Researchers at Fox Chase Cancer Center have discovered a gene expression pattern in breast tissue that differs between post-menopausal women who had children and those who did not. This genomic signature may help scientists understand why pregnancy reduces breast cancer risk and develop chemopreventive strategies.
Research suggests that living near a busy road junction increases the likelihood of premature birth by 4.4%. The study found that even short distances from freeways can have negative effects on gestation times. Reducing traffic emissions through improved vehicles or public transport use could provide immediate health benefits.
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The ALSPAC project will investigate how behavior before birth, infancy, childhood, and adolescence affect adult health. Researchers will collect data from three generations: the original mothers and children, their adult offspring, and now, grandchildren.
A new study published in Proceedings of the National Academy of Sciences reveals that brain growth in babies is linked to maternal investment, including duration of pregnancy and breastfeeding period. The research suggests that longer pregnancies and breastfeeding periods result in bigger brains for babies.
A University of Georgia study found a supervised, low-to-moderate intensity weight-lifting exercise program to be safe and beneficial for pregnant women. The research showed that participants increased their strength without experiencing musculoskeletal injuries or significant changes in blood pressure.
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Research published in The FASEB Journal found that rats whose mothers ate high-fat, high-sugar diets had babies that preferred similar foods. This study suggests that exposure to junk food during pregnancy and breastfeeding may shape a child's eating habits.
A University of Rochester Medical Center study found that a mother's iron deficiency early in pregnancy can have a long-lasting effect on the child's brain development, even if it's not severe enough to cause anemia. The research suggests that monitoring a pregnant woman's iron status beyond anemia is crucial.
Researchers identified genetic mutations in women with lupus and/or antiphospholipid antibodies that may predispose them to preeclampsia. The study's findings suggest new targets for treating the condition and raising the possibility of tests to identify women at increased risk
Researchers identified genetic errors in women with autoimmune diseases and preeclampsia, suggesting new treatments and screening tests. The study found mutations in three genes involved in the immune response to injury, providing a potential link between preeclampsia and atypical hemolytic uremic syndrome.
A recent study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that adolescent girls exposed to heavy alcohol use during their first trimester were three times more likely to develop conduct disorder. The study examined 592 adolescents and their mothers or caretakers, utilizing data from a long...
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Researchers at Children's Hospital of Philadelphia found that feeding rats antioxidants during pregnancy prevented obesity and glucose intolerance in their offspring. The study suggests that preventing oxidative stress during pregnancy may lower the risk of childhood obesity.
A Norwegian study found that women unhappy with their relationships were more likely to experience depression during pregnancy. A good relationship, on the other hand, served as a buffer against everyday stresses, helping women cope better with work-related issues, financial problems, or moving house.
A recent study found that daily iron supplements do not significantly increase hemoglobin levels in healthy pregnant women, but can help alleviate iron-poor blood conditions in Africa. Researchers followed over 1,000 pregnant women and discovered that all participants ended with similar iron levels after three months.
The Boston Medical Center will receive a $245,000 grant to enhance its Centering Pregnancy program, which has been shown to decrease late preterm delivery by up to 40% and increase pregnancy knowledge and satisfaction with care. The grant aims to promote preventive care and address health disparities in Massachusetts.
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A study published in Pediatrics found that pregnant non-smokers exposed to second-hand smoke have a higher risk of delivering stillborn babies or babies with congenital birth defects. Passive smoking increased the risk of stillbirth by nearly one-quarter and was linked to a 13% increased risk of congenital birth defects.
The March of Dimes is investing $2.4 million in new funding for research on predicting and preventing preterm birth, a leading cause of infant death. Five scientists will study low doses of carbon monoxide, genes, blood tests to identify high-risk women, and fetal membrane weakening.
Poor diet during pregnancy increases offspring's vulnerability to aging effects, leading to increased risk of type 2 diabetes and age-related diseases. The study reveals a novel mechanism by which maternal diet interacts with epigenetics to influence gene expression in offspring throughout life.
A study found that women who have experienced pregnancy loss may continue to suffer from depression and anxiety, even after having a healthy baby. The study suggests that previous pregnancy loss should be taken into account when assessing the risk of antenatal or postnatal depression.
Researchers link Henry VIII's reproductive issues, including multiple miscarriages, to Kell blood group incompatibility. The study also suggests McLeod syndrome as a possible cause for his dramatic physical transformation and mental instability.
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A €2.6 million research program is training Malawian clinical officers to improve prenatal care and reduce childbirth mortality rates. The goal is to educate 50 clinical officers, who will then teach others, and ultimately assess the impact on mortality rates.
Women who experience depression and anxiety after a miscarriage may continue to feel these symptoms after a healthy child is born. The Avon Longitudinal Study of Parents and Children found that mental health problems associated with miscarriage or stillbirth do not end with the birth of a healthy baby, but can persist for several years.
Researchers have discovered that adding one or two drugs to the standard ZDV treatment can significantly reduce the risk of HIV transmission from mother to infant. The study found that treatment with two and three drug regimens reduced HIV transmission by more than 50%.
Researchers developed an intervention to help pregnant women control their weight, with normal-weight women more likely to stay at a healthy weight. The program increased the chance of returning to pre-pregnancy weight six months after delivery, but had limited success for obese or overweight women during pregnancy.
A study by Amanda Phipps at Fred Hutchinson Cancer Center found that full-term pregnancies increase the risk of triple-negative breast cancer, while never giving birth lowers it. Conversely, childless women face a higher risk of estrogen-receptor-positive breast cancer.
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A recent study found that maternal fructose consumption during pregnancy results in sex-specific changes in fetal and neonatal endocrinology, with female fetuses showing higher leptin and blood glucose levels. Male offspring also exhibit increased plasma fructose levels and hypoinisulinemia.
Researchers found a significant decrease in unintended pregnancies and abortions when women received a one-year supply of oral contraceptives. The study suggests that a larger supply allows for more consistent use, reducing the need for frequent clinic visits or resupply trips.
Researchers at The Wistar Institute and University of Pennsylvania School of Medicine have discovered protein markers that could predict ectopic pregnancies. A panel of biomarkers, weighing individual proteins' relative importance, may create a more sensitive and reliable test for detecting ectopic pregnancies.
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Scientists have discovered biomarkers in the blood of pregnant women that could lead to early diagnosis of ectopic pregnancy. Almost 70 proteins were found to occur at unusual levels in women with EP, with one protein called Adam12 appearing 20 times lower than in normal pregnancies.
Researchers at North Carolina State University have discovered a gene associated with the immune system that is overexpressed in placentas of women with preeclampsia, leading to a better understanding of the disorder. The finding may lead to improved screening and prenatal care for these patients and their babies.
The use of electronic fetal heart rate monitors significantly lowers infant mortality, especially in high-risk pregnancies, according to a recent study. The findings show a 53% decrease in early neonatal mortality among infants with EFM.
A study found that female rats given folic acid supplements before conception and during pregnancy had higher rates of breast cancer, with twice as many tumours and faster-growing tumours. The researchers stress the need for more research to determine whether this applies to humans.
A study found that the standard third-trimester GBS test did not accurately predict its presence during labor, while a rapid test performed at labor showed excellent accuracy. The test's performance varied among racial groups, with Hispanic and African-American women more likely to have discordant results.
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Research led by Dr. Errol Norwitz found that progesterone prevents preterm labor by hindering apoptosis in fetal membranes, resulting in stronger and thicker fetal membranes. This study contributes to the understanding of what triggers labor and the role of progesterone in preventing premature birth.
Researchers found that women administering their own patient-controlled epidural analgesia (PCEA) used 30% less analgesia than those with continuous epidural infusion (CEI), while reporting similar levels of satisfaction. The study also showed a trend toward reduction in instrumented vaginal deliveries.
A randomized clinical trial found that early amniotomy in labor induction can shorten delivery time by over 10 percent and increase the likelihood of delivery within 24 hours without adverse effects. This method also greatly increases the comfort of the mother.
A recent study led by Dr. Errol R. Norwitz found that three proteins XIAP, BID, and Bcl-2 play a crucial role in preventing preterm labor by hindering apoptosis in the fetal membranes. This breakthrough research sheds light on the mechanism behind progesterone's success in preventing preterm birth.
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Researchers link declining litter sizes to loss of sea ice in Hudson Bay, predicting significant threat to western polar-bear population. Climate change could reduce energy availability for pregnant females, leading to failed births or natural abortions.
Researchers used fruit flies to study fetal alcohol syndrome, finding that prenatal alcohol exposure can cause developmental problems such as intellectual disabilities and abnormal facial features. The study establishes a new model system for studying FAS, which may lead to the development of new therapies.
Researchers found that obese mothers who lost weight before pregnancy had healthier male offspring with reduced triglycerides and insulin resistance. The study suggests pre-pregnancy dietary intervention can reverse adverse metabolic effects of maternal obesity on offspring.
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Teenage girls and young women infected with HIV are more likely to get pregnant and experience pregnancy complications compared to their HIV-negative peers. The study found that behaviorally acquired HIV-infected teens were seven times more likely to have multiple pregnancies than those infected at birth.
Potential risks of sex in pregnancy include premature labour, pelvic inflammatory disease, and blood clots, but the evidence is often contradictory and limited. For low-risk women, frequent intercourse may increase the risk of premature labour, while restricted activity is recommended for those at high risk
A study by University of Nottingham researchers found that areas with pharmacy emergency birth control schemes saw a five percent increase in STIs among teenagers and a 12 percent hike in under-16s. The study also suggests that EBC schemes may be associated with a small increase in teenage pregnancies.
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A large trial in Uganda found that treating pregnant women for worm infections increased their child's chances of developing eczema. The study supports the 'hygiene hypothesis', which proposes that exposure to infections can modify the immune system and protect against allergies.
A recent Norwegian study found that nearly one in ten pregnant women consumes organic food regularly, with organic eggs and vegetables being the most popular choices. Women who consumed organic food were more likely to have higher education, lower incomes, and frequent exercise habits.
A Norwegian study found that mothers' satisfaction with their relationship during pregnancy is a strong predictor of overall satisfaction, peaking at 6 months old. However, both forms of satisfaction decline over time during infancy and toddlerhood.
In sub-Saharan Africa, an estimated 32 million pregnant women are at risk of malaria every year. Despite national policies to reduce and control malaria during pregnancy, coverage rates of two key interventions, insecticide-treated nets and intermittent preventive treatment, remain inadequate.
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A study published in The Lancet Infectious Diseases found that malaria protection methods for pregnant women in sub-Saharan Africa are underutilized. Despite WHO policy, estimated coverage of intermittent preventive treatment (IPTp) is only 25% and insecticide-treated nets (ITNs) are used by just 17% of pregnant women at risk.
A study by Christine Aurich's group found that altrenogest treatment reduces the risk of miscarriage in older, pregnant mares. The treatment has no effect on hormone levels but enables foetuses to recover and grow at a normal rate during critical periods of development.
A systematic review found that antioxidant supplements may benefit couples trying to conceive naturally, particularly when the male partner takes antioxidants. The review of 34 trials involving over 2,800 couples suggests a higher likelihood of pregnancy or live birth when antioxidants are used.
A study found that moderate decreases in maternal nutrition during early pregnancy impaired fetal brain development, including decreased cell-to-cell connections and growth factors. The research uses a nonhuman primate model to demonstrate the importance of good maternal health and diet on fetal development.
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A new study from UCSF found that virtually all pregnant women in the US are exposed to multiple chemicals, including some banned since the 1970s. The study identified over 163 chemicals, with many linked to adverse health outcomes such as preterm birth and childhood morbidity.
A new genetic blood test predicts IVF success by identifying the FMR1 gene subtype, with different subtypes associated with varying pregnancy rates. The test also suggests a link between autoimmunity and infertility, potentially informing fertility planning.
A new study reveals that women who have had chlamydia are at greater risk of an ectopic pregnancy due to a lasting effect of the infection. Researchers found that infected women produce more PROKR2 protein in their Fallopian tubes, increasing the likelihood of implantation.
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The study found that a specific protein called GRA15 triggers inflammation in the host, leading to brain damage. Researchers hope to develop new drugs or vaccines to block this process and prevent chronic infections.
A significant increase in MMP-1, an enzyme produced in tissues under conditions of inflammation, was found in the blood vessels of women with preeclampsia, explaining edema and proteinuria. This finding also suggests a new mechanism for hypertension, with PAR1 activation potentially causing blood vessel contraction.
A study published in The Lancet found that deworming treatment during pregnancy does not affect infant immune responses to vaccines or infectious disease incidence. The authors suggest that the value of this intervention should be re-examined, and policy recommendations be reviewed.
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Researchers found that vaccinating pregnant women against influenza prevents hospitalization in infants by 91.5%. This effective strategy protects young infants without a vaccine, and is cost-effective as it protects two individuals.
A population-based survey of neonaticides found the true incidence to be 2.1 per 100,000 births, five times higher than official estimates. Low maternal self-esteem and emotional immaturity were identified as key drivers.
Researchers identified significant effects of different treatment options on infant outcomes, including higher rates of congenital malformations in premature deliveries. The study suggests that pregnant women with breast cancer should continue their pregnancy and receive standard treatment recommendations.
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Researchers from Michigan State University are investigating the relationship between cesarean-section deliveries and degenerative spondylolisthesis, a condition causing lower back pain and nerve damage in women. The study aims to quantify muscle function objectively and document variables in women with and without the disease.