A study published in the Journal of the National Cancer Institute found that proteins delivering leucine to prostate cancer cells are therapeutic targets. Inhibition of these proteins inhibits nutrient signaling pathways and over 100 metastasis-related genes, leading to cell cycle inhibition and reduced tumor growth.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateSep 19, 2013
The National Cancer Institute has awarded a five-year, $11.3 million competitive grant renewal to Fred Hutchinson Cancer Research Center to lead the Pacific Northwest Prostate Cancer SPORE consortium. The consortium aims to unravel molecular mechanisms and develop precision-medicine approaches for prostate cancer treatment.
A pilot study found that comprehensive lifestyle changes increased telomere length by an average of 10%, while control group telomeres decreased by 3%. The study suggests that such lifestyle changes may significantly reduce the risk of diseases and premature mortality.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateSep 16, 2013
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
The Wistar Institute has received a $1.5 million grant from the US Department of Defense to prepare its potential new prostate cancer drug Gamitrinib for trial in humans. The three-year grant will cover the costs of developing the data necessary to allow Gamitrinib's use in the clinic.
A new three-gene biomarker can accurately predict which low-risk prostate cancers will become aggressive, helping doctors determine whether men need active surveillance or invasive treatment. The test has shown promising results in a retrospective study of 43 patients, and further clinical trials are planned.
SourceColumbia University Irving Medical Center·JournalScience Translational Medicine·DateSep 11, 2013
A recent study by researchers at Fred Hutchinson Cancer Center has discovered a link between mutations in the BTNL2 gene and an increased risk of developing prostate cancer. The study found that rare variants of this gene are associated with both hereditary and sporadic cases of prostate cancer.
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A genetic mutation in the androgen-synthesizing enzyme 3βHSD1 enables tumors to produce their own supply of androgens, leading to the growth of castration-resistant prostate cancer. This discovery could lead to the development of biomarkers and targeted therapies for personalized medicine.
Researchers found a 59% reduced risk of prostate cancer recurrence and/or progression in men who consumed four or more cups of coffee per day. The study suggests that bioactive compounds in coffee may have anti-inflammatory and antioxidant effects, but further research is needed to understand the mechanisms underlying the results.
SourceFred Hutchinson Cancer Center·JournalCancer Causes & Control·DateAug 26, 2013
A new GE technology uses pyruvate levels to detect prostate tumors in real time, providing a safe and non-invasive way to assess cancer progression. The technology has shown promising results in a clinical study of 31 patients with prostate cancer.
SourceUniversity of California - San Francisco·JournalScience Translational Medicine·DateAug 15, 2013
A study found that prostate cancer aggressiveness is established at tumor formation and does not change over time. The proportion of patients diagnosed with advanced-stage cancers decreased by more than six-fold after widespread PSA screening, while high Gleason grade cancers remained stable.
SourceAmerican Association for Cancer Research·JournalCancer Research·DateAug 14, 2013
A collaborative study identifies PRNCR1 and PCGEM1 as long non-coding RNAs that activate androgen receptors, leading to cancer growth and resistance to treatment. The study provides a new target for therapies and offers hope for developing more effective treatments for aggressive prostate cancer.
SourceUniversity of California - Davis Health·JournalNature·DateAug 14, 2013
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A long-term study confirms that finasteride reduces the risk of prostate cancer by 43% in low-grade tumors and by 30% overall. This means thousands of men can avoid unnecessary treatments and burden on society.
SourceUniversity of Texas Health Science Center at San Antonio·JournalNew England Journal of Medicine·DateAug 14, 2013
A new therapeutic approach to treating prostate cancer has been identified through a study on the FoxM1 protein. Depletion of FoxM1 in prostate epithelial cells inhibits tumor cell proliferation, metastasis, and new blood vessel formation.
SourceCincinnati Children's Hospital Medical Center·JournalJournal of Biological Chemistry·DateAug 1, 2013
Researchers identified Skp2 inhibitor that blocks malignancy-promoting effects, shrinks tumors in preclinical studies. The compound suppresses prostate cancer stem cells, which play a role in cancer initiation and progression.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalCell·DateAug 1, 2013
Researchers at Sanford-Burnham Medical Research Institute have identified a novel mechanism of action for SMIP004, which specifically kills prostate cancer cells by interfering with mitochondrial function. The compound's effects were found to be particularly promising for treating castration-resistant prostate cancer.
SourceSanford Burnham Prebys·JournalOncoTargets and Therapy·DateJul 30, 2013
A study found that both web-based and print-based decision aids significantly improved prostate cancer knowledge and reduced decisional conflict among patients. The tools offered flexibility for patients and providers, with increased satisfaction reported among those using print decision aids up to 13 months after treatment.
SourceJAMA Network·JournalJAMA Internal Medicine·DateJul 29, 2013
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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A Swedish data-sharing campaign led to a significant decrease in unnecessary medical tests for low-risk prostate cancer patients. The study suggests that curtailing unneeded medical tests is achievable and offers insights into the importance of implementing guidelines and providing feedback to practitioners.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJNCI Journal of the National Cancer Institute·DateJul 23, 2013
A study of over 10,000 men with nonmetastatic prostate cancer found that use of androgen deprivation therapy (ADT) was associated with a significantly increased risk of acute kidney injury. The association remained consistently elevated across different types of ADTs, particularly in the first year of treatment.
Researchers at Albert Einstein College of Medicine have found that nerves play a critical role in both the development and spread of prostate tumors. The study suggests that targeting the autonomic nervous system may lead to novel therapies for preventing and treating prostate cancer.
SourceAlbert Einstein College of Medicine·JournalScience·DateJul 11, 2013
A large prospective study by Fred Hutchinson Cancer Center scientists confirms the link between high blood concentrations of omega-3 fatty acids and an increased risk of prostate cancer. High-grade prostate cancer tumors are more likely to be fatal, and the study found a 71% higher risk for high-grade prostate cancer.
SourceFred Hutchinson Cancer Center·JournalJNCI Journal of the National Cancer Institute·DateJul 10, 2013
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GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A study published in JAMA found that daily soy protein supplementation for two years did not reduce or delay the development of biochemical recurrence of prostate cancer. In fact, the supplement may even accelerate the onset of recurrence by a few weeks.
Researchers found that most men report little shared decision making in PSA screening, with only 8% reporting full shared decision making. Coupling physician education with patient activation improves rates of shared decision making and influences physicians' attitudes about screening.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateJul 8, 2013
A Johns Hopkins study of over 1,800 men aged 52-62 suggests that African-Americans with very-low-risk prostate cancers are more likely to have aggressive disease. The study found a higher rate of Gleason score upgrading and organ-confined cancers among black men, highlighting the need for race-specific surveillance entry criteria.
SourceJohns Hopkins Medicine·JournalJournal of Clinical Oncology·DateJun 25, 2013
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Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Use of advanced treatment technologies like IMRT and robotic prostatectomy has increased among men with low-risk disease, despite clinical guidelines recommending local treatment for those with a low life expectancy. The authors suggest that aggressive direct-to-consumer marketing and incentives may promote the use of these treatments.
Researchers have identified genetic variants that can predict aggressive prostate cancers, enabling better treatment options for patients. The study's findings suggest a novel relationship between angiogenesis genes and prostate cancer aggressiveness.
SourceH. Lee Moffitt Cancer Center & Research Institute·JournalPLOS ONE·DateJun 19, 2013
A new study by The Endocrine Society finds that early exposure to BPA significantly increases the risk of both prostate cancer and a precancerous condition known as prostate epithelial neoplasia. The study used human prostate stem cells from organ donors to grow prostate tissue in a mouse model.
A new study by University of Illinois Chicago researcher Gail Prins found that early exposure to BPA in the developing prostate increases the risk of later prostate cancer. Prostate stem cells become sensitized to estrogen through BPA exposure, making them more susceptible to cancer development.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A new drug called pyrvinium pamoate inhibits aggressive prostate cancer resistant to standard drugs by binding to a different site on the AR and inhibiting its activity without preventing androgen binding. This unique mechanism of action has the potential to treat cancers resistant to currently approved therapies.
A study by Dana-Farber Cancer Institute researchers found that active surveillance and watchful waiting are safe alternatives to initial treatment for men with low-risk prostate cancers. These strategies can lead to better quality of life and reduced healthcare costs, with some patients experiencing up to 13 months additional quality-a...
SourceDana-Farber Cancer Institute·JournalAnnals of Internal Medicine·DateJun 17, 2013
Researchers discovered a molecular switch, Steroidogenic Factor 1, that stimulates steroid hormone production and cell multiplication in aggressive prostate cancers. This factor increases tumor growth and resistance to hormone treatment.
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Replacing carbohydrates with vegetable fat may be associated with a lower risk of death in men with nonmetastatic prostate cancer, according to a study published in JAMA Internal Medicine. The study found that men who consumed more vegetable fat had a lower risk of lethal prostate cancer and all-cause mortality.
SourceJAMA Network·JournalJAMA Internal Medicine·DateJun 10, 2013
A new biodegradable implant has shown potential to significantly reduce rectal injury in prostate cancer patients undergoing radiation therapy. The BioProtect Balloon Implant increased the space between the prostate and rectum, reducing radiation exposure by an average of 30%.
SourceVirginia Commonwealth University·JournalJournal of Radiation Oncology·DateJun 10, 2013
A UC San Francisco-led study found that men with non-metastatic prostate cancer who consumed more healthy vegetable fats had a lower risk of developing lethal prostate cancer and dying from other causes. Replacing 10% of daily calories with these fats was associated with a 29% lower risk of lethal prostate cancer.
SourceUniversity of California - San Francisco·JournalJAMA Internal Medicine·DateJun 10, 2013
A new hybrid molecular imaging system combines positron emission tomography and magnetic resonance to detect recurrent prostate cancer. The study reveals that PET/MR finds more areas of metastases than PET/CT, making it a viable alternative for restaging patients with metastatic prostate cancer.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJun 10, 2013
Researchers have developed a novel imaging agent, Tc-99m MIP-1404, which binds to PSMA enzyme in prostate cancer cells, enabling detection of metastases. The agent shows promise in detecting lesions more accurately than standard bone imaging.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJun 10, 2013
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Scientists use antigen-decorated nanoparticles to prevent immune over-reaction in mice, while also developing a potential gene therapy for Mucopolysaccharidosis Type IIIA. Meanwhile, researchers discover a new target for castration-resistant prostate cancer by blocking mutant androgen receptors.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 3, 2013
Researchers at Monash University have identified a sub-group of cells that can contribute to prostate cancer recurrence, opening up new treatment options. These previously unidentified cells are potential targets for future therapies and may be targeted before the cancer reaches an incurable stage.
SourceMonash University·JournalScience Translational Medicine·DateMay 29, 2013
Researchers developed a novel class of peptidomimetic drugs that interrupt androgen receptor signaling in prostate cancer cells, preventing growth. The agents show promise as a potential therapeutic approach for men with advanced disease.
SourceUT Southwestern Medical Center·JournalNature Communications·DateMay 28, 2013
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers have developed a device that captures and isolates potentially high-risk cancer cells, enabling doctors to access and identify cancerous cells in the bloodstream. This technology may revolutionize conventional biopsy practices and significantly advance personalized medicine.
SourceCedars-Sinai Medical Center·JournalAdvanced Materials·DateMay 28, 2013
A novel small molecule has been developed to block the function of androgen receptors, which promote prostate cancer growth. The compound prevents cancer cells from recruiting protein partners and blocks their growth, showing promise for treating prostate cancer.
SourceUniversity of Texas at Dallas·JournalNature Communications·DateMay 28, 2013
A recent study published in Cancer found that African American men with prostate cancer face longer treatment delays than their Caucasian counterparts. The analysis of SEER-Medicare registry data revealed an average delay of 7 days for African American patients, compared to 4 days for Caucasians. Additionally, African Americans were mo...
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers used next-generation sequencing to analyze DNA alterations in adjacent Gleason patterns of the same tumor. The study found that some aggressive prostate cancers have identical genetic markers, enabling better prediction of cancer progression and management.
Researchers have created a low-cost and accurate method for detecting prostate cancer in urine, potentially leading to early diagnosis and improved treatment outcomes. The technology uses nanoscale protein receptors to capture cancer molecule signals, offering a promising alternative to existing tests that can be costly and invasive.
SourceUniversity of California - Irvine·JournalJournal of the American Chemical Society·DateMay 21, 2013
A recent study published in JAMA Internal Medicine found that intensity-modulated radiation therapy (IMRT) may not be more effective than conformal radiation therapy (CRT) after prostatectomy. The study compared outcomes of 457 IMRT and 557 CRT patients treated between 2002 and 2007, showing no significant difference in long-term side ...
SourceUniversity of North Carolina Health Care·JournalJAMA Internal Medicine·DateMay 20, 2013
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Studies of newly diagnosed prostate cancer patients reveal that older, sicker men are unlikely to benefit from aggressive therapy. Researchers found that those aged 61-74 and over 75 with multiple health issues face high risks of mortality from non-prostate causes, suggesting a shift towards more conservative treatment approaches.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateMay 20, 2013
A 14-year study found older men with multiple health issues were at higher risk of dying from other causes, making watchful waiting a viable option for low- to intermediate-risk prostate cancer patients.
SourceUniversity of California - Los Angeles Health Sciences·JournalAnnals of Internal Medicine·DateMay 20, 2013
A new UCI study found that assessing comorbidities can help target prostate cancer patients who may not benefit from a biopsy, potentially reducing unnecessary procedures. The study identified 20% of men as high-risk due to existing health conditions, suggesting alternative care options.
SourceUniversity of California - Irvine·JournalCancer·DateMay 14, 2013
A new study found that bone mineral density testing is not routine among men receiving androgen deprivation therapy, but those with primary care physicians are more likely to receive the test. This highlights the importance of primary care physicians in bone care for men with prostate cancer.
SourceSpringer·JournalJournal of General Internal Medicine·DateMay 14, 2013
A new analysis found a significant link between Agent Orange exposure and high-grade prostate cancer among US Veterans. Exposure to the herbicide was associated with a 52% increase in overall risk of prostate cancer detection by biopsy, as well as a 75% increase in risk of high-grade prostate cancer.
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A new genomic test helps identify low-risk men suitable for active surveillance, sparing them from unnecessary treatment. The test provides statistically significant and clinically meaningful prognostic information, aiding in determining which men are best suited for active surveillance.
SourceUniversity of California - San Francisco·DateMay 8, 2013
Researchers found that combining tomato and soy foods reduced prostate cancer incidence by 55% compared to eating either food alone. The study suggested that consuming three to four servings of tomato products per week and one to two servings of soy foods daily could help protect against prostate cancer.
SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalCancer Prevention Research·DateMay 8, 2013
A study by Thomas Jefferson University researchers found that amplification of the Stat5 gene in prostate cancer cells leads to excess oncogenic protein, driving cancer spread. Gene amplification and protein levels increased with metastasis and castration therapy resistance.
SourceThomas Jefferson University·JournalAmerican Journal Of Pathology·DateMay 7, 2013
The new guideline provides detailed direction on treatment options for prostate cancer patients, including adjuvant and salvage radiotherapy recommendations. It emphasizes the importance of informed consent and patient education on potential side effects and benefits of radiation therapy.
SourceAmerican Society for Radiation Oncology·JournalInternational Journal of Radiation Oncology*Biology*Physics·DateMay 7, 2013
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A recent study by Henry Ford Health reveals that prostate cancer patients with metastasis are more likely to die after weekend emergency department visits compared to weekdays. The study found that these patients have a 23% increased likelihood of death after weekend visits, despite being older and healthier on average.
A new study reveals that surgical volume significantly affects the outcome of procedures, especially for robotic-assisted surgeries. High-volume hospitals demonstrated superior results in terms of complication rates and blood transfusions, while low-volume centers struggled with inferior outcomes.
Researchers found that men with prostate cancer who take statin drugs are significantly less likely to die from their cancer. The study, led by Janet L. Stanford, Ph.D., followed over 1,000 Seattle-area prostate cancer patients for almost eight years and found a 5% mortality rate among statin users versus 1% for nonusers.
SourceFred Hutchinson Cancer Center·JournalThe Prostate·DateMay 1, 2013
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A new study reveals that prostate cancer develops through periodic bursts of genetic mutations, causing complex DNA reshuffling. This process, dubbed 'punctuated cancer evolution,' may lead to more accurate diagnosis and effective treatment in the future.
A new study from Northwestern University suggests that personalized PSA testing can help reduce the number of men who undergo unnecessary biopsies. Genetic correction of PSA levels using genetic variants has been shown to change the outcome for 17 men, and could potentially prevent 15-20% of prostate biopsies annually.
SourceNorthwestern University·JournalThe Journal of Urology·DateApr 24, 2013
Researchers found obese men were more likely to have precancerous lesions detected in their benign prostate biopsies compared to non-obese men. Obesity was also associated with a significantly higher risk of developing prostate cancer after an initial benign biopsy, particularly in the first few years after.
SourceColumbia University's Mailman School of Public Health·DateApr 23, 2013
Research found that specific DNA regions contribute to prostate cancer development and early death, with patients having two of these changes at high risk. The study identifies key genes PTEN and MYC as linked to prostate cancer lethality.
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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.