Articles tagged with Skin
Researchers found that a protein called STAT3 is crucial for the development of psoriasis and can be reversed with a specific treatment. The study's findings offer a potential new target for medications to relieve symptoms of psoriasis.
Researchers at the University of Michigan have discovered a compound that suppresses cell growth in psoriasis models, offering new hope for treating this life-long genetic condition. The compound, benzodiazepine-423, is selectively applied topically and shows great potential for controlling disease progression.
Researchers found that laser resurfacing can improve the look of sun-damaged skin and reduce acne scars with nonablative laser treatment. Increasing volume of botulinum exotoxin A at lower concentrations affects a larger area, making it suitable for treating larger areas like the forehead.
Brett Wong's research identifies histamine receptors as contributing to increased blood flow during heat stress, which can help improve survival rates among elderly and those with conditions like diabetes and heart disease.
Burn victims may soon experience restored faces with a single operation, reducing pain and recovery time. Surgeons utilize innovative techniques to create thick skin flaps with unique blood supplies, eliminating huge scars and promoting emotional healing.
Barbed sutures enable minimally invasive facial rejuvenation with limited downtime, while ultrasonic body contouring provides liposuction-like results without pain or recovery time. Wrinkle fillers like Restylane and Sculptra are expected to skyrocket in demand due to their effectiveness.
Researchers found that muscle mechanoreceptor stimulation, independent of central command, significantly increased forearm sweat rate during passive cycling recovery. In contrast, chest sweat rate was only increased at the mid-recovery period. The study suggests that muscle mechanoreceptors are equally important in producing sweat as h...
A new product developed for soft tissue augmentation showed high efficacy and patient satisfaction rates of 74%, 80%, and 88% respectively. Moderate pain occurred in 59% of patients, but resolved within two weeks. Long-term safety profile remains unknown.
Researchers at Saint Louis University are testing a new, attenuated vaccine against smallpox, which could be administered to individuals with compromised immune systems. The study aims to explore the safety and efficacy of this investigational drug in a broader population.
Musicians may experience skin problems due to prolonged contact with instruments, particularly those using rosin, nickel, or other materials. Changing instrument components or adjusting playing positions can help alleviate these conditions.
Researchers at Massachusetts General Hospital found that nerve damage in one area can cause a loss of skin nerve endings on the opposite side, suggesting a previously unknown communication between nerve cells. The study used rats and demonstrated precise communication between matching nerves.
A new study found that even a small amount of psoriasis can significantly affect daily life, impacting over 4.5 million Americans with the disease. Psoriasis patients often feel like their condition is a burden and are dissatisfied with treatment options.
Researchers found that a peptide called LL-37 selectively kills the vaccinia virus in the smallpox vaccine, which could enable thousands of civilians or military personnel with atopic dermatitis to receive the vaccine. This breakthrough may lead to safer testing and better predict and control reactions to the vaccine.
Researchers found that digital photographs improved detection of new or changed moles, increasing accuracy by over 10% compared to skin self-examinations alone. Baseline photography may effectively improve diagnostic accuracy in patients performing skin self-examinations.
Researchers at the Medical College of Georgia found that glycerin helps skin cells mature properly, which can aid in treating diseases like psoriasis and non-melanoma skin cancers. Glycerol was shown to produce a signal that directs normal skin cell maturation, and its absence may lead to hyper-proliferative, thick skin.
Researchers developed a novel fluorosugar modifier that prevents leukocyte migration to inflamed skin. This finding offers new hope for treating inflammatory diseases.
Researchers have identified over 2,700 genes with unusual activity in people with scleroderma, a mysterious skin disease. The study's findings suggest the disease is systemic, not confined to visible skin patches, and may lead to improved diagnosis and targeted treatment options.
Researchers review new glucose monitoring technologies, including non-invasive options that could lead to better compliance with testing recommendations. Continuous glucose monitoring systems also hold promise for early detection of hidden glucose trends.
A new study by Cincinnati Children's Hospital Medical Center shows that leaving vernix on newborn skin can improve hydration, reduce scaly texture, and promote a faster decrease in pH. The researchers hope to develop a synthetic equivalent for use in various applications, including wound dressings and medication delivery systems.
A recent study found that people with atopic dermatitis or eczema, and their household contacts, are at increased risk of complications from smallpox vaccination. The study suggests that the screening process may not be effective in identifying individuals who should not receive the vaccine.
A study published by the American Physiological Society reveals a strong correlation between plantar pressure and skin perfusion distribution in diabetic patients. The researchers found that areas with high plantar pressures, such as the metatarsal heads, had significantly lower skin perfusion values.
Researchers found that mice with a mutation in the fatty acid transport protein 4 (FATP4) gene lack wrinkles and normal hair growth. The study suggests that FATP4 plays a critical role in skin development, potentially leading to new treatments for obesity and other conditions.
Researchers at McGill University have discovered a molecule that accelerates wound healing, providing a potential treatment option for millions of Americans suffering from burns and chronic skin ulcers. The growth factor progranulin has been shown to improve skin repair, offering new hope for individuals affected by these conditions.
Researchers found that eczema patients have impaired immune response, preventing adequate antimicrobial peptide production in their skin. This deficiency may lead to increased susceptibility to skin infections, such as staphylococcus aureus and herpes simplex.
A new study investigates blood flow in toads' pelvic skin while absorbing water, finding a significant increase in red cell velocity prior to water exposure and a seven-fold increase within one minute. The results support the initial hypothesis that increased blood flow is associated with water absorption behavior.
A new study found that DEET-based insect repellents were significantly more effective than plant-based alternatives in preventing mosquito bites. The study tested 16 representative products and found that DEET-based products provided the longest-lasting protection, with some lasting up to five hours.
A new study found that the continuous stitching technique significantly reduced pain in women with perineal damage after childbirth. The method also resulted in fewer suture removals within three months compared to interrupted suturing. This could lead to cost savings and improved outcomes for patients.
Self-tanners contain dihydroxyacetone (DHA), which interacts with skin proteins to create a brown glow. Newer sunscreens offer greater protection against both UVA and UVB radiation, including those developed by Craig Bonda, who found that adding DEHN to avobenzone extends its effectiveness.
Researchers will study cellular changes, immune responses, and collagen production to develop more effective treatments for scleroderma. The NIH grants will complement existing investments in scleroderma research and bring scientists closer to finding treatments for this disease.
Researchers measured the force required to overcome tissue-needle connection during acupuncture needling, finding a significant pullout force when needles were rotated. The study suggests that layers superficial to muscle may be involved in the body's response to acupuncture, with future research focusing on connective tissue's role.
The skin's acid coating, composed of fatty acids, helps maintain strength and cohesiveness. The discovery could aid in developing therapies for skin problems like psoriasis.
Researchers have identified a sequence of amino acids found in fibronectin that accelerates healing of hard-to-treat skin wounds in obese, diabetic mice. The substance completely healed skin puncture wounds in eight days, compared to 20-42 days in untreated diabetic mice.
Steven J. Swoap, an assistant professor of biology at Williams College, has been awarded a $497,000 National Science Foundation (NSF) grant to investigate the mechanism of how restricting caloric intake lowers blood pressure. He will also receive a $95,783 NIH award to study why skeletal muscle becomes more fatiguable under disuse.
Scientists at the University of Chicago Medical Center have discovered a key gene that enables skin to acquire its barrier function, which is crucial for preventing dehydration and infections in premature babies. The study uses genetically engineered mice with a mutated Klf4 gene to demonstrate the importance of this factor.
Researchers discovered that UV radiation blocks the ability of skin cells to recognize retinoic acid, a nutrient made from vitamin A. This triggers a cascade of biochemical changes, causing a functional vitamin A deficiency in human skin. Pretreating skin with retinoic acid before UV exposure can limit the damage.
Two studies presented at the American Academy of Dermatology meeting suggest that primary care doctors often refer patients with skin problems to dermatologists, wasting time and resources. Dermatologists diagnose skin diseases more quickly than other doctors, saving money for both patients and healthcare systems.
Teenagers who use substances to manage stress may be more likely to develop impulsivity disorders. Those who don't exhibit this coping mechanism are less prone to substance abuse and addiction.
Neuroscientists at Johns Hopkins discover that nerve signals can originate from nerves not directly injured, leading to abnormal activity in nearby nerves. The study provides a basis for targeting the skin and suggests effective therapy options for neuropathic pain syndromes.
Researchers discovered that Endermologie, a non-invasive treatment, creates collagen bands parallel to the skin surface, leading to smoothing of cellulite. The study found no evidence of fat metabolism or new blood vessel formation.
Researchers have found that tacrolimus can effectively treat moderate-to-severe atopic dermatitis in children, with a success rate of 67-70% and minimal systemic side effects. This treatment approach offers an alternative to corticosteroid ointments, which can cause skin thinning and other complications.
A Wake Forest University School of Medicine study found that patients with skin problems receive inadequate comprehensive care from primary care doctors, who focus solely on the skin issue. Dermatologists provide superior treatment due to their specialized expertise, and previous studies have shown they are cost-effective as well.
A team of researchers at Thomas Jefferson University has developed a transgenic mouse to study the causes and effects of photoaging on human skin. The mouse line enables scientists to learn more about how ultraviolet light rays cause skin aging and wrinkling, and how this can be prevented through better sunscreen formulations.
A recent Penn State study reveals that older adults have a decreased ability to cool their bodies and pump blood efficiently in extreme heat, increasing the risk of cardiovascular problems. Even healthy older individuals with heart disease should take precautions to stay cool and minimize strain on their hearts.