Articles tagged with Academic Journals
Researchers found that blood cancer cells rewired their gene regulatory networks to evade drug treatment in Acute Myeloid Leukemia (AML), disrupting normal differentiation and growth. The study identified key findings, including changes in open chromatin regions and the loss of binding of RUNX1 and AP-1 transcription factors.
Jan-Benedict E.M. Steenkamp, a renowned marketing expert, has been selected as the next Editor-in-Chief of the Journal of Marketing, effective July 1, 2025. With his extensive research experience and leadership skills, Steenkamp aims to expand the journal's tradition of high-quality research.
Researchers used a mouse model to assess the impact of senolytic agents dasatinib and quercetin on pelvic organ prolapse. The study found that D+Q injections did not result in significant differences in prolapse development but reduced cellular senescence markers.
Researchers humanize the lupus-derived autoantibody 3E10, preserving its therapeutic efficacy, to create novel cell-penetrating antibodies targeting tumors and RAD51. Humanized variants exhibit faster cell uptake and superior in vivo tumor targeting.
Researchers reported a complete and long-lasting response to immunotherapy in a stage IV non-small cell lung cancer patient with brain metastases. The patient achieved overall survival of 87 months and progression-free survival of 73 months after treatment sequencing.
A new study found that fibroblast growth factor 21 (FGF21) is an independent predictor of all-cause mortality in older adults. The Polsenior2 study revealed that middle and high FGF21 levels were associated with increased mortality risk, particularly when adjusted for age, co-morbidities, and blood parameters.
A new article in Journal of Palliative Medicine highlights the growing role of for-profit entities in home health and hospice care, which can compromise care quality and patient welfare. The authors emphasize the need for research and regulatory responses to address these trends and ensure better care for seriously ill older adults.
Research highlights molecular chaperones' role in maintaining tumor suppressor stability and functional integrity. This understanding is crucial for developing targeted therapies for multiple cancers.
A first-of-its-kind study assesses how closely patients' perceptions of network adequacy align with those of insurers. The survey found strong support for definitions related to timely access, specialty care, and mental health care, as well as broader concepts like public transportation access and cultural competency.
TP53 mutations are commonly associated with therapy-related AML and complex cytogenetics. Researchers found improved long-term outcomes when allo-HCT was performed during Complete Remission 1 (CR1), despite limited effective therapies for TP53-mutated AML.
A study found that more than half of the top US physicians who reviewed research for major medical journals received industry payments, with most being for research purposes. The payments may have implications for conflicts of interest and research outcomes, highlighting a need for transparency in the medical publishing system.
Researchers identify modifiable determinants of cerebral blood flow (CBF) and arterial transit time (ATT) in older adults. A higher BMI was associated with lower CBF and longer ATT, while cardiorespiratory fitness linked to longer ATT in specific brain regions.
The latest APA journal issues explore schizophrenia spectrum disorders, PTSD treatment, and college mental health. Research highlights include new approaches to psychosis treatment and findings on mental health in higher education.
The expert panel discussion sheds light on the best practices for injecting hyaluronic acid (HA) fillers in the infraorbital hollows. Top surgeons share their preferred fillers and techniques, providing valuable insights for treating undereye dark circles.
A new study by Tel Aviv University reveals that 27% of respondents withhold inventions due to reasons such as emotional attachment, fear of credit, or lack of trust in management. The study aims to shed light on this phenomenon and develop effective management tools to increase employees' willingness to disclose their inventions.
Early-stage HR+ breast cancer survivors experience weight gain, particularly those with healthy BMI or overweight at diagnosis. Black women have higher rates of obesity and related comorbidities compared to White women, leading to a 40% higher breast cancer mortality rate.
Researchers found that colleges offer multimillion-dollar coaches instead of throwing money at student-athletes, leading to an arms race in athletics. The study revealed a significant correlation between head coach salaries and team recruitment success, with higher salaries associated with better teams and more victories.
A new study found that patients with 4 or 5 identified risk factors, including age 18-24 years and schizophrenia spectrum disorders, had over 100 times the incidence of Neuroleptic Malignant Syndrome. The data provide a basis for early identification and monitoring of children and youth at elevated risk.
Researchers from the University of California, Davis, present a comprehensive framework for analyzing longitudinal activity and behavior. By employing advanced statistical techniques, they explore the relationship between activity and age-at-death in Mediterranean fruit flies, shedding light on potential links to human lifespan.
A University of Oklahoma researcher found that menthol cigarettes are more addictive and appealing than non-menthol cigarettes, especially among racial and ethnic minorities and the LGBTQ population. Participants were willing to work harder for puffs of menthol cigarettes, indicating a heightened risk of nicotine dependence.
A study published in the journal Brain shows that increases in protein levels with new Alzheimer's drugs can explain the slowing of cognitive impairment at least as well as the reduction in amyloid plaques. The researchers found that higher levels of a critical brain protein correlate equally well with cognitive benefits.
A noninvasive ultrasound technology called Break Wave lithotripsy (BWL) was found to be highly effective in treating urinary stones, with an 88% fragmentation rate. Patients were able to undergo treatment without anesthesia and had a high success rate of being completely stone-free after follow-up CT scans.
A new study from the University of Notre Dame finds that Big Tech privacy policies can decrease consumer engagement and satisfaction with ads, leading to reduced performance and revenue. The study explores how data minimization and other policies affect ad variety and consumer behavior.
A new library of healthy participants' neuroimaging data has been created to aid in the diagnosis and treatment of traumatic brain injury (TBI). The Normative Neuroimaging Library consists of data from approximately 1900 individuals, providing a comprehensive dataset for clinicians and researchers.
A machine-learning algorithm called xFakeSci has been developed to detect AI-generated scientific articles, with a success rate of nearly 94%. The tool analyzes word patterns and bigrams to distinguish between real and fake papers, highlighting the need for comprehensive detection methods as AIs become increasingly sophisticated.
New research from Bayes Business School finds that launching new technologies requires strategic timing to succeed. The study identifies four timing situations that can confront marketing managers, offering a framework to develop a launch strategy leading to success.
Experts propose a series of scientific principles and experimental approaches to assess potential carcinogenicity of gene therapies. Data transparency is crucial, with publicly accessible data from viral integrations site studies and clinical settings.
Researchers have developed a cost-effective and easily reproducible point-of-care testing device that can accurately measure cortisol levels in the blood. The device uses iridium oxide nanoparticles to improve stability, sensitivity, and selectivity, allowing for commercial use.
Researchers have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine disease. The treatment approach may represent a potential long-term universal treatment for MSUD.
Research reveals that stronger brands benefit from individual salesperson incentives, while weaker brands see increased profitability with group incentives. The study explores the impact of brand strength on sales incentive choices.
A recent study published in PLOS Biology investigated the effectiveness of eLife's standard wording for evaluating scientific article importance. The research, conducted online, revealed that participants' implied rankings often diverged from the intended meaning.
The African American Transplant Access Program aims to mitigate disparities in solid organ transplantation, while a physician-created platform speeds clinical decision-making. NEJM Catalyst also explores quality and safety improvement through longitudinal care management for diabetes and hypertension.
A new study found that mTORC1 activity correlates with classical biometrics, such as height and macrocephaly, as well as specific neuropsychiatric diseases like anxiety and autism. The research suggests that human variability of mTORC1 gain of function may predict medication response.
A new study found that meeting partners online is positively linked to relationship success among those who have social media presence on their relationships. However, the link was absent among individuals without this social media presence, particularly in marital relationships.
Researchers discovered that buyers are more likely to choose and pay more for products made with enjoyment, even when sellers charge lower prices. Sellers' production enjoyment signals quality and leads to higher buyer interest.
The new guidelines from the Surgical Infection Society offer updated recommendations for antimicrobial agent selection, source control, and treatment of specific pathogens. These evidence-based guidelines aim to improve clinical outcomes and reduce mortality rates from intra-abdominal infections globally.
A large-scale egg freezing study in London found consistent, predictable, and reliable success rates comparable to those of routine IVF. The 15-year study followed up on almost 30,000 eggs frozen between 2008 and 2022, with a live birth rate per embryo transfer of 26%.
The IADR and AADOCR published the revised OHStat guidelines to improve reporting in oral health research, incorporating CONSORT, STROBE, and SAMPL guidelines. The guidelines also recommend estimating results in clinically meaningful units using confidence intervals, rather than relying on P values.
A new study introduces a novel hypothesis that digital technologies affect human sociality and mental health, particularly among youth. The Disembodied Disconnect Hypothesis suggests cultivating rich personal relationships in face-to-face communities to counterbalance disembodied digital interactions.
The article reviews recent advances in applying artificial intelligence to oncology, showcasing promising improvements in cancer care. The authors emphasize the need for interdisciplinary collaboration, rigorous validation, and ethical principles to harness AI's potential.
The West Virginia University athletic training researcher developed a new national position statement on emergency action plan development and implementation in sports. The recommendations aim to reduce catastrophic injuries by designating an emergency action plan coordinator who collaborates with other athletic staff.
The study expands the Correlates of War Project's Militarized Interstate Dispute Data, adding new data spanning 2014-2024 and launching MID Live, an early detection mechanism for interstate hostilities. This helps inform security policies and strategies by analyzing evolving patterns of conflict and competition between states.
A new study reveals that a cancer drug can improve insulin sensitivity and lower blood glucose levels, but eliminating a specific gene related to fat metabolism worsens insulin resistance. The research highlights the interconnectedness of fat metabolism in organs and the need for simultaneous treatment of obesity and insulin sensitivity.
A new study reveals that traumatic intracranial aneurysms are more common and associated with intracerebral hematomas after civilian gunshot wounds, challenging conventional wisdom. Spontaneous resolution occurs in approximately 40% of patients.
The Society for Academic Emergency Medicine (SAEM) has released a new guideline for managing nonopioid use disorders in emergency departments. The guidelines provide evidence-based recommendations for evaluating and treating conditions such as alcohol withdrawal syndrome, alcohol use disorder, and cannabinoid hyperemesis syndrome. The ...
A new study published in Journal of Neurotrauma found that more than 30% of patients with traumatic brain injury who underwent withdrawal of life-sustaining treatment recovered at least partial independence. The study suggests that a lifetime in a vegetative state or severe disability is not a common outcome even after a serious injury.
The Academic Payvider model enhances value-based care by fostering improved coordination, reduced insurance hassles, and increased staff attention. This joint approach between payers and providers aims to drive complex care down through innovative reimbursement structures.
A new study reveals that women make up just 13% of the American Academy of Facial Plastic and Reconstructive Surgery membership. The authors highlight the need for education, mentorship, and sponsorship to address these disparities and promote a more inclusive future for female surgeons.
A recent study published in Attention, Perception & Psychophysics found a correlation between pupil dilation and working memory. Researchers at the University of Texas at Arlington discovered that individuals with better working memory had larger pupil dilations during tasks, indicating improved focus and attention.
A new study developed two machine learning models to quantify CD8+ cell positivity and classify the immunophenotype of cancer specimens in patients with non-small cell lung cancer. The models hold promise for identifying patients who may benefit from immunotherapy.
Two new Review articles explore AI's application in early cancer detection, highlighting its potential to enhance diagnostic accuracy and improve treatment selection. The articles emphasize the need for a robust, multi-disciplinary approach to integrate AI into medicine.
A new study presents a novel surgical technique for treating Moebius syndrome, a rare condition that prevents smiling and affects social engagement. The technique involves utilizing the ipsilateral facial nerve to power gracilis free functional muscle transfer in select patients with residual facial nerve activity.
Researchers developed two models to evaluate personal learning performance, combining biometric responses with demographic data. The simplified forecast model showed higher accuracy and reduced overfitting than the full forecast model.
A recent study reveals that over one-quarter of older transgender adults have seriously contemplated ending their lives, highlighting the urgent need for targeted support and interventions. The study found that experiencing challenges in areas such as workplace issues and personal safety significantly increased the odds of contemplatin...
Dr. Sonia Hernández's recent publication in the Journal of American History explores the complex histories of violence, gender, and power dynamics along the US-Mexican border region from 1900-1913. Her research centers on the testimonies of Mexican-origin women, shedding light on complicated gendered negotiations with state agents.
Research from TU Dortmund University and RWTH Aachen University suggests that marketing academia has focused on identifying new phenomena, but neglected building 'big-picture' frameworks and theories. This limits the field's ability to provide answers to complex marketing problems.
The MIT Press is expanding its shift+OPEN initiative with a $275,000 NSF grant to flip two high-impact subscription-based journals to diamond OA. The program aims to accelerate STEM and HSS research by providing barrier-free access to scholarly works.
The program gives medical students clinical responsibility, including observing anesthesia administration, to form a picture of their future career. It translates to more anesthesiologists, with 55% of participants choosing anesthesia as their specialty after the externship.
A University of Trento study has demonstrated that inorganic structures can incorporate organic molecules to form primitive cell-like membranes, a key step in the origin of life on Earth. The findings open up new research opportunities for recreating life on other planets and improving drug effectiveness.
A meta-analysis of multiple studies found no association between depression and anxiety and most types of cancer. However, the study found a link between depression and anxiety with a 6% higher risk of developing lung cancer and smoking-related cancers.