Articles tagged with Brain Injuries
Researchers at the University of Göttingen studied how blocking certain enzymes affects brain adaptability in healthy and diseased mice. In healthy mice, inhibiting these enzymes blocked neuronal plasticity, while in stroke-affected mice, it restored lost plasticity.
A three-year study found that taking older blood thinners like warfarin and clopidogrel, as well as aspirin, significantly increases the risk of delayed intracranial hemorrhage. Researchers recommend follow-up CT scans for patients taking these medications after head trauma.
Research led by Durham University found former pro rugby players more likely to show signs of depression, anxiety, and irritability after retirement. Players with multiple concussions were almost twice as likely to report these symptoms.
Young veterans with mTBI experience premature cognitive decline in specific domains, matching elder normative scores and early-stage Parkinson's patients. The study highlights the significant negative impact of mTBI on cognitive function compared to healthy non-veterans.
A peer-reviewed study published in Life journal proves Reflex identifies biomarkers for concussions, enabling accurate clinical diagnosis and decision-making. The study, conducted by Purdue University, uses pupillary light reflex to measure concussion patients' recovery and prevent compounding injuries.
A USF Health study reveals that fibrinogen can directly interact with neurons, leading to inflammation and neurodegeneration in Alzheimer's disease and traumatic brain injury. The researchers found that blocking the binding of fibrinogen to its receptors may alleviate short-term memory problems associated with these diseases.
Patients with stroke symptoms can be quickly assessed for traumatic injuries without delaying brain imaging and treatment. The novel STRAUMA activation enables rapid evaluation of both stroke and trauma to facilitate timely administration of life-saving interventions.
A study of 193 patients with severe acute brain injury found significant discordance between physicians and families regarding patient recovery prospects. The disagreement often stemmed from differing expectations about the likelihood of independence after injury.
A pilot study examines graph-theoretical properties of brain networks in traumatic brain injury and controls, showing association with balance impairment and structural damage. The study uses EEG-based functional connectivity measures during a balance perturbation task to explore underlying neural mechanisms.
Research found that horse riding has a higher risk of serious injury compared to other high-risk activities. The study analyzed data from the US Centers for Disease Control and Prevention and Trauma Surgery & Acute Care Open journal, revealing that chest injuries were the most common site, but head and neck injuries were the most lethal.
The study analyzed data from 680 patients aged 1-17 who were involved in ATV or dirt bike crashes. Helmeted riders had lower rates of neurosurgical consultation, intracranial injury, moderate or severe traumatic brain injury, and required fewer neurosurgical procedures compared to unhelmeted riders.
Researchers at Keck School of Medicine will collect and analyze imaging data from over 1,300 children nationwide to identify biological markers predicting recovery or persistent symptoms after concussion. The study aims to develop a diagnostic protocol for clinicians caring for pediatric patients with concussion.
The CARE Consortium has received $42.65 million in new funding to follow athletes for up to 10 years after concussive injury, examining the impacts of head injuries on brain health. The study aims to validate advanced biomarkers and identify neurobiological pathways contributing to long-term negative consequences.
The Charles Lazarus Children’s Abilities Center at Mount Sinai offers cutting-edge treatments for children with disabilities, including physical, occupational, and speech therapy. The center features state-of-the-art equipment and a multidisciplinary team of experts providing comprehensive care to children from birth to age 21.
Researchers found that viral, fungal, or bacterial infections impact blood vessel repair in the brain after traumatic brain injury (TBI) and cerebrovascular injury. Infected animals took longer to repair damaged blood vessels, leading to permanent cognitive dysfunction and brain damage.
Researchers at the University of Alabama at Birmingham discovered a small molecule that potently attenuates neuroinflammation in brain and glial cells. This finding presents a promising new approach to treat neurological diseases driven by neuroinflammation, such as stroke, spinal cord injury, and neuropathic pain.
A new study published in Science identifies a specific molecule, C1q, that plays a key role in the long-term effects of traumatic brain injury. The researchers found that an antibody treatment could prevent the development of negative outcomes such as sleep disruption and inflammation.
A randomized clinical trial of 125 young adults with concussions found that restricting screen time for 48 hours significantly reduced symptom duration. The study, published in JAMA Pediatrics, suggests that limiting screen time may be a useful strategy to accelerate concussion recovery.
Adults with a history of traumatic brain injury are at increased risk of using and misusing prescription opioids, with nearly 52% increased risk for use and over 65% increased risk for misuse. The findings support the 'Perfect Storm' hypothesis, suggesting that TBI increases vulnerability to pain and opioid risks.
Researchers at the University of Gothenburg generated a comprehensive transcriptional atlas of neonatal mouse meningeal leukocytes, showing that these cells play a crucial role in brain development and pathology. The study also identified novel immune cell subtypes involved in brain injury and provided new insights into the interaction...
A team of researchers at Washington University in St. Louis has received a $3.12 million NIH grant to study neurovascular recovery after stroke. They aim to develop new neurovascular imaging technology using two-photon fluorescence microscopy and photoacoustic microscopy to visualize blood oxygen delivery in response to neuronal activity.
A portable optical sensor system could diagnose traumatic brain injury severity in the field from a single drop of blood, potentially reducing costs and improving treatment outcomes
Researchers found subtle and chronic changes in the brains of young athletes with a history of concussions, including sharper declines in blood flow and microstructural changes. These findings suggest that athletes with a concussion history should be closely watched for worsening effects from repeated injuries.
Researchers investigated high schools' safety policies to protect student-athletes from heat, cardiac arrests, traumatic brain injuries and more. Thirty-eight states have adopted legislative changes improving safety for student-athletes, including West Virginia.
Researchers found that pituitary hormone ß-endorphin and Arg-vasopressin contribute to movement impairments on the opposite side of the body after a brain injury. Blocking these hormones may help treat movement problems following stroke or injury, targeting left and right sides differently.
A recent study from University of Gothenburg found that all participants achieved normalization of CNS injury biomarkers, regardless of previous disease severity or persistent neurological symptoms. This suggests that post-COVID-19 neurological sequelae are not due to active brain injury, contradicting previous findings.
Researchers found that high-dose gait training using a robotic exoskeleton can restore functional ambulation in individuals with moderate to severe hemiplegia caused by stroke. The study showed improvements in walking distance, speed, balance, and endurance, with no complications or falls reported.
A study of 44 elite rugby players found significant changes in white matter and volume over time. The research suggests that professional rugby participation may be associated with structural changes in the brain that could have long-term implications for player health.
Researchers followed 484 patients with moderate-to-severe TBI and found that among those in a vegetative state, 1 in 4 regained orientation within 12 months. This challenges early predictions of poor outcome and highlights the importance of considering long-term recovery possibilities.
A new NIH-funded study found that certain patterns on CT scans after mild traumatic brain injury can predict outcomes and guide treatment. The research identified three distinct sets of patterns, including bleeding into brain tissue and cerebrospinal fluid, associated with various short- and long-term outcomes.
Russian scientists have synthesized chemical compounds that activate intracellular mechanisms to combat neurodegenerative pathologies. These substances increase the survival of neuronal cells in cellular models of Alzheimer's disease and traumatic brain injury, offering a breakthrough treatment for brain diseases.
Researchers at UC Riverside's Brain Injury Lab have received significant federal funding to investigate the molecular mechanisms underlying traumatic brain injury and post-traumatic epilepsy. Two graduate students, Laura Dovek and Susan Nguyen, have each won prestigious fellowships to study the role of immune receptors in the developme...
A recent study published in the Journal of Head Trauma Rehabilitation found that two-thirds of patients with traumatic brain injury (TBI) remain married to their spouse 10 years after the injury. The study analyzed data from 1,423 patients and found that marital stability was higher for those who were older, female, and had no problema...
A recent study of over 3,500 participants found that traumatic brain injuries are increasing in the over-65 age group, with falls as the most common cause. The study highlights the need for prevention measures, such as training programs for safe walking and redesigning homes to remove tripping hazards.
A new signaling pathway has been identified in fruit flies that causes neural cells to divide after damage, a process similar to what occurs in Alzheimer's Disease. Researchers hope to apply this knowledge to prevent abnormal cell division and neuronal death in humans.
Researchers discovered a novel interaction between proteins hevin and calcyon, which promotes synaptic contacts and reorganization in the brain. This interaction helps to improve recovery from brain injury, particularly in adults, by reducing neuroinflammatory response-induced proteases and promoting early stages of recovery.
A consensus statement by a US expert panel suggests that strict rest after a sports-related concussion can slow recovery and prolong symptoms. Most athletes will recover fully within 2-4 weeks, but factors such as previous concussions, loss of consciousness, and underlying conditions may complicate recovery.
A new international study has identified a drug that can halt the progression of chronic traumatic encephalopathy (CTE) in sportspeople who sustain repeated head injuries. The treatment was successfully tested in animal models and shows promise for preventing neurological problems associated with CTE, which affects cognition and behavior.
A study analyzing e-scooter injuries in Berlin found that most incidents occur on weekends, at night, and are caused by loss of control or kerb jumping. The researchers advocate for stricter regulations, including helmet use, age limits, and technical modifications to reduce injury risk.
A recent study by Oregon Health & Science University found that people of color are more than twice as likely to die after a traumatic brain injury compared to white patients. The researchers analyzed over a decade of data and attributed the disparity to underlying social determinants such as diet, lifestyle, and access to healthcare.
A study in fruit flies and rat models reveals that traumatic brain injury disrupts nuclear transport machinery, leading to protein build-up and neurodegenerative diseases. Researchers identify a key enzyme and molecule involved in the process, highlighting a potential target for new treatments.
A new $2.3 million grant will support a five-year research project at UC Riverside, led by Viji Santhakumar, exploring the relationship between inflammation and abnormal neuron connections after brain injury. The study aims to identify potential early therapies to prevent epilepsy and memory issues following traumatic brain injury.
A study published in Archives of Rehabilitation Research and Clinical Translation found that prism adaptation treatment improves functional and cognitive independence scores for stroke survivors with spatial neglect. The treatment, which involves wearing goggles with optical prisms to shift motor movements, results in higher scores on ...
A recent study found that four out of five women in prison in Scotland have a history of head injury, mostly sustained through domestic violence. Women who had such injuries were more likely to engage in violent criminal behavior and had longer prison sentences.
A study published in the journal Concussion reveals that the use of cooling technology with PolarCap System hastened safe return to play for players of top Swedish hockey league teams. The treatment showed a median time to return to play of 7 days, compared to 12 days without cooling.
Researchers at UTA are combining nanoparticles and light waves to treat traumatic brain injuries on the battlefield. The goal is to create a synergistic effect with improved healing outcomes.
A new University of Michigan study reveals that nearly 1 in 4 adolescents reported at least one concussion in 2020, up from 20% in 2016. Concussion rates increased among Hispanic and non-Hispanic youth who participated in sports, contradicting emergency department data showing a decline in sports-related traumatic brain injuries.
Biomarker concentrations were elevated among personnel with longer duration of service, particularly without a diagnosed brain injury or concussion. Repeated exposure to low levels of blast has been linked to symptoms such as headaches, fatigue, and tinnitus.
A third of children and adolescents experience mental health problems after a concussion, which can persist for several years post-injury. The review emphasizes the importance of evaluating mental health as part of standard pediatric concussion assessment and management.
A new study by researchers at the VA Portland Health Care System found that morning bright light therapy improved physical and mental symptoms for veterans with traumatic brain injury. The therapy showed significant benefits in cognitive function, sleep, depression, and neuropsychiatric trauma symptoms.
A new study finds that traumatic brain injuries (TBIs) share similar degenerative changes in the brain as Alzheimer's disease, particularly in memory and decision-making areas. The research identified comparable patterns of gray and white matter degradation after TBI, which may help predict Alzheimer's risk.
A new tool called PhenoBench standardizes data analysis for traumatic brain injury (TBI), enabling researchers to identify patient subgroups for personalized care. The study aims to provide tailored treatments that improve recovery and reduce long-term consequences of TBI.
A new study from the VA, Regenstrief Institute, and IUPUI analyzed healthcare utilization among TBI patients and found that a quarter were super-utilizers. The research also identified disparities in care based on health insurance and residency status.
A new visio-vestibular examination (VVE) has been found to enhance concussion diagnosis and management in young athletes. The VVE involves brief eye movement and balance tests identifying deficits in brain function involving the visual and vestibular systems.
Researchers developed an ultrasensitive assay to measure cathepsin B in blood, detecting the biomarker for a range of disease states. This breakthrough aims to improve diagnosis and treatment strategies for conditions such as traumatic brain injury.
Researchers at the University of Georgia have developed a hydrogel, known as 'brain glue,' that mimics the composition and mechanics of the brain. The gel has been shown to protect against loss of brain tissue after severe TBI and may aid in functional neural repair.
A University of Birmingham-led study has identified a method to accurately diagnose concussion using saliva, providing a new laboratory-based non-invasive salivary biological concussion test. The test uses biomarkers that can indicate if a player has been concussed and provide insights into the body's response to injury.
Researchers have identified distinct chemical signatures for concussion in the spit of elite male rugby players, suggesting a potential non-invasive diagnostic test. The findings could help diagnose concussions at all levels of participation, particularly at grass-roots levels where medical assessments are not readily available.
Researchers have developed a highly sensitive pressure sensor cap that can help reveal whether a helmet is a perfect fit for an individual player's head. The device uses fabric-based sensors that map pressure in real-time, providing valuable information on helmet fit and potentially reducing the severity of sports-related head injuries.
A Northwestern Medicine pilot study found that high levels of progesterone during the menstrual cycle can reduce stress after a concussion and speed recovery. Increased blood flow to the brain is also linked to lower stress symptom levels, providing new insights into how female athletes may recover from concussions.