Articles tagged with Skin
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Researchers have developed a novel topical therapy targeting genetic abnormalities in deeper skin layers to improve psoriasis symptoms. The new treatment, Dual-F-NALP, has shown promising results by reducing inflammation and suppressing immune hypersensitivity.
Researchers have identified two genetic variations associated with persistent atopic dermatitis in African-American children, shedding light on the skin disorder's mechanisms. The study found that loss-of-function mutations to Filaggrin-2 were linked to increased risk of AD in African American children.
Primary care physicians who took an online training course about skin cancer detection significantly improved their skill to properly diagnose and manage benign and malignant lesions. The enhanced skill level led to a reduction in unnecessary referrals to dermatology specialists.
A study found that lawsuits related to procedures when non-physicians operate the laser are increasing, particularly outside traditional medical settings. Non-physician operators, including nurse practitioners and medical assistants, were involved in 75.5% of hair removal lawsuits from 2004 to 2012.
A new University of Michigan study found that Medicare's data source for reporting rates of pressure ulcers is not accurate for comparing hospital quality. The study revealed drastic differences in performance depending on the type of data used.
Researchers have identified a potential new therapy for eczema by blocking sensory nerves' itch receptors, which may prevent severe consequences like asthma and allergies. The treatment targets the immune system's role in reacting to chemicals that cause itching and inflammation.
A recent study published in the Proceedings of the National Academy of Sciences has discovered that two sets of nerve receptors in the skin convey information about fine textures through vibrations. This finding suggests that humans can discriminate between different fine textures, such as silk and satin, through these subtle vibrations.
A study published in JAMA Dermatology found over 200 mobile apps related to dermatology, but most are free with no guarantees of accuracy. Doctors advise users to use common sense and cross-reference apps with other sources before relying on them.
Researchers at Bonn University have discovered that UV-light induced DNA damage triggers lupus-like autoimmune symptoms by activating the cGAS signaling pathway. This study provides a crucial understanding of the immune mechanism behind lupus and offers potential new therapy targets.
A study by UNC researchers found that over three-quarters of Hispanic patients in North Carolina aren't performing skin self-exams, highlighting the need for better education and physician guidance on this potentially life-saving practice.
A structural defect in skin cells, specifically desmoglein 1, contributes to allergy development, including skin and food allergies. This finding could lead to a better understanding of the importance of other structural proteins in the skin barrier.
Researchers from Penn Medicine discovered that the immune system governs the skin microbiome, which is crucial for maintaining diverse microbes and healthy skin. The complement system, an ancient branch of the immune response, influences the skin microbiome.
Researchers have developed a new subcutaneous implantable cardiac defibrillator (S-ICD) that detects abnormal heart rhythms and delivers shocks without wires touching the heart. The device has shown promising results in a 33-site study, with 99% of patients remaining complication-free 180 days after implantation.
A genetic study conducted by 23andMe has identified four genetic markers associated with the development of non-syndromic striae distensae (stretch marks), a skin condition affecting approximately 50-80% of people. The study suggests that elastin, a key component of elastic fibers in the skin, plays a crucial role in the formation of s...
A psoriasis researcher has received a third NIH grant to explore the nervous system's involvement in psoriasis. The study aims to identify new targets for drug development and improve patient care by investigating nerve-derived peptides critical to sustaining the disease.
A Marshall University researcher has developed a technology for repairing skin injuries using nanotechnology. The $20,000 grant will help produce device prototypes and market the product to potential customers.
A small study at Massachusetts General Hospital found evidence of nerve damage in approximately half of fibromyalgia patients, leading to the identification of a treatable disease called small-fiber polyneuropathy (SFPN). Researchers hope that this discovery will lead to better treatments for some with chronic pain syndrome.
A new study reveals that pressure ulcers in children are more common than previously thought, with medical devices such as facemasks and pulse oximeters identified as major contributors. Cincinnati Children's researchers developed a quality improvement initiative that reduced pressure ulcers by 50 percent.
A recent study suggests that eczema can trigger food sensitivity in babies, potentially leading to the development of food allergies. Infants with impaired skin barriers and eczema are over six times more likely to be sensitized to common allergenic foods like egg, cow's milk, and peanut.
A team at Jadavpur University has developed a computer algorithm that can analyze the minutiae of blood vessels revealed by an infra-red scan of a person's face. The thermogram shows the pattern of blood vessels almost down to the smallest capillary with an accuracy of over 97%, making it suitable for high-security applications.
The National Psoriasis Foundation has awarded twelve fellowships totaling nearly half a million dollars to researchers working to cure psoriasis and psoriatic arthritis. The fellowships will support studies on the impact of diet, exercise, and lifestyle on psoriasis severity and treatment outcomes.
Research found that crocodylians have unique multi-sensory organs called dome pressure receptors or Integumentary Sensory organs, which grant fingertip sensitivity and detect surface pressure waves. These sensors also help regulate body temperature and detect suitable habitats.
A breakthrough discovery by scientists at Integrated Tissue Dynamics LLC has provided a biological rationale for fibromyalgia. Researchers found an increase in sensory nerve fibers around specialized blood vessel structures in the skin of female patients with fibromyalgia, which may be driving the reported symptoms.
Researchers discovered that immune system cells and lymph capillaries regulate sodium balance and blood pressure in the skin, contrary to traditional views focusing on the kidney and brain.
New UK coins made of nickel-plated steel will increase exposure to nickel, potentially causing a four-fold rise in skin allergies. Scientists analyzed the new coins and found that handling them for one hour can deposit four times more nickel onto the skin than copper-nickel coins.
Researchers sequenced DNA of fungi at skin sites to define normal populations and provide framework for investigating fungal skin conditions. The study found that feet, including toenails, heels, and toe webs, contain tremendous diversity of fungi.
A novel gene associated with canine atopic dermatitis has been identified by researchers. The gene encodes a protein called plakophilin 2, which is crucial for the formation and proper functioning of the skin structure. This finding opens new possibilities in understanding the disease mechanism leading to atopic dermatitis.
Researchers found that exposure to sunlight lowers blood pressure and improves overall health by reducing the risk of heart attack and stroke. The study's results suggest that the benefits of sunlight outweigh the risks of skin cancer.
Researchers at Boston University School of Medicine found that UVA induces progerin protein, accelerating skin aging, linked to genetic and environmental factors. Long-term exposure to UVA rays, particularly from tanning beds, accelerates photoaging by causing alternative splicing of the LaminA gene pre-mRNA.
Scientists developed a cell-based alternative test that uses mouse skin cells in the laboratory to detect skin sensitisers. The test was found to be highly accurate, correctly identifying actual sensitizers in 92% of cases and producing no false positives.
A new syndrome, juvenile-onset small-fiber polyneuropathy (JOSeFINE), has been identified as a possible cause of widespread chronic pain in children. Diagnostic tests including skin biopsies and autonomic function testing have been found to be useful in diagnosing the condition.
Researchers discovered two strains of acne bacteria associated with pimples and one strain linked to healthy skin. Increasing the body's friendly strain through a cream or lotion may help calm spotty complexions.
A recent study by UCLA and Washington University researchers discovered that acne-causing bacteria contain both 'bad' and 'good' strains. The 'good' strain is found in healthy skin but rarely occurs in those with acne, suggesting it may have a natural defense mechanism to protect the skin.
Researchers from University of Southern Denmark used RICS technique to investigate liposome movement on skin. They found that liposomes are destroyed before entering the skin and spilling their cargo of active ingredients. The study advises against trusting claims about liposomes carrying active ingredients into the skin.
Newborns require gentle and careful skin care to prevent infection and irritation. The Mayo Clinic suggests bathing every other day, using warm water only a few inches deep, and selecting mild cleansers without dyes or fragrances.
Researchers develop small peptide that blocks antibody recognition of desmogleins, improving cell-cell adhesion and preventing skin blistering in mice. The peptide could serve as a potential treatment option for pemphigus vulgaris, a life-threatening autoimmune skin disease.
Researchers found a small peptide that blocks antibody recognition of desmogleins, improving cell-cell adhesion and preventing skin blistering in pemphigus vulgaris. Additionally, spironolactone reduced vascular calcification in kidney disease mice, increasing their life span. A glioblastoma fusion gene promoted tumor growth and progre...
Eczema is a persistent skin rash that can be triggered by inadequate Ctip2 protein, leading to inflammation and immune dysfunction. Researchers have identified two ways in which improper Ctip2 function contributes to eczema, paving the way for personalized treatments and new therapies.
Researchers have identified previously unseen anatomy preserved in fossils using synchrotron-based imaging techniques. The study reveals that a 50 million-year-old lizard skin contains teeth, changing the understanding of this fossil animal.
Researchers at the University of Michigan have made skin cells in senior citizens act like younger cells again by adding more filler to the surrounding extracellular matrix. The study shows that this approach can trigger a signal for cells to wake up and respond positively to alterations in their environment.
Researchers found that metal-binding agents applied to the skin, prescribed for autism treatment, are not absorbed and ineffective. The study contradicts claims made by some practitioners treating children with mercury-binding agents.
Angioedema, a rare but serious condition, can be misdiagnosed or under-treated due to lack of understanding. The report aims to provide best clinical practices for diagnosing and managing all its forms, helping patients find relief and live healthy lifestyles.
A study published in the Journal of Clinical Investigation found that mice lacking interleukin-36 (IL-36) were protected from psoriasis-like skin inflammation. This suggests that targeting IL-36 could be a promising approach for treating psoriasis.
Researchers found that mice exposed to a drug that increases TSLP levels are protected from developing skin tumors. Elevated TSLP also triggers an immune response that targets and destroys cancer cells. The study suggests that hyper-vigilance of the immune system may have benefits in fighting off skin cancer.
New study finds that blocking leukotriene B4 production reduces allergic skin inflammation in mice with eczema. Neutrophil recruitment to the skin is essential for the disease's development.
A new study suggests that elephant skin hair plays a role in heat dissipation, allowing them to maintain a constant body temperature in hot regions. Researchers found that sparse skin hair increases heat loss from the skin, benefiting large terrestrial mammals like elephants.
A new University of Nottingham study will examine the incidence and impact of gluten intolerance in the UK, focusing on coeliac disease and dermatitis herpetiformis. The research aims to improve diagnosis rates and healthcare for affected individuals, with a goal of creating a more accurate estimate of the condition's prevalence.
Researchers find harmless virus living on skin that naturally targets and kills Propionibacterium acnes bacteria, a major trigger of acne. The discovery offers promising new hope for developing targeted anti-acne therapies.
Researchers developed an advanced optics system to noninvasively map out the network of tiny blood vessels beneath the outer layer of patients' skin, potentially revealing telltale signs of disease. The imaging system shows promise for clinical application in diagnosing and treating skin cancer.
Case Western Reserve University researcher Nicole Ward is leading a study to identify the mechanistic link between psoriasis and heart attack/stroke. The study aims to provide first-ever evidence that cell-specific events in psoriasis can be targeted for treatment, potentially improving cardiovascular disease outcomes.
A new laser-based system can propel tiny, precise streams of medicine into the skin with minimal force, potentially eliminating pain from injections. The device uses an erbium-doped yttrium aluminum garnet laser to create a vapor bubble that forces drug-laden jets into the targeted depth of the skin.
A recent study in Rochester, NY, documents 19 cases of infected tattoos caused by a type of bacteria often found in tap water. Premixed gray ink is the suspected source of the infection, which was treated with antibiotics and resolved in most patients.
Researchers have identified Demodex mites as the primary carriers of bacteria that trigger rosacea. The bacteria produce molecules provoking an immune reaction in patients, leading to tissue degradation and inflammation.
Researchers have developed a groundbreaking treatment for venous leg ulcers, which showed significant improvements in wound closure and healing time. The study found that patients who received the treatment experienced faster healing and a higher likelihood of wound closure compared to those in the control group.
Researchers at the National Institutes of Health discovered that beneficial bacteria in the skin play a crucial role in protecting the body from infection. The study found that commensal bacteria work with immune cells to fight off harmful microbes, providing new insights into the importance of skin health and microbiota.
Researchers at the University of Cincinnati have shown that pulsed-dye laser treatment improves burn scar appearance, texture, and elasticity. The study found significant improvements in redness, scar thickness, and biomechanical properties, with potential implications for further refining treatment options.
Researchers found that blocking adenosine receptors can reduce scar size and improve skin quality, offering new hope for victims of burns, wounds, or illnesses. The discovery could lead to new agents diminishing scarring and disfigurement.
Scientists have engineered a peptide inhibitor to target specific skin proteases, offering potential relief for people with conditions such as eczema and dermatitis. By modifying the binding surface of sunflower trypsin inhibitor, researchers created novel inhibitors that may help restore the skin's original state.
Researchers have found a key molecule, REG3A, highly expressed in skin cells during psoriasis and wound repair, causing abnormal cell proliferation. Blocking REG3A delays wound healing and clears up psoriasis-like pathology in mice, offering potential therapeutic targets.
A population-based study from the UK suggests that psoriasis is associated with an increased risk of developing type 2 diabetes. The study found that patients with severe psoriasis were more likely to receive prescription diabetic therapy and had a trend towards being prescribed insulin.