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Angiotensin inhibitors and receptor blockers linked to lower risk of nonmelanoma skin cancer

Researchers found a significant association between ACE inhibitor and ARB use and reduced incidence of basal cell carcinoma and squamous cell cancers in U.S. veterans. The study revealed a 39% relative reduction in basal cell cancer and 33% relative reduction in squamous cell cancers among users compared to non-users.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateAug 26, 2008
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Researchers discover scent of skin cancer

Researchers at Monell Chemical Senses Center have discovered a unique scent associated with basal cell carcinoma, the most common form of skin cancer. By analyzing volatile organic compounds in the air above skin lesions, they found distinct profiles that could potentially be used to screen for and diagnose skin cancers at early stages.

SourceMonell Chemical Senses Center·JournalBritish Journal of Dermatology·DateAug 20, 2008

JCI online early table of contents: July 10, 2008

A mouse study reveals that sex-specific growth hormone secretion patterns mediate gender-associated differences in susceptibility to diseases caused by inappropriate thrombosis. Additionally, research identifies the protein FGF9 as a key player in prostate cancer progression to osteoblastic bone metastases.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJul 10, 2008
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Sunburn alert: UVB does more damage to DNA than UVA

A new research study published in the FASEB Journal reveals that UVB light is more likely to cause DNA damage and lead to skin cancer than UVA light. This finding has significant implications for public health officials and government regulatory agencies, who can now use this information to develop more effective sunscreen products.

SourceFederation of American Societies for Experimental Biology·JournalThe FASEB Journal·DateJul 1, 2008

Skin flaps deliver cancer-fighting therapy, ASPS study reveals

A new delivery technique using skin flaps and gene therapy reduces tumor volume by 79% in rats. The treatment allows for the production of therapeutic proteins directly at the tumor site, avoiding liver damage caused by traditional intravenous administration.

SourceAmerican Society of Plastic Surgeons·JournalPlastic & Reconstructive Surgery·DateMay 8, 2008

A study reveals how cells communicate to activate the cell division machinery

A study published in the EMBO Journal reveals that distinct signaling pathways between neighboring cells regulate cell division. Notch and Wnt/Wingless pathways control proliferation through gene effectors dMyc and bantam, which instruct E2F to activate the cell division machinery.

SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalThe EMBO Journal·DateMay 5, 2008
Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Saving cancer patients' skin

A new breed of targeted cancer drugs is attacking specific proteins in cancer cells, but also causes devastating dermatologic side effects. The Cancer Skin Care Program at Northwestern University provides specially formulated lotions and drugs to help patients preserve their dignity and quality of life.

SourceNorthwestern University·DateMar 27, 2008

Study shows effects of vitamin D and skin's physiology

Researchers from Boston University School of Medicine found that previtamin D3 production varies depending on skin type and weather conditions. Vitamin D deficiency is common worldwide, with increased risk of cancers and autoimmune diseases associated with higher altitudes.

SourceBoston University·JournalJournal of Bone and Mineral Research·DateFeb 20, 2008

Robotic device appears useful for surgical removal of cancer involving the tonsils

A new robotic surgery technique called transoral robotic surgery (TORS) has been shown to be effective in removing tonsil cancer with minimal complications and improved patient outcomes. In a study of 27 patients, surgeons successfully removed all cancerous tissues in 93% of cases, with an average surgery time of one hour and 43 minutes.

SourceJAMA Network·JournalArchives of Otolaryngology - Head and Neck Surgery·DateDec 17, 2007
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

JCI table of contents: Dec. 3, 2007

A new study published in JCI Journal has found that CP-31398, a compound that binds to mutant forms of the p53 protein, can prevent and treat UV light–induced skin cancers in mice. The study also demonstrated that CP-31398 increased p53 function in human skin cancer cells expressing a mutant form of p53.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 3, 2007

Promising approach to a more effective sunscreen

Researchers discovered a promising new agent, CP-31398, that restores mutant p53 tumor suppressor function and inhibits skin cancer growth in mice exposed to UVB light. The findings suggest potential for this approach as a sunscreen component for preventing and treating UV light-induced skin cancers.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 3, 2007

3-D model of esophageal cancer

A team of scientists has developed a tissue-engineered, organotypic 3D culture system of esophageal squamous cell cancer, revealing the genetic mutations and tumor microenvironment driving the disease. The model also highlights the critical role of stromal fibroblasts in cancer progression.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateOct 31, 2007
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Broccoli sprout-derived extract protects against ultraviolet radiation

A team of Johns Hopkins scientists found that topical application of broccoli sprout-derived extract can protect human skin against UV radiation-induced damage. The extract works by boosting protective enzymes in cells, providing long-lasting protection even after the extract is removed from the skin.

SourceJohns Hopkins Medicine·JournalProceedings of the National Academy of Sciences·DateOct 22, 2007

Folic acid lowers blood arsenic levels, according to Mailman School of Public Health study

A study published in the American Journal of Clinical Nutrition found that folic acid supplements can dramatically lower blood arsenic levels by up to 14 percent. Folate deficiency is common in Bangladesh, where the study was conducted, and supplementation enhanced detoxification of arsenic.

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Clinical Nutrition·DateOct 8, 2007

UVA researchers explain cell response to skin-damaging UV rays

Researchers at UVA Health System discovered how cells protect themselves from DNA damage caused by UV rays, involving an unexpected connection between proteins. The study reveals part of a pathway inside human cells that regulates when and how cells repair damage to their DNA.

SourceUniversity of Virginia Health System·JournalCell·DateOct 1, 2007

A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols

Researchers have developed a protocol for generating mice with squamous cell carcinoma, allowing them to study the disease in a controlled environment. The method involves injecting mice with DMBA and TPA, leading to tumor formation and enabling scientists to examine the role of the immune system in susceptibility to skin cancer.

SourceCold Spring Harbor Laboratory·JournalCold Spring Harbor Protocols·DateSep 4, 2007
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Natural chemical found in broccoli helps combat skin blistering disease

Researchers have discovered that sulforaphane can prevent severe blistering and skin breakage associated with the rare genetic disease EBS. The study, funded by various organizations, found marked improvement in treated mice, suggesting a potential therapeutic for this condition.

SourceJohns Hopkins Medicine·JournalProceedings of the National Academy of Sciences·DateAug 20, 2007

Caffeine and exercise can team up to prevent skin cancer

A Rutgers study found that moderate caffeine intake combined with exercise can protect against UVB radiation-induced skin damage. Apoptosis rates increased by 95% in caffeine drinkers, 120% in exercisers, and nearly 400% in those who drank and exercised.

SourceRutgers University·JournalProceedings of the National Academy of Sciences·DateJul 30, 2007

Protein protects anti-cancer gene from chemical shutdown

Researchers at the University of Texas M.D. Anderson Cancer Center discovered that a protein called IKK-alpha protects an important cell defense mechanism from silencing in skin cancers. The protein prevents DNA methylation, which normally silences the checkpoint gene 14-3-3-sigma.

SourceUniversity of Texas M. D. Anderson Cancer Center·JournalMolecular Cell·DateJul 19, 2007
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Kaposi sarcoma arises independently from multiple cells

A study published in the Journal of the National Cancer Institute found that nearly 80% of Kaposi sarcoma tumors arose independently from multiple cells. This challenges the traditional understanding of cancer origins, suggesting that Kaposi sarcoma is not a true metastatic cancer.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJul 10, 2007

p53 gene mutations and inflammation trigger skin cancer

Research reveals that p53 gene mutations can trigger skin cancer, particularly squamous cell carcinoma (SCC), by accelerating malignant progression and sensitizing skin cells to tumor formation. Inflammation also plays a critical role in SCC development, with the chemokine receptor D6 acting as a key regulator.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJul 2, 2007

Natural signal holds promise for psoriasis, age-related skin damage

Researchers have discovered a natural body lipid that signals cells to normalize growth and maturation. The finding, published in The Journal of Investigative Dermatology, shows that bypassing the signaling pathway restores normal differentiation of skin cells in diseases like psoriasis.

SourceMedical College of Georgia at Augusta University·JournalJournal of Investigative Dermatology·DateJun 28, 2007

Scientists discover role of enzyme in DNA repair

Researchers found that a specific enzyme, ATM, plays a crucial role in shutting down transcription near sites of DNA damage, ensuring repair in an undisturbed environment. This discovery could lead to a better understanding of genetic aberrations and cancer development in individuals with ATM deficiency.

SourceNIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases·JournalNature·DateJun 27, 2007
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Caspase-14 protects our skin against UVB and dehydration

Researchers discovered that caspase-14 plays a crucial role in maintaining the skin's balance of moisture and protecting against UVB radiation. The protein helps to regulate the processing of a key protein involved in skin structure, which can explain dehydration.

SourceVIB (the Flanders Institute for Biotechnology)·JournalNature Cell Biology·DateMay 21, 2007

Gender linked to development of skin cancer

Researchers at Ohio State University found that male mice developed squamous cell carcinoma tumors earlier and had more aggressive tumors than female mice. The study suggests that gender-linked differences in antioxidants may be the key reason behind this disparity.

SourceOhio State University Wexner Medical Center·JournalCancer Research·DateApr 1, 2007

Chemicals in brown algae may protect against skin cancer

Research suggests that brown algae polyphenols (BAPs) extracted from a marine seaweed can reduce the number of skin tumors by up to 60% and their size by up to 43%. The substances also reduced inflammation, with lower levels of COX-2 and prostaglandin E2 detected in BAP-treated animals.

SourceOhio State University·JournalInternational Journal of Cancer·DateJan 25, 2007
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Tea helps treat damaged skin in cancer patients

Researchers found that tea extracts reduce inflammation and duration of radiation-induced skin damage by up to 10 days. Green tea extracts are more effective than black tea in some patients.

SourceBMC (BioMed Central)·JournalBMC Medicine·DateNov 30, 2006

Firefighters face increased risk for certain cancers

Researchers at the University of Cincinnati found that firefighters are twice as likely to develop testicular cancer and have higher rates of non-Hodgkin's lymphoma and prostate cancer. The study analyzed data from 110,000 firefighters and confirmed previous findings on multiple myeloma risk.

SourceUniversity of Cincinnati·JournalJournal of Occupational and Environmental Medicine·DateNov 10, 2006
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Safer suntans through science

Scientists at the University of Kentucky are testing a lotion that stimulates melanin production, reducing UV damage and increasing skin protection. The treatment has promising results, offering an alternative to traditional sunless tanning products and tanning beds.

SourceUniversity of Kentucky·JournalNature·DateSep 26, 2006

OHSU lab links gene to aged skin problems, cancer

Researchers at OHSU discovered that the over-expression of Smad7 causes epidermal stem cells to shift from producing hair follicles to sebaceous glands in aged skin. This finding provides a potential therapeutic approach for treating hair loss, oily skin, and certain cancers.

SourceOregon Health & Science University·JournalDevelopmental Cell·DateSep 8, 2006

Positive parenting helps encourage healthy sun habits in children

A parent-based intervention program encourages sun-safe behaviors and discourages tanning among children with high-quality relationships between parents and children. Family variables such as compliance and monitoring levels also impact the effectiveness of the program.

SourceJAMA Network·JournalArchives of Dermatology·DateAug 21, 2006
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Pinning down a cancer threesome

Researchers discovered a cancer triad involving Ras, c-myc, and p21 genes. Mice lacking the c-myc gene showed resistance to skin cancer, while mice with both missing genes regained sensitivity to mutated Ras. This study provides new insights into epithelial tumor development.

SourceEcole Polytechnique Fédérale de Lausanne·JournalGenes & Development·DateJul 31, 2006

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor

Researchers have discovered a major gateway for KSHV entry into human cells, suggesting the virus may facilitate its own infectivity by inducing stress responses. This finding has significant implications for understanding Kaposi's sarcoma and developing new treatments.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalScience·DateApr 6, 2006
AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Low vitamin D levels associated with increased total cancer incidence

Researchers found that higher vitamin D levels were associated with a significant reduction in total cancer incidence and mortality, as well as specific types of digestive system cancers. Daily supplementation with at least 1500 IU of vitamin D may be required to optimize benefits on cancer risk.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateApr 4, 2006

Plexxikon advances first oncology development candidate

Plexxikon's V600E B-Raf inhibitor demonstrated robust efficacy in xenograft models using a once-daily low oral dose, showing tumor shrinkage and prolonged delay of tumor growth. The company intends to file an IND application and initiate Phase 1 clinical trials for the oncogenic B-Raf inhibitor.

SourceAB Corporate Communications·DateApr 3, 2006

Researchers link human papillomavirus (HPV) to common skin cancer

A study found an association between HPV antibodies and squamous cell carcinoma risk, with patients diagnosed with squamous cell carcinoma more frequently testing positive for beta type HPVs. Lifestyle habits, such as sun exposure and smoking, were not significantly linked to skin cancer development.

SourceThe Geisel School of Medicine at Dartmouth·JournalJNCI Journal of the National Cancer Institute·DateMar 14, 2006

HPV subtype associated with squamous cell skin cancers

Researchers found a higher frequency of genus beta type HPV antibodies in patients with squamous cell carcinoma (SCC) than control subjects, especially HPV 5. No association was found between HPV and basal cell carcinomas.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateMar 14, 2006

Light-based device probes for early cancer signs

A light-based device probe has been developed to detect early cancer signs in the esophagus, emitting light that scatters when it hits the cell nucleus. The technology could be adapted to detect pre-cancerous cells on any organ's surface, potentially increasing the likelihood of cancer detection.

SourceDuke University·JournalOptics Letters·DateMar 9, 2006
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Ultraviolet B light exposure associated with increased risk of skin cancer

Research found a high number of chromid breaks associated with increased risk of nonmelanoma skin cancers and basal cell carcinomas, while melanoma risk was not linked. UV-B radiation sensitivity also interacted with other risk factors for squamous cell and basal cell carcinomas.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateDec 20, 2005

Cancer prevention news tips

Research suggests that consuming broccoli sprouts daily can improve chronic bacterial gastritis and potentially prevent stomach cancer. The compound sulforaphane in broccoli sprouts also has been shown to have anti-cancer effects, including preventing skin cancers caused by sun damage.

SourceJohns Hopkins Medicine·DateNov 1, 2005
Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

JCI table of contents November, 2005

Researchers found that HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions, which is inversely correlated with successful control of HIV. This mechanism may lead to targeted immunotherapies for HIV.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateOct 13, 2005

New findings help to unravel skin cancer's secrets

Researchers have discovered that red hair pigment produces more damaging compounds when exposed to sunlight, increasing the risk of skin cancer. A new topical lotion has also been developed, using a natural protein to repair DNA damage in skin cells.

SourceAmerican Chemical Society·DateAug 29, 2005
GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Ozone layer decline leveling off, according to new study

A recent study suggests that ozone levels in the atmosphere have begun to level off, with some regions even experiencing small increases. However, it is unlikely that the ozone layer will fully recover, and scientists warn that precautions such as UV protection remain vital.

SourceUniversity of Colorado at Boulder·DateAug 29, 2005

SPF may not be enough to protect against skin cancer

Researchers tested various sunscreens and methods on volunteers from multiple countries to establish a standard method for determining IPF. However, the study found that high SPF sunscreens may not provide sufficient protection against immunosuppression, potentially increasing skin cancer risk.

SourceBlackwell Publishing Ltd.·JournalJournal of Investigative Dermatology·DateAug 29, 2005