Articles tagged with Longitudinal Studies
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Research reveals that children who attended day care regularly are more likely to overcome stereotypical beliefs in adulthood. Participants who spent time in day care were quicker to adjust their behavior when interacting with people of different ages.
A new study found that a high body roundness index over 6 years was associated with an increased risk of developing cardiovascular disease in adults older than 45. The study, published in the Journal of the American Heart Association, suggested that BRI may be a valuable predictor of cardiovascular disease risk.
Researchers from the University of California, Davis, present a comprehensive framework for analyzing longitudinal activity and behavior. By employing advanced statistical techniques, they explore the relationship between activity and age-at-death in Mediterranean fruit flies, shedding light on potential links to human lifespan.
A new large-scale longitudinal study will investigate the environmental, lifestyle, social, and clinical factors affecting brain development in children with type 1 diabetes. The five-year study aims to refine clinical guidelines and targeted treatments for children with diabetes.
A new study found that childhood trauma can have specific consequences for biological health and risk of developing 20 major diseases later in life. The study's findings differ by sex and type of stressor, highlighting the need for a precision medicine approach based on patients' sex and specific stress profile.
Researchers found that women exposed to higher levels of nitrogen dioxide and inhalable particulate matter during the second trimester face an almost fourfold increased risk of postpartum depression. The study also discovered a sustained effect of air pollution on symptoms of depression for up to three years after birth.
New research reveals Scotland's care system is taking years to find permanent homes for over 1,800 vulnerable children, with 91% experiencing maltreatment before being taken into care. Many children have no contact with their siblings, and crucial information is often missing from administrative data.
A new study analyzed data from over 700 Swedish children, finding associations between gender nonconformity and autistic traits, behavioral difficulties, and peer relationship problems. Higher levels of nonconforming play were linked to increased behavioral challenges in both sexes.
A longitudinal cohort study found differential susceptibility and resilience for mental health problems during the pandemic associated with prepandemic mental health and sociodemographic characteristics. The study's findings have implications for recovery and may provide novel insights into causes of youth mental health problems.
A recent study published in JAMA Psychiatry found that children with persistently raised inflammation are at a higher risk of experiencing serious mental health disorders, including psychosis and depression, in early adulthood. The research also discovered that those who experienced inflammation at a young age were more likely to devel...
A new study found that married men are twice as likely to age optimally compared to never-married men, while never-married women fare better than those who experience widowhood or divorce. Lifestyle factors like physical activity and healthy habits also play a crucial role in maintaining optimal health in later life.
A study of 12,000 Canadian respondents aged 65+ found that socially independent older adults born in Canada are most satisfied when living solo, while socially dependent immigrants who live alone experience lower life satisfaction. Personality-based social dispositions play a key role in how older adults feel about their living arrange...
Research reveals that children with psychiatric disorders in 2017 faced more severe challenges and reduced support from societal factors compared to previous generations. The study highlights the need for further research into why this trend has occurred, aiming to provide necessary support and prevent future negative trends.
A prospective cohort study found that both chronic and new anxiety were associated with a higher risk of developing dementia. The presence of chronic anxiety was linked to a 2.8-time higher risk, while new onset anxiety was associated with a 3.2-time higher risk.
A new study from the University of Eastern Finland found that children's exposome scores, measuring environmental and lifestyle factors, are associated with altered serum levels of 31 metabolites. These metabolites were linked to cardiometabolic diseases such as obesity and type 2 diabetes in later life.
The COVID-19 pandemic exacerbated ongoing declines in longitudinal continuity of care within English general practices, according to a recent study. Factors linked to greater appointment availability predicted slower declines in continuity levels.
A new study suggests that even temporary increases in drinking can have lasting effects on bipolar symptoms, but the opposite isn't true. The research found that individuals with bipolar disorder who drink more than typical for them are more likely to experience an increase in depressive and/or manic symptoms over six months.
A new study published in Nature Communications found that smoking is a key lifestyle factor contributing to cognitive decline among older adults. Non-smokers who engaged in healthy behaviors such as regular exercise, moderate alcohol consumption, and social activity experienced significantly slower cognitive decline compared to smokers.
Researchers developed machine learning models predicting upper secondary education dropout from kindergarten age, using a 13-year longitudinal dataset. The study marks an advancement in early automatic classification, potentially leading to transformative changes in educational systems and policies.
A study found that individuals with stable employment have better identity synthesis and experience less identity confusion compared to those with unstable employment. Those with higher identity synthesis also report higher life satisfaction regardless of employment status.
Researchers developed a new approach to understanding health by leveraging social media data, creating the largest cohort study in medical history. The study found that 27% of participants made an attempt to quit vaping during the study period, with a success rate of 26%, and identified key factors influencing cessation journeys.
Researchers found that many bacterial strains present in infants at 3 weeks, months, and 12 months originated from the father, not the mother. This discovery highlights the importance of physical and social interactions between newborns and their fathers, as well as with other family members.
A recent study published in JAMA Network Open found a positive association between heavy lifetime cannabis use and cardiovascular disease mortality among female participants. The study suggests that long-term cannabis use may have negative effects on mortality rates, highlighting the need for further research.
A new study by UCL researchers found that socially connected older people experienced a sharper drop in quality of life and life satisfaction during the pandemic. In contrast, more isolated adults experienced a greater decline in loneliness but similar levels of life satisfaction.
A study in Seattle found a small but significant reduction in body mass index (BMI) among children living in areas with a sweetened beverage tax compared to nontaxed areas. The results support the effectiveness of such taxes as a policy for improving children's BMI, building on existing US studies.
A new study found significant differences in brain development between autistic boys and girls, with autistic females showing a thicker cortex at age 3 and faster cortical thinning into middle childhood. The findings highlight the need for longitudinal studies that include both sexes to better understand sex-specific changes in autism.
A longitudinal study of LGBTQ+ youths found that transitioning gender identities is not associated with depression. Instead, higher rates of depression were linked to bullying and victimization. The study followed 366 young people ages 15-21 and measured depressive symptoms periodically over three years.
A new study published in Addiction journal found that high-potency cannabis use between 16 and 18 doubles the risk of psychotic experiences from 19 to 24. Researchers analyzed data from the Children of the 90s study, which tracked over 14,000 individuals from birth to age 24.
A longitudinal pilot study monitored musculoskeletal and joint health of NBA G League players over a professional basketball season. The study used wearable technologies and advanced imaging techniques to correlate training loads with structural and functional changes in the knee joint.
A groundbreaking study found that areas of age-related damage in the brain relate to motor outcomes after a stroke, suggesting other factors are at play. White matter hyperintensities were associated with more severe motor impairment, independent of corticospinal tract damage.
A new study found that loneliness grows as people age, with a U-shaped pattern of higher levels in younger and older adulthood. Factors associated with persistent loneliness include social isolation, lower education, income, and functional limitations, as well as being divorced or widowed, a smoker, or having poorer health.
A new study assesses cognitive impairment over time in adults with essential tremor, finding a cumulative prevalence of 26.6% for mild cognitive impairment (MCI) and 18.5% for dementia. Early detection is crucial to slow further cognitive decline and improve quality of life.
A new study from the University of Houston reveals that adolescents' life goals, particularly those related to education and prestige, have a significant impact on their educational attainment and occupational outcomes. As people grow older, these goals tend to become more important, with changes in them predicting later success.
Middle-aged and older adults believe that old age begins later in life, with increased life expectancy contributing to this shift. The study found that participants born in different years reported a later perceived onset of old age, but the trend has slowed in recent years.
Health behaviors in middle adulthood are relatively stable throughout adulthood, with positive changes observed during the 19-year follow-up period. Sociodemographic characteristics and personality traits, such as conscientiousness and agreeableness, significantly influence healthier behaviors.
A new study found that non-medical cannabis use is significantly associated with a 96% decrease in odds of subjective cognitive decline. However, medical and dual-use were not significant in reducing the risk of SCD. The study highlights the potential protective effects of cannabis on cognition, but more longitudinal research is needed...
A study published in PLOS ONE found that employees with volatile work schedules early in their career had worse sleep and more depressive symptoms at age 50. The study used data from the National Longitudinal Survey of Youth-1979 to examine the impact of employment patterns on health in middle age.
The study reveals that smartphone-based cognitive assessments can provide reliable and valid results for diagnosing frontotemporal lobar degeneration. These findings suggest a scalable solution for remote evaluations, which may enhance early detection.
A study of 1,156 individuals aged 50+ found that those with more musculoskeletal pain complaints tended to retire earlier than pain-free participants. Chronic pain was also linked to a higher risk of ceasing work sooner, even after controlling for other factors.
A study of 3,000 middle-aged and older women found that those who perceived gender discrimination reported declines in wellbeing over time, including more depressive symptoms, loneliness, and lower quality of life. Perceived sexism was linked to depression, loneliness, and poor life satisfaction six years later.
A new study led by Worcester Polytechnic Institute aims to determine whether AI can help doctors predict which patients will benefit from mindfulness-based stress reduction in managing chronic lower back pain. The research uses machine learning and physiological data from fitness sensors to detect patterns that may not be apparent to d...
Researchers investigated the impact of senolytic treatments on DNA methylation clocks and epigenetic age. Results showed significant increases in epigenetic age acceleration with Dasatinib and Quercetin treatment, but not with Fisetin addition.
A new study of 488,000 Finnish mothers found that those with healthy, near-by grandparents were less likely to take antidepressants. In contrast, antidepressant use was highest among mothers whose grandparents were elderly and lived far away due to stress from caring for them.
Weight loss treatments such as nutrition counseling and bariatric surgery increased the patient-level probability of achieving significant weight loss. Current treatment utilization rates are insufficient to impact the population level, highlighting a need for improved access.
Researchers analyzed data from the English Longitudinal Study of Ageing and found that public spending cuts during austerity (2012-2018) led to a steeper increase in frailty with age compared to pre-austerity period. This association was observed across all population groups, but particularly among the oldest people.
A longitudinal study found that higher consumption of tea, processed meats, and food prepared outside the home is associated with increased levels of PFAS in the body over time. This suggests potential solutions for protecting the public from these harmful chemicals.
A new tool, developed with a machine learning-based approach, can predict diuretic response in patients with ADHF. The BAN-ADHF score may lead to personalized strategies for effectively managing congestion in hospitalized patients.
Persistent withdrawn and somatic symptoms in adolescence increase the risk of suicidal thoughts in mid-adolescence. The study found that these symptoms persist or increase over time to be particularly concerning for suicidal risk.
A study from Dana-Farber Cancer Institute found that unintentional weight loss is associated with an increased risk of cancer diagnosis within the coming year. The research suggests that patients experiencing unexpected weight loss should see their doctor to consider possible causes, including cancer. Healthy weight loss can come from ...
A recent study published in NeuroImage found that physically active individuals experienced less decline in entorhinal cortex thickness over a seven-year period. Cognitive reserve is also boosted through regular mental stimulation, suggesting that brains can be trained like muscles to counteract age-related decline.
A new study published in the Journal of the American Heart Association found that many couples around the world share high blood pressure. The research analyzed data from over 50,000 couples in four countries and found a strong association between partners' blood pressure status.
A longitudinal study of Hispanic adolescents and young adults found that PFAS exposure is linked to lower bone mineral density and a higher risk of osteoporosis. The study's findings highlight the need for stricter regulation of PFAS to protect vulnerable populations.
A long-term study published in Environmental Epidemiology shows a slightly increased incidence of cancer, particularly colon, pancreas, and stomach cancer in men, as well as lymphoma in women. The researchers used new calculation methods to analyze radiation doses from Chernobyl fallout.
A longitudinal study found that nine-to-10-year-old children who drink daily caffeinated soda are twice as likely to try alcohol within a year. Daily caffeine intake is associated with low working memory and high impulsivity, recognized risk factors for substance use disorders.
A Singapore study found that drinking coffee and tea at midlife is associated with reduced likelihood of physical frailty in late life. The study, led by Professor Koh Woon Puay, analyzed data from over 12,000 participants aged 45-74 years old.
Researchers are investigating gastrointestinal symptoms, specifically irritable bowel syndrome, as a condition of long COVID using a $3.2 million grant. The study aims to better evaluate and treat COVID-19-related IBS by analyzing data from the Arizona CoVHORT research study.
A new study published in The Lancet Public Health found a small increased risk of depression and anxiety among higher education students compared to their peers. By age 25, the difference had disappeared between graduates and non-graduates.
The Keck School of Medicine of USC has launched a five-year, $50.3 million multi-omics study to better understand the causes and prevention of various diseases, including NAFLD, in underrepresented racial and ethnic groups.
A new study from Aarhus University found that acute kidney injury causes significant cell death in kidneys, which then spreads to healthy tissue over several days. This finding may increase the risk of patients developing chronic kidney damage and highlights the need for timely intervention measures.
A new study found that older adults with COPD had a heightened risk of depression during the early stages of the COVID-19 pandemic. Approximately 1 in 2 individuals with COPD and a pre-pandemic history of depression experienced a recurrence of depression.