Articles tagged with Premature Birth
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A new study has found that an inflammation-targeting antibody may improve preterm birth outcomes by reducing inflammatory signals in the placenta. The same antibody has also shown promise in preventing obesity-linked fatty liver disease, a condition that can progress to cirrhosis and liver cancer.
Researchers found that probiotics help preterm babies achieve a balanced gut microbiome and eradicate harmful bacteria. The study also shows that probiotic-supplemented preterm newborns have lower risk of carrying antimicrobial resistant bugs despite frequent antibiotic treatment.
A new study from the Stowers Institute for Medical Research reveals the placenta's polyploid cells play a vital role in supporting healthy embryonic development. The modified cell cycle controlling polyploidy is governed by the regulatory gene Myc, which supports DNA replication and prevents premature cellular aging.
Researchers at the University of Tsukuba found an association between evaporated alcohol from incubator disinfectants and alcohol absorption in premature infants. They introduced a new practice to reduce alcohol exposure, which was associated with decreased alcohol levels in infants' blood and air.
A new Dartmouth study reveals high rates of childbirth fear in US pregnant people, associated with factors such as racism, low income, and pre-existing conditions. The COVID-19 pandemic further exacerbated these fears, leading to increased stress and anxiety during labor.
Eight low-cost interventions can prevent an estimated 566,000 stillbirths and 5.2 million babies born preterm or small for gestational age each year. Implementing these interventions in 81 low- and middle-income countries could save the lives of millions of babies and improve long-term health outcomes.
A study published in Science Translational Medicine suggests that preterm infants' gut microbiomes play a role in the development of dangerous bacterial bloodstream infections. The researchers found that the most common bacteria causing these infections are also commonly found in the gut, and that antibiotics can disrupt the balance of...
A study of over 2.6 million people from Finland and Norway found that babies born preterm are more likely to develop asthma or chronic obstructive pulmonary disease (COPD) in adulthood. The risk was highest among those born extremely preterm, before 28 weeks of gestation.
A large-scale international study found that COVID-19 lockdowns led to a 3-4% reduction in preterm births worldwide, averting nearly 50,000 preterm pregnancies during the first month of lockdown. However, this decrease was limited to high-income countries, including Australia.
A Finnish study found that lowering alcohol prices led to a short-term increase in abortions and adverse birth outcomes, particularly among low-income women. Both factors returned to normal levels after several months. The research suggests that cheaper alcohol may lead to increased drinking and prenatal exposure to alcohol.
A UK program using magnesium sulfate to prevent cerebral palsy in premature babies has been shown to be both effective and cost-effective. The PReCePT program increased the use of magnesium sulfate by 9.5 percentage points on average, resulting in a lifetime saving of £3 million.
Researchers found that increasing arginase 1 availability helps alleviate unhealthy responses and interrupt destructive inflammation in diabetic retinopathy and retinopathy of prematurity. This is achieved by reducing L-arginine levels, which in turn reduces inducible nitric oxide synthase activity.
A study by RCSI University of Medicine and Health Sciences found that babies with lower birth weights are more likely to experience mental health problems in childhood and adolescence. The research used data from the Growing Up in Ireland study, following the same children repeatedly throughout their childhood and adolescence.
A new study published in PLOS ONE explores the relationship between preterm birth and educational attainment in U.K. children. The research found that children born before 32 weeks had higher rates of poor school attainment, but only those born very preterm remained at risk by the end of secondary school.
A pooled data analysis found that experience of race discrimination is associated with a heightened risk of premature birth and low birthweight. The study highlights the importance of addressing racism in healthcare to improve health outcomes for marginalized communities.
A new modeling study found that reducing excess prevalence of low birthweight, preterm birth, or small-for-gestational-age birth in low- and middle-income countries could lead to substantial long-term human capital gains. The study estimates potential gains of 20.3 million school years and $68.8 billion in lifetime income per birth coh...
A large-scale study of COVID-era birth data found a 6.5% decrease in premature births from cesarian and induced deliveries. The researchers believe this may be related to fewer prenatal visits during the pandemic. However, further research is needed to understand the impact on fetal health.
Researchers analyzed nearly 100,000 pregnancies and found no association between COVID-19 vaccination and poor birth outcomes. The study provides further evidence on the safety of mRNA vaccines for pregnant individuals.
A study of 383 extremely preterm babies found that most had neurodevelopmental disorders and/or other diagnoses during childhood. The children were referred for habilitation services and had a range of additional diagnoses, including asthma and short stature.
Researchers have discovered signature epigenetic biomarkers in mothers and fathers of preterm infants, which may lead to a non-invasive test to predict preterm birth. This could help prevent premature births and their related health impacts on infants.
A new study by researchers at the University of Copenhagen found that an imbalance in vaginal bacteria is associated with a higher risk of emergency caesarean section. The study analyzed 1,396 samples from 736 pregnant women and discovered that those with greater levels of imbalance were more likely to deliver via C-section.
A team of researchers has created a detailed map of the proteins in human lungs, shedding light on how the organs develop and function. The study found that the immune system in the lungs continues to mature after birth, providing new avenues for understanding diseases such as asthma and COVID-19.
A new smartphone app, MyHealthyPregnancy, evaluates preeclampsia risk and patient adherence to low-dose aspirin recommendations. The study found that 37% of high-risk patients were unaware they needed to take the medication, highlighting a need for improved communication between providers and patients.
New research from an international team of scientists found that poor timing of influenza vaccination campaigns in Brazil led to increased premature births, lower birth-weight babies, and the need for more cesarean sections. The study suggests that earlier flu vaccination campaigns could better protect pregnant women and their babies.
A study by researchers at Wayne State University found a dose-response relationship between SARS-CoV-2 severity and the risk of preterm birth, with severely infected mothers more likely to experience early birth. The study also linked severe COVID-19 infection to an increased risk of preeclampsia.
A systematic review found that azithromycin reduced low birth weight and prematurity in Africa and Asia but didn't lower infant deaths or hospital admissions. The study suggests the potential benefits of this intervention on neonatal outcomes may be limited, highlighting the need for further research.
Researchers at McGill University found that smoking during pregnancy is associated with an increased risk of premature birth, low birth weight, and birth defects. The study, which examined over nine million deliveries, also discovered that smoking mildly decreases the risk of preeclampsia.
A study by the University of Geneva found that maternal voice significantly reduces signs of pain in premature babies during medical interventions. The presence of a mother's voice also increases oxytocin levels, indicating better pain management.
A Stanford University study suggests that wildfire smoke exposure during pregnancy increases the risk of preterm birth, with as many as 7,000 extra births attributed to this factor between 2007 and 2012. The research highlights the need for investment in prescribed burns, mechanical thinning, or other efforts to reduce extreme wildfires.
A traditional vegetable diet rich in antioxidants and anti-inflammatory nutrients can lower the risk of premature birth. Consuming high amounts of carrots, cauliflower, broccoli, and other vegetables before conception helps women reach full term pregnancy.
Researchers found that women who deliver prematurely have a more diverse vaginal microbiome, especially in the first trimester. This link highlights specific bacteria associated with premature birth, which could aid future diagnostic and therapeutic strategies.
Children born to mothers with eating disorders face increased risks of premature birth, microcephaly, and hyperemesis during pregnancy. The study also found that the risk varies depending on the type of eating disorder and whether the mother has an active or previous eating disorder.
A study published in The BMJ found that China's universal two-child policy resulted in an additional 5.4 million births, with a significant increase in births to older mothers and multiparous mothers. However, the policy's impact on premature births was not significantly increased.
A UW study found that moving to a new home during the first three months of pregnancy increases the risk of low birthweight, premature birth, and smaller-than-expected babies. Despite limitations, the researchers suggest counseling patients on stress-mitigating techniques and care continuity may be beneficial.
Research finds that moving house during early pregnancy increases the risk of low birthweight and premature birth, as well as smaller than expected size babies. The study analyzed data from over 30,000 women in Washington state, USA, between 2007 and 2014.
A new Cochrane review finds that increasing omega-3 intake during pregnancy reduces the risk of premature births by 11% and early premature births by 42%. The optimal dose is a daily supplement containing between 500 and 1000mg of long-chain omega-3 fats starting at 12 weeks of pregnancy.
Researchers at University of Connecticut have discovered a potential treatment for premature birth by targeting the immune system. Studies in mice suggest that inhibiting granulocyte-macrophage colony-stimulating factor (GM-CSF) could prevent preterm labor and birth.
Early premature birth at less than 34 weeks was associated with increased risk of symptoms of attention-deficit/hyperactivity disorder (ADHD) in children. The association was most pronounced among girls, suggesting a potential link between prematurity and ADHD symptoms that may be influenced by genetic and environmental factors.
A new blood test identified biomarkers in maternal blood that accurately predicted gestational age and preterm delivery, which may help doctors assess pregnancies more effectively. The study's findings offer hope for preventing premature birth, a crisis affecting millions of babies worldwide each year.
A Stanford-led study developed a blood test detecting premature birth with 75-80% accuracy. The test also estimates gestational age, reducing infant mortality risk and improving prenatal care in low-resource settings.
A study found that premature birth impacts brain function in infants, particularly in the frontal lobe, which is crucial for cognitive development. The research used EEG signals to measure functional networks in infant brains, revealing selective effects on cognitive functions.
A study found a strong correlation between midwife integration and better birth outcomes, with higher rates of vaginal births and breastfeeding. States with high midwife integration, such as Washington and Oregon, had lower rates of premature births, cesarean deliveries, and newborn deaths.
A new U.S.-wide report card ranks all 50 states on their maternity care quality, revealing a strong connection between midwifery integration and improved birth outcomes. States with high midwifery integration scores tend to have lower rates of premature births, cesarean deliveries, and newborn deaths.
Observational research suggests that probiotic intake during late pregnancy may lower the risk of pre-eclampsia and premature birth. A significant association was found between probiotic consumption and a 20% lower risk of pre-eclampsia, while an 11% lower risk was observed for premature birth during early pregnancy.
A review of high-quality observational studies found that drinking up to four units a week during pregnancy was associated with an 8% higher risk of having a small baby. The researchers conclude that the evidence is sparse, and guidance should advise abstention as a precautionary principle.
A new study by Ben-Gurion University researchers found that pregnant women with a family history of premature births are at higher risk of preterm delivery. The study followed 2,300 mothers and daughters over 22 years and found that the risk was significantly higher among those whose mothers had given birth early in their pregnancies.
A new study reveals that certain bacteria in the cervix and vagina may increase or decrease the risk of premature birth. Researchers found that some species, such as bifidobacterium and lactobacillus, lower the risk, while others, like anaerobic bacteria, significantly increase it.
A study of 2,000 pregnant women found that certain bacterial species in the cervix were associated with a lower risk of preterm birth, while others increased the risk. The findings offer new hope for preventing prematurity and its devastating consequences.
A new study identifies calciprotein particles as a culprit in premature birth, a leading cause of infant death and disability. The research suggests therapies or dietary supplements blocking these particle formations could prevent preterm birth.
Research suggests strenuous exercise has no significant impact on labor duration or risk of premature birth. Exercise is found to reduce excessive birthweight and lower the risk of C-section births. However, more research is needed in elite athletes to fully understand its effects during pregnancy.
Researchers at Imperial College London found a significant association between thicker cervical stitch threads and increased rates of premature birth and intrauterine death. The study suggests that switching to thinner threads could prevent up to 170,000 premature births globally every year.
A new study by NYU Langone Health reveals that air pollution in the US is responsible for approximately 3% of premature births, with a total economic cost of $4.33 billion annually. The majority of these births occur in urban counties, primarily in Southern California and the Eastern U.S.
The US earns a 'C' grade for its preterm birth rate, with racial and ethnic disparities persisting in many states. Cities like Portland, Oregon, and St. Paul, Minnesota, have lower rates, while Shreveport, Louisiana, has the highest rate among major cities.
Researchers found early ultrasound signs of water absorption changes in cervix before delivery, indicating potential preterm birth risk. Current cervical length measurement methods are limited in their usefulness.
A proof-of-concept study suggests using ultrasound to detect cervical stiffness changes that indicate an increased risk of preterm labor. Researchers found patients between 24 and 35 weeks pregnant with below-average cervical stiffness were at higher risk of preterm birth.
Scientists investigate placental microbiome, genes, and uterine muscle cells to understand preterm labor triggers. The goal is to develop novel drugs and treatments to prevent premature birth.
A new study by King's College London found that premature birth alters the connections between key areas of the brain. This can lead to difficulties in learning, concentration, and social skills later in childhood.
Preterm birth is now the world's number one killer of young children, accounting for nearly 1.1 million deaths in 2013. Direct complications from preterm births killed an additional 125,000 children between one month and five years old.
The national preterm birth rate fell to 11.4% in 2013, beating the federal Healthy People 2020 goal seven years ahead of schedule. Despite this progress, the US still ranks among high resource countries with one of the highest preterm birth rates.
The March of Dimes aims to reduce US preterm birth rates to 5.5% by 2030 through evidence-based interventions such as eliminating early elective deliveries and optimizing birth spacing. The organization is also funding research to discover unknown causes of premature birth and identify new interventions.