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Controlling respiratory syncytial virus: real life data from Luxembourg

Early data from Luxembourg's national immunisation campaign against severe respiratory syncytial virus (RSV) in 2023 showed a decline in hospitalisations, especially among infants under six months old. The authors attributed this to the administration of a monoclonal antibody, nirsevimab, shortly after birth. Additionally, the mean age...

SourceEuropean Centre for Disease Prevention and Control (ECDC)·JournalEurosurveillance·TypeData/statistical analysis·DateJan 29, 2024

Breakthrough technology offers promising treatment for ischemic retinopathy

Researchers develop technology that alleviates retinal pathologies by targeting mitochondrial chaperone TRAP1, which is implicated in the breakdown of blood-retinal barrier and pathological neovascularization. This treatment approach holds great promise for revolutionizing the treatment landscape for ischemic retinopathy.

Infants born to COVID-infected mothers have triple the risk of developing respiratory distress

A new study finds that infants born full-term to mothers infected with COVID-19 during pregnancy are three times more likely to develop respiratory distress compared to uninfected infants. Vaccination prior to infection was found to be protective, reducing the risk by half.

SourceUniversity of California - Los Angeles Health Sciences·JournalNature Communications·TypeObservational study·DateJan 24, 2024

Higher infant mortality rates associated with restrictive abortion laws

A new study found that states with restrictive abortion laws had a 16% increased infant mortality rate compared to those with more comprehensive reproductive healthcare. Demographic factors such as low education attainment and inadequate prenatal care also contributed to elevated IMR.

SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateJan 17, 2024

Study on extremely preterm infants provides important healthcare knowledge

A large clinical study led by Linköping University found no difference in the risk of severe complications between breast milk-based and cow's milk-based enrichment for extremely preterm infants. The study included 228 infants and found that both groups had a similar incidence of necrotising enterocolitis, sepsis, and death.

SourceLinköping University·JournalEClinicalMedicine·TypeRandomized controlled/clinical trial·DateJan 2, 2024

Common heart medication digoxin shows promise in enhancing survival after surgery for infants with certain heart defects

A recent study published in the Journal of the American Heart Association found that digoxin treatment significantly reduced mortality and the need for a transplant among infants undergoing a hybrid procedure for single-ventricle physiology. The researchers analyzed data from 259 infants who received digoxin during their interstage per...

SourceMedical University of South Carolina·JournalJournal of the American Heart Association·TypeData/statistical analysis·DateDec 26, 2023

City living can pose developmental risks

A new study highlights the wide range of urban exposures during early childhood that can influence growth and development, including air and noise pollution, overcrowding, and limited green space. The first 2000 days of life are a critical period for physical, cognitive, social, and emotional health outcomes.

SourceUniversity of Technology Sydney·JournalPublic Health Research & Practice·TypeLiterature review·DateDec 20, 2023

Prenatal exposure to GLP-1 receptor agonists and other second-line antidiabetics may not pose greater risk to infants than insulin

A new study found no increased risk of major congenital malformations in infants exposed to second-line non-insulin antidiabetic medications during pregnancy compared to those treated with insulin. The study examined over 3.5 million pregnancies and provided reassurance on the safety of these medications for fetuses.

SourceHarvard T.H. Chan School of Public Health·JournalJAMA Internal Medicine·TypeObservational study·DateDec 11, 2023

Milestones in Europe: First results in using new tools to tackle respiratory syncytial virus

The European Union has approved vaccines for pregnant women and monoclonal antibodies to prevent respiratory syncytial virus (RSV) among young children. New sequencing tools have also been developed to track the genetic diversity of RSV and inform vaccine effectiveness and treatment strategies.

SourceEuropean Centre for Disease Prevention and Control (ECDC)·JournalEurosurveillance·TypeCommentary/editorial·DateDec 8, 2023

Children born moderately early are at an increased risk of developmental disorders, according to new research

A new study found that children born moderately early are at an increased risk of developmental disorders, including language delay, cognitive impairment, ADHD, and cerebral palsy. The study analyzed data from over 8 million children and identified a small but significant increase in risk for most developmental disorders.

SourceUniversity of York·JournalPEDIATRICS·TypeMeta-analysis·DateDec 7, 2023

Pregnant women are missing vital nutrients needed for them and their babies – and situation could worsen with plant-based foods

A study published in PLOS Medicine found that 90% of pregnant women in high-income countries lack key vitamins necessary for healthy pregnancies and fetal development. The situation is expected to worsen as more people adopt plant-based diets, leading to increased risk of nutrient deficiencies.

SourceUniversity of Southampton·JournalPLOS Medicine·TypeRandomized controlled/clinical trial·DateDec 5, 2023

Pregnant women are missing vital nutrients crucial for them and their babies

A recent study found that nearly all pregnant women have low levels of essential vitamins and minerals, with some developing deficiencies in late pregnancy. Supplementing with over-the-counter multivitamins significantly reduced nutrient deficiencies before and during pregnancy.

SourceNational University of Singapore, Yong Loo Lin School of Medicine·JournalPLOS Medicine·TypeRandomized controlled/clinical trial·DateDec 5, 2023

Infants are not startled by visual illusions

A recent study reveals that infants aged six months and older can perceive misbinding, a type of visual illusion where features are mistakenly integrated. In contrast, infants under six months do not exhibit this phenomenon, indicating they may perceive the external world more accurately than adults.

SourceChuo University·JournalProceedings of the Royal Society B Biological Sciences·TypeObservational study·DateDec 4, 2023

Cannabis use in pregnancy may raise infant health risks

A large Kaiser Permanente study found a connection between prenatal cannabis use and increased risk of low birthweight and neonatal intensive care unit (NICU) admission. The study analyzed over 360,000 mothers and infants and found a dose-response relationship between cannabis use and infant health risks.

SourceKaiser Permanente·JournalAmerican Journal of Obstetrics and Gynecology·DateNov 27, 2023

AI predicts developmental paths in premature babies

Researchers at UMC Utrecht developed an AI model to predict long-term outcomes in extremely premature babies, identifying those at risk of intellectual disability. The model analyzed brain activity data with 80% accuracy, offering valuable information for healthcare providers and parents about expected developmental journeys.

SourceUniversity Medical Center Utrecht·JournalThe Lancet·TypeComputational simulation/modeling·DateNov 24, 2023

Research shows infants exposed to certain biologics during pregnancy can safely receive rotavirus vaccine

A Canadian study found that infants exposed to biologic agents during pregnancy have normal immune development and can safely receive the rotavirus vaccine. The study, involving 191 infants across six sites in Canada, aimed to change vaccination guidelines to protect more babies from severe illness.

SourceUniversity of Calgary·JournalThe Lancet Child & Adolescent Health·TypeObservational study·DateNov 23, 2023

How AI could help optimize nutrient consistency in donated human breast milk

Researchers developed an AI model to optimize the macronutrient content of pooled human donor milk recipes, decreasing production time by 60%. The model improved protein and fat levels in milk bank products without compromising bacterial safety, benefiting preterm and sick babies.

SourceUniversity of Toronto Faculty of Applied Science & Engineering·JournalManufacturing & Service Operations Management·DateNov 21, 2023

The Lancet: Deferred clamping of umbilical cord reduces risk of death in premature babies by at least a third, suggest two studies with the most comprehensive analysis to date

Two systematic reviews and meta-analyses found that delaying umbilical cord clamping by at least two minutes can reduce the risk of death in premature babies. The studies included over 10,000 babies from 60 studies and showed a significant reduction in mortality rates for deferred clamping compared to immediate clamping.

SourceThe Lancet·JournalThe Lancet·TypeMeta-analysis·DateNov 14, 2023

Worcester Polytechnic Institute researcher leads project to develop oxygen sensor for premature infants of color

A team led by WPI researcher Ulkuhan Guler has received NIH funding to develop a wearable sensor for premature infants that can mitigate skin-color bias in oxygen level measurements. The four-year project aims to create a convenient and affordable sensor that will enable infants at risk of lung disease to leave hospitals sooner.

Umbilical cord milking appears to be safe in preterm infants born after 28 weeks

A recent study suggests that umbilical cord milking is a safe procedure for preterm infants born after 28 weeks, reducing delay and risk of bleeding. The technique involves gently squeezing the cord to push blood into the newborn's abdomen, allowing for faster response times for infants in need of respiratory support.

Umbilical venous catheterization and bloodstream infection among preterm infants

A national-level study found that the median UVC dwell time was 7 days, and CLABSI incidence did not differ significantly between 0-7 days and 7-15 days. The study also highlighted high rates of antibiotic exposure without reduction in CLABSI rates, emphasizing the need for nuanced approaches to antibiotic administration.

SourceCactus Communications·JournalPediatric Investigation·TypeObservational study·DateOct 31, 2023