McGill University found that childhood behaviours identified by teachers, such as inattention-hyperactivity, predicted subsequent traumatic brain injuries in boys. The research suggests that treatments to reduce these behaviours may decrease the risk for TBIs.
Researchers have identified calcitonin gene-related peptide (CGRP) as a link between traumatic brain injuries and post-concussion headaches. A preclinical study found that administering an anti-CGRP treatment before or after injury significantly reduced pain responses and prevented reactivated headaches.
A team of doctors and engineers developed a noninvasive device that measures brain metabolism using an infrared laser, enabling faster and more certain concussion diagnoses. The technology could guide treatment for serious brain injuries and other conditions, improving patient outcomes.
A new UMass Amherst study found that military members with serious brain injuries are at a greater risk of experiencing mental health disorders, including PTSD, anxiety, and mood disorders. The research suggests that critically injured soldiers with severe TBI have particularly high rates of these conditions.
Researchers at Northwestern University discovered that injecting nanoparticles into the bloodstream can significantly reduce brain swelling and damage after a traumatic brain injury. The treatment may provide new hope for individuals with significant traumatic brain injuries, including young athletes and soldiers.
Researchers analyzed data from over 100 youth football players, finding that they are more susceptible to concussion at lower levels of acceleration than older athletes. The study's findings provide critical information for designing and testing protective equipment.
Researchers at the University of Texas Medical Branch have discovered that traumatic brain injuries can lead to a cascade of health issues, including fatigue, depression, and memory problems. Growth hormone replacement therapy has been shown to improve symptoms, but the mechanisms behind its effectiveness are still not fully understood.
A recent study found that community-dwellers with Alzheimer's disease who used antipsychotics had a 29% higher risk of head injuries and a 22% higher risk of traumatic brain injuries. The risk was highest when antipsychotics were first introduced.
Researchers at the University of Arizona have discovered that early morning blue light exposure therapy can aid in the healing process of people impacted by mild traumatic brain injuries. The study found that improved sleep quality led to improvements in cognitive function, reduced daytime sleepiness, and actual brain repair.
A new photoacoustic tomography technique aims to improve the detection and measurement of hypoxic-ischemic brain injuries in preterm newborns without sedation or radiation. The technology has the potential to revolutionize neonatal brain imaging management, enabling earlier treatment and improved outcomes for patients.
A nationwide Finnish study found that individuals with Alzheimer's disease who took antipsychotic medications had a 29% higher risk of head injuries compared to those who didn't. This is particularly concerning as these patients already have a higher risk of falling and traumatic brain injuries.
A new study found that road injury deaths have decreased worldwide, but the risk of death from a road accident remains high in some countries. In 2017, 54 million people were injured in road accidents, resulting in 1.2 million deaths globally.
A new study published in JAMA Neurology suggests that early clinical treatment for concussions can significantly reduce recovery time. Athletes who received treatment within the first week of their injury recovered faster than those who delayed care, with longer recovery times reported after eight days to three weeks post-injury.
A three-year study found concussions are twice as prevalent as previously believed and occur significantly more often off the playing field. The research also showed that females are more susceptible to concussions and that incidence is higher among non-sport-related activities, such as falls and motor vehicle accidents.
Researchers at the University of Georgia developed a new cell-to-cell messaging technology using bio-manufactured exosomes to treat traumatic brain injuries. The treatment, called IV treatment, showed improved functional recovery in rats after TBI.
A new study reveals that concussion damage affects the way information is transmitted between brain hemispheres. Researchers found a delay in reaction time when processing words presented to the left visual field, indicating a problem with information crossing from one hemisphere to another.
A new study published in The Lancet Public Health estimates that one in two homeless people experience a head injury, with moderate or severe injuries affecting nearly a quarter. The research suggests providing stable housing may lower the risk of traumatic brain injury for this vulnerable group.
Persistent concussion symptoms in children may be a sign of reduced brain function and decreased grey matter, according to researchers at the University of Queensland. The study found that poor sleep was linked to decreases in brain grey matter and reduced brain function, allowing for predictions of recovery outcomes with 86% accuracy.
Researchers at the University of Helsinki developed an artificial intelligence-based algorithm to improve intensive care for patients with severe traumatic brain injuries. The algorithm accurately predicts patient mortality within 30 days, showing promising results in a proof-of-concept study.
A new study from UBC's Okanagan campus aims to create better supports and outcomes for women survivors of intimate partner violence. The research found that many women experience traumatic brain injuries, with chronic symptoms including headaches, dizziness, and difficulty remembering.
Researchers at the University of California, Irvine developed a cell therapy that transplants inhibitory neurons to improve memory precision after traumatic brain injury. The treatment prevented seizures in mice with traumatic brain injuries, showing promising results for potential human treatment.
A study found associations between default mode network connectivity and emotion recognition and social integration in individuals with moderate to severe brain injury. Increased prefrontal-temporal connectivity predicted participants' level of social integration, underscoring the importance of brain connectivity metrics in TBI recovery.
Researchers at UCLA have discovered that a traumatic brain injury causes changes in the amygdala, leading to increased fear responses and PTSD symptoms. The study found that rats with brain injuries exhibited abnormal neural activity in the amygdala and thalamus, suggesting potential new targets for treating PTSD.
A Rutgers study found that cycling-related facial and head injuries have remained steady despite an increase in bicyclists on the road. However, there was a significant rise in serious injuries among older adults, particularly those aged 55-64, with over 86,000 hospitalizations from 2008 to 2017.
The Penn Medicine team will analyze clinical data from traumatic brain injury (TBI) and age-related dementias to understand the mechanisms of TReND, a umbrella term for progressive neuropathologies after TBI. The study aims to establish diagnostic criteria for Chronic Traumatic Encephalopathy and other forms of TReND.
A recent study published in The BMJ found that transferring extremely premature babies from lower to higher level neonatal care units increases the risk of severe brain injury. Keeping these infants at lower level units after birth also results in a higher risk of death, compared to birth in a tertiary facility.
A study published in Neurology found that concussions can lead to lingering brain injuries even one year after athletes are cleared to return to play. Researchers used MRI scans to compare the brains of concussed and healthy athletes, finding reduced blood flow and signs of tissue swelling in concussed athletes.
Research by Imperial College London and the University of Turku found that premature babies transferred to a different hospital within 48 hours had an increased risk of severe brain injury. In contrast, staying in a hospital with a specialist neonatal unit was associated with a lower risk of death.
A global trial has found that early treatment with tranexamic acid can reduce deaths from traumatic brain injuries by up to 20%, depending on the severity of injury. The study, published in The Lancet, included over 12,000 patients and showed a significant benefit in those with mild and moderate injuries.
A recent study has found greater signs of blood vessel damage than nerve damage in traumatic brain injuries, challenging the ongoing hypothesis that blunt force causes nerve damage. The researchers' discovery could influence the development of new treatments and therapies for TBI.
Researchers discovered traumatic microbleeds are a form of blood vessel injury following brain trauma, and predict poor outcomes. The study found that patients with severe head injuries were more likely to have microbleeds and greater disability.
Between 2008 and 2014, approximately 1,972 firearm-related eye injuries occurred in patients under 21, mostly sight-threatening and associated with severe trauma. Black patients were more likely to be injured in assaults, while white patients had a higher rate of self-inflicted firearm-related injuries.
A study of adolescent and adult athletes found evidence of damage to the brain's protective barrier, without a reported concussion. The researchers detected leaks in the blood-brain barrier using advanced MRI protocol and biomarkers, suggesting that mild impact can still cause significant trauma.
Researchers at CU School of Medicine have developed a new imaging method called 'fast MRI' that can effectively identify traumatic brain injuries in children without exposing them to ionizing radiation or anesthesia. The study found that fast MRI was completed successfully in nearly all cases, with accuracy similar to CT scans.
Researchers found that female athletes had longer recovery trajectories and experienced more symptoms than males due to delayed presentation to specialist care. The study suggests that inequities in medical and athletic trainer coverage on the sidelines may contribute to these delays.
Dr. Kristin L. Garlanger has been awarded the Ernest Bors, MD Award for Scientific Development by the Journal of Spinal Cord Medicine. Her research explores functional outcomes in patients with co-occurring traumatic brain injury and spinal cord injury, shedding light on ways to tailor rehabilitation protocols to improve outcomes.
A new study of US cyclist injuries from 2002-2012 found that men and ethnic minorities were less likely to wear cycle helmets. The research also showed that helmet use significantly reduced the severity of injuries, hospital stay, and mortality rates for cyclists.
Researchers identified NFIA as a central regulator of reactive astrocytes in brain injury. The study showed that NFIA plays different roles depending on the type of injury and region affected, hinting at an extensive reservoir of reactive astrocyte responses.
A study using sensor-enabled mouthguard technology and dynamic contrast-enhanced MRI found that repetitive impacts cause damage to small blood vessels in the brain, leading to 'leaky' blood vessels visible on MRI scans. The research aims to improve player safety in sports with robust return-to-play guidelines.
A study by Purdue University researchers suggests that urine analysis can provide faster diagnosis and treatment for traumatic brain injuries, which could lead to improved outcomes for soldiers and athletes. The test checks for elevated levels of acrolein in the urine within seven days of injury.
Researchers studied tau protein accumulation after a single traumatic brain injury (TBI) in 32 individuals and found increased deposition of tau associated with poorer memory and cognitive performance. Higher tau levels were also linked to more severe neurodegeneration and damage to the brain's white matter.
Researchers at Imperial College London visualized protein 'tangles' associated with dementia in patients who suffered a single head injury, showing collective likelihood of tau tangles and nerve damage. The study may accelerate treatment development by enabling medics to monitor tau protein levels.
Researchers found a correlation between facial emotion recognition deficits and poor community integration in individuals with moderate to severe traumatic brain injury. Those with impaired emotional recognition displayed reduced community integration, suggesting a potential barrier to social isolation.
A study of US eScooter injuries found that most injured riders are men aged 20-40, with high rates of drug and alcohol use, and lack of helmet wear. The injury toll is expected to rise as eScooter popularity increases.
Researchers have developed a self-assembling peptide hydrogel that increases blood vessel regrowth and neuronal survival in rats with traumatic brain injuries. The treatment also improves the survival of brain cells and shows signs of new blood vessel formation.
A survey of over 3,400 former NFL players reveals a strong link between concussion history and low testosterone and erectile dysfunction. Researchers found that even relatively few concussion symptoms can increase the risk of ED, and the condition may persist for decades after injury.
A study of 8,857 children found that recreational sports led to more serious head injuries than contact sports, with bike riding and skateboarding causing the most frequent serious injuries. The research highlights the need for greater awareness and safety measures in recreational sports to prevent head injuries in children.