Articles tagged with Myocardial Infarction
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A new study has shown that bivalirudin is a safer and more effective anticoagulant than heparin for treating heart attack patients. The trial found that bivalirudin significantly reduced death, major bleeding, and thrombosis in patients undergoing percutaneous coronary intervention.
Researchers found that two common diuretics, chlorthalidone and hydrochlorothiazide, had no difference in cardiovascular outcomes among study participants. However, those taking chlorthalidone showed a reduced risk of heart disease and death by an average of 27% among patients with a history of heart attack or stroke.
A new study by Intermountain Healthcare found that following up a cardiac event with a statin prescription and cholesterol measuring blood test prevents 94% of patients from having or dying from a second cardiovascular event. Patients without follow-up care were at a 60% risk, compared to just 6% for those who received treatment.
Researchers at Intermountain Healthcare discovered that patients without standard modifiable heart risk factors who experience a heart attack fare better, with lower rates of revascularization procedures and subsequent major cardiac events. This finding highlights the need to identify patients at risk for an event before it happens.
Researchers have discovered a new role for VWF in regulating immune responses at sites of blood vessel injury, leading to potential treatment options for inflammatory and blood clotting disorders. The study found that VWF plays a key role in repairing damaged blood vessels, which could help prevent heavy bleeding and blood clots.
A new troponin test has been developed to help diagnose heart attacks more accurately. By detecting only large troponin molecules, the test can distinguish between heart attacks and other conditions such as renal insufficiency.
A recent study published in Nature Communications identified a root cause of chronic heart failure following a heart attack, revealing that iron drives the formation of fatty tissue in the heart. This discovery has the potential to prevent heart failure in nearly half a million people in the US and millions more worldwide.
A study found that living in a food desert increases the risk of heart attack, stroke, and early death for people with PAD. People with PAD living in food deserts were 17% more likely to experience a major cardiac event compared to those with better nutrition access.
Researchers tracked participants for almost 30 years and found a link between past exposure to intimate partner violence and future cardiovascular health. The study suggests that intimate partner violence is associated with a higher risk of heart attacks, strokes, and heart failure hospitalizations.
Researchers found that marital stress among younger adults (ages 18–55 years) is associated with poorer recovery after a heart attack. The study of over 1,593 participants showed that higher levels of marital stress were linked to reduced physical and mental health outcomes.
A study of over 2,600 young heart attack survivors found that those who experienced more perceived discrimination had a higher risk of worse health outcomes. The research suggests that perceived discrimination acts as a chronic stressor that adversely impacts cardiovascular disease.
A large UK Biobank study found that COVID-19 infection is associated with a heightened risk of poor cardiovascular health and death, particularly among those who require hospital admission. The risk remains elevated for some time after the initial infection.
Researchers at the University of Alabama at Birmingham have identified TBX20 as a vital regulator of direct human cardiac reprogramming. Adding TBX20 to existing cocktails improves contractility and mitochondrial function in reprogrammed heart muscle cells, suggesting a therapeutic potential for TBX20.
A study found that in people with significant kidney disease, psoriasis does not increase the risk of heart attack. After controlling for other risk factors, researchers found no association between psoriasis and heart attacks in patients with end-stage renal disease.
Researchers at CNIC have identified metoprolol as a neuroprotective agent after a stroke, greatly reducing cerebral inflammation and neuronal death. The study's findings suggest that metoprolol may also offer benefits in treating severe Covid-19.
Particle radioactivity from radon in air pollution increases toxicity and risk of death from cardiovascular disease, especially from heart attack and stroke. Researchers used spatiotemporal predictions to estimate exposure and found that higher gross beta-activity levels increased the risk of death from these conditions.
Researchers developed an AI algorithm to assess retinal vasculature, predicting cardiovascular disease and death. The model captured half to two-thirds of circulatory disease deaths in those most at risk, outperforming traditional risk frameworks.
Researchers discover that oxytocin stimulates stem cells to migrate and develop into cardiomyocytes in zebrafish and human cell cultures. This could lead to the regeneration of damaged hearts after a heart attack. The study found that oxytocin also activates EpiPCs, which can replenish lost cardiomyocytes.
The Leducq Foundation has awarded $7.5 million to UVA researchers, led by Mete Civelek, to investigate sex differences in atherosclerosis and $8 million to Coleen McNamara to advance immunotherapy for cardiovascular disease. These projects aim to improve understanding of heart disease and develop new treatments.
A new study found that only around half of older adults with hypertension regularly check their blood pressure at home. Those who received a healthcare provider's recommendation to do so were three and a half times more likely to monitor their blood pressure regularly.
Research found that people with HIV who also have untreated hepatitis C virus have a higher risk of heart attack as they age. The study analyzed health data from 23,361 people with HIV and found that those co-infected with hepatitis C had a significantly increased risk of heart attack compared to those with HIV alone.
A randomized controlled trial found that virtual reality immersion reduced the need for sedatives during hand surgery, leading to lower doses of propofol and shorter post-operative lengths of stay. Patient satisfaction remained unchanged, but discharge times were significantly shorter.
A recent study by the American Heart Association highlights that poorly controlled high blood pressure is a leading cause of cardiovascular emergencies in the US. The study analyzed over 20 million emergency department visits and found that 13% were for essential hypertension, which led to hospital admission less than 3% of the time.
A Brazilian study analyzed risk factors for heart attacks and found that high blood sugar had the most significant impact on mortality. Reducing smoking prevented most deaths from cardiovascular disease, while lowering diabetes incidence could have saved up to 5,000 lives over a decade.
The PASCAL transcatheter valve repair system showed non-inferiority compared to MitraClip in treating significant symptomatic DMR. Patients experienced improvements in functional and quality-of-life outcomes.
A new study published in the Journal of the American Heart Association found that individuals with autoimmune diseases are at a higher risk of complications after a heart attack. The research emphasizes the importance of controlling cardiovascular disease risk factors and developing personalized treatment plans for this population.
A prospective study in the Canadian Journal of Cardiology found that dedicated women's heart centers can significantly improve clinical and psychological outcomes for women with myocardial ischemia. The study, which followed 154 patients, showed a significant decrease in chest pain frequency and improved quality of life after attending...
A large French study found a potential direct association between higher artificial sweetener consumption and increased cardiovascular disease risk. The researchers suggest that these food additives should not be considered a healthy alternative to sugar.
A study suggests that adopting the DASH diet may have the greatest impact on reducing cardiovascular disease among people with stage 1 hypertension. The research estimates that this lifestyle change could prevent 15,000 heart disease events among men and 11,000 among women.
A large retrospective study found that visceral fat area from fully automated and normalized abdominal CT analysis predicts subsequent myocardial infarction or stroke in Black and White patients. The study suggests that body composition analysis using machine learning could be widely adopted to add prognostic utility to clinical practice.
A new study published in the Journal of the American Heart Association found that low physical function after age 65 is associated with a greater risk of developing heart attack, heart failure, and stroke. The study used the Short Physical Performance Battery (SPPB) test to assess physical function in 5,570 adults over 75 years old.
Scientists have discovered three proteins with therapeutic potential to prevent cardiac damage and preserve cardiac function after a heart attack. The proteins, Chrdl1, Fam3c, and Fam3b, were identified through an innovative technology called FunSel that screens human proteins for protective effects.
Researchers use human tissue models to study myocardial infarction, a leading cause of mortality worldwide. These models allow for early detection of discrepancies between animal and human responses, enabling faster and safer clinical trials.
A clinical trial found that long-term use of evolocumab led to further reductions in cardiovascular events compared to shorter treatment. Participants who received evolocumab for over 5 years had lower risk of cardiovascular death, myocardial infarction, stroke, and hospitalization.
A study published in Circulation found that moderate or vigorous physical activity can lower the risk of developing heart failure. The research, which analyzed data from over 94,000 adults, suggests that increasing physical activity duration and intensity may provide greater protection against heart failure.
A study published in The Lancet reveals that AI-based risk profiling can improve treatment outcomes for women with heart attacks. By accounting for sex-related differences, the novel score refines current risk models and reduces mortality rates among female patients.
A case-control study found that pregnant women with higher folate levels are at a lower risk of having children with congenital heart disease. The researchers measured red blood cell folate levels and found that those with CHD had significantly lower median levels than those without CHD.
Researchers developed a polygenic risk score to predict sudden cardiac death in coronary artery disease patients. The study found that patients with high genetic risk scores had a 77% increased risk of sudden cardiac death.
Researchers led by Jianyi Zhang aim to find key pathways for reprogramming adult heart muscle cells to proliferate in response to a heart attack, potentially leading to improved heart attack recovery through growth of new heart muscle cells. The grant will fund three projects at UAB and two other universities.
Symptoms of cardiovascular diseases, including heart attack and heart failure, can profoundly affect quality of life. The American Heart Association scientific statement highlights the importance of tracking symptoms to detect changes and progression.
A new scientific statement from the American Heart Association finds that social isolation and loneliness are associated with a 30% increased risk of heart attack or stroke. Younger adults, including Gen Z, experience increased social isolation and loneliness due to higher social media use and less in-person engagement.
A new study found that people taking beta-blockers or antiplatelet medications are more likely to have heart attacks during hot weather. The study, which analyzed data from 2,494 cases in Germany, suggests that these medications may render some individuals more vulnerable to heat-related heart attacks.
A new analysis from the Family Heart Foundation shows that only 31.3% of individuals with familial hypercholesterolemia (FH) in its database had been diagnosed as of June 2020. This represents a significant increase since 2016, but highlights the ongoing challenge of diagnosing and managing the condition.
A study published in the European Heart Journal found that making small behavioral changes can significantly reduce cardiovascular risk. Participants who received a lifestyle intervention showed improvements in physical activity, diet, and sedentary time, leading to decreased blood pressure and cholesterol levels.
Researchers at Max Delbrück Center for Molecular Medicine found that zebrafish can regenerate heart tissue after injury due to activated fibroblasts. The fibroblasts, which temporarily enter an activated state, read a series of genes responsible for forming proteins, enabling the regeneration process.
Researchers found that short bouts of reduced circulation with a blood pressure cuff can boost vascular and cardiac functions, lower blood pressure, and reduce the heart's workload. This technique, known as remote ischemic preconditioning, may be beneficial for people at high risk of heart attacks and strokes.
A study found ranolazine reduces inflammation and atherosclerotic plaques in blood vessels, lowering the risk of heart attack or stroke. The established drug also has an anti-inflammatory effect, reducing chronic vascular inflammation.
A new study published in Neurobiology of Sleep and Circadian Rhythms found that shift work can lead to long-lasting health effects, including increased severity of strokes. The research, led by Texas A&M University, suggests that disrupted internal body clocks can alter gut and brain interactions, leading to worse stroke outcomes.
A new Mount Sinai study reveals that young Black adults are twice as likely to have atherosclerosis as their Hispanic counterparts. Researchers used comprehensive questionnaires and 3D vascular ultrasounds to determine cardiovascular risk scores, finding significant discrepancies between the groups.
A long-term study of 3,926 adults with CKD found that higher levels of physical activity reduced the risk of atherosclerotic events, new-onset heart failure, and death. The association was strongest for incident peripheral arterial disease and reinforces current guideline recommendations.
A study found that rates of serious complications associated with shoulder surgery are low, but one in 26 patients need further surgery within a year. The effectiveness of some shoulder procedures is doubtful at best, according to experts.
Researchers identified glucocorticoids as a key factor inhibiting cardiac regenerative capacity after heart attacks. The study showed that deleting or blocking the glucocorticoid receptor increased heart muscle cell replication and regeneration.
Researchers discovered increased cell cycle activity and proliferation in cardiomyocytes after heart surgery, allowing for remuscularization of the left ventricle. The study identified key genes involved in pathways regulating heart development and cell proliferation.
A new gene, RAP1GAP2, has been identified as a potential contributor to the disparity in heart disease diagnosis and treatment between men and women. The study aims to analyze how this gene affects cardiac disease risks among women of different racial and ethnic groups.
Research found significant disparities in cardiac rehabilitation participation by race/ethnicity regardless of income. Cardiac rehabilitation programs combine physical activity with counseling to improve recovery after a major cardiovascular event.
Researchers found that invasive therapy for non-ST segment elevation myocardial infarction in patients with CKD is associated with lower mortality and reduced risk of cardiac events. The study challenges the dominant practice of offering medical management instead of invasive therapy for this population.
Researchers at Ohio State University created a mathematical model that assesses the efficacy of immunomodulatory drugs in treating myocardial infarctions. The study found that certain combinations of these drug inhibitors were more efficient at reducing inflammation, offering new possibilities for improving patient outcomes.
Researchers at the University of Houston have made a groundbreaking discovery in repairing and regenerating heart muscle cells in mice. The technology uses synthetic mRNA to deliver mutated transcription factors, which increases the replication of cardiomyocytes. This finding has the potential to become a powerful clinical strategy for...
A novel study published in the Canadian Journal of Cardiology demonstrates that Nordic walking provides greater long-term improvements in functional capacity compared to high-intensity interval training and moderate-to-vigorous intensity continuous training. Nordic walking engages core, upper, and lower body muscles, resulting in a sig...
A new SPECT imaging system performs scans 10-100 times faster than current systems, offering better image quality and increased patient throughput. The self-collimation concept improves traditional SPECT imaging by reducing scan time and radiation exposure.