Articles tagged with Psychiatric Disorders
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A new study by researchers at the University of Birmingham has identified two distinct brain structure patterns associated with poor outcomes in patients with recent onset psychosis and depression. The study used MRI scans to analyze grey matter volume and found that lower volumes were linked to poorer outcomes, while higher volumes we...
A new paper by an Oregon State University-led research team provides a scientific framework to shape the rollout of a program in Oregon allowing the use of psilocybin for therapeutic reasons. The research highlights the importance of Indigenous traditions and safety guidelines for using psilocybin-containing fungi.
The BrainChart platform benchmarks brain development based on MRI data from over 100,000 individuals, creating a standardized chart like those for height and weight. The tool identifies previously unreported neurodevelopmental milestones and provides a common language to understand brain images from different sources.
A study on women-only Alcoholics Anonymous meetings in Brazil found that participants experienced rejection and loneliness due to social stigma. The women-only format provided a safe space for self-expression and reclaimed dignity, differing from mixed meetings where men-focused testimonials prevailed.
A study published in Nutrients found distinct bacteria and metabolomes associated with each personality trait, including mental energy and physical fatigue. The research team discovered unique gut bacteria profiles for different energy and fatigue traits.
A recent Sri Lankan twin study reveals that genetic factors contribute to approximately one-third of the variation in depressive symptoms, while environmental influences account for around two-thirds. The study also found a strong association between depressive symptoms and health-related quality of life.
A systematic review of animal studies suggests that regular caffeine consumption can increase attention and retention capacity in people with ADHD. The study found improved concentration, learning benefits, and memory improvements without adverse effects on blood pressure or body weight.
A new study found that integrating behavioral health into pediatric primary care at federally qualified health centers increases access, timeliness of care, and diagnostic rates of ADHD among diverse children. The model resulted in higher follow-up rates with behavioral health clinicians and reduced polypharmacy.
Mayo Clinic researchers propose a novel computational model that links Alzheimer's disease symptoms to brain anatomy, revealing a complex relationship between mental processing and brain function. The model uses machine learning to analyze patient brain imaging data and compresses complex brain anatomy into a conceptual framework.
A recent brain imaging study has found evidence of weakening connections between key brain areas in adolescents at high genetic risk of developing bipolar disorder. This study suggests that early intervention strategies may be effective in preventing the progression towards major changes in the brain.
Researchers report promising results from a phase 3 clinical trial of MDMA-assisted therapy for post-traumatic stress disorder (PTSD), with two-thirds of participants no longer meeting the diagnostic criteria. The therapy showed better effect sizes than selective serotonin reuptake inhibitors (SSRIs) and was equally effective in treatm...
This cross-sectional study investigated the association between adverse childhood experiences and poor neuropsychiatric health in former NFL players. Football-related concussions were found to be significantly associated with increased risk of dementia and poor neuropsychiatric health among these athletes.
According to a systematic review of over 16 million young people from 25 countries, children with disabilities experience higher rates of violence, including physical, sexual, and emotional abuse. The study highlights the urgent need for collaborative efforts to raise awareness and strengthen prevention efforts.
A recent study found that stimulating reactive astrocytes promotes the elimination of toxic protein aggregates in Huntington's disease. This cooperative mechanism between neurons and astrocytes holds promise for potential treatments.
Brainwide association studies need thousands of individuals to yield higher reproducibility, as smaller samples often uncover strong but spurious associations. Larger sample sizes lead to more likely reproductions of correlations, with effect sizes decreasing as the number of participants increases.
A recent study published in JAMA Psychiatry has found that individuals without jobs or stable housing experience worse depression symptoms when treated with therapy or antidepressants. The researchers analyzed data from nine studies involving over 4,800 participants and discovered that unemployed patients had 28% poorer outcomes compar...
A study found that intact astrocyte networks are essential for neural homeostasis, synaptic plasticity, and spatial cognitive abilities in adult mice. Disrupting these networks impairs spatial learning and memory due to altered neuronal excitability and compromised synaptic transmission.
The Bárány Society has developed a comprehensive curriculum to promote high-quality vestibular training for healthcare professionals. The curriculum sets out a framework of suggested topics and skills, covering anatomy, physiology, and physics, as well as history taking, bedside examination, ancillary testing, disorders, treatment, and...
Children's mental health-related emergency department visits declined by 25.5% during the early COVID-19 pandemic. Visits among vulnerable populations, such as those with intellectual disabilities and childhood-onset disorders, were particularly reduced.
Researchers found a significant association between mental disorders and dementia in a 30-year New Zealand study involving 1.7 million citizens. The study suggests that individuals with mental health conditions may be at higher risk of developing dementia, highlighting the importance of mental health care in preventing cognitive decline.
A new review of theoretical models used to assess and treat mental health issues highlights the vast array of approaches. The lack of clear criteria poses significant implications for diagnosis, assessment, and support.
Researchers found lower functional connectivity between brain areas involved in social and emotional processing in individuals at risk of developing alcohol use disorder. This impairment may affect their ability to interpret facial expressions and respond to their environment, increasing the likelihood of disordered drinking.
The February issues of The American Journal of Psychiatry and Psychiatric Services highlight new research on the opioid crisis, with a focus on improving treatment outcomes. Additionally, the latest issue of Focus features articles on novel neurotherapeutics and practice guidelines for peer specialists and supervisors.
A study found a link between ASMR and higher levels of neuroticism and anxiety. Those who experience ASMR reported reduced anxiety after watching an ASMR video, suggesting it could be a suitable intervention for anxious individuals.
Researchers at Children's Hospital of Philadelphia used deep learning to analyze whole genome sequencing data from African American patients with mental disorders. The model demonstrated over 70% accuracy in distinguishing between disorders and identifying multiple disorders.
Breakthrough research reveals Tuberous Sclerosis Complex arises from human-specific progenitor cells, explaining its pathology. Human-derived cerebral organoid models shed light on complex brain development and potential mechanisms for other diseases.
A team of scientists from Pusan National University conducted an updated meta-analysis to clarify the relationship between alcohol consumption and unprovoked seizures and epilepsy. They found that overall, alcohol drinkers were at a significantly higher risk of developing epilepsy compared to non-drinkers.
A study by USF Genomics program found that prenatal exposure to the Rwandan genocide was associated with epigenetic modifications in genes linked to mental disorders. These 'chemical' changes can have a rapid response to trauma across generations, suggesting a possible link between historical trauma and modern-day mental health issues.
Researchers have discovered a new biomarker, microstate D, associated with increased sleep disturbance and inattention symptoms in adults with ADHD. The study, published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, provides evidence for a more precise diagnosis of the disorder.
A large observational study found that children conceived through assisted reproductive techniques (ART) have generally good mental health throughout adolescence and young adulthood. However, those born after ART had a slightly elevated risk of obsessive-compulsive disorder, which was explained by parental background factors.
A US survey found that dog owners experienced fewer negative psychological impacts from the COVID-19 pandemic compared to potential dog owners. The study suggests that dog ownership may have played a role in mitigating the mental health effects of isolation and confinement.
A study published in PNAS found that individuals with severe schizophrenia have a higher number of rare mutations than those with typical forms of the illness. This discovery could lead to more precise treatments for this chronic disease, which affects over 3 million Americans.
Researchers found alarmingly high attendance rates at hospital emergency departments for children, teens, and adult victims of child abuse and neglect. Children exposed to child maltreatment have substantially increased risk of attending emergency departments during childhood and early adulthood.
Researchers at Cold Spring Harbor Laboratory identified a group of neurons in the mouse brain that regulates motivation and prevents addiction. Increasing activity of these neurons enhances task performance, but not to the point of addiction.
People with schizophrenia struggle to regulate their emotions as negative feelings intensify, unlike healthy individuals who employ coping strategies at higher emotional states. Researchers found that those with schizophrenia tend to be less likely to engage in emotion regulation efforts when emotions are extremely high.
A new study from the University of the Basque Country found that social interaction and contact with family members have a significant positive impact on homeless people's perception of their health. Conversely, longer periods of homelessness and reduced social connections are associated with poorer health perceptions.
A new study found a dramatic increase in people with co-occurring mental health needs and substance use disorders in B.C. prisons, reaching 75% of the prison population. The study calls for more treatment and efforts to address social and structural inequities.
Researchers discovered that eliminating α-endosulfine (ENSA) or blocking its function reduces brain changes and improves memory in mice. ENSA blocks a potassium channel, which, when blocked, combats excess ENSA levels associated with Alzheimer's disease.
Forced family separation on the US-Mexico border led to a high incidence of PTSD, depressive, and anxiety disorders in asylum-seeking children and parents. Reunification did not alleviate these symptoms, highlighting the need for continued support and intervention.
A recent study reveals that child maltreatment is associated with altered oxytocin gene methylation, leading to atypical brain structures and function. This finding suggests a potential biological mechanism for targeting during adolescence to improve the lives of victims of childhood abuse.
Children of depressed parents are more likely to develop depression and poor academic performance, according to a new study published in PLOS ONE. The study found that both maternal and paternal depression have significant effects on children's mental health and educational outcomes.
Researchers developed a method to image lithium in living cells, finding that neurons from bipolar disorder patients accumulate higher levels of lithium than healthy controls. This new tool could help optimize lithium dosage and improve treatment outcomes for patients with bipolar disorder.
Researchers at Mount Sinai found that people used forward thinking when trying to influence others, regardless of controllability. This neural activity was linked to the ventromedial prefrontal cortex, a decision-making center involved in strategic thinking.
A five-year follow-up study found that alexithymia levels decrease significantly from adolescence to young adulthood. Consistency of alexithymia is associated with symptoms of depression and dissociation, while age-related decline in externally oriented thinking is also notable.
Researchers have identified that moment-to-moment brain signal variability can reliably predict the effectiveness of cognitive behavioural therapy for patients with social anxiety disorder. This finding suggests that neural variability may be a reliable indicator of individual differences in treatment response, particularly when using ...
New research highlights the potential of telehealth to increase patient engagement through improved access and convenience. However, studies found limited evidence that telehealth results in better retention or outcomes compared to in-person treatment. Researchers emphasize the need for more empirical work to confirm its benefits.
A recent study published in PLOS Medicine found that people with mental illnesses have poorer sleep quality compared to the general population. The study analyzed data from 89,205 participants and discovered significant differences in sleep patterns, including increased waking frequency and duration.
Researchers found that an existing drug, prucalopride, can improve cognitive function by enhancing activity in brain areas related to memory. In a study of 44 healthy volunteers, those taking prucalopride performed better on a memory test and showed increased activity in the hippocampus and right angular gyrus.
A study of over 29,000 American women found that breastfeeding significantly reduces the risk of postpartum depression. Women who breastfed for longer periods had lower rates of postpartum depression, with those breastfeeding for 6-12 months showing the greatest reduction.
A new study by UCL researchers has found that staying on long-term antidepressants reduces the risk of relapse by 39% compared to those who stop taking them. The study involved 478 primary care patients and found that 56% experienced a relapse within a year if they discontinued their medication, while only 26% did so after a full year.
A new study found that nearly three in ten people with type 2 diabetes in Scotland were prescribed antidepressants before their diagnosis. Additionally, one in ten individuals received antipsychotic prescriptions prior to T2D diagnosis. These findings suggest a link between mental health and the development of type 2 diabetes.
A new study in mice reveals that fragile X treatment can incur resistance, but also identifies potential strategies to overcome this. Administering mGluR5 inhibitors at a young age and then stopping may produce lasting benefits in cognitive ability.
A study published in Communications Biology reveals that chronic hyperglycemia in diabetes impairs working memory performance by altering the connection between key brain regions. Researchers found that areas critical for forming and retrieving memories were over-connected, leading to errors in remembering correct information.
The number of autism diagnoses in England has skyrocketed by 787% over the past two decades, driven primarily by increased recognition and improved diagnosis for females. Researchers analyzed GP records and found that the greatest rises were among adults, with females making up most of the increase.
A multi-site, multi-disorder resting-state magnetic resonance image database was compiled to harmonize data from patients with various diseases, measured at 14 sites. The dataset comprises over 2,400 samples and includes 'traveling-subject' data to minimize inter-site differences.
A recent study reveals that colleges struggle to provide adequate mental health support to Asian and Latino students due to interdependent cultural values and shame. The study suggests that culturally tailored treatment services addressing these issues can improve help-seeking behaviors.
Researchers conducted a new trial to adapt Dialectical Behaviour Therapy (DPT) for people with frequent Bipolar mood swings. The study aimed to evaluate the feasibility and acceptability of this adapted therapy, finding that it has demand from individuals with Bipolar disorder.
A review and meta-analysis investigated the association between mental health disorders and COVID-19-related death. The study found that patients with pre-existing mental health conditions are at a higher risk of dying from COVID-19.
A new study found that 28.4% of adults with a history of suicide attempts are psychologically flourishing, achieving excellent mental health with factors like social support, higher income, and absence of chronic pain contributing to their well-being
Using accurate language to describe mental illness and substance use disorders can help reduce stigma, improving treatment outcomes. The NIH highlights the importance of changing language to mobilize resources toward mental health services and erase prejudices that prevent people from seeking care.