A five-year NIH-funded study will explore the role of glucagon hormone in human metabolism, focusing on its impact on insulin secretion, glucose regulation, and energy balance. The research aims to clarify glucagon's function and inform more effective drug development for obesity and Type 2 diabetes treatment.
The European Society of Endocrinology is launching a new campaign to raise awareness about the importance of hormone health. The #BecauseHormonesMatter initiative aims to improve public understanding of hormones and promote practical steps for better hormone health, following the success of last year's campaign.
Researchers at the University of Tsukuba identified a peptide hormone called Capa that regulates calcium levels in fruit flies. The study found that Capa is secreted by specific neurons and acts on organs similar to vertebrate kidneys to mobilize calcium from stored reserves.
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
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Researchers have discovered a synthetic peptide that attracts Crown-of-Thorns Starfish at low concentrations and with no toxicity, offering an efficient pest-management solution. This breakthrough may lead to the development of potent attractins to control CoTS outbreaks, protecting coral reefs from devastating damage.
Researchers have constructed a comprehensive map of synaptic connections between clock neurons in Drosophila, identifying novel neurons and connections that influence feeding, mating, and sleep behaviors. The study also reveals the role of light input pathways and neurotransmitters in regulating clock neuron function.
A new versatile platform controls peptide hormones in fish, revealing surprising findings about conserved genetic networks and adaptable hormone regulation. This innovative method holds promise for transforming fish farming practices and exploring ways to prolong vertebrate lifespan.
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Researchers discovered a 'sex peptide' transferred during mating that disrupts the biological clock of female Drosophila melanogaster, altering their morning anticipation behavior. The study sheds light on how sex hormones can affect an insect's internal timing.
A novel insulin-like peptide hormone, INSL3, remains consistent throughout a man's life, making it a reliable predictive biomarker for age-linked disease. High levels of INSL3 in young men correlate with a range of age-related illnesses, while low levels increase the risk of acquiring these diseases.
Researchers found that a specific carbohydrate attaches to a peptide hormone called atrial natriuretic peptide (ANP), regulating fluid balance and blood pressure. The study may lead to improved medications for high blood pressure.
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Researchers at Osaka University discovered a plant peptide hormone that controls the development of two different cell types involved in water flow through plants. The hormone binds to distinct receptors in leaves and roots, generating unique cellular structures essential for water transport.
Researchers at RIKEN have discovered a hormone-like peptide in plants that increases their resistance to excessive salt. The peptide, AT13, enhances salinity stress tolerance and can be applied as a natural supplement for crops growing in high-salt conditions.
Researchers from Kumamoto University have created a comprehensive genetic resource collection of plants with knocked out CLE peptides-encoding genes using CRISPR/Cas9 technology. This collection is expected to contribute significantly to future studies on the function of plant peptide hormones.
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Researchers at the University of Queensland have discovered modified peptides that can enhance plant growth and development. The study, published in Cell Chemical Biology, found that these peptides can regulate root development and increase productivity, leading to improved agricultural sustainability and food security.
A new bitter plant extract, Amarasate™, has been shown to activate gut peptide hormones involved in appetite regulation and suppress subsequent feeding behavior. The study found significant reductions in energy intake following ingestion of the extract.
The team used metal complexes to selectively modify peptide hormones, such as encephalin and octreotide. The resulting metal-peptide compounds could modulate the effect of naturally occurring peptide hormones, potentially leading to new remedies for pain or cancer.
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A Scripps Research Institute scientist has been awarded a $1 million grant to study adropin, a peptide hormone that may improve insulin sensitivity and treat type 2 diabetes. The research aims to explore adropin's potential role in glucose homeostasis and its application as a protein-based therapy.
Researchers studied peptide hormones in planarian flatworms to understand their reproductive output and potential link to parasitic diseases. The study found that disrupting neuropeptide processing in sexually reproducing planaria causes reproductive organs to regress.
Scientists at the University of Arizona have created melanotropin-based drugs with improved properties that can selectively target specific receptors. These compounds show promise in treating various conditions, including cancer, sexual dysfunction, and eating disorders.