News on open-access publishing and its reach. Covers journal launches, open-access agreements, and research made freely available.
In 2024, MDPI published 238,000 peer-reviewed open-access articles, tripling its research integrity team size. The publisher expanded its global workforce to 6,650 staff across 21 offices, publishing more than 25 million downloads of fully open-access research.
The new Individual-based Ecology journal publishes its first articles, offering a fresh perspective on how individual organisms and ecological systems dynamics are linked. The journal focuses on individual-based perspectives in ecology, complementing other ecological disciplines.
A new review highlights how breast cancer cells change their communication and growth patterns, helping tumors survive, spread, and resist treatment. The review explores disrupted signaling pathways, including PI3K/Akt/mTOR and RAS/RAF/MEK/ERK, which can promote tumor progression and resistance to treatment.
A new study found that treating aged mice with montelukast improved retinal health by reducing inflammation and boosting proteasome activity. This approach may offer a promising new way to slow age-related vision loss and protect eye health in older adults.
A new editorial highlights a growing concern in cancer care: radiotherapy may leave behind residual disease that can lead to worse long-term outcomes. Studies have shown that patients with residual disease are more likely to experience cancer recurrence and shorter survival, emphasizing the need for regular biopsy-based tests.
The AI FORA project analyzed how AI-based social assessment varies across nine countries and four continents, highlighting the need for flexible, dynamic, and adaptive systems that reflect social stakeholders' perspectives. The research aims to improve AI in addressing fairness and discrimination issues in public social services.
Marine animals are being used to gather valuable data on human impact on the ocean. Biologging, attaching sensors to wild animals, provides insights into environmental conditions and behaviors. The goal is to develop an 'Internet of Animals' with shared standards for data sharing, enabling targeted policies and a sustainable coexistence.
This study found that aging impacts the gut microbiome composition and metabolites differently in male and female rats, influenced by biological sex and mitochondrial DNA. The researchers analyzed fecal samples from genetically diverse rats to assess bacterial changes with age, revealing more significant shifts in females.
The WIN Consortium is transforming cancer care through personalized medicine, leveraging AI, molecular profiling, and clinical trials. The organization's innovations, including N-of-1 clinical trials and WINTHER and WINGPO trials, are helping clinicians make more precise treatment decisions and improving outcomes for cancer patients.
Breast cancer survivors experience accelerated aging due to detrimental effects of BC and its treatments, particularly systemic therapies. The study highlights the need for ongoing monitoring and potential strategies to slow down aging in cancer survivors.
Impact Journals is proud to exhibit at the AACR Annual Meeting 2025, featuring its esteemed journals Aging-US, Oncotarget, Oncoscience, and Genes & Cancer. The meeting highlights significant advancements in cancer research, aligning with Impact Journals' mission to disseminate impactful scientific research.
Cranfield University has renewed its flat fee partnership with Frontiers for 2025, empowering researchers to publish without article processing charges. This collaboration simplifies budgeting and reduces administrative tasks, supporting open-access principles and promoting sustainable publishing strategies.
A new study suggests that statins can reduce chest muscle loss in smokers, while aspirin may contribute to increased muscle loss. The study examined data from 4,191 participants and found that statins protected pectoralis muscle area and density, whereas aspirin led to decreased muscle mass.
Researchers have created quantum holograms using metasurfaces and nonlinear crystals, enabling precise control over entangled information. The technology holds promise for practical applications in quantum communication and anti-counterfeiting, with potential to increase information capacity and reduce system size.
Recent research suggests that some invasive cancers diagnosed in early-stage breast cancer may not need immediate surgery, highlighting the importance of more precise screening methods for DCIS. The COMET trial found that at least half of invasive breast cancers take years to progress or may never progress at all.
Research from the Long Life Family Study found individuals from long-lived families have significantly better vascular health than the general population. The study identified key risk factors and four genomic regions linked to PAD risk, providing novel insight into underlying mechanisms.
Genetic changes triggered by environmental factors like pollution, diet, and stress can increase cancer risk. Nearly everyone is exposed to cancer risk factors daily, highlighting the need for public awareness and policy action to reduce exposure.
A new study found that people with chronic obstructive pulmonary disease (COPD) and arthritis have a significantly increased risk of death compared to those with only arthritis. The research analyzed data from over 11,000 individuals in the US and discovered a strong association between COPD and mortality rates in people with arthritis.
The Biodiversity Data Journal has launched its own data portal on GBIF, providing seamless access to nearly 300,000 biological organism occurrences. The portal also offers direct access to over 800 datasets and 1,000 citations of associated journal articles.
Researchers found that PRP treatment increased gene expression related to metabolism, cell survival, and communication between cells in cumulus cells. This suggests that PRP may help support egg development and fertility in women with poor ovarian response.
The University of Kansas and Frontiers are renewing their partnership to provide seamless, cost-free publishing opportunities for KU researchers in all Frontiers journals. The flat fee model delivers predictable costs, reduced administrative responsibilities, and full support for open-access principles.
This theme issue explores digital health solutions to address social isolation, health literacy, and cultural influences on aging health. Contributors are encouraged to submit their work by September 30, 2025.
A new study highlights the importance of diagnosing depression and anxiety in people with chronic obstructive pulmonary disease (COPD) to address gaps in care. The study found that fewer than half of those meeting the criteria for a depression or anxiety diagnosis were receiving mental health counseling or using antidepressants.
A study published in Aging (Aging-US) found associations between several environmental exposures and epigenetic aging in a large sample of US adults. Cadmium, lead, and cotinine were linked to faster biological aging, increasing the risk of age-related diseases such as heart disease and cancer.
The Aligning Science Across Parkinson’s (ASAP) initiative offers funding of up to $6M for research community members to develop sustainable tools for Parkinson’s disease research. The funding supports the development of preclinical models, detection reagents, and modulation agents to accelerate therapeutic research.
Research suggests that resistance exercise is the most effective type for tackling insomnia in older adults, with a significant improvement in sleep quality. Aerobic and combination exercises also show promise, but to a lesser extent. The study analyzed data from 24 studies involving over 2,000 adults aged 60 and above.
The partnership aims to develop comprehensive, locally driven open science frameworks through capacity building, policy advocacy, and stakeholder engagement. National open science dialogues will be instrumental in shaping the future of open science in North Africa.
A new study reveals that radiotherapy has opposite effects on glioblastoma multiforme (GBM) and low-grade gliomas (LGG), with GBM patients living longer after treatment. The study highlights the need for personalized treatment approaches based on genetic and molecular characteristics to improve survival outcomes.
Researchers discover engineered TIMP molecules can block cancer cell migration and invasion, offering a targeted approach to treating GBM. The findings also suggest the potential for safe treatment with minimal side effects.
FAIR² Data Management leverages AI-assisted curation to structure research data for publication, enhancing research efficiency and reproducibility. The platform transforms data into a tool for discovery, tackling pressing challenges in global health, sustainability, and scientific innovation.
BaCell 3D conference to feature original research in organoids and regenerative medicine, published in Stem Cell Reports. The International Society for Stem Cell Research (ISSCR) partners with Stem Cell Reports to promote discoveries with potential to transform regenerative medicine.
Researchers from Yale University and Altos Labs have identified age-invariant genes that stay the same across all tissues during aging. These genes are linked to essential cellular functions, challenging the common belief that gene dysregulation drives aging.
Researchers across Germany can now publish unlimited articles without APCs, leveraging Frontiers' flat fee model. The renewed agreement simplifies submission processes and enhances career opportunities with increased visibility of open-access research.
Researchers have discovered several novel downstream p53 targets that could lead to improved cancer therapies. The study highlights the critical role of p53 in preventing cancer and identifies two new genes, ALDH3A1 and NECTIN4, as potential targets for cancer treatment.
A new test called EpiAgePublic estimates biological age using only three DNA sites in the ELOVL2 gene, simplifying traditional methods while maintaining accuracy. The study found that EpiAgePublic accurately tracks aging patterns and can identify factors accelerating the aging process.
A study found that pro-inflammatory molecules contribute to benign prostatic hyperplasia (BPH) in aging men, especially those with metabolic syndrome. Men with BPH had higher levels of pro-inflammatory markers and lower anti-inflammatory substances, suggesting a link between inflammation and prostate conditions.
A rare case of adenomyosis in an 81-year-old postmenopausal woman closely resembles invasive endometrial cancer, emphasizing the challenges of diagnosing this condition. Further studies are needed to refine diagnostic protocols and determine risk factors for postmenopausal patients.
Researchers found that a combination of Panitumumab and low-dose Capecitabine is an effective and well-tolerated maintenance regimen for patients with wild-type KRAS metastatic colorectal cancer. The treatment delayed disease progression while managing side effects, improving patients' quality of life.
ABT-263 eliminates harmful aging cells in the gut, reducing inflammation and lowering cancer risk in a mouse model of GI cancer. The study suggests that removing senescent cells could help prevent radiation-related GI cancer, highlighting the potential of senolytic drugs as a preventive treatment.
The flagship journal of the International Mycological Association has been published on the new ARPHA platform by Pensoft. The first ten manuscripts have now been published, featuring a broad spectrum of mycological subdisciplines and including articles on fungal evolution, ecology, and conservation.
Osteosarcoma cells often have extra copies of the SETDB1 gene, making the cancer more aggressive and harder to treat. Blocking SETDB1 may help the immune system recognize and attack osteosarcoma cells, offering a promising new way to treat this type of bone cancer.
The journal of the Italian Society of Vegetation Science has changed its name to Vegetation Ecology and Diversity, launching a new website and introducing new Topical Collections. The journal now offers publication fee waivers and discounts for young researchers.
A rare case report highlights the association between systemic mastocytosis and severe osteoporosis in a young adult patient, emphasizing the importance of early diagnosis and consideration of SM as an underlying cause. The study aims to raise awareness about this underrecognized condition and its potential impact on bone health.
The expanded partnership makes it easier for researchers to discover OA funding opportunities through Taylor & Francis OA agreements. Researchers can now explore an additional 178 titles, including unique journal profiles and enhanced discoverability on ResearchGate.
A study found that DNA methylation clocks used in forensic science and epigenetics are less reliable when applied to non-blood tissues, such as lungs, colon, and kidneys. The researchers suggest that organ-specific epigenetic clocks may be needed to improve biological age prediction.
A new research paper found that physical activity (PA) is associated with better sleep quality in older adults during social isolation. Reduced levels of PA had a negative association with the quality of sleep in four studies, while one study found improved sleep patterns among active individuals.
A new case report reveals a rare and aggressive form of leukemia developing from donor cells nine years after a stem cell transplant. The disease, driven by genetic mutations in key genes, progresses despite intensive treatment and ultimately proves fatal.
The Sikt and Frontiers national open access agreement has been renewed for 2025, benefiting 36 Norwegian institutions. Researchers at these institutions can enjoy a simplified publishing model with national discounts on article processing charges.
A new genetic mutation, RUFY1-RET fusion, was discovered in a patient with stage IV CD-74-ROS1 fusion NSCLC who developed resistance to lorlatinib. The finding highlights the importance of ongoing genetic testing to guide therapy decisions.
The KeyScope is a low-cost, robust laparoscope priced at approximately $1,000, making it accessible in low- and middle-income countries. It offers high-resolution images, color accuracy, and low distortion, comparable to standard laparoscopes.
A team of researchers recommends incorporating principles like collective benefit and ethical governance into ecological data practices to align with existing data infrastructures. They suggest establishing collaborative relationships with Indigenous rights holders and exploring how data can be aligned with Indigenous expertise and wor...
A study found clear differences in brain health between Hispanic and non-Hispanic White older adults, with Hispanic participants scoring lower on tests of memory, attention, and problem-solving despite similar mental health. Researchers emphasize the importance of considering social, economic, and cultural factors when developing progr...
A large study found pregnant women with cervical cancer face higher health risks during pregnancy and childbirth, including premature birth and cesarean sections. However, the babies' health is largely unaffected, with no significant differences in birth defects or stillbirths.
Researchers discovered that a topical ABT-263 treatment effectively reduces aged skin senescence markers, priming the skin for improved subsequent wound healing. The treatment also triggered inflammation, which surprisingly helped the healing process by 'waking up' the skin's repair systems.
The partnership allows Manchester Metropolitan University researchers to publish freely in all Frontiers journals without APCs, reducing administrative burdens and promoting open access. This model aligns with the institution's commitment to advancing sustainable and equitable publishing practices.
Dr. Gunther Eysenbach is stepping down as CEO of JMIR Publications to focus on innovation in academic publishing and AI-driven solutions. Sean Jeong takes over with a proven track record in digital transformation, agile delivery, and program execution.
Lifecycle Journal reimagines scholarly publishing with a community-driven approach to critically engage with research throughout the entire research lifecycle. The journal empowers researchers to share and refine their work using human-led, machine-assisted, and empirical credibility evaluations.
A new algorithm proposes measuring quadriceps muscle mass for more accurate sarcopenia diagnosis, potentially leading to earlier detection and better treatment options. Ultrasound imaging is recommended as a cost-effective and practical solution for diagnosing sarcopenia in clinical settings.
Researchers found a genetic change, pR552*, that could give the RB1 gene a new function leading to cancer growth. This challenges the common belief that both copies of the RB1 gene must be damaged for cancer to develop.
PeerJ has launched the Arctic Frontiers Hub to showcase cutting-edge research on the Arctic region, fostering a multidisciplinary community of scientists and stakeholders. The hub provides a dedicated platform for presubmissions and full submissions subject to peer review through PeerJ Life & Environment journal.