Articles tagged with Psychiatric Disorders
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A study published in The Lancet reveals that Black women in the US are murdered at rates 6 times higher than white women, with gun deaths also disproportionately affecting them. The findings highlight the urgent need to address structural racism and inequities in homicide trends.
A recent study at the University of Eastern Finland gathered information on psychotherapy-associated adverse events, their content and scope. The researchers found no significant negative outcomes in included studies, but highlighted the need for standardised methods to assess adverse effects.
Researchers found that parents' manifestation of neurodevelopmental and psychiatric traits can predict the prevalence and severity of disorders in children. The study analyzed 97,000 families and revealed a correlation between parental traits, suggesting that assortative mating may contribute to increased disease severity.
A high prevalence of mental disorders was found to affect over 1 in 10 individuals aged 5-24 worldwide, with around one-fifth of all disease-related disability attributed to these conditions. This age group accounts for nearly a quarter of the global mental disorder burden across the entire life course.
A study published by Geisinger College faculty and graduate students found that 55% of DSM-5-TR panel members received payments from industry, highlighting the need for stricter standards. The researchers argue that individuals with financial ties to industry should not have decision-making authority in guideline development.
Rates of fatal motor vehicle accidents were highest among military members immediately following their return from deployment, while the highest rates of fatal accidental overdose deaths occurred later in postdeployment life. Younger soldiers between 18-24 years old were at highest risk for MVA and accidental overdoses.
A recent study by University of Missouri researcher Mansoo Yu found that online weight loss interventions with counseling and social support are effective for middle-aged adults with obesity. The study identified two key features: professional health coaching and access to social support from other users, which led to significant long-...
A new study found that propranolol, a medication for high blood pressure, can lower anxiety levels in individuals with autism spectrum disorder. The study involved 69 patients and showed significantly reduced anxiety levels compared to a placebo group.
Researchers found that 94% of patients with posterior cortical atrophy had Alzheimer's pathology, while only 70% of those with memory loss did. Early identification of PCA may lead to better treatment options for Alzheimer's patients.
The $20 million SOAR study aims to identify key risk and resiliency factors affecting behavioral health. The research will inform strategies to improve treatment options and patient outcomes in the state of Ohio.
A new study found that Black and Hispanic patients were less likely to be restrained in an emergency department compared to White patients. However, female Black and Hispanic patients with mental illness or substance use disorder were more likely to receive restraints than male counterparts.
Research from the University of Cambridge found that people with overweight or obesity experience a short-term increase in bodyweight when their depressive symptoms rise. The study suggests that monitoring and addressing depressive symptoms could help prevent further weight gain and improve overall health.
Female high-school students with sub-threshold ADHD and autism traits experience worsened mood swings, irritability, bloating, and fatigue before menstruation. These findings highlight the need for better support systems to address PMDD's impact on school adjustment, performance, and relationships.
A nationwide case-time-control study found an association between benzodiazepine use during pregnancy and an increased risk of miscarriage. The results suggest that healthcare professionals should carefully weigh the benefits and risks of using benzodiazepines to treat psychiatric and sleep disorders in pregnant women.
A study of 70 autistic youths in psychiatric hospitals found wearable biosensing and machine learning can identify impending aggressive behaviors. The findings suggest a potential for developing adaptive intervention systems to prevent aggression.
Researchers at the University of Cincinnati's Lindner Center of HOPE have developed a novel approach to treating depression using spinal cord stimulation. The study found that electrical stimulation of the spinal cord decreased depressive symptoms and showed therapeutic potential.
A new University of Maryland School of Medicine review article published in the New England Journal of Medicine finds nearly 16 million Americans have cannabis use disorder, with young adults disproportionately affected. The review emphasizes the need for doctors to screen and treat patients experiencing symptoms of cannabis use disorder.
A new study has found that the QbTest, a widely used computerized test for Attention-deficit/hyperactivity disorder (ADHD), is not accurate enough to be used as a standalone diagnostic tool. The researchers emphasize that the QbTest should be used in conjunction with clinical assessment and judgment to arrive at a diagnosis.
Research compares US, Australian, and UK gun violence rates to mental illness rates, finding higher US rates without comparable differences in mental illness prevalence. Gun ownership and access to firearms are suggested as plausible but unproven explanations for the disparity.
A randomized clinical trial found that Mindfulness-Oriented Recovery Enhancement (MORE) plus usual care significantly decreased drug use, pain, and depression in individuals with opioid use disorder and chronic pain. Participants who received MORE also showed increased methadone treatment retention and adherence.
A study of over 50,000 Korean adolescents found that those using smartphones for more than 4 hours a day had higher rates of stress, thoughts of suicide, and substance use. In contrast, lighter users showed no greater health risks compared to non-users.
Researchers used brain imaging and machine learning to identify distinct patterns of brain connectivity in people with autism spectrum disorder (ASD), taking into account individual differences. The study reveals that certain brain features are shared across subtypes, while others are unique to specific individuals.
Researchers have developed new tools to assess disease progression of Alzheimer's disease in animal models, providing a translational approach for studying the disease. The tools use neuroimaging and network modeling techniques to analyze metabolic changes in the brain, confirming previous clinical findings.
The University of Louisville has been awarded $11.5 million from the National Institutes of Health to research and treat eating disorders. The project will investigate how eating disorders develop in childhood and adolescence, their contribution to suicidal behaviors, and the development of innovative personalized treatment.
A recent study published in Annals of Family Medicine explores how technology is changing medical practice, including the use of AI-driven tools to effectively diagnose patients. The study also examines the interplay between fulfillment of basic psychological needs at work and technology use in maintaining clinician well-being.
A two-year study found that participants who received personalized coaching experienced a modest boost in cognitive testing, measuring a 74% improvement over the non-intervention group. Additionally, improvements were noted between the two groups in measurements of risk factors and quality of life.
Researchers at UCSF and Kaiser Permanente Washington found that participants who received personalized coaching experienced a 74% improvement in cognitive testing compared to non-intervention participants. The study also showed improvements in risk factors and quality of life, with modest but significant increases in cognitive function.
Researchers developed a new diagnostic tool to identify and treat Hikikomori, a condition characterized by prolonged physical isolation or social withdrawal. The Hikikomori Diagnostic Evaluation (HiDE) assesses the severity of social withdrawal, providing a practical guide for clinicians.
A new study found that individuals with gambling addiction are at an 89% higher risk of being on long-term sick leave for six years. Those with female gender, less education, and living in less densely populated areas were more likely to experience this risk.
Researchers at the University of Wisconsin-Madison have successfully generated human norepinephrine neurons from stem cells using a key protein called ACTIVIN-A. These LC-NE neurons may serve as models for disease in humans, enabling scientists to screen drugs and answer questions about neurodegeneration.
Rahn Baily, MD, has made significant contributions to the field of psychiatry and healthcare reform through his research on health disparities, violence, and mental illness. He will receive the prestigious Solomon Carter Fuller Award for his outstanding achievements in addressing pressing societal needs.
The COVID-19 pandemic and drug overdose epidemic significantly contributed to the widening gender gap in US life expectancy. Chronic metabolic disease and mental illness are also thought to play a role in the growing disparity.
Experts call for urgent measures to address discrimination against patients fleeing war or conflict zones, those with serious mental illnesses, and frail elderly patients. Guidelines for treating advanced breast cancer should prioritize patient preferences and involve multidisciplinary care teams.
A new study has identified a brain connectivity variate that predicts psychiatric disorders in adolescents. The finding provides evidence for a transdiagnostic brain-based measure underlying individual differences in developing psychiatric disorders in early adolescence.
Researchers at Purdue University have developed noninvasive wearable sensors that can measure uric acid levels in human sweat, offering faster and more accurate diagnosis, therapy, and prognosis for conditions like anxiety and hypertension. The sensors, called EPICS, have higher sensitivity and better wearability than traditional sensors.
Researchers at DZNE and Charité developed a novel treatment for autoimmune encephalitis by reprogramming white blood cells to target misdirected antibodies. The new therapy, called CAAR-T cells, has shown accuracy in laboratory studies and is planned for clinical trials.
Researchers developed a new way to diagnose bipolar disorder using a simple blood test that can identify up to 30% of patients. The test, combined with digital mental health assessments, can differentiate between major depressive disorder and bipolar disorder.
A review of trials comparing ACT and CBT for depression found mixed results, but suggested that traditional CBT may have a slight edge. The research highlights the need for more reliable trial results to inform treatment decisions.
The study, which analyzed data from older adults with peptic ulcer disease, revealed that approximately 1 in 8 individuals developed depression for the first time during the pandemic. Women, those who felt lonely, and those with functional limitations were at higher risk of depression. Targeted screening and intervention are being reco...
A meta-analysis of 40 studies involving 310,000 youths found low treatment rates for depression and anxiety in children and adolescents. Targeted interventions to improve psychiatric disorder treatment rates are urgently required.
A study of 340,000 pregnant women in southern California found a significant association between long-term exposure to antepartum and postpartum air pollution and increased risks of postpartum depression. The findings highlight the importance of identifying modifiable environmental risk factors to improve maternal mental health.
A new trial combining an Alzheimer's medication with two other drugs may amplify its effects and arrest disease progression. The trial, funded by a $150M grant, will recruit 900 participants with early-onset Alzheimer's.
A major European study found that almost all patients with skin diseases face embarrassment, leading to a huge psychological toll. The study also revealed that stigmatization is a major impact of skin diseases on personal and professional life.
Researchers found that antidepressant escitalopram increases synaptic density in the brain over weeks, leading to greater brain plasticity. This explains why effects of antidepressants take time to kick-in, with significant differences in synapse density between treatment and placebo groups.
A Phase IIIb study published in the New England Journal of Medicine found that esketamine nasal spray achieved higher remission rates (27.1%) compared to quetiapine extended-release (17.6%) in patients with treatment-resistant depression, indicating its potential as a targeted therapy for this population.
The ESCAPE-TRD study found that esketamine nasal spray outperforms quetiapine in treating treatment-resistant major depression, with patients showing higher remission rates and reduced depressive symptoms. The results suggest esketamine as a safe and effective treatment option for those with treatment-resistant depression.
A new study reveals that esketamine nasal spray is effective in treating treatment-resistant depression, with 27.1% of patients achieving remission after 8 weeks compared to 17.6% on quetiapine XR. Long-term data shows sustained remission rates at 21.7% for esketamine NS and 14.1% for quetiapine XR.
New research reveals that children with childhood mental health issues are at higher risk of social isolation, low educational attainment, financial difficulties, and heavy substance use in late teens and early 20s. The study also found a strong link between internalising symptoms and poor physical health in young adulthood.
A study reviewing current research on ADHD in older adults highlights the need for better approaches to screening and diagnosis. The authors conclude that existing guidelines focus on children and young adults, leading to a lack of consideration for the condition in people aged 50-55.
The COVID-19 pandemic led to a significant increase in emergency department visits and hospitalizations for self-harm and suicidal ideation among adolescents, particularly young female adolescents. The disruptions of the pandemic may have contributed to this trend.
This exploratory study reveals racial differences in clinical presentation among individuals diagnosed with frontotemporal dementia. The findings suggest that racially minoritized individuals may experience more severe dementia severity, functional impairment, and neuropsychiatric symptoms.
A study published in Brain, Behavior, and Immunity found that inflammation-related genes play a significant role in depression. The researchers discovered correlations between immune-related genes, DNA methylation patterns, and brain structure abnormalities in patients with major depressive disorder.
Researchers at Pitt Public Health analyzed thousands of human genomes to find new gene variations influencing Alzheimer's disease risk. They identified 15 additional variations in the APOE gene and other genome areas that may influence disease risk, although more research is needed for definitive conclusions.
A new blood-based test called p-tau217 has shown great promise in identifying Alzheimer's disease by stratifying patients into low, intermediate, and high-risk groups. The two-step workflow reduces the need for confirmatory testing in uncertain cases.
A study of 1.3 million people found that those with hospital-treated depression have a high risk of developing conditions like bipolar disorder, schizophrenia, and anxiety disorders. Genetic analysis also revealed a link between depression and reduced cognitive abilities, such as abstract thinking and mental flexibility.
A new study found that people who received free produce prescriptions experienced increased fruit and vegetable consumption, leading to improved body mass index, blood sugar, and blood pressure levels. This research suggests that produce prescription programs may be an effective way to address food insecurity and promote health.
A Rutgers-led study found that improving prison reentry programs for highest-risk users can help reduce opioid overdose deaths in the US. Strengthening healthcare services, such as psychiatric medication and syringe services, is crucial to engage individuals in opioid use treatment after release.
Neuroscientists found that adversities permanently alter brain structure and function, increasing the risk of psychiatric disorders. An aberrant reaction to adversities is related to anxiety symptoms, with potential predictive value for disorder development.
A new study found that high-stress caregivers had higher klotho levels and longer telomeres in specific immune cells, which may provide protection against aging. In contrast, low-stress caregivers showed no significant associations between klotho levels and telomere length.
A new study finds that severe behavioral symptoms in older adults are associated with a higher likelihood of divorce, while those with more advanced dementia are less likely to end their marriages. The research analyzed data from 263 married couples and found a positive correlation between neuropsychiatric symptoms and divorce risk.