Articles tagged with Disease Control
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The Society for Healthcare Epidemiology of America and Infectious Diseases Society of America have released new clinical practice guidelines for Clostridium difficile infection in adults. The guidelines update recommendations on diagnosis, treatment, and infection control measures to address changes in epidemiology and disease severity.
The National Guard Health Affairs in Saudi Arabia has been recognized for its efforts to reduce healthcare-associated infections, including an 82% reduction in central line associated BSI rates and an 80% reduction in surgical site infection rates. The organization's multidisciplinary team approach has been key to its success.
Scientists found that emphasizing non-pathogen specific infection control practices, such as hand hygiene and chlorhexidine bathing, significantly reduced MRSA rates. The study observed a 91% reduction in central line-associated bloodstream infections, a 62% reduction in catheter-associated urinary tract infections, and a 92% reduction...
Researchers successfully created genetically engineered mosquitoes that can deliver a malaria vaccine through blood feeding, raising hopes for a new strategy in disease control. The study, led by Associate Professor Shigeto Yoshida, targeted the saliva gland of Anopheles stephensi mosquitoes and induced protective immune responses.
A French national program to reduce healthcare-associated infections (HAIs) reported important successes with mandatory public reporting. The program led to a drop of 40% in MRSA cases and improved infection control measures across the country. Key initiatives included advancing research, improving communication with patients, and stan...
A new study reveals that regulating intestinal inflammation can prevent colon cancer by controlling the activity of two proteins, Caspase-1 and Caspase-12. Caspase-1 plays a crucial role in maintaining the intestinal barrier, while its absence leads to uncontrolled cell proliferation and increased risk of colorectal cancer.
The American Society for Microbiology honors Samuel L. Katz with the Maurice Hilleman/Merck Award for his decades-long work on vaccine development. Katz, a renowned expert in vaccine research, has made significant contributions to pathogenesis, vaccine discovery, and disease prevention.
Researchers at Cornell University have identified a protein involved in mosquito urination, which can help control the spread of diseases like dengue fever. By blocking this protein's function, mosquitoes may be limited in their ability to survive after feeding on blood.
Researchers found that climate change is one factor contributing to the rise of malaria in highland areas, particularly in East Africa, Indonesia, and Afghanistan. However, they also identified other key factors, such as migration and land-use changes, that are likely driving the spread of the disease.
A recent study found that insufficient vitamin C levels can be fatal to mice during pregnancy. The Slc23a1 protein plays a vital role in vitamin C absorption and tissue accumulation. Researchers identified key functions for this transporter, including renal reabsorption and perinatal survival.
Researchers found that ghrelin reduced liver fibrosis by 25% in treated rats, prevented acute liver damage, and decreased oxidative stress and inflammation. Human studies also showed lower ghrelin serum levels in patients with chronic liver disease, suggesting potential therapeutic benefits.
Dendritic cells produce higher levels of α-defensins 1-3, associated with slower HIV disease progression and potential therapeutic implications. The findings open a new line of investigation for treating HIV/AIDS.
A recent Institute of Medicine report reveals 3.5-5.3 million people in the US have chronic HBV or HCV infections. Efforts to control these diseases are hindered by lack of knowledge among healthcare providers and the public, resulting in 15,000 deaths from liver cancer or related diseases annually.
A review of airline passengers and crew exposed to TB found no evidence of transmission during air travel. Only 10 out of 4328 passengers tested positive, with no reported cases of active TB resulting from air travel.
A software program created by Andrew Cohen analyzes time-lapse images to identify changes in cell behaviors, predicting the types of specialized cells a stem cell will produce. The software is 87% accurate in determining specific 'offspring' a stem cell will ultimately produce, and 99% accurate in predicting when self-renewal will end ...
A large multiple sclerosis study found that 62.5% of participants exhibited venous insufficiency, a condition linked to blood flow restrictions in the brain. The study suggests a potential association between CCSVI and MS disease progression.
Researchers at Henry Ford Hospital found that online programs providing practical tips on fruits and vegetables increased participants' daily intake by more than two servings. Many participants continued using the program and reported involving their family members.
The study shows that a simple, standardized checklist can virtually eliminate central-line catheter bloodstream infections. By combining the checklist with culture change and continuous monitoring, hospitals can sustainably reduce infection rates, making them more transparent to patients.
Researchers propose integrating NTD interventions into the regular health system, leveraging resources from malaria, HIV/AIDS, and tuberculosis programs. Careful planning and community engagement are crucial for successful integration and co-implementation of these efforts.
Lymphatic filariasis, onchocerciasis, and other neglected tropical diseases (NTDs) cause significant morbidity and mortality globally. NTDs have been hindered by limited funding and coordination, but successful control initiatives like onchocerciasis elimination demonstrate the potential for progress.
Researchers found that nasal allergies may be involved in some cases of chronic sinus disease, suggesting a potential link between the two conditions. The study suggests using imaging tests to diagnose and treat patients with nasal allergies who also have chronic sinus disease.
A new study finds that alcoholics can improve their postural sway with prolonged sobriety, but the improvement may not fully erase the problem of instability. Researchers found that stabilizing factors such as turning on a light or walking with feet apart can help improve standing stability in sober alcoholics.
The Hebrew University has received a $5 million grant to study visceral leishmaniasis in Ethiopia, also known as Kala-azar. This collaborative project aims to identify weak links in the transmission cycle and devise methods for disease control, particularly in HIV/AIDS-endemic areas.
A comprehensive infection control program at the Seattle Cancer Care Alliance successfully suppressed H1N1 cases among immunocompromised cancer patients, despite a high-risk environment. The program's rigorous screening measures, isolation protocols, and staff vaccination policies significantly minimized transmission and acquisition.
A large-scale genetic study has identified seven genes that increase an individual's susceptibility to leprosy, a chronic infectious disease affecting skin and peripheral nerves. The discovery highlights the role of innate immune response in leprosy development and may lead to early diagnosis and treatment.
Researchers found that strict glucose control reduces cardiovascular issues for diabetics with fewer health problems, but not those with long-term serious coexisting conditions. Firm glucose control may benefit patients with multiple health issues.
The National Heart, Lung, and Blood Institute has approved 13 contracts to develop and implement science-based approaches to improve asthma control. The projects will focus on implementing evidence-based national guidelines for diagnosing and managing asthma in diverse communities, including rural, urban, and suburban settings.
NTDs like anemia, schistosomiasis, and human hookworm infection impair reproductive health and increase the transmission of STIs. Controlling these diseases can improve maternal health outcomes, reduce infant mortality, and promote gender equality.
Climate change poses a fundamental threat to global health, particularly for vulnerable populations. Strengthening health systems and investing in cheap and proven public health interventions can accelerate progress towards the MDGs and help mitigate climate change.
A recent review highlights the need for improved asthma control in preschoolers, with key findings including the use of inhaled corticosteroids as a regular therapy for children with severe symptoms. The authors emphasize the importance of considering alternative conditions if children do not respond to optimal therapy.
A recent study published in BMC Public Health suggests that immediate and aggressive spending of $60 billion on HIV/AIDS treatment could end the epidemic globally. The research, which analyzed a leading-edge mathematical model, predicts that an accelerated approach over five years is necessary to control the spread of the disease.
A new type of T-helper cell, called Th22 cells, has been discovered by researchers from Imperial College London. These cells play a special role in overseeing and coordinating immune cells that cause inflammation in chronic and allergic inflammatory diseases.
A new study by University of Michigan researchers found that people with less education are more likely to get H1N1 and the flu vaccine may be less effective in them. The study suggests that lower socioeconomic status can make it harder for adults of all ages to fight off new infections.
The Global Action Plan for the Prevention and Control of Pneumonia outlines a six-year plan to control the disease, with a focus on promoting exclusive breastfeeding, vaccinations, and effective case management. Implementing these interventions could save more than one million lives each year.
Malaria eradication remains an elusive goal despite progress in controlling the disease, requiring multiple activities, interventions, and approaches. Scientists must adapt their strategies to address changing parasite behavior and distribution, developing new tools and interventions to keep ahead of emerging challenges.
Researchers at UC Davis have identified nonanal as the dominant odor naturally produced in humans and birds that attracts Culex mosquitoes, a key step towards controlling mosquito-borne diseases. The study also found that combining nonanal with carbon dioxide increases trap captures by over 50%.
A new integrated survey protocol identified areas requiring mass treatment for schistosomiasis and intestinal worm infections in Southern Sudan. Lymphatic filariasis and loiasis were found to be extremely rare, with only four individuals testing positive or reporting symptoms.
Deborah Friberg, COO and Executive Vice President at WakeMed Health and Hospitals, has been recognized by APIC with the first annual Healthcare Administrator Award. She supports infection prevention and control through various initiatives, including MRSA reduction and hand hygiene compliance.
The study emphasizes the role of population mobility in spreading drug-resistant diseases worldwide. Researchers propose a new approach that considers the 'human factor' in health policy and processes to combat this growing threat.
A national study found that retirees who continue to work in a bridge job experience fewer major diseases and functional limitations than those who fully retire. People whose post-retirement jobs are related to their previous careers report better mental health.
Researchers found that high Treg levels protect against severe West Nile virus disease in humans and mice. Tregs suppress the function of other immune cells, preventing lethal infection.
The University of Adelaide's Professor Konrad Jamrozik has spent 30 years campaigning against smoking and helping smokers quit. He has contributed significantly to tobacco control through his research, clinical trials, and advocacy.
A recent study by Columbia University's Mailman School of Public Health found that home healthcare nurses are at risk of needlestick-type injuries, with nearly 10,000 reported annually. The study also revealed a correlation between stressful household conditions and increased risk of needlesticks.
Buruli ulcer is caused by mycobacterium ulcerans and primarily affects poor rural communities in tropical countries. The new study aims to identify the natural reservoir for the disease, its activation, and transmission to humans.
A new study from UAB researchers found that childbearing is associated with a higher incidence of the metabolic syndrome in women. Women who had gestational diabetes were nearly twice as likely to develop the syndrome as those without it. Lifestyle changes, such as exercise and healthy eating, may help prevent disease later in life.
This article provides practical guidance for diagnosing adult asthma, including occupational asthma, using patient history, physical examination, and definitive diagnostic testing like spirometry. The goal is to accurately diagnose or exclude the possibility of asthma and treat patients accordingly.
Daily commuting patterns in mega-cities may contribute to the resurgence of mosquito-borne diseases like dengue fever. Researchers suggest looking beyond traditional transmission clusters and considering novel ways to control community transmission.
Researchers at Hebrew University of Jerusalem discover Lysyl-tRNA synthetase's regulatory role in gene expression, potentially leading to new therapies for diseases like AIDS and breast cancer. The molecule is also involved in viral replication and high levels have been observed in certain cancers.
The study found that regular CGM use is the primary factor in achieving better diabetes control, regardless of age. People using CGM devices six days per week or more showed similar levels of improvement in diabetes control across all age groups, from children to adults.
Researchers found that house screening reduced mosquito numbers by 49-59% and malaria-related anaemia in children by half. The authors suggest integrating house screening into vector management programs to combat malaria.
A study found that children in Ethiopia who received azithromycin for trachoma had a 49% lower odds of death compared to those who didn't receive the antibiotic. The treatment may have reduced mortality from pneumonia, diarrhea, and malaria, major causes of death in children in trachoma-endemic areas.
Researchers identified miR-143 and miR-145 as key regulators of VSMC contractility and blood pressure. The study found that mice lacking these microRNAs had reduced contractile VSMCs and increased tissue matrix-producing cells, leading to signs of blood vessel disease.
A study found that miR-143 and miR-145 regulate the contractile nature of vascular smooth muscle cells, with their absence leading to increased tissue matrix production and signs of blood vessel disease. The findings suggest these microRNAs could serve as therapeutic targets for enhancing blood vessel repair.
Researchers have discovered a new treatment that significantly improves disease symptoms in a genetic disorder, highlighting skeletal muscle as a viable target tissue. The therapy targets the muscle and reduces accumulation of toxic protein, improving motor performance and survival in mice with spinal and bulbar muscular atrophy.
A Kansas State University biochemist is studying the lens in diabetes patients with a focus on protein kinase C gamma (PKC gamma) and gap junctions. Researchers hope to design drugs that can prevent diabetics from losing PKC gamma, which leads to lens cell damage.
Researchers describe a mathematical model that helps fine-tune artificial biomolecular switches, shedding light on their evolution and potential applications in detecting chemicals and disease markers.
The US public spends billions annually on CAM therapies, including herbal supplements, meditation, and acupuncture. Approximately 11.2% of healthcare expenditures are attributed to CAM, totaling $33.9 billion out-of-pocket expenses.
A new study by researchers at the University of California, Davis, and Emory University found that human movement is a crucial factor in understanding disease transmission for mosquito-borne diseases like dengue. The study used satellite-based GPS and culturally-sensitive interviews to track individual human movement, revealing how fin...
Researchers present findings on stimulating metabotropic glutamate receptors to stop glutamate release in brain cells, potentially reversing Parkinson's disease symptoms. Current treatments only alleviate symptoms, but new approach aims to protect and repair dying cells.
The HPV-16/18 AS04-adjuvanted vaccine shows high efficacy against precancerous cervical lesions, with cross-protective efficacy against other oncogenic HPV types. The vaccine also demonstrates efficacy in universal mass vaccination and catch-up programmes, potentially reducing cervical cancer incidence.