Articles tagged with Skin
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A recent study published in Infection Control and Hospital Epidemiology found that iodine-based skin preparation solutions, such as 3M's DuraPrep Surgical Solution, may be superior to chlorhexidine in preventing surgical-site infections. The study of over 3,200 general surgery patients suggests a significant reduction in morbidity and ...
A study of 320 patients found heparin-induced skin lesions in 7.5% of cases, mostly due to delayed-type hypersensitivity response. Pregnancy, obesity, and long treatment duration increased the risk of such reactions.
A new study reveals that vitamin C helps promote wound healing and protects skin cells from DNA damage, a finding with great relevance to the cosmetics industry. The research also suggests that vitamin C can help remove DNA damage caused by free radicals, leading to potential advances in skin regeneration and cancer prevention.
Scientists have identified a gene mutation responsible for premature skin aging, known as 'wrinkly skin syndrome.' Increasing levels of the PYCR1 protein could reverse conditions causing fast aging and wrinkly skin.
Research found that psoriasis patients have weaker brain response to disgusted faces, indicating a potential coping strategy to protect against social stigma. The study suggests that this adaptation may also apply to other stigmatizing skin conditions like acne or scarring.
A study found that dermatologists detected 56.3% of all melanomas and 60% of in situ melanomas, compared to 54.5% for patient-detected cases. Dermatologist detection was also associated with thinner melanomas, with median depths of 0.33mm for physician-detected cases versus 0.55mm for patient-detected cases.
A study characterizes eczema patients most at risk for serious viral infections, including herpes simplex and vaccinia viruses. The research highlights the importance of skin-barrier defects and antimicrobial protein production in increasing susceptibility to these infections.
The Human Microbiome Project is expanding its efforts to understand the relationship between the microbiome and human health. The NIH has awarded over $42 million to fund sequencing centers and disease projects, including studies on psoriasis, bacterial vaginosis, obesity, and Crohn's disease.
Researchers found that applying a chemotherapy medication to the face reduced actinic keratoses by 87% and improved signs of aging. The treatment also showed promise in addressing photo-aging, with patients reporting improved skin appearance and willingness to undergo therapy again.
Researchers have found that CSA-13, a synthetic compound, can kill vaccinia virus in cell cultures and mice, while also stimulating the innate immune system. The study showed that CSA-13 reduced skin lesions caused by vaccinia virus in infected mice.
A recent study published in Science reveals that the skin microbiome is much more diverse than previously thought, with varying levels of bacteria at different body sites. The research found that dry and moist skin had a broader variety of microbes than oily skin, and that certain skin areas were more stable over time.
Scientists identify distinct subsets of pain-sensing neurons responsible for detecting heat and mechanical pain, challenging conventional wisdom that the brain disentangles these sensations. The study's findings have potential implications for understanding and treating conditions like diabetic neuropathy.
A web-based system allowing general practitioners to confer with specialists about skin conditions has been shown to reduce referrals to dermatologists by approximately 20%. The study found that in-person consultations were preventable for 39% of patients who received teledermatologic consultations, compared to 18.3% in the control group.
Scientists discovered that a substance secreted by damaged skin can trigger asthmatic symptoms in mice exposed to eczema-causing agents. Early treatment of skin rash and inhibition of the trigger substance may block asthma development in young patients with eczema.
A study found that Asian Americans who adopted more aspects of Western culture were more likely to engage in sun exposure behaviors, such as deliberate sunbathing and getting more sun on weekends. This association may lead to increased risk of skin cancer among this population.
Scientists at Washington University School of Medicine discovered a substance called TSLP, which is secreted by damaged skin and circulates through the body to trigger asthmatic symptoms. Early treatment of skin rash and inhibition of TSLP production may block asthma development in young patients with eczema.
Researchers at Karolinska Institutet discovered tufted bacteria can attach to premature babies' skin, causing infection. The bacteria's unique hair-like structures facilitate adhesion, while LL37 antimicrobial peptide helps inhibit growth.
A clinical trial conducted by the University of Manchester found that No7 Protect & Perfect Intense Beauty Serum can clinically reduce wrinkles and improve sun-damaged skin. The study, which tested 60 volunteers, showed a significant improvement in facial wrinkles after 12 months of daily use.
Researchers at Northwestern University have discovered a powerful relief for kids' chronic eczema using diluted beach baths. The study found that giving pediatric patients with moderate or severe eczema reduced signs of infection and improved the severity and extent of the eczema on their bodies.
A new delivery method of flu vaccine using microneedle skin patches has shown comparable effectiveness to conventional intramuscular injections. The patch-based approach eliminates pain, increases convenience and could lead to improved seasonal vaccination coverage.
Researchers discovered an antioxidant, ellagic acid, which prevents collagen destruction and inflammatory response in human skin cells and mice exposed to UV-B. The study found that ellagic acid reduces MMP secretion and inflammation, demonstrating its potential to prevent wrinkle formation and photo-aging.
Researchers found carotenoids produced in the liver of Common Crossbills, contradicting previous assumptions about skin synthesis. The discovery highlights inter-specific variation in mechanisms of color production, shedding light on evolutionary pathways involved in color signaling.
Researchers found that avotermin improved scar appearance by an average of five points at six months and eight points by month 12 in two studies. The treatment also showed a significant improvement in the structure of healed skin, with 60% of scars demonstrating less abnormal collagen fibre orientation.
CTIP2 is a transcriptional factor controlling skin development and lipid biosynthesis, potentially playing a role in skin disorders and wrinkling. Understanding its mechanisms may provide a solution to these issues.
A new web-based therapy programme, eTIPS, is being tested to help people with psoriasis manage their condition better. The programme uses cognitive behaviour therapy to address the psychological discomfort caused by the visible nature of the condition.
A new study finds that Albolene moisturizing cleanser is as effective as a prescription moisturizer in reducing dryness, scaling, and itching related to mild to moderate eczema. The study suggests that over-the-counter moisturizers can be a cost-effective alternative for treating eczema without a prescription.
Burn rehabilitation experts at UT Southwestern recommend a hierarchy of treatment strategies to alleviate chronic itching caused by burn scars. Topical creams and ointments are often effective, while oral antihistamines may be necessary for more severe cases. Other non-medicinal treatments like lasers and massage can also provide relief.
A study of 170 military personnel who were evacuated from combat zones found that 34% were diagnosed with dermatitis or general skin inflammation. The study highlights the importance of identifying individuals with chronic skin conditions before deployment to reduce evacuations and improve combat effectiveness.
Gladstone scientists discovered that the DGAT1 enzyme plays a crucial role in regulating retinoic acid levels in the skin. Mice lacking this enzyme experienced increased retinoic acid levels, leading to skin sensitivity and hair loss, which could be prevented by restricting retinol intake.
Researchers found that ustekinumab significantly improves symptoms of psoriatic arthritis and diminishes skin lesions in patients. The treatment, which targets interleukins 12 and 23, showed good tolerability and a benign safety profile.
A research team developed an autologous full-thickness oral substitute that mimics the characteristics of gingiva, providing a promising solution for oral cavity reconstruction. The study's results support the need for larger clinical trials to further evaluate the effectiveness of this new tissue-engineered product.
Natural aromatic oils can trigger allergic reactions, according to a study by Lina Hagvall at the University of Gothenburg. The research found that common perfume substances, like geraniol and lavender oil, can become allergens through autoxidation and skin enzyme reactions.
A modeling study reveals that Katrina-flooded homes can harbor hazardous contaminants in the air, posing significant health risks to residents and first responders. The study identifies inhalation exposure routes through volatile and semi-volatile organic pollutants, highlighting the need for better preparation and safety protocols.
A pre-emptive skin regimen can significantly reduce skin-associated toxicities associated with panitumumab for metastatic colorectal cancer treatment. The study found that this approach reduced the incidence of grade 2 or higher skin toxicities by over 50%. Patients who received prophylactic treatment reported improved quality of life,...
Researchers at UT School of Public Health found a strong link between PVL and severe CA MRSA infections. Using animal models, they identified PVL as a potential vaccine target against these deadly strains.
Researchers found that photodynamic therapy, combining a topical photosensitizer and laser treatment, increases collagen levels and produces other skin changes in sun-damaged skin. The treatment may be particularly effective for skin with severe sun damage.
A study found that oral vitamin D supplements increased cathelicidin production in the skin of patients with atopic dermatitis, a common form of eczema. This increase helped to correct a defect in the immune system and reduce the risk of skin infections.
Researchers have found that nanoparticles can pass through human skin, especially when damaged, raising concerns about their safety. The study, led by Dr. Lisa DeLouise, used mice as a model and showed that nanoparticles accumulate in skin folds and around hair follicles.
Researchers at the University of Nebraska-Lincoln found that people who react strongly to threatening visual images and sounds tend to support public policies protecting society over individual privacy. This study controlled for factors like gender, age, and income, suggesting a link between biology and political opinions.
Topical estradiol application stimulates collagen production in sun-protected skin of older men and women, but not in sun-exposed areas like the face or arms. This study found that natural aging and photo-aging share biochemical features, including a reduction in collagen, which is essential for maintaining skin's inner layer structure.
A genetic mutation in the filaggrin gene increases the risk of developing atopic dermatitis by threefold, while also predisposing individuals to hay fever and asthma. The study found that nearly 8% of German school children carry this genetic variation.
Researchers found that UVA1 phototherapy is effective for patients with morphea and related diseases regardless of skin type. The study analyzed over 100 patients and showed no significant correlation between skin type and clinical improvement scores.
Researchers found that a natural lipid, phosphatidylserine, can prevent collagen reduction and increase MMPs in both natural and UV-induced aging. Topical application of the molecule may be a simple way to slow down skin wrinkling.
Researchers at the University of Minnesota have developed a new standard of care for children with recessive dystrophic epidermolysis bullosa (RDEB) using cord blood and bone marrow transplants. The treatment has shown promising results in improving skin quality and reducing blisters, offering new hope for these patients.
Researchers discovered a molecular alarm system in the skin that detects defects and triggers an immune response, leading to potentially harmful effects. The study found that genetic abnormalities in the skin can lead to an overproduction of white blood cells, which can be life-threatening.
Researchers found a common core skin microbiome in healthy individuals, dominated by Proteobacteria species. The study establishes the basis for determining a core microbiome, which may hold the key to novel treatments for skin conditions like acne and atopic dermatitis.
Regular skin self-exams can help couples detect melanoma earlier, increasing their chances of survival. Couples with strong bonds are more likely to perform these exams and support each other through the process.
A new study presented at the Experimental Biology Annual Meeting shows that Dermytol produces a significant reduction in malignant melanoma cell growth. The compound has demonstrated potential in reducing damage to skin cells and may be used in anti-aging and sun-protection products.
Researchers found that snakes in some areas have developed extreme resistance to tetrodotoxin, a toxin produced by poisonous newts. This means that the newts' toxicity levels are no longer effective against these snakes, allowing them to thrive and even dominate the populations.
Research at the University of Bath found that acne sufferers are less likely to participate in sport or exercise due to skin anxiety, leading to lower self-esteem and a poorer quality of life. The study aims to develop new ways to encourage acne sufferers to stay physically active.
A new injectable drug, etanercept, has been shown to dramatically reduce psoriasis flare-ups in pediatric patients. The study found that 57% of patients achieved a 75% or greater improvement in symptoms, compared to 11% on placebo.
Patients with severe psoriasis have a 50% higher risk of death compared to those without the condition. The study found that men and women with severe psoriasis died an average of 3.5 and 4.4 years earlier, respectively.
Researchers at Stanford University School of Medicine have reversed the effects of aging on the skin of mice by blocking the action of a single critical protein, NF-kappa-B. The study's findings suggest that genetic changes contributing to aging can be reversed even late in life.
Four distinct skin disorders were found in construction workers who helped repair buildings after Hurricane Katrina and Hurricane Rita. These disorders affected 42.6% of the workers, with papular urticaria being the most common, followed by bacterial folliculitis and fiberglass dermatitis.
The collaboration aims to separate skin layers, decontaminate tissue, and speed up tissue cleaning using the Raydiance USP laser platform. This project has the potential to increase the supply of dermal tissues, resulting in better outcomes for more patients.
Researchers have successfully sequenced the complete genome of Malassezia globosa, a naturally occurring fungus responsible for dandruff and other skin conditions. The genetic make-up of M. globosa has expanded treatment targets from a few observational characteristics to over 4,000 molecular targets.
The NHS spends £16 million a year on specialized bath products for eczema, despite lack of evidence showing their effectiveness. Healthcare professionals often recommend them to patients, but experts disagree on their value.
Researchers at Massachusetts General Hospital found a strong association between exposure to gadolinium-containing contrast agents and the development of nephrogenic systemic fibrosis (NSF) in kidney failure patients. The study also showed that individuals with NSF had a significantly increased risk of dying within two years.
A new study published in Arthritis & Rheumatism found that patients with kidney failure who develop nephrogenic systemic fibrosis (NSF) have a significantly higher risk of dying. Gadolinium exposure is identified as a significant risk factor for developing NSF.
Researchers found that an enzyme called transglutaminase-2 (TG2) may be involved in the development of nephrogenic systemic fibrosis (NSF), a rare tightening and swelling of the skin and organs. The study suggests a potential strategy for preventing or treating NSF using drugs that inhibit TG-2 activation.