A study in biomechanics measures the impact of head-first, hand-first, and feet-first diving to provide data-driven recommendations for safe diving. The researchers found that spinal cord and neck injury is likely above eight meters in a head-first dive, while knee injury is likely above 15 meters with feet-first diving.
Researchers at Arizona State University have discovered molecular signatures associated with acute and chronic phases of traumatic brain injury (TBI). The study aims to address current limitations in TBI diagnosis and treatment by identifying biomarkers and understanding the blood-brain barrier's role in drug delivery.
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A study found an association between prior head injury and a reduced sense of smell in older adults, particularly those with multiple injuries and more severe trauma. The researchers suggest that repeated blows to the head may damage olfactory receptors, leading to anosmia.
A new study from Tel Aviv University found a promising treatment for long-term COVID-19 symptoms using Hyperbaric Oxygen Therapy (HBOT). Patients treated with HBOT showed significant improvement in cognitive function, attention, and executive functions.
A multi-site trial found OP-101 to be effective in reducing inflammatory markers and markers of neurological injury, with improved outcomes for patients. The study showed a significant reduction in the composite outcome of mechanical ventilation or death at 30 and 60 days after treatment.
Kessler Foundation researchers will conduct studies on brain injury, knee osteoarthritis, and pediatric cerebral palsy using mixed-reality technology, robotic exoskeletons, and cycling feedback systems. The grants aim to improve safety and mobility for elderly individuals with cognitive impairments and those with neurological disorders.
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Researchers have discovered neural plastic changes that can improve functional recovery after a cervical spinal cord injury. Using an optogenetic neuromodulation strategy, they found that the intact corticospinal system in the opposite side of the brain and spinal cord can be modulated to take over control of the damaged forelimb, resu...
Biomedical engineers have created a novel 3D synthetic structure that mimics the extracellular matrix, guiding neural progenitor cells and promoting their differentiation. The results show promise for developing brain-healing treatments, including biogels that can repair and regrow brain tissue after a stroke or other trauma.
A major public health concern, consumer product-related traumatic brain injuries have increased significantly in school-aged children, peaking in 2012 and declining in boys but increasing substantially among girls. The study highlights the need for awareness and training on screening and treatment of TBI in children.
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A new study found that subtle brainwaves detectable with EEG are the strongest predictor of eventual recovery for brain-injured patients who appear unresponsive. Covert consciousness, detectable through customized artificial intelligence software, is linked to higher and faster rates of recovery.
A new study found that people with severe speaking difficulties pay more attention to hand gestures when their verbal communication is impeded. This highlights the importance of incorporating gestures into therapy for individuals with aphasia.
Astrocytes in the thalamus play a key role in susceptibility to seizures after brain injuries. Targeting a specific protein, GAT3, in these cells may prevent long-term damage.
A new study by University of Missouri found that Black nursing home residents and those under 65 are significantly more likely to experience repeat hospital transfers. This phenomenon can be attributed to various factors including 'full-code' status regarding end-of-life care, comorbidities, and inadequate staffing. The study suggests ...
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Researchers evaluated 435 employed adults with mild traumatic brain injury over 12 months, finding a significant association between return to work and improved economic outcomes. The study suggests that employer assistance plays a crucial role in supporting workers' transitions back to the workforce.
Researchers developed a new method using magneto-active polymers to study cellular behavior and replicate complex biological processes. The system allows for real-time control of mechanical forces on cells, enabling the analysis of mechanisms behind traumatic injuries and tissue damage.
A study by Stephen T. Casper examines how sports slang, such as 'punch-drunk,' influenced the conceptualization and treatment of brain injuries. The research reveals a culture that stigmatized sufferers and normalized male violence, making it difficult for medical professionals to diagnose and treat neurodegenerative disease.
A new therapy called Cognitive Behavioral Therapy for Headache (CBTH) significantly reduced related disability in veterans following a traumatic brain injury. It also showed comparable reductions in co-occurring symptoms of post-traumatic stress disorder (PTSD), with low drop-out rates and ease of use for therapists.
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A new study by Ohio State University researcher Michael Betz found that fighting in the NHL does not reduce violent penalties, but rather increases them. Fights lead to more penalties, not less, contradicting league officials' arguments for keeping fighting in the game.
Researchers created a new gel that can protect fragile objects like eggs by adding starch to gelatin, reducing impact force up to 15%. The gel's flexibility and impact absorption make it suitable for sports equipment, defense materials, and packaging.
A new study published in CMAJ found that youth hockey players with more years of bodychecking experience had a significantly higher risk of concussion than those with less experience. The researchers collected data on 941 players aged 15-17 and found that concussion was the most common injury, making up over one-third of all injuries.
Researchers at Champalimaud Centre found that Wg/Wnt signaling molecule helps mount a regenerative response to brain damage. Neurons sense tissue distress, triggering dormant neural stem cells to activate and produce new neurons.
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Researchers mapped neural connections throughout entire brain after TBI, finding increased connections to inhibitory neurons but disrupted relationships. Transplanted interneurons showed promise in reconnecting damaged brain regions.
Children using trampoline centers are at a higher risk of serious injuries and hospital admissions compared to those using trampolines at home. Mandatory safety standards for trampoline centers are urgently required, highlighting the need for public awareness and evidence-based safety measures.
Research reveals that healthy brain temperature varies significantly by brain region, age, sex, and time of day. Daily brain temperature cycles strongly correlate with survival in traumatic brain injury patients, suggesting potential improvements in understanding and treatment of brain injuries.
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Researchers develop targeted delivery system to boost regulatory T cells, which manage inflammation and reduce brain damage. The treatment increases IL2 levels, allowing regulatory T cells to survive and reducing cognitive impairment.
A team of researchers, backed by a $8 million US Department of Defense grant, aims to identify potential treatment options and ways to block brain inflammation caused by repetitive blast exposures. They will use advanced brain imaging and blood sampling to understand the role of neuroinflammation in TBI.
Researchers at FAU's Schmidt College of Medicine are conducting a two-year study to investigate emergency department-based prevention strategies for high-risk older patients. The project aims to identify effective fall prevention strategies that target limited resources to improve patient outcomes, safety, and reduce healthcare costs.
Researchers will investigate neural mechanisms during learning in individuals with traumatic brain injury (TBI) with and without clinical depression. The study aims to identify new knowledge about the effect of depression on the injured brain, which may lead to interventions for rehabilitation.
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A novel preclinical drug has been developed to inhibit the kinase enzyme Cdk5, which is implicated in neuropsychiatric and neurodegenerative conditions. The drug, 25-106, is brain-permeable and shows promise in altering neurobehavior in mice with anxiety-like behavior.
A new study suggests that oxidative stress overactivates a glucose metabolism enzyme in the developing hippocampus, impairing learning and memory. However, inhibiting this enzyme can reverse cognitive deficits, paving the way for treatment of neonatal brain injuries.
A recent study suggests that concussion symptoms in children may be caused by multiple types of brain damage, leading to varying sets of symptoms. The research found complex relationships between brain damage and symptoms, which could lead to improved treatments for individual patients.
Researchers found signs of concussions and head trauma in the brains of deceased headbutting muskoxen and bighorn sheep. The study provides insights into human injuries and opens the possibility that studying these animals could help researchers understand and reduce traumatic brain injuries.
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A new study by McGill University researchers has shed light on the complex relationships between concussion symptoms and brain damage in children. The findings suggest that certain combinations of brain injury can lead to specific symptoms, such as attention difficulties and sleep problems.
A team of researchers has developed a novel method using infrared imaging to assess glymphatic function, which is crucial for understanding neurological conditions. The technique allows for the measurement of temporal dynamics of glymphatic functions and provides insights into brain fluid exchange and clearance.
A new study published in Neurology found that people hospitalized for major traumatic brain injury (TBI) may have a higher risk of developing dementia. After adjusting for other relevant dementia risk factors, researchers found a 1.5 times greater risk of dementia among those with major TBI compared to those without.
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A study from Edith Cowan University reveals that electrical stimulation on specific nerves and relaxation techniques can reduce neural amplification in the spinal cord, which may help alleviate involuntary muscle spasms. These methods could provide a non-pharmacological alternative to current treatment options.
Researchers discovered a link between traumatic brain injuries and changes in the gut microbiome, suggesting a potential diagnostic tool for concussions. The study found two bacterial species that dropped significantly after concussions, indicating a correlation with traumatic brain injury-linked proteins in the blood.
A new study in mice suggests that forcing the turnover of specific immune cells called microglia can reverse cognitive and behavior problems associated with concussions. The findings provide a potential pathway for developing post-concussion therapies to ward off long-term mental health issues.
Researchers developed a new method using actigraphy to monitor sleep-wake cycles in children with brain injury during inpatient rehabilitation. The study found lower rest-activity ratios, suggesting poorer sleep-wake regulation and lower functional status.
Astrocytes, comprising nearly half of all brain cells, have been found to perform an electrically active function that influences neurotransmitter release and brain disease pathology. This discovery opens new avenues for neuroscience research and potential treatments for conditions like Alzheimer's and epilepsy.
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A team of researchers developed a prognostic model using automated brain scans and machine learning to predict survival and recovery in severe TBI patients. The model accurately predicted risk of death and unfavorable outcomes at six months after the injury, potentially improving clinical decision-making and patient care.
Researchers investigated the use of intranasal human milk as a stem cell therapy for preterm infants with intraventricular hemorrhage. The study found that preterm infants could tolerate nasal milk therapy without major safety events, paving the way for further research on long-term outcomes.
Researchers identified two genes associated with recovery within the first 24 hours after stroke, linking neuronal excitability to stroke outcomes. Genetic evidence suggests that calming overexcited neurons may protect the brain after a stroke.
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Dr. Aaron Phillips received the 2021 Turnbull-Tator Award for his innovative research on neuroprosthetic baroreflex controls after spinal cord injury. He aims to develop a widely available therapy to improve blood pressure stability and quality of life for those affected.
A new study suggests that people with epilepsy linked to head injuries are more likely to experience depression, PTSD, back pain, and other health conditions. Those with drug-resistant epilepsy associated with a head injury reported the lowest quality of life scores.
Researchers developed new method to visualize CNS fibroblasts and their intercellular interactions in the CNS. The technique provides a detailed picture of CNS fibroblasts, including their location, size, morphology, and gene/protein expression patterns.
A Rutgers study suggests the Sport Concussion Assessment Tool (SCAT) overestimates concussions and incorrectly identifies symptoms caused by intense exercise. The researchers found that players without a head impact exhibited similar symptoms to those with a concussion, highlighting the need for further studies on better assessing conc...
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A new study found that some symptoms commonly used to diagnose concussions, such as fatigue and neck pain, can be caused by intense exercise rather than a brain injury. The research highlights the need to consider these factors when assessing concussion in athletes on the field.
A clinical study from Lund University found that athletes with prolonged concussion symptoms have damaged nerves in the inner ear, particularly the vestibular nerve. This impairment leads to balance problems, dizziness, and difficulty focusing, affecting daily life.
Researchers have discovered a significant association between acute kidney injury and an increased risk of developing dementia in patients hospitalized with AKI. Early detection and monitoring may lead to improved outcomes for this high-risk population.
Researchers found severe brain inflammation and injury in COVID-19 patients, with neuron damage and death also present. The study suggests that nonhuman primates can serve as a proxy for understanding human neurological consequences of COVID-19.
This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...
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A study found that 25.3% of children with mild head injuries continue to suffer from persistent post-concussion syndrome for years, often misdiagnosed as ADHD or sleep disorders. The syndrome causes chronic symptoms like forgetfulness, memory problems, and sensitivity to light and noise.
A global study examining surgical management of traumatic brain injuries reveals regional disparities in causes, treatment, and patient outcomes. Hospitals in low-HDI settings often delay surgery and lack postoperative monitoring equipment.
A new study by Weill Cornell Medicine and colleagues found that most COVID patients regain consciousness after removal of respiratory support, but may take weeks to recover. The study also showed that patients who experienced low blood oxygen levels during treatment took longer to recover consciousness.
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A study published in the Journal of Head Trauma Rehabilitation found that service members who sustained combat-related traumatic brain injury (TBI) are at high risk of long-term disability. The odds of being on a trajectory of worse long-term outcome were 49 times higher for those with blast TBI compared to those with no blast exposure.
A study of 448,000 children aged 5-18 found that sustaining a concussion increased the risk of mental health issues, psychiatric hospitalization, and self-harm. The research highlights the potential long-term effects of concussions on young people's mental well-being.
The National Athletic Trainers' Association has updated its position statement to reduce intentional head-first contact behavior in American football players. The new recommendations address education and administration, skill development and behavior modification, rules and regulations, and technology and scientific research.
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Researchers at MUSC and University of Florida successfully visualize the complete human brain lymphatic system in living humans using a new non-invasive MRI technique. This breakthrough enhances our understanding of brain function and may provide insights into neurodegenerative diseases such as Alzheimer's.
Researchers from Tel Aviv University found that hyperbaric oxygen therapy (HBOT) relieves PTSD symptoms in treatment-resistant veterans, improving brain function and microstructure. The breakthrough study provides new hope for PTSD sufferers, offering an objective diagnostic tool and potential long-term improvements.