Articles tagged with Skin
Researchers at the University of Cincinnati have shown that pulsed-dye laser treatment improves burn scar appearance, texture, and elasticity. The study found significant improvements in redness, scar thickness, and biomechanical properties, with potential implications for further refining treatment options.
Researchers found that blocking adenosine receptors can reduce scar size and improve skin quality, offering new hope for victims of burns, wounds, or illnesses. The discovery could lead to new agents diminishing scarring and disfigurement.
Scientists have engineered a peptide inhibitor to target specific skin proteases, offering potential relief for people with conditions such as eczema and dermatitis. By modifying the binding surface of sunflower trypsin inhibitor, researchers created novel inhibitors that may help restore the skin's original state.
Researchers have found a key molecule, REG3A, highly expressed in skin cells during psoriasis and wound repair, causing abnormal cell proliferation. Blocking REG3A delays wound healing and clears up psoriasis-like pathology in mice, offering potential therapeutic targets.
A population-based study from the UK suggests that psoriasis is associated with an increased risk of developing type 2 diabetes. The study found that patients with severe psoriasis were more likely to receive prescription diabetic therapy and had a trend towards being prescribed insulin.
A University of Manchester study found Johnson's Baby Extra Sensitive Wipes equivalent to water in hydrating newborn skin, challenging current NICE guidelines. The trial involved 280 babies and showed no significant differences in hydration or secondary outcomes, except for a slight increase in napkin dermatitis.
Researchers at the University of Pittsburgh School of Medicine have identified an agent called E4 that can protect the skin and lungs from fibrosis, a process that can lead to organ failure and death. The agent may work by stalling the cross-linking of collagen needed to form thick scars.
Researchers discovered a causal link between chronic skin inflammation and cardiovascular disease, with aggressive reversal of psoriasis reducing the risk. A mouse model demonstrated that persistent inflammation leads to vessel wall inflammation and blood clot formation, which can increase stroke or heart attack risk.
A team of researchers, led by Professor Todd Coleman, has been awarded a Grand Challenges Explorations grant to develop flexible tattoo-like devices for continuous pregnancy monitoring. The devices, which use skin-mounted electronics systems, aim to detect signs and symptoms of pre-term labor in a reliable and non-invasive manner.
Researchers at Karolinska Institutet have made a significant breakthrough in understanding the stratum corneum, the outermost layer of human skin. By determining its molecular structure and function at a detailed level, they aim to develop new methods for drug delivery via the skin.
A recent study published in Sports Medicine found that skin problems are a common complaint among Summer Games athletes. Early correct diagnosis is crucial for athletes to participate and compete at their full potential.
A team of scientists proposes that early four-legged creatures used dermal bones to neutralize acid buildup from breathing carbon dioxide on land. The bones, featuring complex ridges and furrows, may have helped these ancient animals buy more time on land by storing antacids.
Researchers found thyme to be the most effective herbal preparation against Propionibacterium acnes, the bacteria causing acne. Thyme tincture surpassed standard benzoyl peroxide concentrations in antibacterial action, offering a gentler alternative for skin sensitivity sufferers.
Scientists have developed thin, flexible 'electronic skin' patches that can monitor brain, heart, and muscle activity without wires or invasive procedures. The patches can be applied to the skin like temporary tattoos and provide real-time health data through wireless capabilities.
Scientists have created a new buoyant material inspired by the water strider's ability to walk on water. The material, made from nanocellulose aerogel, can absorb huge amounts of oil and float on its surface, making it potentially useful for cleaning up oil spills.
Ingenol mebutate, a new topical gel, is applied for just a few days and shows comparable results to current therapies. The treatment significantly reduces the time needed to treat actinic keratosis, a common precursor to sun-related squamous-cell carcinoma.
A study published in the British Journal of Dermatology found that itching sensations vary by body site, with the ankles and backs exhibiting greater intensity and longer-lasting relief through scratching. Researchers suggest specific nerve fibers may be involved in pleasure-related sensations.
The CDC completed a comprehensive study of Morgellons, finding no infectious agent and no environmental link. The researchers enrolled 109 persons with symptoms, ruling out infection through extensive testing, and determined the fibers were fragments of cloth or debris.
New research reveals a surprising connection between autoimmune diseases and wounds that don't heal, with patients experiencing protracted recovery times. The study found that 23% of patients with open wounds had underlying autoimmune diseases, including rheumatoid arthritis and lupus.
Research identifies autoimmune diseases as a possible underlying cause of non-healing wounds. Patients with these conditions often experience significantly larger and more difficult-to-treat wounds that require skin grafts or amputations.
A new surgical care bundle of 12 measures, including smoking cessation and gown change prior to skin closure, reduced Whipple procedure wound infections by 49% compared to a less comprehensive routine preoperative preparation. The measures also included intraoperative wound edge protection and chlorhexidine-alcohol skin preparation.
A new study published in The Lancet suggests that a 2cm excision margin for skin melanomas thicker than 2mm is safe and effective, with similar levels of recurrence and death compared to a larger 4cm margin. This finding challenges current recommendations and may lead to changes in treatment guidelines.
A soy germ-based supplement containing Natural S-equol significantly improved the appearance of crow's feet skin wrinkles in Japanese menopausal women, suggesting potential to slow skin aging. The study found that doses of 10 or 30 milligrams of Natural S-equol daily had beneficial effects on crow's feet wrinkles.
A study of seven patients found that wearing a custom-designed pressure device on the ear at night supplemented surgical excision and steroid injection to effectively treat auricular keloids. The device showed safety and efficacy, with no itch, pain or abnormal sensations reported by treated patients.
Researchers created a device platform that combines electronic components for sensing, medical diagnostics, communications, and human-machine interfaces on an ultrathin skin-like patch. The circuit bends and stretches like the skin, allowing for comfortable wear and freedom of movement.
A systematic review of 32 trials involving 3128 patients found that cocaine-free topical anaesthetics substantially reduce pain without triggering serious side effects. These agents offer an attractive alternative to injecting pain killers into damaged tissue, making them easier and less painful for patients.
A recent genetic study found a link between a specific gene variant and lower body fat percentage, yet an increased risk of type 2 diabetes and heart disease. The researchers discovered that this gene only affects the subcutaneous fat under the skin, which may store fat elsewhere in the body, increasing organ function interference.
Physicians have identified six new cases of purpura, a debilitating skin condition caused by cocaine contaminated with the de-worming drug levamisole. Treatment involves stopping cocaine use and administering steroids to prevent inflammation.
Balicatib, a new osteoporosis treatment, causes skin hardening syndromes in patients. Researchers at Boston University School of Medicine found that the drug inhibits CathepsinK, leading to collagen and elastin degradation.
A study found that biopsies and patient-provided specimens revealed dermatitis, excoriation, and ulceration but not objective evidence of skin infestation in patients with delusional infestation. Skin inflammation may trigger delusional symptoms in susceptible individuals.
Among patients referred by non-dermatologists, only one-fifth had a malignant primary lesion, while nearly half of all skin cancers discovered were not the referral lesion. Dermatologists found additional incidental malignant lesions, highlighting the importance of focused education on skin cancer detection.
Researchers found that skin contact with food allergens can lead to the reprogramming of gut-homing T cells into skin-homing T cells, exacerbating atopic dermatitis. This discovery has important implications for preventing and treating atopic dermatitis in patients with food allergies.
A study found that vitamin D deficiency is associated with higher fat levels in both black and white children, but racial differences exist in fat tissue distribution. Vitamin D was also linked to lower levels of good cholesterol in all subjects.
A study of 92 children with eczema found that routine use of topical corticosteroids does not lead to skin thinning. The researchers used dermoscopy to examine the treated and untreated skin of the children, concluding that TCS use is safe and effective for managing childhood eczema.
Researchers have identified specific bone marrow cells that can transform into skin cells to repair damaged tissue. The discovery provides new insights into the mechanisms behind skin repair and has the potential to revolutionize approaches to wound treatment.
Scientists at Brigham and Women's Hospital have developed nanoparticles containing calcium that can capture nickel efficiently without penetrating the skin. This breakthrough could provide a new strategy for preventing nickel-induced contact dermatitis, affecting millions worldwide.
A study by Indiana University School of Medicine found that tanning bed radiation can cause severe skin reactions, including toxic epidermal necrolysis, a life-threatening condition. The researchers advise caution when using tanning beds to treat undiagnosed skin conditions.
A new Johns Hopkins Children's study suggests that timely and proper wound cleaning and draining may be more important than the choice of antibiotic in treating MRSA skin infections. The researchers found that 95% of children recovered completely within a week, regardless of which antibiotic they received.
Scientists have discovered that lavender oil has a potent antifungal effect against strains of fungi responsible for common skin and nail infections. The essential oil was found to be lethal to dermatophytes and various species of Candida, making it a promising alternative to existing treatments.
Researchers at Ohio State University successfully treated two patients with cutaneous leishmaniasis, a parasitic skin infection common in tropical regions, using heat therapy. The long-term effectiveness of this treatment, especially in people with compromised immune systems, makes it an appealing alternative to traditional drug therapy.
Physicians report time constraints and patient embarrassment as significant barriers to conducting full-body skin examinations. Dermatologists are more likely than internists and family practitioners to perform these screenings.
Recent research suggests that P. acnes within the body may be the cause of infections, contradicting previous assumptions about contamination from skin. This oversight could lead to incorrect diagnoses and complications if treated with the wrong bug.
A new study published in the Journal of Allergy and Clinical Immunology found that both the stratum corneum and tight junctions play a crucial role in eczema development. Tightening both leaky barriers may be an effective treatment approach, targeting the faulty tight junction protein claudin-1.
Researchers have identified bacterial products that enable Staphylococcus epidermidis biofilms to detach from surfaces, leading to infection. Inhibiting these mechanisms could provide a new approach to preventing biofilm-associated infections.
A new study suggests that black rice bran extract can reduce skin inflammation by 32% compared to control animals. Feeding mice a diet with black rice bran also showed a significant reduction in swelling associated with allergic contact dermatitis.
Researchers at the University of Gothenburg have made a groundbreaking discovery about contact allergy, which affects nearly 20% of Europe's population. The study found that fragrances can cause allergic reactions when exposed to oxygen in the air, leading to eczema in some individuals.
Researchers at the University of Gothenburg have discovered how sunscreens break down in sunlight, leading to an increase in contact allergy. The study has led to the development of a new test for photocontact allergy, which could help patients avoid substances that cause allergic reactions.
A study found that one in ten US adolescents uses sunless tanning products, which may reduce sunbathing and sunburns among adult women. Another study showed that promoting sunless tanning as an alternative to regular tanning can lead to reduced UV radiation exposure and improved sun safety behaviors.
Researchers found a genetic rarity where disease-causing genes can self-repair, resulting in spots of normal skin amidst diseased skin. The recombination of chromosomes prior to cell division leads to cells with either two mutant copies or no mutant copies, forming normal skin patches.
Researchers at North Carolina State University developed tiny microneedles that can deliver quantum dots, nanoscale crystals, into the skin for diagnosing and treating various medical conditions. The technology uses multiphoton microscopy to visualize quantum dot delivery, paving the way for more rapid cancer diagnosis and treatment.
Researchers found that some body areas are more resistant to tanning than others, with the buttock being particularly resistant. People with no freckles also tanned more easily than those with freckling.
Researchers will investigate why atopic dermatitis patients are susceptible to staph and other bacterial and viral infections, and evaluate the effectiveness of vitamin D in reducing or preventing staph colonization. The study aims to contain drug-resistant MRSA infections and widespread viral skin infections.
Researchers found desert-living bats have reduced cutaneous water loss compared to non-desert species, with a potential mechanism involving lipid composition adjustments. This adaptation could provide significant insight into how bats cope with future climate changes.
Scientists developed a fast, simple and inexpensive test for detecting chemicals that cause contact dermatitis, eliminating the need for animal testing. The test uses nitrobenzenethiol as a skin protein surrogate, producing positive results for known skin irritants and negative results for non-irritating substances.
A University of Illinois study found that a specific omega-6 fatty acid is critical for maintaining healthy skin. Without this acid, mice developed severe ulcerative dermatitis, which was reversed when the acid was added to their diet.
Researchers from P&G Beauty & Grooming present studies on skin care science, including the impact of hexamidine on stratum corneum lipid metabolism pathways and its potential to restore aging skin's barrier function. Eleven posters will be displayed at the AAD Annual Meeting showcasing diverse research topics.
Researchers have identified five cases of toilet-seat dermatitis, a skin condition that can be caused by wooden toilet seats or exposure to harsh cleaning chemicals. The study recommends using paper toilet seat covers, replacing wooden seats with plastic ones, and avoiding harsh cleaners to prevent the condition.
Researchers at Albert Einstein College of Medicine developed a new approach to treat and heal skin abscesses caused by antibiotic-resistant staph bacteria using nitric oxide-releasing nanoparticles. The therapy was shown to clear up infections and promote healing in mice, offering a potential breakthrough in treating MRSA infections.
Researchers used high-frequency ultrasound with elastography to identify skin cancer with high accuracy, distinguishing between malignant and benign lesions by measuring their elasticity. This non-invasive procedure can aid physicians in treatment and reduce the number of unnecessary biopsies of benign skin lesions.
A three-year study in remote communities found a significant reduction in skin sores among Aboriginal children, with over 6000 assessments conducted on nearly 2500 children. The program's success highlights the importance of local education and treatment, but ongoing efforts are needed to address underlying causes such as poor housing ...