News on open-access publishing and its reach. Covers journal launches, open-access agreements, and research made freely available.
Researchers identified a novel region in AR that binds to PCNA, and developed a small peptide to mimic this region, blocking the AR-PCNA connection. This approach reduced cancer cell growth, particularly in patients with limited treatment options.
Researchers found that aging increases the brain's vulnerability to low oxygen levels, disrupting the blood-brain barrier and leading to inflammation and cognitive decline. The study identified specific oxygen levels that trigger BBB disruption, with older mice showing increased sensitivity even at mild hypoxic levels.
Researchers discovered that blocking PRDX1 protein can make ovarian cancer cells more responsive to DNA-damaging platinum therapies. The study suggests targeting PRDX1 could be a viable strategy to improve chemotherapy efficacy.
A study investigated immune-related adverse events (irAEs) in Latin American patients with advanced liver cancer treated with atezolizumab and bevacizumab. Most irAEs were mild or moderate and resolved within a month, without impacting overall survival.
A new research paper published in Aging-US identified unintentional weight loss as the strongest predictor of fall risk among Taiwanese elderly. The study found that analyzing each frailty feature individually provided more accurate predictions of fall risk than using a broad frailty label.
A 25-year review highlights the stomach cancer-fighting potential of Brazilian plant species, which contain bioactive compounds with potential anticancer properties. The studies suggest that regular consumption of fruits and vegetables rich in polyphenols and flavonoids may help lower the risk of stomach cancer.
UNAM and Taylor & Francis announce a three-year agreement to publish research articles in over 2,400 journals. This move aims to boost the global reach and impact of UNAM's research.
Researchers review clinical and scientific advances combining radiation therapy with immunotherapy to strengthen the immune response and improve disease control. The approach may offer new treatment options for patients facing hard-to-treat forms of bladder cancer.
Researchers found that consuming foods high in methyl adaptogens, such as green tea and berries, can reduce markers of epigenetic aging. The study, which involved middle-aged men, suggests that targeted food choices may help slow the aging process.
Over 16,000 Pensoft articles are now available on the BHL platform, complete with full-text PDFs and metadata. This integration enhances accessibility for researchers seeking biodiversity information.
A new DNA-based blood test using PhasED-Seq technology detects minimal residual disease (MRD) in B-cell malignancies, offering a powerful tool for early detection and monitoring treatment response. The assay demonstrates exceptional performance and high accuracy in detecting cancer cells in the bloodstream.
A nationwide cohort study found that immune checkpoint inhibitors significantly increase the risk of myocarditis in NSCLC patients, with a 7.4-fold increase in risk compared to non-users. Cardiac monitoring for at least six months following ICI initiation is recommended.
A new study found that patients using factor Xa inhibitors experienced significantly fewer cardiovascular problems than those on other anticoagulants. Researchers followed over 1,000 patients aged 80 and above for up to five years, revealing lower rates of heart failure, artery disease, and cardiovascular death.
The 'How Equitable Is It?' tool, now updated with community feedback, evaluates scholarly communication models based on seven core assessment criteria. The new version offers clearer guidance and definitions for assessing equity in publishing arrangements.
A systematic review and meta-analysis found that individuals with blood type A have a significantly higher risk of developing breast cancer compared to those with blood type O. The research, which pooled data from over 13,000 breast cancer patients and 717,000 controls, suggests an 18% increased risk associated with blood type A.
A new study published in Aging (Aging-US) Volume 17, Issue 4 has found that the drug buthionine sulfoximine (BSO) produces similar reductions in fat mass and weight gain as the sulfur amino acid-restricted diet. BSO may offer a practical alternative to difficult-to-maintain diets for treating obesity.
Researchers discovered that METTL3, an oncogene, regulates the expression of SMAD4 via miR-146a-5p in OSCC. This pathway can potentially have therapeutic implications for treating oral squamous cell carcinoma.
The Scientific Annals of the Danube Delta Institute (SADDI) joins Pensoft's portfolio as an open-access, peer-reviewed journal. SADDI publishes research in ecology, biodiversity, environmental protection, and sustainable development related to the Danube Delta and similar wetland ecosystems.
The PEARL trial found that low-dose rapamycin improved lean muscle mass and reduced pain in women, while also showing improvements in emotional well-being. The study suggests rapamycin may offer measurable benefits for physical function and overall well-being in older adults.
GigaScience Press has won the first-ever Crossref Metadata Award, recognizing its efforts in providing high-quality metadata for its journal GigaByte. The award highlights the press's commitment to making research more discoverable and accessible through rich metadata standards.
The partnership will expand open access scholarship through Direct to Open, featuring multiple package options combining content from both presses. Duke University Press brings its humanities and social sciences catalog to the program.
Researchers found that fisetin reduces calcium buildup and protects blood vessels from hardening in vascular smooth muscle cells. Fisetin's anti-calcification activity depends on the phosphatase DUSP1, which inhibits p38 MAPK.
Impact Journals will exhibit its publications, including Aging-US, Oncotarget, and Genes & Cancer, at the SSP 47th Annual Meeting. The event aims to reimagine the future of scholarly publishing and aligns with Impact Journals' mission to foster open and impactful scientific communication.
Nicolas Hubert joins Zoosystematics and Evolution as Deputy Editor-in-Chief, bringing experience and expertise in ichthyology and genetics. He will drive further development and growth of the open-access journal.
Aging-US invites submissions for a Special Collection on cellular senescence, focusing on its mechanisms, physiological and pathological functions, and clinical applications. The collection honors Dr. Judith Campisi's groundbreaking work on senescence in aging, cancer, and tissue homeostasis.
Researchers have discovered that inhibiting the metalloprotease ADAM19 can reduce gut inflammation and cell aging markers across species. The study found that blocking ADAM19 reduced gut damage and inflammation in fruit flies, mice, and human cells, offering a promising path for creating treatments to maintain healthy tissues.
A new study found that increased perceived stress can lead to worsened respiratory symptoms and decreased quality of life in individuals with chronic obstructive pulmonary disease (COPD). The study also examined the association between stress and platelet activation, oxidative stress, and systemic inflammation.
Researchers found that high-grade pre-cancer lesions triggered stronger immune responses and showed higher levels of immune-related markers PD-L1 and FOXP3. These findings suggest that HPV may begin avoiding the immune system early in infection, allowing infected cells to grow and potentially leading to cancer.
Two Taylor & Francis journals will be converted to open access for 2025, thanks to funding from collective OA agreements and read access. The Collective Pathway to Open Publishing model combines multiple funding sources to support the conversion of HSS journals.
A large-scale database of macaque behavior is driving a shift towards open science, bringing together researchers from across the globe to share data on social lives of over 3,000 individual monkeys. The platform has grown into a collaborative effort promoting culture of sharing within the research community.
A team of Singaporean scientists has released a comprehensive long-read RNA sequencing dataset, SG-NEx, to accelerate biomarker discovery and precision medicine. The dataset offers deeper biological insights into RNA complexity, enabling researchers to detect clinically relevant biomarkers and develop better treatments.
SKINdeep, a new international journal on translational dermatology and clinical studies, is now available online. The journal features original articles, reviews, and perspectives on skin diseases and their therapeutic relevance.
A study on captive olive baboons found that about a quarter exhibited accelerated aging, while another quarter showed signs of slower aging. The researchers investigated physical indicators such as walking speed and fine motor skills, but found that these changes were more closely related to chronological age than epigenetic age.
The journal will publish research exploring digital health and advance care planning for older adults, including caregiver integration and technological innovation support. JMIR Aging boasts a strong impact in the field, with a Journal Impact Factor of 5.0 and a CiteScore of 6.5.
Participants who took the supplement showed improvements in grip strength, lower body mobility, and reductions in body weight. The supplement appeared to reduce stem cell turnover, regulate immune function, and influence gene activity related to stress response.
The Frontiers Planet Prize has announced 19 National Champions from science research teams worldwide, offering transformative solutions to climate change, community health, and planetary resilience. The prize aims to fast-track innovation and global consensus on planetary health.
The American Physical Society has received the leading score among publishers participating in SCOAP3 for its investment in open science practices. The Society earned high marks in elements like data availability, article metadata, and persistent identifiers.
Researchers developed a new method to measure changes in DNA that can help predict a person's age, focusing on how random chemical tags become over time. The study found that methylation entropy predicted age as accurately as traditional methods, with an average error of just five years.
The Leopoldina discussion paper suggests establishing a diamond open access model, where journals are funded and monitored like research itself. The authors propose an application process and regular evaluation to guarantee lasting quality and transparency while reducing costs.
A new study finds that a specific genetic variation in the PTGS2 gene is associated with an increased risk of benign prostate hyperplasia (BPH) in Lebanese men. Men carrying the C version of this gene were more than twice as likely to have BPH compared to those without it.
Researchers discovered that aging causes inflammation, oxidative stress, and gene disruption in the retinal pigment epithelium, a vital layer of cells in the eye. This study provides a clearer understanding of why aging leads to eye disease and introduces a reliable laboratory model for testing new therapies.
Researchers found that GSK3β becomes increasingly active in melanoma cells during treatment, helping them survive and adapt despite BRAF inhibitors. Treating resistant cancer cells with a GSK3β inhibitor significantly reduced their growth, suggesting blocking this protein could restore sensitivity to treatment.
A study found that smaller embryos already hatching are more likely to be chromosomally normal. This insight helps fertility clinics select better embryos during IVF, particularly for women over 35 or those undergoing PGT-A.
Xiamen University has joined the Bentham Science Institutional Membership Program to enable researchers to publish Open Access at concessionary rates in Bentham Science journals. The program promotes open research and fosters scientific advancements globally.
A new editorial in Oncotarget discusses how artificial intelligence can improve liver imaging by recognizing when it might be wrong. The approach, called 'uncertainty quantification,' helps clinicians better detect liver cancer and other diseases by pointing out areas in medical scans that need a second look.
Researchers investigated why bones become less responsive to exercise with age, finding increased mtROS or decreased Atg7-dependent autophagy in osteoblastic cells do not contribute to reduced mechanoresponsiveness. Damage to the bone's osteocyte network also does not prevent a healthy bone-building response.
Researchers found that combining imipridones with radiation therapy and temozolomide slowed glioblastoma growth and prolonged survival in mice. The treatment also boosted immune responses and suppressed MGMT protein expression, making it more effective.
A new case report presents a highly unusual combination of two benign ovarian tumors: serous cystadenofibroma and collision lesions. Accurate preoperative diagnosis is critical for effective treatment planning, and this case emphasizes the need for personalized evaluation of each ovarian mass.
Researchers found that NSD2 helps maintain MM cell identity by reorganizing DNA and influencing gene activity. This discovery could shape future treatment approaches for patients with t(4;14) myeloma.
The partnership streamlines access to biodiversity data, enabling users to search and refine queries based on various criteria. Pensoft's hosted portals provide a scalable solution for 30 journals, fostering greater connectivity between scientific research and evidence.
Three Taylor & Francis journals will be published open access in 2025 volumes with no cost to authors. Institutional support has reached the required threshold for the Subscribe to Open pilot, enabling OA publishing.
IOP Publishing is introducing a new policy for two environmental research journals, ERFS and ERCL, requiring authors to publicly share research data underpinning articles. The policy aims to foster greater access to research data and cultivate transparency and trust in science.
Researchers discovered senolytics can target Alzheimer's disease-associated brain enzymes AChE and BChE without affecting healthy ones. This selective approach may lead to safer treatments that improve memory and reduce inflammation in older adults.
The Public Library of Science and the Society of China University Journals have formed a strategic partnership to promote open access, open science, and research integrity. The collaboration aims to increase awareness of open science principles and enhance research quality in China.
Researchers at Cornell University discovered that the FGR protein can induce cell differentiation in leukemia cells similar to retinoic acid treatment. The presence of FGR alone was enough to make these cells mature, producing well-known markers of maturation and expressing inhibitor of the cell cycle p27.
All articles with at least one author based in Africa can now be submitted to the platform and will no longer require funding from a partnering research funder. This expansion aims to increase publication efficiency and improve the experience of African authors, while promoting the rapid sharing and discovery of high-quality research.
Simon Fraser University is pioneering a university-wide open scholarship framework, guided by six principles, to advance research, innovation and sustainable development. This initiative aligns with the university's commitment to the United Nations Sustainable Development Goals and aims to increase the visibility, dissemination and rea...
The SpongeBoost project visualizes sponge functions in wetlands using a comic book, simplifying complex concepts for experts and non-experts. The first edition of the comic book is available online, promoting nature-based solutions to enhance landscape resilience.
The MIT Press has funded the open publication of 320 books through its Direct to Open framework, which shifts from market-based purchase models to collaborative library-supported open access. This approach has shown significant usage and citation increases for Humanities and STEAM books, with a notable impact on global readership.
A study using NHANES data found that inflammation, rather than diet and exercise, has the strongest association with telomere shortening. Managing chronic inflammation may be key to preserving telomere length and promoting healthy aging.