Articles tagged with Disease Control
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A recent investigation found that a common strain of C. difficile, known as BI/NAP1, is endemic in Chicago-area acute care hospitals, putting patients at risk for severe disease. The outbreak strain was spread through patient transfers between healthcare facilities.
Researchers identified five core themes for successful implementation of evidence-based practices in Intensive Care Units (ICUs) to reduce Methicillin Resistant Staphylococcus aureus (MRSA) infections. Engaging front-line staff, building multi-disciplinary teams, and acquiring top management support are critical commonalities.
A large international study has identified 29 new genetic variants associated with multiple sclerosis, providing key insights into the biology of the disease. The research highlights the pivotal role of the immune system in causing damage and helps explain the nature of the immune attack on the brain and spinal cord.
Increased hand hygiene knowledge among healthcare workers and elementary school children significantly reduces the risk of transmitting infections. A targeted intervention program showed a 66% decrease in pupil absences after teaching hand disinfection theory and practice.
North Carolina State University is leading a $25 million project to study human noroviruses across the food supply chain. The goal is to design effective control measures and reduce virus-caused food-borne illnesses, which affect over 5 million people in the US annually.
A recent study suggests that mitigating chytridiomycosis through different infection control methods could largely prevent local extinctions and outbreaks of the disease. Researchers have identified successful pilot studies in Spain, including a heat therapy treatment using itraconazole, which has increased amphibian survival rates.
The article highlights the connection between neglected tropical diseases (NTDs) and HIV/AIDS, proposing ways to integrate NTD treatment programs with HIV/AIDS initiatives. Studies show that areas with high NTD infection rates also have high HIV/AIDS prevalence, and co-infections can exacerbate HIV/AIDS.
A bacterial outbreak of Burholderia cepacia complex was linked to contaminated nasal spray products, leading to a national recall. The investigation highlighted the need for improved testing protocols in the production and distribution of over-the-counter pharmaceuticals.
A study involving over 5,000 people with ankylosing spondylitis has identified three regions of the genome strongly associated with the condition. The findings suggest that a particular process in cells and genetic variants of ERAP1 interact to affect disease susceptibility.
A nursing initiative at a large academic medical center reduced central line-associated bloodstream infections to zero, saving $200,000 and 2-3 lives. The effort was led by dedicated infection control nurses who implemented best practices, including daily educational meetings and incentive programs.
A new study found that diabetes prevalence has increased globally over the past three decades, with 350 million adults affected. The study also showed that high-income countries such as the USA and Western Europe have higher rates of diabetes than other regions.
The World Health Organization's latest Dengue Bulletin documents the substantial growth of dengue cases in the Americas, Africa, and Asia. The report reveals alarming increases in dengue deaths, with Brazil experiencing a 6.2% rise per year from 1999-2009.
A study from Australia found a significant decrease in high-grade cervical abnormalities in girls aged 17 and younger following the introduction of an HPV vaccination programme. The incidence of high-grade abnormalities fell by 0.38% as compared to before the programme, with no decline seen for low-grade abnormalities or older age groups.
African-Americans have a genetic predisposition to convert dietary PUFAs to inflammatory messengers, increasing risk for chronic diseases like cardiovascular disease and diabetes. The research highlights the importance of personalized nutrition, emphasizing that nutrients may be healthy or harmful depending on individual ancestry.
The American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Healthcare Epidemiology of America (SHEA) have updated their 2003 joint guideline to ensure safe reprocessing of flexible gastrointestinal endoscopes. The guidelines emphasize the importance of high-level disinfection and standardized cleaning procedures.
A study published in the American Journal of Infection Control found that fire stations are contaminated with MRSA, with the most common areas being medic trucks and kitchens. The research suggests that transmission between personnel and environmental surfaces may be occurring, highlighting the need for further studies.
Researchers at UCR identified three classes of volatile odor molecules that can impair or completely disrupt mosquitoes' carbon dioxide detection machinery. The findings offer powerful advantages as potential tools for reducing mosquito-human contact and could lead to the development of new generations of insect repellents and lures.
A study published in the American Journal of Infection Control found that patient cell phones were more likely to contain potentially dangerous bacteria than those of healthcare workers. The researchers also discovered seven patient phones with multidrug-resistant pathogens, highlighting a potential risk for nosocomial infections.
A study of 1032 patients with early RA found that initial treatment with adalimumab plus methotrexate provided high levels of disease control, with 44% achieving sustained low disease activity. Patients who continued treatment maintained good clinical and radiographic responses, even after withdrawing treatment.
Researchers at UTHealth found diabetics are three to five times more likely to contract TB than non-diabetics, with 25% of cases attributed to diabetes. Improved diabetes prevention and management, including screening for TB, can benefit both diseases.
An analysis of ancient Nubian-era mummies found that human alteration of the environment contributed to the spread of schistosomiasis, a water-borne parasitic disease infecting an estimated 200 million people today. The study suggests that ancient individuals were capable of altering their environment in ways that impacted their health.
Studies by MDC researchers have comprehensively quantified gene expression for the first time, revealing that protein production is mainly controlled in the cytoplasm. This discovery highlights where gene expression can get out of control and may provide key insights into diseases such as cancer.
A recent study found that face masks worn by TB patients reduced transmission rates to non-infected patients by 50%. This simple intervention may be particularly effective in areas with limited resources and widespread TB. The results suggest that face masks could be a valuable addition to comprehensive TB infection control programs.
Researchers found improved hypertension control in Canada, with increased awareness and treatment rates among community-dwelling adults. Despite this progress, one-third of Canadians with hypertension still have uncontrolled blood pressure.
Control of infectious diseases such as cholera, diarrhoea, Chagas disease, and those preventable by vaccination have been successful in Brazil. However, failures exist, including the ongoing public health problem of dengue fever and visceral leishmaniasis.
A study published in The Lancet highlights Brazil's success in reducing the burden of infectious diseases, but notes that some programs have failed to control diseases like dengue fever. Despite this, experts argue that investing in human and social capital has led to sustainable economic growth and improved health outcomes.
A new study found that cattle infected with foot-and-mouth disease are only contagious for 1.7 days, sparking hope for reduced culling and improved testing methods. Researchers recommend developing pre-clinical diagnostic tools to detect infected animals before symptoms appear, allowing for more targeted interventions.
Researchers urge the EPA to partner with academic institutions to test and evaluate the risks of high-priority chemicals, prioritizing those that pose a risk to children's health. The authors also propose reforms to the Toxic Substances Control Act to improve chemical policy and reduce exposure to hazardous chemicals.
A study published in the American Journal of Infection Control found that 15% of US nursing homes receive deficiency citations for infection control. The research team discovered a strong correlation between low staffing levels and the receipt of an infection control deficiency citation.
Researchers found that people with diabetes who sleep poorly have higher insulin resistance and worse control of their blood glucose levels. Poor sleep quality was associated with a 23% increase in morning blood glucose levels and a 48% increase in blood insulin levels.
A call for action proposes applying the International Health Regulations to antimicrobial resistance due to its global health threat. However, another expert disagrees that the IHR were intended to tackle all disease threats and that implementation would be impossible.
A recent study published in Canadian Medical Association Journal found no clinically significant difference in the risk of gallbladder disease among women using different formulations of oral contraceptives. The study, which followed over 2.7 million women, suggested that reporting bias may contribute to perceived increased risk associ...
A new intensive diabetes education program has been shown to improve long-term blood sugar control in low-income, poorly educated diabetics. Participants who received the nine-session problem-solving course saw significant improvements in their hemoglobin A1C levels and reductions in high cholesterol and high blood pressure.
Children with inborn errors of metabolism received vaccines on the same schedule as healthy infants without significant increases in ER visits or hospitalizations. However, smaller subsets of children may be at increased risk for adverse events during the immediate post-vaccination period.
A new joint research centre between Liverpool School of Tropical Medicine, Innovative Vector Control Consortium and Saudi Ministry of Health will focus on cutting-edge research for vector-borne disease control. The centre aims to develop innovative ways to monitor and evaluate insect-borne diseases.
Researchers have found alarming rates of antibiotic use and the emergence of multi-drug resistant bacteria, including carbapenem-resistant Klebsiella pneumonia. Electronic faucets are also more likely to become contaminated with bacteria compared to traditional faucets.
The US CDC has released updated guidelines for preventing intravascular catheter-related infections, aiming to eliminate these deadly and costly healthcare-associated infections. The new guide outlines five key prevention strategies based on scientific evidence, which have been proven successful in reducing infections in hospitals.
A collaborative €12 million project, AvecNet, aims to secure the effectiveness of existing malaria control methods by developing and evaluating new insecticides and techniques. The project seeks to overcome insecticide resistance and increase knowledge about mosquito biology and behavior.
Researchers have identified a new virus as the cause of deadly outbreaks in six Chinese provinces, with a mortality rate of 12%. The virus, known as Severe Fever with Thrombocytopenia Syndrome virus, is transmitted through tick bites and affects humans without causing human-to-human transmission.
Elevated p21 protein levels in natural HIV controllers effectively suppress key viral life cycle steps. This ability is associated with increased p21 expression and may be linked to shared mechanisms of immune defense against cancer and HIV.
Research reveals T cells from elite controllers are resistant to HIV infection due to selective upregulation of p21, an enzyme inhibitor. Blocking p21 increases viral gene expression, highlighting potential treatment strategies for vulnerable patients.
A new Johns Hopkins study suggests that older, less expensive medications like metformin can be just as effective in controlling type 2 diabetes as newer, more expensive options. The research also found that metformin was associated with fewer side effects, including weight gain and cholesterol level increases.
Researchers at the University of California have discovered a new spider toxin that targets T-type and N-type calcium channels, which play a role in congestive heart failure, hypertension, epilepsy, and pain. The toxin offers a new target for studying these channels and developing drugs to treat human diseases.
A recent study published in the American Journal of Infection Control found that community gym surfaces do not appear to be reservoirs for MRSA transmission. The researchers collected 240 samples from three local gyms and found none to be positive for MRSA or MSSA, suggesting that aggressive disinfection programs may not be warranted.
A significant decline in new cases of sleeping sickness has sparked renewed efforts to eliminate the disease as a public health problem. Recent literature highlights promising signs of progress, including leadership from the WHO and coordinated control activities in endemic countries.
A mathematical model suggests culling will not control the spread of white-nose syndrome, a deadly fungus threatening North American hibernating bats. The fungal pathogen occurs in caves and mines where bats live, making contact rates high among colonial bats.
Researchers found that using non-alcohol antibacterial mouthwash containing cetylpyridinium chloride (CPC) decreases the incidence of preterm birth. The study, funded by The Procter & Gamble Company, involved pregnant women with periodontal disease who received either treatment or a control group.
A new gene-spreading system has been proposed to control mosquito populations without pesticides. The system involves spreading disease-resisting genes in mosquito populations, rendering them infertile or killing females that mate with transgenic males.
The economic burden of dengue fever in the Western Hemisphere surpasses other viral illnesses, with estimated annual costs of $2.1 billion. Direct and indirect costs include ambulatory care, hospitalization, productivity losses, and government expenditures.
A study published in American Journal of Infection Control found that MRSA screening in ICUs can be cost-effective and save hospitals money. The research estimated that the screening could result in savings of almost $500 per hospital admission under optimal assumptions.
A study published in The Lancet Infectious Diseases found that malaria protection methods for pregnant women in sub-Saharan Africa are underutilized. Despite WHO policy, estimated coverage of intermittent preventive treatment (IPTp) is only 25% and insecticide-treated nets (ITNs) are used by just 17% of pregnant women at risk.
The Lancet series on health in Southeast Asia examines the region's diverse health systems, shifting disease burdens, and emerging infectious diseases. The series proposes increased regional cooperation for better maternal and child health outcomes.
A recent study evaluates integrated fruit production and organic fruit production systems for disease-resistant 'Liberty' apples. The research suggests that IFP could be widely implemented in the northeastern US, but OFP may be more feasible for small to midsized direct market operations due to higher costs.
A new study confirms that two doses of the varicella, or chickenpox, vaccine provide excellent protection in children against this highly contagious and, in some cases, severe disease. The study found that the effectiveness of two doses of vaccine was 98.3 percent in protecting against varicella, significantly higher than one dose.
A study by the Smoking Control Unit of the Catalan Institute of Oncology confirms that Europe's anti-tobacco laws have a direct effect on reducing tobacco consumption and passive smoke exposure. The European Union countries with stricter controls on smoking show lower consumption rates, particularly in the UK, Ireland, Malta, and Sweden.
Experts recommend stocking up on cholera vaccines to rapidly deploy to high-risk areas, complementing treatment efforts in Haiti. A ready supply could limit the impact of an outbreak and promote humanitarian benefits.
Research published in Thorax estimates that UK workplace asthma costs the country at least £100 million a year, with potentially as high as £135 million. The study reveals that the condition is underdiagnosed and that the employer should bear more responsibility for reducing exposure to agents causing workplace asthma.
A combination of increased domestic funding and foreign loans led to a dramatic increase in tuberculosis case finding in China. The study highlights the importance of evaluating the links between financing for health and TB control.
The Innovative Vector Control Consortium (IVCC) has received a $50 million grant to develop new insecticides for malaria and other neglected tropical diseases. The new funding will support the development of three new Active Ingredients for public health insecticides by 2020.
The European Network for Rare and Congenital Anaemia (ENERCA) aims to disseminate latest developments in rare anemias through a network of close contacts. The project has been funded with €1.2 million Euros by the European Commission, and Spain is working on developing a Strategic plan for rare diseases.