Articles tagged with Immune Response
A study found that the MDR1 gene variation is associated with immune recovery after HIV treatment. The polymorphism MDR1 3435C/T predicts improved CD4-cell count recovery. This suggests P-glycoprotein plays a crucial role in antiretroviral drug absorption.
Researchers at University of Pittsburgh identified Langerhans cell precursors that can be targeted to initiate or down-regulate the immune response, potentially leading to novel treatments for asthma and transplant rejection. The discovery could also enhance vaccine development.
Researchers found that bovine thrombin causes an immune response similar to lupus in mice and can lead to post-operative complications. Bovine thrombin is a potent enzyme used in surgical procedures, but its use should be restricted to life-saving surgeries due to the risk of autoimmune responses.
A study found that an oral immune-enhancing nutritional supplement improved preoperative host defence, reduced postoperative infections, and preserved renal function in elderly and high-risk patients undergoing elective coronary artery bypass. The supplement contained L-arginine, 3 polyunsaturated fatty acids, and yeast RNA.
Researchers found that minor mutations can significantly impair the immune system's ability to recognize and attack the virus. This means that vaccines targeting these regions may be less effective due to evolving strains of the virus.
A study by Penn researchers found that a common gene delivery system for muscular dystrophy can trigger an immune response in mice unless paired with a muscle-specific promoter. The use of restricted promoters is crucial before expanding clinical trials.
A new study from Penn State suggests that healthy eating habits and good health status can help maintain the ability to fight off germs and reduce illness in older adults. The research found that well-nourished women between 60 and 80 years old have immune systems that function similarly to younger women.
Researchers have identified a substance produced by the tuberculosis bacterium that triggers an immune response, suggesting it could enhance vaccine effectiveness. The substance, combined with vaccines, may push the body's immune system in the right direction to fight tuberculosis and other microbial infections.
Natural T cells are specialized cells that are part of white blood cells and help the body fight disease. Researchers at Penn State's College of Medicine have discovered that CD1d1 associates with glycolipids to transduce signals that 'turn-on' natural T cells, which helps the body fight disease.
Carnegie Mellon researcher Sheldon Cohen suggests that stress reduction may alter immune function, which could lead to better defenses against cancer. However, the evidence for this link is still incomplete, and more research is needed to confirm its validity.
Researchers are developing a new approach to treat cancer by boosting the immune system using dendritic cells, which can be grown in large quantities in culture. The therapy has shown promise in clinical trials, particularly for patients with advanced melanoma or breast cancer.