A study by Columbia University Irving Medical Center reveals that inner-city asthma patients often rely on emergency rooms due to insufficient disease management. The research highlights the urgent need for comprehensive asthma intervention in Harlem, targeting community health workers to educate and support patients.
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A new study found that consuming high levels of antioxidants like beta carotene, selenium, and vitamins C and E can significantly improve lung function, comparable to the difference between a nonsmoker and a long-term smoker. The research suggests that these antioxidants may help prevent asthma, emphysema, and chronic bronchitis.
Researchers at Johns Hopkins found that deep breaths can relax lung muscles and reduce wheezing in non-asthmatics by up to 80%. However, asthmatic patients showed minimal improvement from taking deep breaths before exposure to a contracting drug. This new finding could lead to the development of new asthma treatments.
Duke researchers have identified a lung condition in breast cancer patients that can limit therapy choices if not treated promptly. The disorder, DPTS, is successfully treated with inexpensive corticosteroids, improving pulmonary function by 17%.
A two-year study found that moderate air pollution can decrease lung function in adult hikers, even at relatively low ozone concentrations. Hikers with a history of asthma or wheezing experienced more pronounced declines.
Researchers at University at Buffalo found a miniscule increase in free radicals in the blood reflects lung damage equivalent to 3-5 years of aging. Oxidative stress was also associated with narrowing of pulmonary airways, while bilirubin showed a positive relationship to lung function.
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A national trial is underway to determine the effectiveness of removing portions of lungs in patients with severe emphysema. The study aims to find out if the procedure improves long-term outcomes and reduces complications for patients with this debilitating disease.
A recent study suggests that a human gene variation affecting lung enzyme production may be associated with reduced susceptibility to lung cancer. The study found that approximately 8% of the population has the 'protective' gene form, which reduces by about 54% the risk of developing lung cancer among smokers.
Scientists found that mice lacking the macrophage elastase enzyme showed no signs of emphysema after heavy smoking. This discovery challenges previous theories and offers new hope for emphysema treatment. Researchers are now exploring metalloproteinase inhibitors to prevent the disease.
Researchers at the University of Pittsburgh Cancer Institute have found a biological switch that drives the growth of lung cells in ex-smokers, leading to an increased risk of lung cancer. The 'switch' is triggered by gastrin-releasing peptide (GRP) receptors, which capture circulating hormones and spur lung cell division.
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Researchers at National Jewish Health will investigate the basic mechanisms of fibrosis and develop clinical trials to limit fibrotic response. Four interstitial lung disease research projects are underway, focusing on inflammation, growth factors, and cellular interactions.
Scientists at Johns Hopkins Medicine have found a natural antimicrobial compound called hTAP that appears to be disabled in CF patients, increasing their vulnerability to lung infections. The researchers believe mass-producing similar compounds could help fight lung infections in both CF patients and the general population.
A major seven-year national study will evaluate the safety and effectiveness of lung volume reduction surgery for people with severe emphysema. Patients selected for the surgery will undergo evaluation and medical therapy at either University of Maryland Medical Center or Johns Hopkins Hospital.
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The NHLBI and HCFA have announced a clinical trial to evaluate the safety and effectiveness of lung volume reduction surgery (LVRS) for patients with emphysema. The study aims to determine whether LVRS is a viable treatment option for this population, which currently has limited treatment options.
A temporary metal filter successfully caught a life-threatening blood clot in a bedridden patient, preventing catastrophic lung damage. The procedure, performed by Johns Hopkins physicians, marks the first use of the filter in the US and holds potential for thousands of accident victims.
Researchers at Northwestern University have developed an implantable artificial lung that preserves lung function for 24 hours in animal models. The device is intended as a 'bridge to transplant' for patients awaiting lung transplants and as treatment for acute lung failure.
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A five-center trial shows partial liquid ventilation is safe and effective, improving lung function and increasing survival chances for critically ill premature infants. The procedure involves introducing oxygen-rich liquid into the lungs, reducing pressure damage and improving oxygen exchange.