A new tool developed by Queen Mary University researchers can accurately predict the risk of seizures during pregnancy and up to six weeks after delivery. The EMPiRE tool uses routinely collected data to inform care and close monitoring, potentially reducing maternal and fetal mortality.
A new European study found that families with a higher socioeconomic position are at a greater risk of exposure to environmental chemical contaminants. Pregnant women and their children from more affluent backgrounds had higher levels of pollutants such as PFAS, mercury, and pesticides in their bodies.
Research published in CMAJ found that women whose physician infrequently performs surgical abortions have almost twice the risk of severe complications. High-volume physicians are more likely to recognize and troubleshoot potential problems, resulting in lower complication rates.
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Research found that maternal microbes can impair the gut barrier during pregnancy, leading to increased inflammatory markers and altered placental development. A high-fat diet exacerbated these effects, impacting fetal intestinal development and potentially affecting metabolism after birth.
A Rutgers study found that men over 45 experience decreased fertility and increased pregnancy complications in their partners. Infants born to older fathers are also at higher risk of premature birth, low birth weight, and childhood cancers.
A new study at the University of Utah Health found that drug-induced death is the most common cause of pregnancy-associated death in Utah. Postpartum women who have previously or currently struggle with substance abuse are at greater risk of overdosing.
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Researchers found a connection between intrahepatic cholestasis of pregnancy and non-alcoholic fatty liver disease, suggesting impaired bile acid metabolism as a potential link. Women with ICP were 5.7 times more likely to have a diagnosis of fatty liver disease than controls.
A prospective study of 18,481 pregnant women found obesity in early pregnancy associated with spontaneous abortion, preterm birth, and large birth weight. Being underweight during pregnancy was linked to early neonatal deaths and low birth weight.
A large trial has found that progesterone treatment can increase the chances of a baby being born for women who experience early pregnancy bleeding and have a history of miscarriage. The study involved over 4,000 pregnant women and showed a significant increase in live births among those receiving progesterone treatment.
A recent study published in the European Journal of Epidemiology found a strong link between maternal nut intake during pregnancy and improved cognitive function in children. The research, conducted in Spain, analyzed data from over 2,200 mother-child pairs and discovered that those who consumed more nuts during the first trimester sco...
Researchers have found that anakinra, a long-standing immunosuppressive drug, can diminish fetal deaths and birth defects in mice infected with the Zika virus. The study suggests that targeting placental immune responses may be a viable treatment approach for reducing Zika-related birth defects.
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Research by the University of Saskatchewan found that exposure to inflammation during pregnancy alters brain development, predisposing offspring to psychiatric illness like schizophrenia. Young adult rats exposed to a simulated viral infection displayed abnormal behavior, reduced working memories, and altered fear responses.
A new study finds that women and mice experience changes in their daily schedules and activity levels during the first third of pregnancy. The study suggests that these changes may be related to hormonal influences and could have implications for preterm birth prevention.
The proportion of pregnant women with obesity has doubled from 22% in 2010 to 44% in 2018, according to a new hospital study. The findings also show a rising incidence of caesarean section births alongside increasing BMI.
A new study suggests that prenatal stress may be involved in shaping psychiatric resilience, with high-violence communities showing less frequent depression and PTSD symptoms. Prenatal stress interacts with postnatal stress to influence resilience.
This study reveals lower cigarette use among pregnant US women compared to nonpregnant women, but identical e-cigarette use rates. E-cigarette use is more common among pregnant smokers than nonpregnant dual users.
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A study of nearly 50,000 Danish women found that those with overweight in childhood were more likely to develop hypertensive disorders during pregnancy than normal-weight peers. Women with higher childhood BMI had a significantly increased risk of gestational hypertension and preeclampsia.
Research finds that placental hormone allopregnanolone plays a crucial role in fetal brain development, and its disruption can lead to brain injuries associated with ASD. The study suggests that subtle changes in utero may set the stage for neurodevelopmental disorders later in life.
A Duke University study suggests that giant devil rays may have an unknown birthing zone in nearby waters, which could be a good news for conservation efforts but requires action to limit fishing during birthing months.
A study of over 25 million pregnant women found that quitting smoking during pregnancy significantly lowers the risk of preterm birth. The research also revealed that smoking cessation rates at the start and during pregnancy have increased in recent years.
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A Dartmouth-led study published in JAMA Network Open found that quitting smoking during pregnancy reduces the risk of preterm birth. The probability of preterm birth decreased by up to 20% if cessation occurred at the beginning of pregnancy. However, only about 25% of women who smoked prior to pregnancy were able to quit throughout the...
A systematic review of 631 pregnant women with Marfan Syndrome found an estimated 5.3% prevalence of acute aortic dissections during or after pregnancy. Conservative management with beta-blockers is recommended for type B dissections, while emergency surgical intervention is indicated for type A dissections.
Research from Florida State University finds that pregnant women are more likely to feel 'pushed out' of their workplaces, leading them to opt-out. The study confirms inherent biases against expectant mothers and highlights the need for employers to provide equal career support to both men and women with children.
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Researchers found a dramatic change in bacterial composition during late pregnancy, with Bifidobacterium increasing in relative abundance. Progesterone regulates microbial growth, aiding in baby development and potentially impacting preterm delivery.
A new study found that routine ultrasounds can eliminate undiagnosed breech presentations, lower emergency caesarean sections, and improve maternal health. The research suggests that screening for breech presentation near term could be introduced in a cost-effective manner.
The US Preventive Services Task Force now finds no evidence to support or refute screening for elevated blood lead levels in asymptomatic children under 5 years old and asymptomatic pregnant women. This recommendation updates the 2006 statement and is based on a review of existing literature.
Regular ultrasounds at 36 weeks' gestation can identify undiagnosed breech presentations, reducing the risk of complications for both mothers and babies. By performing these scans, hospitals could potentially save thousands of pounds annually while improving patient outcomes.
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A new study found that female rats exposed to maternal immune activation during pregnancy exhibit autism- and schizophrenia-like behaviors, similar to their male siblings. The researchers argue that this limitation may contribute to conflicting results in the field of psychiatric disorders.
A new study in rats reveals that marijuana exposure during pregnancy can lead to behavioral and memory problems in babies. The research pinpoints how the drug alters neural connections in the hippocampus, a key area for learning and memory.
The Society for Maternal-Fetal Medicine has released new guidelines for diagnosing and treating sepsis in pregnancy, emphasizing the importance of early recognition and management. The recommendations are designed to improve care and prevent organ damage caused by sepsis, with a focus on increasing maternal survival rates.
Young children who live close to a major roadway are twice as likely to score lower on tests of communications skills. Children born to women exposed during pregnancy to higher-than-normal levels of traffic-related pollutants have a small but significantly higher likelihood of developmental delays.
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A new study published in EClinicalMedicine found that pregnant women who sleep on their backs are at a higher risk of stillbirth, with the risk increasing by 2.6 times after 28 weeks of pregnancy. The NHS has now incorporated the findings into its Saving Babies' Lives care advice information for pregnant women.
Researchers found that modulation of immune system during pregnancy is similar in women with and without lupus. In healthy pregnancies, key immune genes are quieted after embryo implantation, while those with preeclampsia or complications show downregulation of these genes.
A new study found that online diet goal-setting helped women with normal body weight achieve healthy weight gain during pregnancy. However, the tool was not effective for women with higher BMI levels, suggesting a need for personalized approaches to dietary change.
A study has identified early changes in RNA molecules present in the blood that can predict the likelihood of preeclampsia in lupus patients. The researchers also found that failure to modulate immune pathways during healthy pregnancy is associated with complications in pregnant lupus patients.
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A new study found that offspring born to mice exercising during pregnancy had increased levels of proteins associated with brown adipose tissue and higher body temperatures, indicating improved thermogenic function. This led to reduced weight gain on a high-fat diet and fewer symptoms of metabolic diseases in later life.
Children born to women with preeclampsia have higher blood pressure during childhood and increased stroke risk. Treating preeclampsia with sildenafil citrate may help protect offspring's cardiovascular health.
A pilot study conducted in Kenya identified a safe and effective strategy to help women with HIV have children, despite the infection being passed on to their babies. The study showed six live births without HIV transmission among 23 couples participating in timed vaginal insemination.
A new AI approach analyzes time-lapse images of embryos to predict pregnancy potential, improving IVF success rates and minimizing multiple pregnancies. Researchers used a large dataset of human embryos to train an algorithm that can classify embryo quality with high accuracy.
A study by Lawson Research Institute found evidence of a strong association between exposure to sulfur dioxide during pregnancy and adverse birth outcomes, including low birthweight and preterm birth. Pregnant women were 3.4 times more likely to have a low birthweight baby for every 1-part per billion increase in sulfur dioxide.
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Recent studies have shed light on the impact of environmental toxins, food additives, and pain management on human health. Research has found that certain antioxidants can protect cells from harm caused by hexavalent chromium, while other substances may weaken the immune system or cause dental damage.
In a groundbreaking study, scientists at the University of Sydney observed a normally live-bearing Australian lizard lay eggs and then weeks later, give birth to a live baby from the same pregnancy. This unusual reproductive trait is known as bimodality, where some individuals lay eggs while others give birth to live young.
A study published in Economics & Human Biology found that pregnant women who commute at least 50 miles to work are at a higher risk of having low-birth-weight babies. The longer the commute, the greater the risk. Long commutes also led to under-use of prenatal care, which could exacerbate birth outcomes.
A study published in The Lancet Diabetes & Endocrinology journal found that metformin can halve the risk of late miscarriage and preterm births for women with polycystic ovary syndrome (PCOS). Women who received metformin during pregnancy also gained less weight, but there was no effect on gestational diabetes or pre-eclampsia.
A recent study by the University of Kentucky has identified a potential cellular mechanism that connects smoking during pregnancy with an increased risk of offspring obesity later in life. The research found that expectant mothers who smoke cigarettes during pregnancy induce distinct changes in chemerin gene expression in their offspring.
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A recent study published in The FASEB Journal found that low oxygen levels during fetal development can lead to premature ovarian ageing and reduced egg availability. Researchers exposed pregnant rats to chronic hypoxia, leading to accelerated ageing of the ovaries and fewer eggs available for future reproduction.
A Norwegian University of Science and Technology study found that children exposed to metformin in utero had a higher risk of obesity. The research, which followed 141 children from PCOS mothers for 5-10 years, also showed no link between metformin use and healthier growth conditions.
Pregnant women who use cannabis may slightly increase the risk their unborn child will develop psychosis later in life. The study's findings raise concerns about prenatal exposure to cannabis and its potential long-term effects on brain development.
The study found that the widely used antimalarial sulphadoxine-pyrimethamine (SP) is no longer effective in preventing malaria in areas with high levels of resistance. In areas where more than 37% of parasites carry six mutations, the effectiveness of SP appears to be fully compromised. The researchers are calling for further investiga...
A recent study published in the European Journal of Preventive Cardiology has found that paternal smoking and maternal passive smoking can significantly increase the risk of congenital heart defects in offspring. The analysis of 125 studies involving over 137,000 babies with congenital heart defects revealed a 74% increased risk for me...
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Research found that HIV-exposed but uninfected (HEU) adolescents and young adults are at higher risk of obesity and reactive airway disease compared to their non-exposed peers. Lower prenatal maternal CD4 count was associated with increased body mass index (BMI) in HEU adolescents.
A large study published in The New England Journal of Medicine found that treating women with thyroid antibodies and normal thyroid function with Levothyroxine did not improve the chances of live birth. The study showed similar outcomes in both groups, with 56.6% and 58.3% becoming pregnant, respectively.
Research suggests that sperm DNA damage in male partners may cause recurrent pregnancy loss (RPL), with affected men having twice as much DNA damage as healthy counterparts. High levels of reactive oxygen species were also found, which can damage cells like sperm.
A high-fat, high-sugar diet in pregnant mice causes heart problems in their offspring, which are then passed down to subsequent generations. The defects in heart mitochondria are thought to be caused by epigenetic changes in the mother's eggs.
A University of Maryland School of Medicine study has identified seven bacteria associated with increased risk of spontaneous preterm birth, while higher levels of a natural antimicrobial peptide may lower this risk. The findings hold promise for early diagnosis and prevention of premature births, particularly in African American women.
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A new research suggests that a single allergic reaction during pregnancy can prompt significant changes in the brains of offspring, leading to more male-like behavior and brain development. Female rats born to mothers exposed to an allergen during pregnancy exhibited higher levels of male-like behavior and brain changes.
A new study found seven bacteria and immune factors in the vagina and cervix that increase or decrease the risk of spontaneous preterm birth, particularly in African-American women. Higher levels of β-defensin-2 lowered the risk of sPTB associated with cervicovaginal microbiota.
Researchers at Johns Hopkins Medicine studied 22 US state and federal prisons, tracking 1,396 pregnant women over 12 months. Most pregnancies resulted in live births with no maternal deaths, a significant improvement compared to general population statistics.
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A new study published in the Journal of Public Health found that immigrant women in Norway are more likely to be overweight during pregnancy. The study, which analyzed data from 219,555 deliveries between 2006 and 2014, also found a significant association between country of birth and weight status.
A Norwegian study found that women under 30 have the lowest risk of miscarriage, while those over 45 face a 53% risk. Previous pregnancy complications also increase the risk, with pre-eclampsia not being a factor.