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March of Dimes calls for 50 percent reduction in preterm births by 2030

The March of Dimes aims to reduce US preterm birth rates to 5.5% by 2030 through evidence-based interventions such as eliminating early elective deliveries and optimizing birth spacing. The organization is also funding research to discover unknown causes of premature birth and identify new interventions.

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Scientists identify potential cause for 40 percent of pre-term births

Researchers at Queen Mary University of London discovered that stretching the amniotic membrane leads to the overproduction of prostaglandin E2, damaging tissue and reducing its mechanical properties. This overproduction activates a protein called connexin 43, potentially leading to rupture and pre-term birth.

US preterm birth rate drops to 15-year low

The US preterm birth rate has dropped to its lowest level in 15 years, but the country still earns a 'C' grade. Since 2006, about 176,000 fewer babies have been born too soon, potentially saving $9 billion in health and societal costs.

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US preterm birth rate shows 5-year improvement

The US preterm birth rate dropped for the fifth consecutive year in 2011 to 11.7 percent, giving thousands more babies a healthy start in life and saving billions in health and social costs. Four states earned an 'A' on the March of Dimes Premature Birth Report Card, while the US earned a 'C', despite progress.

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New research shows C-section not always best for babies

New research challenges conventional wisdom on C-sections for preterm babies, finding they may contribute to breathing problems. Small for gestational age babies delivered by c-section before 34 weeks had a 30 percent higher odds of developing respiratory distress syndrome than those born vaginally.

Pregnant women advised to stay cool for baby's sake

A QUT study found a link between temperature increases and the incidence of stillbirth and shorter pregnancies. The study, which recorded 101,870 births over four years, estimated that increased temperatures increase the risk of stillbirth by 15°C, with the lowest risks seen in the coolest weeks.

Pregnant mothers at risk from air pollution

A Californian-based study found traffic-related air pollution, particularly PAH, is linked to a 30% increase in premature births. Seasonal changes and proximity to the coast also affect pollutant concentrations.

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Drinking during pregnancy increases risk of premature birth

Researchers found drinking during early pregnancy increased risk of premature birth and low birth weight, while heavy drinkers were more likely to have unplanned pregnancies and very premature births. The study emphasized the need for improved detection of alcohol misuse in pregnancy.

New research helps explain how progesterone prevents preterm birth

Research led by Dr. Errol Norwitz found that progesterone prevents preterm labor by hindering apoptosis in fetal membranes, resulting in stronger and thicker fetal membranes. This study contributes to the understanding of what triggers labor and the role of progesterone in preventing premature birth.

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Preterm birth rates improve in most states

The US saw a two-year decline in preterm birth rates, primarily among babies born just weeks early, while many states improved in at least one contributing factor. The overall national rate remains high compared to top-scoring countries.

Incidence of cerebral palsy on rise in US

Researchers from Loyola University Health System found a link between premature births and cerebral palsy, with inflammation of the umbilical cord being a common complication. The study suggests that managing inflammation may reduce the risk of certain complications in these infants.

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Loss of 'guardian angel' gene prompts premature birth

A study by Cincinnati Children's Hospital Medical Center reveals that the loss of a 'guardian angel' gene leads to premature birth due to altered signaling pathways in the pregnant uterus. The findings could lead to new strategies for treating and preventing prematurity.

US gets a 'D' for preterm birth rate

The US received a 'D' grade on the March of Dimes Premature Birth Report Card, with over half a million newborns not receiving a healthy start. Seven states improved their preterm birth rates by reducing smoking, uninsured rates, and late preterm births.

More babies born prematurely but survival rates up, study shows

A 25-year study found premature births increased by nearly 10 times, yet survival rates more than halved, with a 10% reduction in stillbirths associated with pre-term births. Researchers attribute the findings to better understanding and medically induced early births.

Pre-pregnancy depressed mood may heighten risk for premature birth

Researchers found pre-pregnancy depressive mood may be a risk factor for premature birth among both blacks and whites, but the study did not establish cause and effect. Black women have nearly twice the odds of having a preterm birth compared to white women, potentially due to declining health over time.

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Study may pave way for treatments to delay early multiple births

A recent study published in The Lancet found that a treatment intended to prevent premature births in single pregnancies may be ineffective in women expecting twins. Researchers discovered an underlying difference between premature births in women with single and multiple pregnancies, which could inform improvements in treatment.

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Mothers launch national petition for preemies

The March of Dimes has launched a national petition to reduce the rate of premature birth, which affects over 530,000 babies each year. The four-point petition calls for hospitals to review cesarean-section births and inductions before 39 weeks gestation to prevent early deliveries.

World-first to predict premature births

A new computer program may reveal a way to predict premature birth with greater accuracy. The system, developed by Australian researchers and a pathology company, analyzes hormone levels to identify high-risk pregnancies.

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March of Dimes seeks answers to preterm birth

The March of Dimes has awarded $3.5 million to scientists studying the role of genes and heredity in premature births. The organization aims to understand the causes of preterm birth, which affects over half a million babies annually.

Premature births linked to physical abuse

A large-scale study published in the American Journal of Obstetrics & Gynecology found a strong link between physical abuse during pregnancy and premature births. Researchers surveyed 2660 Caucasian women and discovered that 24% of mothers of preterm newborns had experienced physical abuse, compared to 8% of those with term births.

Synchrotron radiation illuminates how babies' protective bubble bursts

A team of researchers from the University of Reading has developed a powerful X-ray beam technique to study the structure of amniotic membranes and their rupture. The findings reveal that the loss of a molecular lattice-like arrangement governs the timing of membrane rupture, paving the way for therapies to prevent premature birth.

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Low maternal cholesterol tied to premature birth

Research reveals that very low maternal cholesterol levels may increase the risk of premature birth and low birth weight, with no such link observed in African American women. Full-term babies born to mothers with low cholesterol also weighed less on average.

March of Dimes commits additional $3M to prematurity research

The March of Dimes has allocated $3 million to support eight scientists' research on predicting and preventing preterm birth. Five projects focus on immune responses, while others investigate the role of genetic factors, circadian rhythms, and potassium balance.

New study: Preterm birth causes one-third of all infant deaths

A new study published in Pediatrics found that preterm birth caused over one-third of infant deaths in the first year of life. The study used a new method to classify causes of infant death and found that premature birth was the leading cause, followed by birth defects.

March of Dimes: Drug to prevent preterm birth needs prompt FDA approval

A commercial progesterone therapy appears to prevent some premature births, with a 33% reduction in preterm birth rate for women who had a previous premature baby. The March of Dimes estimates that if all eligible women received the therapy, nearly 10,000 premature births might have been prevented.

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Researchers discover genetics markers to help predict risk for preterm birth

Two genetic markers, one associated with African American babies and the other with women with chronic hypertension, have been identified as potential predictors of preterm birth. The findings could lead to improved diagnosis, prevention, and treatment of preterm birth, reducing its risks for lifelong health complications.

March of Dimes urges federal legislation for IOM prematurity report

The March of Dimes calls for passage of federal PREEMIE Bill to address prematurity, with severe health consequences and significant economic burden estimated at over $26.2 billion annually. The organization supports increased research investment and public awareness campaigns to prevent premature birth.

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March of Dimes commits additional $2.4 million to prematurity research

The March of Dimes has awarded $2.4 million in grants to six innovative scientists working on new ways to identify women at increased risk for premature birth and understand the role of inflammation and progesterone in triggering labor. The goal is to prevent premature births, which are the leading cause of newborn death in the US.

Research on premature birth boosted with $10 Million NIH grant

The five-site network will identify genetic and environmental determinants of premature birth, utilizing advanced genomic technologies and statistical methods. The study's goal is to gain a deeper understanding of preterm births, a leading cause of infant mortality.

Prematurity experts call for targeted research

Premature birth is a complex disorder with no single cause, requiring a multi-faceted approach. Research in six promising areas may lead to new clinical strategies for identifying high-risk patients and preventing premature birth.

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Babies born at night have greater risk of death, study finds

A recent study published in Obstetrics & Gynecology found that babies born at night have a 12-16% increase in neonatal mortality, accounting for almost 10% of all neonatal deaths in California. This increased risk is attributed to various factors, including potential complications during delivery and reduced access to healthcare services.

Cancer drug could aid premature labour

A cancer drug has been found to control levels of a hormone receptor protein in the womb, which is linked with giving birth. The study, funded by Action Medical Research, aims to assess whether the drug can be used to prevent premature birth.

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Study finds markers for premature birth risk at the molecular level

A study published in American Journal of Obstetrics and Gynecology reveals that metabolic profiling can accurately identify patients at risk for preterm delivery. The method has shown a high degree of accuracy in identifying patients across different clinical groups, offering new hope for predicting the course of preterm labor.

Progesterone therapy could prevent thousands of preterm births

Researchers estimate that progesterone therapy could reduce the rate of recurrent preterm birth in the US by about 2%, preventing around 10,000 premature births annually. The study's findings are based on a clinical trial showing a significant reduction in preterm birth risk among women with a history of spontaneous preterm birth.

Outlook is bleak for the smallest premature babies: 80 percent have impairment

A new British study found that 41 percent of extremely premature babies have severe or moderate mental impairment at six years old. Only 20 percent have no neuromotor or mental disability. The March of Dimes emphasizes the importance of preventing prematurity, with a focus on research, education, and support for families.

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