Articles tagged with Skin
Researchers will investigate why atopic dermatitis patients are susceptible to staph and other bacterial and viral infections, and evaluate the effectiveness of vitamin D in reducing or preventing staph colonization. The study aims to contain drug-resistant MRSA infections and widespread viral skin infections.
Researchers found desert-living bats have reduced cutaneous water loss compared to non-desert species, with a potential mechanism involving lipid composition adjustments. This adaptation could provide significant insight into how bats cope with future climate changes.
Scientists developed a fast, simple and inexpensive test for detecting chemicals that cause contact dermatitis, eliminating the need for animal testing. The test uses nitrobenzenethiol as a skin protein surrogate, producing positive results for known skin irritants and negative results for non-irritating substances.
A University of Illinois study found that a specific omega-6 fatty acid is critical for maintaining healthy skin. Without this acid, mice developed severe ulcerative dermatitis, which was reversed when the acid was added to their diet.
Researchers from P&G Beauty & Grooming present studies on skin care science, including the impact of hexamidine on stratum corneum lipid metabolism pathways and its potential to restore aging skin's barrier function. Eleven posters will be displayed at the AAD Annual Meeting showcasing diverse research topics.
Researchers have identified five cases of toilet-seat dermatitis, a skin condition that can be caused by wooden toilet seats or exposure to harsh cleaning chemicals. The study recommends using paper toilet seat covers, replacing wooden seats with plastic ones, and avoiding harsh cleaners to prevent the condition.
Researchers at Albert Einstein College of Medicine developed a new approach to treat and heal skin abscesses caused by antibiotic-resistant staph bacteria using nitric oxide-releasing nanoparticles. The therapy was shown to clear up infections and promote healing in mice, offering a potential breakthrough in treating MRSA infections.
Researchers used high-frequency ultrasound with elastography to identify skin cancer with high accuracy, distinguishing between malignant and benign lesions by measuring their elasticity. This non-invasive procedure can aid physicians in treatment and reduce the number of unnecessary biopsies of benign skin lesions.
A three-year study in remote communities found a significant reduction in skin sores among Aboriginal children, with over 6000 assessments conducted on nearly 2500 children. The program's success highlights the importance of local education and treatment, but ongoing efforts are needed to address underlying causes such as poor housing ...
Researchers at Helmholtz Munich have discovered Th22 cells, a previously unknown subset of T helper cells that aid in tissue repair and prevent inflammation. The newly found cells hold promise for developing new treatment methods for inflammatory skin diseases and potentially also allergic respiratory diseases.
A Tel Aviv University-developed dressing can eradicate infection-causing bacteria after just two days, protecting wounds until they heal. The biodegradable, antibiotic-infused material mimics skin's protective properties and helps doctors administer high doses of antibiotics locally, reducing toxicity issues.
A recent study published in the Journal of Rheumatology has found a clear link between smoking and skin problems in people with systemic lupus erythematosus (SLE). The study, led by Dr. Christian A Pineau, reveals that smokers are at higher risk for skin damage, including permanent hair loss and scarring from skin inflammation.
Researchers have discovered a connection between gene expression and the development of lung disease in scleroderma patients. The study suggests that a specific gene profile may predict which individuals are at risk of developing lung complications, providing potential targets for new treatments.
Researchers found that aggressive microdermabrasion using a coarse diamond-studded instrument induced molecular changes in the skin of older adults, similar to those seen during wound healing. This procedure mimicked natural skin remodeling processes and increased collagen production.
A recent study published in Infection Control and Hospital Epidemiology found that iodine-based skin preparation solutions, such as 3M's DuraPrep Surgical Solution, may be superior to chlorhexidine in preventing surgical-site infections. The study of over 3,200 general surgery patients suggests a significant reduction in morbidity and ...
A study of 320 patients found heparin-induced skin lesions in 7.5% of cases, mostly due to delayed-type hypersensitivity response. Pregnancy, obesity, and long treatment duration increased the risk of such reactions.
A new study reveals that vitamin C helps promote wound healing and protects skin cells from DNA damage, a finding with great relevance to the cosmetics industry. The research also suggests that vitamin C can help remove DNA damage caused by free radicals, leading to potential advances in skin regeneration and cancer prevention.
Scientists have identified a gene mutation responsible for premature skin aging, known as 'wrinkly skin syndrome.' Increasing levels of the PYCR1 protein could reverse conditions causing fast aging and wrinkly skin.
Research found that psoriasis patients have weaker brain response to disgusted faces, indicating a potential coping strategy to protect against social stigma. The study suggests that this adaptation may also apply to other stigmatizing skin conditions like acne or scarring.
A study found that dermatologists detected 56.3% of all melanomas and 60% of in situ melanomas, compared to 54.5% for patient-detected cases. Dermatologist detection was also associated with thinner melanomas, with median depths of 0.33mm for physician-detected cases versus 0.55mm for patient-detected cases.
A study characterizes eczema patients most at risk for serious viral infections, including herpes simplex and vaccinia viruses. The research highlights the importance of skin-barrier defects and antimicrobial protein production in increasing susceptibility to these infections.
The Human Microbiome Project is expanding its efforts to understand the relationship between the microbiome and human health. The NIH has awarded over $42 million to fund sequencing centers and disease projects, including studies on psoriasis, bacterial vaginosis, obesity, and Crohn's disease.
Researchers found that applying a chemotherapy medication to the face reduced actinic keratoses by 87% and improved signs of aging. The treatment also showed promise in addressing photo-aging, with patients reporting improved skin appearance and willingness to undergo therapy again.
Researchers have found that CSA-13, a synthetic compound, can kill vaccinia virus in cell cultures and mice, while also stimulating the innate immune system. The study showed that CSA-13 reduced skin lesions caused by vaccinia virus in infected mice.
A recent study published in Science reveals that the skin microbiome is much more diverse than previously thought, with varying levels of bacteria at different body sites. The research found that dry and moist skin had a broader variety of microbes than oily skin, and that certain skin areas were more stable over time.
Scientists identify distinct subsets of pain-sensing neurons responsible for detecting heat and mechanical pain, challenging conventional wisdom that the brain disentangles these sensations. The study's findings have potential implications for understanding and treating conditions like diabetic neuropathy.
Scientists at Washington University School of Medicine discovered a substance called TSLP, which is secreted by damaged skin and circulates through the body to trigger asthmatic symptoms. Early treatment of skin rash and inhibition of TSLP production may block asthma development in young patients with eczema.
A web-based system allowing general practitioners to confer with specialists about skin conditions has been shown to reduce referrals to dermatologists by approximately 20%. The study found that in-person consultations were preventable for 39% of patients who received teledermatologic consultations, compared to 18.3% in the control group.
Scientists discovered that a substance secreted by damaged skin can trigger asthmatic symptoms in mice exposed to eczema-causing agents. Early treatment of skin rash and inhibition of the trigger substance may block asthma development in young patients with eczema.
A study found that Asian Americans who adopted more aspects of Western culture were more likely to engage in sun exposure behaviors, such as deliberate sunbathing and getting more sun on weekends. This association may lead to increased risk of skin cancer among this population.
Researchers at Karolinska Institutet discovered tufted bacteria can attach to premature babies' skin, causing infection. The bacteria's unique hair-like structures facilitate adhesion, while LL37 antimicrobial peptide helps inhibit growth.
A clinical trial conducted by the University of Manchester found that No7 Protect & Perfect Intense Beauty Serum can clinically reduce wrinkles and improve sun-damaged skin. The study, which tested 60 volunteers, showed a significant improvement in facial wrinkles after 12 months of daily use.
A new delivery method of flu vaccine using microneedle skin patches has shown comparable effectiveness to conventional intramuscular injections. The patch-based approach eliminates pain, increases convenience and could lead to improved seasonal vaccination coverage.
Researchers at Northwestern University have discovered a powerful relief for kids' chronic eczema using diluted beach baths. The study found that giving pediatric patients with moderate or severe eczema reduced signs of infection and improved the severity and extent of the eczema on their bodies.
Researchers discovered an antioxidant, ellagic acid, which prevents collagen destruction and inflammatory response in human skin cells and mice exposed to UV-B. The study found that ellagic acid reduces MMP secretion and inflammation, demonstrating its potential to prevent wrinkle formation and photo-aging.
Researchers found carotenoids produced in the liver of Common Crossbills, contradicting previous assumptions about skin synthesis. The discovery highlights inter-specific variation in mechanisms of color production, shedding light on evolutionary pathways involved in color signaling.
Researchers found that avotermin improved scar appearance by an average of five points at six months and eight points by month 12 in two studies. The treatment also showed a significant improvement in the structure of healed skin, with 60% of scars demonstrating less abnormal collagen fibre orientation.
CTIP2 is a transcriptional factor controlling skin development and lipid biosynthesis, potentially playing a role in skin disorders and wrinkling. Understanding its mechanisms may provide a solution to these issues.
A new web-based therapy programme, eTIPS, is being tested to help people with psoriasis manage their condition better. The programme uses cognitive behaviour therapy to address the psychological discomfort caused by the visible nature of the condition.
A new study finds that Albolene moisturizing cleanser is as effective as a prescription moisturizer in reducing dryness, scaling, and itching related to mild to moderate eczema. The study suggests that over-the-counter moisturizers can be a cost-effective alternative for treating eczema without a prescription.
Burn rehabilitation experts at UT Southwestern recommend a hierarchy of treatment strategies to alleviate chronic itching caused by burn scars. Topical creams and ointments are often effective, while oral antihistamines may be necessary for more severe cases. Other non-medicinal treatments like lasers and massage can also provide relief.
A study of 170 military personnel who were evacuated from combat zones found that 34% were diagnosed with dermatitis or general skin inflammation. The study highlights the importance of identifying individuals with chronic skin conditions before deployment to reduce evacuations and improve combat effectiveness.
Gladstone scientists discovered that the DGAT1 enzyme plays a crucial role in regulating retinoic acid levels in the skin. Mice lacking this enzyme experienced increased retinoic acid levels, leading to skin sensitivity and hair loss, which could be prevented by restricting retinol intake.
Researchers found that ustekinumab significantly improves symptoms of psoriatic arthritis and diminishes skin lesions in patients. The treatment, which targets interleukins 12 and 23, showed good tolerability and a benign safety profile.
Natural aromatic oils can trigger allergic reactions, according to a study by Lina Hagvall at the University of Gothenburg. The research found that common perfume substances, like geraniol and lavender oil, can become allergens through autoxidation and skin enzyme reactions.
A research team developed an autologous full-thickness oral substitute that mimics the characteristics of gingiva, providing a promising solution for oral cavity reconstruction. The study's results support the need for larger clinical trials to further evaluate the effectiveness of this new tissue-engineered product.
A modeling study reveals that Katrina-flooded homes can harbor hazardous contaminants in the air, posing significant health risks to residents and first responders. The study identifies inhalation exposure routes through volatile and semi-volatile organic pollutants, highlighting the need for better preparation and safety protocols.
A pre-emptive skin regimen can significantly reduce skin-associated toxicities associated with panitumumab for metastatic colorectal cancer treatment. The study found that this approach reduced the incidence of grade 2 or higher skin toxicities by over 50%. Patients who received prophylactic treatment reported improved quality of life,...
Researchers at UT School of Public Health found a strong link between PVL and severe CA MRSA infections. Using animal models, they identified PVL as a potential vaccine target against these deadly strains.
Researchers found that photodynamic therapy, combining a topical photosensitizer and laser treatment, increases collagen levels and produces other skin changes in sun-damaged skin. The treatment may be particularly effective for skin with severe sun damage.
A study found that oral vitamin D supplements increased cathelicidin production in the skin of patients with atopic dermatitis, a common form of eczema. This increase helped to correct a defect in the immune system and reduce the risk of skin infections.
Researchers have found that nanoparticles can pass through human skin, especially when damaged, raising concerns about their safety. The study, led by Dr. Lisa DeLouise, used mice as a model and showed that nanoparticles accumulate in skin folds and around hair follicles.
Researchers at the University of Nebraska-Lincoln found that people who react strongly to threatening visual images and sounds tend to support public policies protecting society over individual privacy. This study controlled for factors like gender, age, and income, suggesting a link between biology and political opinions.
Topical estradiol application stimulates collagen production in sun-protected skin of older men and women, but not in sun-exposed areas like the face or arms. This study found that natural aging and photo-aging share biochemical features, including a reduction in collagen, which is essential for maintaining skin's inner layer structure.
A genetic mutation in the filaggrin gene increases the risk of developing atopic dermatitis by threefold, while also predisposing individuals to hay fever and asthma. The study found that nearly 8% of German school children carry this genetic variation.
Researchers found that UVA1 phototherapy is effective for patients with morphea and related diseases regardless of skin type. The study analyzed over 100 patients and showed no significant correlation between skin type and clinical improvement scores.
Researchers found that a natural lipid, phosphatidylserine, can prevent collagen reduction and increase MMPs in both natural and UV-induced aging. Topical application of the molecule may be a simple way to slow down skin wrinkling.
Researchers at the University of Minnesota have developed a new standard of care for children with recessive dystrophic epidermolysis bullosa (RDEB) using cord blood and bone marrow transplants. The treatment has shown promising results in improving skin quality and reducing blisters, offering new hope for these patients.
Researchers discovered a molecular alarm system in the skin that detects defects and triggers an immune response, leading to potentially harmful effects. The study found that genetic abnormalities in the skin can lead to an overproduction of white blood cells, which can be life-threatening.
Researchers found a common core skin microbiome in healthy individuals, dominated by Proteobacteria species. The study establishes the basis for determining a core microbiome, which may hold the key to novel treatments for skin conditions like acne and atopic dermatitis.