Articles tagged with Psychiatric Disorders
A large-scale animal study reveals that brain pH and lactate levels are a common feature across various neuropsychiatric conditions, including schizophrenia, bipolar disorder, autism, depression, epilepsy, and Alzheimer's disease. Changes in brain energy metabolism are linked to cognitive impairment, particularly working memory.
A new series of essays explores the ethics and social issues raised by brain research, including post-trial obligations for human participants in neural-device trials. The studies reveal that injury and illness rob individuals of personal identity, while neuromodulation can restore it.
A new study published in PLOS Medicine found that individuals with lower income or education levels are more likely to develop medical conditions related to alcohol abuse. The research suggests that these groups may benefit from additional screening by clinicians to evaluate their alcohol consumption and identify related conditions.
Researchers at the University of Texas at Arlington have developed a method to determine the clinical potency of psilocybin and psilocin in Psilocybe cubensis mushrooms. This technique uses liquid chromatography with tandem mass spectrometry, allowing for accurate extraction and measurement of the strength of the mushrooms.
A Duke University-led study suggests that targeting disadvantaged neighborhoods for dementia prevention programs could help lower dementia risk. People living in poorer neighborhoods show early signs of cognitive decline and have measurably poorer brain health as early as age 45, regardless of their own personal income or education.
A new study finds that Latinx children with unreliable access to food at age 4 are nearly four times more likely to develop fatty liver disease later. The researchers recommend earlier screening for metabolic dysfunction-associated steatotic liver disease (MASLD) and ensuring public meal programs offer nutritious meals.
A study analyzing nationally representative data found that youth experienced a sustained increase in mental health issues between 2006 and 2019. The findings suggest that treatment and prevention strategies must address preexisting psychiatric needs in addition to the pandemic's direct effects.
A new study from Karolinska Institutet has found a clear link between childhood adversity and the risk of mental illness later in life. The research suggests that genetics and environment play a significant role in contributing to adult psychiatric disorders, highlighting the need for targeted health care interventions within families ...
A study by SLU professor SangNam Ahn found that childhood and adult adversity can increase the risk of mental illness and cognitive decline later in life. The research team analyzed data from over 3,500 individuals and discovered a strong correlation between adverse events and anxiety, depression, and cognitive impairment.
Scientists have discovered that the bat brainstem processes echolocation and communication calls differently, with a stronger response to less frequent calls due to better neural synchronization. The findings may also be relevant to medical applications in humans, such as understanding diseases like ADHD or schizophrenia.
Delta opioid receptors play a crucial role in anxiety development, and research reveals its therapeutic effects in animal models. KNT-127, a DOP agonist, reduces anxiety-like behavior by suppressing glutamatergic transmission, offering new potential for treating anxiety disorders.
A study of 1,948 U.S. adults with lifetime suicide attempts found that nearly 20% had no prior psychiatric diagnosis, raising questions about suicide risk screening limits. This finding suggests a broader population is at risk and warrants further investigation into suicidal behavior.
Frequent consumption of ultra-processed foods in the US diet is associated with increased rates of colorectal cancer and other gastrointestinal diseases. This may be attributed to additives such as emulsifiers that can disrupt the balance of gut microbiota, leading to disease promotion.
A new blood test uses the biomarker BD-tau to predict functional outcomes in patients after ischemic stroke. Higher levels of BD-tau are associated with more severe outcomes.
A new study published by a University of Waterloo researcher suggests that specific parenting behaviors, such as guiding verbal and physical cues, can help break down pathways leading to ADHD symptoms. Early targeted intervention is crucial in predicting the development of ADHD symptoms in children with exuberant temperament.
A recent study published in JAMA Network Open found that familiar scents can strengthen memory recall in depressed individuals, potentially aiding recovery. Researchers discovered that odors engage the amygdala, a key component of memory formation, more effectively than words.
A study published in The Lancet reveals that Black women in the US are murdered at rates 6 times higher than white women, with gun deaths also disproportionately affecting them. The findings highlight the urgent need to address structural racism and inequities in homicide trends.
A recent study at the University of Eastern Finland gathered information on psychotherapy-associated adverse events, their content and scope. The researchers found no significant negative outcomes in included studies, but highlighted the need for standardised methods to assess adverse effects.
Researchers found that parents' manifestation of neurodevelopmental and psychiatric traits can predict the prevalence and severity of disorders in children. The study analyzed 97,000 families and revealed a correlation between parental traits, suggesting that assortative mating may contribute to increased disease severity.
A high prevalence of mental disorders was found to affect over 1 in 10 individuals aged 5-24 worldwide, with around one-fifth of all disease-related disability attributed to these conditions. This age group accounts for nearly a quarter of the global mental disorder burden across the entire life course.
A study published by Geisinger College faculty and graduate students found that 55% of DSM-5-TR panel members received payments from industry, highlighting the need for stricter standards. The researchers argue that individuals with financial ties to industry should not have decision-making authority in guideline development.
Rates of fatal motor vehicle accidents were highest among military members immediately following their return from deployment, while the highest rates of fatal accidental overdose deaths occurred later in postdeployment life. Younger soldiers between 18-24 years old were at highest risk for MVA and accidental overdoses.
A recent study by University of Missouri researcher Mansoo Yu found that online weight loss interventions with counseling and social support are effective for middle-aged adults with obesity. The study identified two key features: professional health coaching and access to social support from other users, which led to significant long-...
A new study found that propranolol, a medication for high blood pressure, can lower anxiety levels in individuals with autism spectrum disorder. The study involved 69 patients and showed significantly reduced anxiety levels compared to a placebo group.
Researchers found that 94% of patients with posterior cortical atrophy had Alzheimer's pathology, while only 70% of those with memory loss did. Early identification of PCA may lead to better treatment options for Alzheimer's patients.
The $20 million SOAR study aims to identify key risk and resiliency factors affecting behavioral health. The research will inform strategies to improve treatment options and patient outcomes in the state of Ohio.
A new study found that Black and Hispanic patients were less likely to be restrained in an emergency department compared to White patients. However, female Black and Hispanic patients with mental illness or substance use disorder were more likely to receive restraints than male counterparts.
Research from the University of Cambridge found that people with overweight or obesity experience a short-term increase in bodyweight when their depressive symptoms rise. The study suggests that monitoring and addressing depressive symptoms could help prevent further weight gain and improve overall health.
Female high-school students with sub-threshold ADHD and autism traits experience worsened mood swings, irritability, bloating, and fatigue before menstruation. These findings highlight the need for better support systems to address PMDD's impact on school adjustment, performance, and relationships.
A nationwide case-time-control study found an association between benzodiazepine use during pregnancy and an increased risk of miscarriage. The results suggest that healthcare professionals should carefully weigh the benefits and risks of using benzodiazepines to treat psychiatric and sleep disorders in pregnant women.
A study of 70 autistic youths in psychiatric hospitals found wearable biosensing and machine learning can identify impending aggressive behaviors. The findings suggest a potential for developing adaptive intervention systems to prevent aggression.
Researchers at the University of Cincinnati's Lindner Center of HOPE have developed a novel approach to treating depression using spinal cord stimulation. The study found that electrical stimulation of the spinal cord decreased depressive symptoms and showed therapeutic potential.
A new University of Maryland School of Medicine review article published in the New England Journal of Medicine finds nearly 16 million Americans have cannabis use disorder, with young adults disproportionately affected. The review emphasizes the need for doctors to screen and treat patients experiencing symptoms of cannabis use disorder.
A new study has found that the QbTest, a widely used computerized test for Attention-deficit/hyperactivity disorder (ADHD), is not accurate enough to be used as a standalone diagnostic tool. The researchers emphasize that the QbTest should be used in conjunction with clinical assessment and judgment to arrive at a diagnosis.
Research compares US, Australian, and UK gun violence rates to mental illness rates, finding higher US rates without comparable differences in mental illness prevalence. Gun ownership and access to firearms are suggested as plausible but unproven explanations for the disparity.
A randomized clinical trial found that Mindfulness-Oriented Recovery Enhancement (MORE) plus usual care significantly decreased drug use, pain, and depression in individuals with opioid use disorder and chronic pain. Participants who received MORE also showed increased methadone treatment retention and adherence.
A study of over 50,000 Korean adolescents found that those using smartphones for more than 4 hours a day had higher rates of stress, thoughts of suicide, and substance use. In contrast, lighter users showed no greater health risks compared to non-users.
Researchers used brain imaging and machine learning to identify distinct patterns of brain connectivity in people with autism spectrum disorder (ASD), taking into account individual differences. The study reveals that certain brain features are shared across subtypes, while others are unique to specific individuals.
Researchers have developed new tools to assess disease progression of Alzheimer's disease in animal models, providing a translational approach for studying the disease. The tools use neuroimaging and network modeling techniques to analyze metabolic changes in the brain, confirming previous clinical findings.
The University of Louisville has been awarded $11.5 million from the National Institutes of Health to research and treat eating disorders. The project will investigate how eating disorders develop in childhood and adolescence, their contribution to suicidal behaviors, and the development of innovative personalized treatment.
A recent study published in Annals of Family Medicine explores how technology is changing medical practice, including the use of AI-driven tools to effectively diagnose patients. The study also examines the interplay between fulfillment of basic psychological needs at work and technology use in maintaining clinician well-being.
A two-year study found that participants who received personalized coaching experienced a modest boost in cognitive testing, measuring a 74% improvement over the non-intervention group. Additionally, improvements were noted between the two groups in measurements of risk factors and quality of life.
Researchers at UCSF and Kaiser Permanente Washington found that participants who received personalized coaching experienced a 74% improvement in cognitive testing compared to non-intervention participants. The study also showed improvements in risk factors and quality of life, with modest but significant increases in cognitive function.
Researchers developed a new diagnostic tool to identify and treat Hikikomori, a condition characterized by prolonged physical isolation or social withdrawal. The Hikikomori Diagnostic Evaluation (HiDE) assesses the severity of social withdrawal, providing a practical guide for clinicians.
A new study found that individuals with gambling addiction are at an 89% higher risk of being on long-term sick leave for six years. Those with female gender, less education, and living in less densely populated areas were more likely to experience this risk.
Researchers at the University of Wisconsin-Madison have successfully generated human norepinephrine neurons from stem cells using a key protein called ACTIVIN-A. These LC-NE neurons may serve as models for disease in humans, enabling scientists to screen drugs and answer questions about neurodegeneration.
Rahn Baily, MD, has made significant contributions to the field of psychiatry and healthcare reform through his research on health disparities, violence, and mental illness. He will receive the prestigious Solomon Carter Fuller Award for his outstanding achievements in addressing pressing societal needs.
The COVID-19 pandemic and drug overdose epidemic significantly contributed to the widening gender gap in US life expectancy. Chronic metabolic disease and mental illness are also thought to play a role in the growing disparity.
Experts call for urgent measures to address discrimination against patients fleeing war or conflict zones, those with serious mental illnesses, and frail elderly patients. Guidelines for treating advanced breast cancer should prioritize patient preferences and involve multidisciplinary care teams.
A new study has identified a brain connectivity variate that predicts psychiatric disorders in adolescents. The finding provides evidence for a transdiagnostic brain-based measure underlying individual differences in developing psychiatric disorders in early adolescence.
Researchers at Purdue University have developed noninvasive wearable sensors that can measure uric acid levels in human sweat, offering faster and more accurate diagnosis, therapy, and prognosis for conditions like anxiety and hypertension. The sensors, called EPICS, have higher sensitivity and better wearability than traditional sensors.
Researchers at DZNE and Charité developed a novel treatment for autoimmune encephalitis by reprogramming white blood cells to target misdirected antibodies. The new therapy, called CAAR-T cells, has shown accuracy in laboratory studies and is planned for clinical trials.
Researchers developed a new way to diagnose bipolar disorder using a simple blood test that can identify up to 30% of patients. The test, combined with digital mental health assessments, can differentiate between major depressive disorder and bipolar disorder.
A review of trials comparing ACT and CBT for depression found mixed results, but suggested that traditional CBT may have a slight edge. The research highlights the need for more reliable trial results to inform treatment decisions.
The study, which analyzed data from older adults with peptic ulcer disease, revealed that approximately 1 in 8 individuals developed depression for the first time during the pandemic. Women, those who felt lonely, and those with functional limitations were at higher risk of depression. Targeted screening and intervention are being reco...
A meta-analysis of 40 studies involving 310,000 youths found low treatment rates for depression and anxiety in children and adolescents. Targeted interventions to improve psychiatric disorder treatment rates are urgently required.
A study of 340,000 pregnant women in southern California found a significant association between long-term exposure to antepartum and postpartum air pollution and increased risks of postpartum depression. The findings highlight the importance of identifying modifiable environmental risk factors to improve maternal mental health.
A new trial combining an Alzheimer's medication with two other drugs may amplify its effects and arrest disease progression. The trial, funded by a $150M grant, will recruit 900 participants with early-onset Alzheimer's.
A major European study found that almost all patients with skin diseases face embarrassment, leading to a huge psychological toll. The study also revealed that stigmatization is a major impact of skin diseases on personal and professional life.
Researchers found that antidepressant escitalopram increases synaptic density in the brain over weeks, leading to greater brain plasticity. This explains why effects of antidepressants take time to kick-in, with significant differences in synapse density between treatment and placebo groups.