Articles tagged with Molecular Physiology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Quantitative disease resistance is a promising approach to combat plant diseases, which cause an estimated 13% loss of global crop yields annually. Researchers aim to identify disease resistance mechanisms for important corn diseases and develop genetic resources for the broader maize genetics community.
The German Research Foundation has granted funding to Johannes Gutenberg University Mainz (JGU) and its strategic alliance partners for four years. Researchers in materials sciences, biophysics, and medicine are working on three collaborative projects with a total funding volume of EUR 35 million. The focus is on developing multiscale ...
A study in a mouse model found that viral infections during pregnancy can affect the mother's brain and disrupt maternal care behavior after birth. The research team identified structural, molecular, and functional changes in the brains of mothers with viral-like immune activation.
Researchers found that repetitive exposure to environmental hypoxia prevented memory loss and reversed impairments in nerve-to-nerve communication. Adult offspring also inherited this protection against dementia.
The University of South Florida has received a five-year, $1.35 million NIH institutional grant to train scientists in vascular inflammation and injury research. The grant will support the comprehensive training of pre- and postdoctoral scientists focused on this emerging area of research.
Complimentary press passes are available for the EB 2022 meeting, featuring cutting-edge research and live scientific sessions. The event will also offer virtual access to press materials.
A Tel Aviv University study found a significant link between changes in G-protein-coupled receptors and brain adaptability. Disabling the voltage sensor of these proteins caused uncontrolled brain flexibility, leading to excessive habituation to odors.
Researchers discovered that living cell interiors become softer and more fluid during mitosis, a process crucial for life. The findings could help ensure precise separation of cellular structures into daughter cells.
Jochen Zimmer, a UVA professor, has been awarded $9 million by the HHMI to pursue his research on biopolymer transport across biological membranes. His work aims to develop new biomaterials for medicines, food, and energy, potentially combating diseases, hunger, and climate change.
Research by University of Arizona Health Sciences identifies chronic arsenic exposure as a risk factor for developing insulin resistance and glucose intolerance. The study found that prolonged activation of NRF2 protein leads to shifts in metabolic pathways, increasing glucose production in the liver.
A new preclinical study validates the spleen's role in cardiac healing and suggests targeting S1P as a potential treatment for heart failure. The study discovered interactions between S1P and the heart during transition from acute to chronic heart failure.
Scientists at Weill Cornell Medicine developed a computational technique that greatly increases the resolution of atomic force microscopy, revealing atomic-level details on proteins and biological structures. The new method allows researchers to study biological molecules under physiologically relevant conditions, providing high-resolu...
Researchers at HKUST create a novel optical tweezers-coupled Raman spectroscopy platform to analyze proteins in low concentrations, particularly IDPs. The study successfully characterizes the structural features of alpha-synuclein, an IDP linked to Parkinson's disease, at physiological concentration.
A clinical trial of alternate-day fasting found health benefits, including reduced inflammation and improved cholesterol levels. Participants experienced a mean calorie restriction of about 35% and lost an average of 3.5 kg during four weeks.
Researchers found that even low levels of traffic-related air pollution can cause inflammation and mitochondrial damage in the lungs of mice. The study's results suggest that people living alongside major traffic corridors should be aware of potential respiratory health risks.
Researchers at the University of Vermont have discovered that myosin-binding protein C (cMyBP-C) is essential for maintaining precise tuning in the heart's muscle cells. The protein plays a crucial role in controlling the interaction between myosin and actin, allowing for synchronized contraction and efficient pumping of blood.
The Scandinavian Plant Physiology Society (SPPS) has renewed its partnership with Wiley over sixty years ago. The journal Physiologia Plantarum, an international thought leader in plant physiology, benefits from the collaboration. With a global focus and members from various countries, SPPS promotes experimental plant biology research.
The University of Iowa team identified two key genes involved in moisture sensing, allowing fruit flies to detect subtle changes in humidity. This discovery provides crucial insights into the mechanisms of hygrosensation and its potential applications in understanding sensory processes.
A new study aims to identify markers for deadly blood clots in menopausal women by analyzing blood platelets. Researchers are testing their theory as part of the Kronos Early Estrogen Prevention Study, with hopes that it can lead to tools for doctors to provide hormonal therapy commensurate with a woman's risk.
Researchers discovered that a balance of low tidal volume and periodic deep inflation, or 'sighs,' is necessary to maintain open lungs while preventing ventilation-induced lung injury. The study found that overdoing 'sighs' can lead to further injury, highlighting the importance of finding an optimal frequency range for deep inflation.
A study found that 50% tomato juice drink completely prevented smoke-induced emphysema in mice, with lycopene cited as a key contributor. Researchers believe the model can be used to explore pathophysiology and therapeutic intervention for human diseases.
Researchers discover DMT1 protein shields lung cells from toxic particles, including vanadium, by regulating iron transport. The finding offers new insights into lung protection and potential therapeutic applications.
Resveratrol exhibited anti-inflammatory activity in all systems examined, including laboratory cell lines and human airway epithelial cells. The compound inhibited the release of inflammatory mediators, including IL-8 and GM-CSF, which play a major role in inflammation development.
Physiology aims to appeal to a broader audience with innovative features and artwork, showcasing the most up-to-date physiological research. The journal's design and editorial team are committed to making the content more accessible and readable.
The NIGMS initiative supports two Centers of Excellence in Chemical Methodologies and Library Development, focusing on high-throughput technologies to generate customized libraries. Researchers at Boston University and University of Pittsburgh will develop novel methods for synthesizing complex molecules and peptide mimetics.
Scientists at Max-Planck-Institute for Molecular Physiology develop a new concept for more efficient search of drug candidates. By employing biologically relevant natural products as starting point, the 'domain concept' aims to increase hit rate in compound libraries.
Armstrong's groundbreaking work elucidated the physical processes underlying electrical signaling in and between cells. His research has contributed significantly to our understanding of ion channels and their role in transmitting nerve impulses, with implications for drug development and treatment of various diseases.
The National Institute on Alcoholism and Alcohol Abuse has awarded a $7 million grant to Wake Forest University Baptist Medical Center to study the causes of alcohol addiction. The studies will provide insights into brain processes that lead to alcoholism, with a focus on understanding the fundamental actions of alcohol on the brain.