Marco Demaria named editor-in-chief of Aging (Aging-US)
Dr. Marco Demaria joins Aging-US as Editor-in-Chief with expertise in cellular senescence and aging research. He aims to develop new therapeutic approaches to mitigate age-related diseases.
Publishing Industry
Articles tagged with Publishing Industry
Chung-Ang University researchers develop self-powered tactile sensors for robotics and wearables
Chung-Ang University researchers have developed self-powered tactile sensors for robotics and wearables by introducing novel manufacturing strategies for piezoelectric and triboelectric sensors. These advancements aim to create high-performance sensors capable of multi-modal sensing and real-time interaction.
SourceChung Ang University·JournalInternational Journal of Extreme Manufacturing·TypeLiterature review·DateJan 2, 2025
Researchers have uncovered how foreign DNA can evade bacterial defense systems and neutralize them
A new study reveals that anti-defense genes near the DNA entry point enable plasmids to overcome CRISPR system, promoting genetic transfer between bacteria. This discovery could pave the way for developing tools to address antibiotic resistance and genetic manipulation methods.
'Capture the oxygen!' The key to extending next-generation lithium-ion battery life
A POSTECH research team developed a groundbreaking strategy to enhance LLO material durability, extending battery lifespan by up to 84.3% after 700 cycles. The breakthrough addresses capacity fading and voltage decay issues.
SourcePohang University of Science & Technology (POSTECH)·JournalEnergy & Environmental Science·DateDec 24, 2024
The ancient copper industry in King Solomon's mines did not pollute the environment
A new study from Tel Aviv University finds minimal environmental pollution resulting from ancient copper production in King Solomon's Mines, with pollution levels confined to smelting furnaces. Researchers also contradict previous claims of widespread industrial pollution, citing low levels of lead and other metals in soil samples.
Programming cells: Revolutionizing genetic circuits with cutting-edge RNA tools
The team developed a Synthetic Translational Coupling Element (SynTCE) that enhances the precision and integration density of genetic circuits in synthetic biology. This allows for more efficient gene circuit integration, minimizing interference between biological parts and enabling precise control over multiple genes.
SourcePohang University of Science & Technology (POSTECH)·JournalNucleic Acids Research·DateDec 20, 2024
New study highlights ethical challenges in conducting cannabis research in Canada
A recent study published in Social Science & Medicine reveals the complexities of conducting cannabis research in Canada, where researchers face structural barriers and concerns about scientific integrity. The study suggests key solutions to increase public funding, enhance transparency, and promote independence in research.
SourceCentre for Addiction and Mental Health·JournalSocial Science & Medicine·TypeSurvey·DateDec 19, 2024
Sexual dimorphism in thermotherapy responses in APP/PS1 mice
A new study found that heat therapy positively modulates multiple physiological parameters in APP/PS1 mice, with improved memory in males and worsening effects on females. This highlights the importance of personalized treatments based on sex-specific responses to therapy.
How the dirt under our feet could affect human health
Researchers found that soil contains antibiotic resistance genes that can be transmitted to humans, making it a pressing public health threat. The study reveals how these genes spread through the environment and highlights the importance of understanding soil ecosystems to control antibiotic resistance.
WVU research finds CEOs innovate — or don’t — based on compensation packages and input from analysts
CEOs innovate based on stock recommendations and analyst feedback, which can foster explorative activities like R&D. However, many sacrifice long-term sustainability for immediate returns, incentivized by their compensation packages.
Breakthroughs in cell-penetrating monoclonal antibody therapies
Researchers have developed a new generation of cell-penetrating antibodies that can target cancer cells and deliver therapeutic molecules directly into tumor cells. The 3E10 antibody shows great promise for treating cancers with defective DNA repair pathways.
How job ads shape gender and racial segregation in the UK workforce – new study
A new study by Lancaster University reveals that language in job ads can unintentionally reinforce or disrupt labour force gender/racial composition. Workforces with more women tend to use family-friendly policies in ads, while racial minority workers' ads lack impact, the research shows.
Accelerated aging in young sickle cell patients linked to elevated T-cell p16INK4a
Researchers found significantly higher levels of p16INK4a in young people with sickle cell disease, indicating accelerated cellular aging. This discovery may lead to new treatments targeting cell aging and improved quality of life for SCD patients.
PLOS receives $3.3 million grant to support Open Access publishing & business model transformation
PLOS has been awarded a $3.3 million grant from the Bill & Melinda Gates Foundation to transition towards APC-free publishing and promote open access options for authors without funding. The grant will also support improvements in funding metadata capture and peer review transparency.
Chungnam National University researchers uncover breakthrough in copper-zinc electrodes for electrochemical CO₂ reduction
Researchers at Chungnam National University have developed copper-zinc electrodes that can stabilize over time through recycling, preserving their catalytic effectiveness and selectivity for valuable hydrocarbons. This innovation has significant implications for the conversion of CO₂ into sustainable fuels or chemicals.
SourceChungnam National University Evaluation Team·JournalApplied Surface Science·TypeExperimental study·DateDec 10, 2024
Prostaglandin E2’s role in senescence and neoplastic escape in human keratinocytes
Researchers discovered that Prostaglandin E2 drives skin cells to age and enables some of these cells to become pre-cancerous, leading to increased cancer risk. The study found that blocking PGE2 reduced the chances of aged cells becoming precancerous.
Smartphones can alert us to wildfires and extreme weather conditions
A new study from Tel Aviv University uses smartphone data to predict wildfire risk, overcoming individual device errors by averaging large amounts of public data. The method provides valuable insights into wildfire evaluation, especially in remote areas lacking traditional weather stations.
B7-H4 as a therapeutic target in adenoid cystic carcinoma
Researchers have found that B7-H4 helps ACC tumors evade the immune system, leading to poor survival outcomes. A new drug targeting B7-H4 showed promising results in shrinking tumors in aggressive cases.
Effects of megakaryocyte conditioned media on endothelial cell angiogenesis
Researchers found that megakaryocyte conditioned media from younger mice was more effective at promoting blood vessel growth and improving healing. The study provides a potential approach for developing new therapies to speed up fracture recovery in older individuals, reducing pain and improving mobility.
Mesenchymal stem cells in cancer immunotherapy: Promises and challenges
Mesenchymal stem cells (MSCs) show promise in delivering treatments directly to cancer cells and boosting the immune system's fight against cancer. However, ongoing research highlights challenges related to MSC behavior, including variability in their effects and potential to create conditions that support tumor growth.
Analysis of ground motions recorded on October 7th reveals the seismic signature of Hamas forces en route to their terrorist attack
Researchers analyzed seismic data from southern Israel and found weak ground motions caused by Hamas forces' unusual vehicle movement. This breakthrough highlights the potential of using seismic data to provide early warnings for future terrorist activities.
Ban medical research with links to the fossil fuel industry, say experts
An investigation by The BMJ found over 180 medical articles funded by the fossil fuel industry, with ties to top journals including The BMJ and The Lancet. Experts demand stronger action against the industry's influence on research, citing similarities with tobacco companies in harm caused and tactics used.
Persistence landscapes: A path to unbiased radiological interpretation
This editorial introduces persistence landscapes as a mathematical method to identify and correct biases in medical imaging. Persistence landscapes offer a way to reduce random noise while preserving important details, making it easier for clinicians to focus on meaningful image parts.
The Plant Cell welcomes Brian Gregory as first Deputy Editor
Brian Gregory joins The Plant Cell editorial team with expertise in molecular biology, epigenetics, and RNA silencing. He will handle papers with conflicts of interest, develop focus issues, and oversee post-publication corrections.
Nucleoporin93: A silent protector in vascular health
Research highlights Nup93's critical role in endothelial cell function and vascular health, with promising findings for new treatments to slow down aging. Low Nup93 levels are associated with inflammation and cellular aging, while restoring its levels can reverse harmful effects.
Insilico Medicine’s CEO named Highly Cited Researchers of 2024
Alex Zhavoronkov, Insilico Medicine's founder and CEO, was named Highly Cited Researchers of 2024. He has published over 40 peer-reviewed research papers, with a total H-index of 64, and led the development of Insilico's lead drug pipeline, ISM001-055.
Improving our appearance makes us better contributors to society
A Tel Aviv University study finds that individuals who enhance their appearance are more likely to exhibit prosocial behavior, including donating to charity. The research suggests that feeling attractive can motivate people to engage in good deeds, with a significant impact on social consciousness.
Persistence barcodes: Reducing bias in radiological analysis
Researchers introduce persistence barcodes, a tool that reduces diagnostic bias and uncovers subtle details in medical images. The method preserves key structural details, enabling clearer insights into the data.
Phenotypic and epigenetic clocks for aging and mortality
This systematic review analyzes 33 biological clocks used for aging and mortality quantification, categorizing them into epigenetic and phenotypic clocks. Epigenetic clocks demonstrate precision in estimating chronological age through DNA methylation, while phenotypic clocks predict mortality using easily measurable clinical variables.
Brain aging and Alzheimer's: Insights from non-human primates
A new review highlights the differences in brain aging and Alzheimer's disease between humans and non-human primates, revealing that primate brains are more resistant to aging-related damage. The study suggests that tau tangles play a critical role in Alzheimer's progression, challenging the amyloid cascade hypothesis.
Editorial interview in IEEE Journal of Selected Topics in Quantum Electronics on the future of optical modulators and integrated photonics
Industry and academic experts discuss the potential of new materials, configurations, and integration technologies to overcome bandwidth limitations and operational robustness issues in silicon photonic modulators. These advancements are expected to impact emerging applications such as data centers, AI, quantum information processing, ...
SourceInstitute of Electrical and Electronics Engineers·JournalIEEE Journal of Selected Topics in Quantum Electronics·TypeCommentary/editorial·DateNov 18, 2024
Reducing bias in radiology with topological data analysis
A new approach using topological data analysis (TDA) enhances the reliability and reduces bias in AI systems used for medical diagnosis in radiology. TDA captures intricate features and provides a holistic view of medical images, leading to more accurate diagnoses and equitable patient care.
Targeting carbohydrate metabolism in colorectal cancer: Synergy of therapies
Researchers explore potential synergies between chemotherapy, cannabinoids, and intermittent serum starvation in treating colorectal cancer. Combining these therapies could create a strong synergy by depriving cancer cells of glucose, making them more susceptible to treatment.
Maarja Öpik to take up the position of New Phytologist Editor-in-Chief from January 2025
Professor Maarja Öpik will lead the journal's international board of Editors, focusing on all aspects of plant biology. She aims to maintain an active and engaging scientific community, publishing inspiring papers that contribute to strengthening New Phytologist.
Updated first aid guidelines enhance care for opioid overdose, bleeding, other emergencies
The 2024 Guidelines for First Aid provide critical updates on recognizing and responding to mild, moderate, and life-threatening emergencies. The guidelines offer enhanced guidance on managing opioid overdoses, bleeding, and other conditions, as well as improved recommendations for emergency care involving children.
EphA2 signaling in eye lens aging: wild-type, knockout, and aging mice
Researchers from Indiana University have uncovered how the EphA2 protein receptor contributes to cataract formation. The study found that canonical ligand-dependent EphA2 signaling remains stable in aging lens tissue, while non-canonical signaling increases with age, affecting lens fiber cell maturation.
Validating an electronic frailty index in a national health system
A new study introduces the Meuhedet Electronic Frailty Index (MEFI) to assess frailty in older people and identify those at risk for serious health outcomes. The index classifies individuals as 'fit,' 'mildly frail,' or 'severely frail' and has been shown to predict mortality and hospitalization with high accuracy.
Taylor & Francis announces Open Access Collective Funding Pilot
The Collective Pathway to Open Publishing (CPOP) pilot program aims to support Humanities and Social Sciences (HSS) journals by combining OA agreements with 'read' income. CPOP will make all articles in participating journals open access if thresholds are met, expanding their international reach and impact.
Extracellular matrix and tumor-immune interactions: challenges & opportunities
The review explores the impact of extracellular matrix (ECM) geometry on immune cell behavior and treatment efficacy. Specific ECM configurations, known as Tumor-Associated Collagen Signatures (TACS), create physical barriers that limit immune cell access to tumors.
Navigating bias in AI-driven cancer detection
AI models trained on limited data may misdiagnose certain populations, particularly those in underserved communities. Researchers propose six key strategies to develop fair AI models, including using diverse datasets and transparent decision-making processes.
INSEAD retains 3rd position in global research impact ranking
INSEAD ranks third globally among international business schools and holds the top position among European institutions. The school's commitment to research excellence and the case method has been recognized with the #3 position in The Case Centre Impact Index 2024.
Precision medicine in SCLC: DLL3, ASC1, TTF-1, and Ki-67 expression
Researchers analyzed tumor samples from 64 SCLC patients, identifying promising results for biomarkers DLL3 and TTF-1. These biomarkers showed potential as targets for therapies like Tarlatamab and improved survival rates in patients with TTF-1-positive tumors.
Gendered bilingualism in post-colonial Korea
Research finds that Korean newspapers often focused on women learning Japanese for work and social purposes, not just reading novels. The ability to speak Japanese gave women new opportunities and challenged traditional roles in Korea.
Werner syndrome RECQ helicase and heterochromatin maintenance in human cells
Researchers discovered Werner syndrome gene WRN plays a crucial role in maintaining constitutive heterochromatin structure, essential for DNA stability. Loss of WRN function disrupts protein interactions, potentially accelerating aging due to cellular disorganization.
Taylor & Francis joins DAISY Consortium’s Inclusive Publishing Partner program
Taylor & Francis joins DAISY Consortium’s Inclusive Publishing Partner program to advance accessibility in publishing. The company is committed to producing content accessible to all, regardless of reading requirements.
Immunotherapy success in KRAS G12C adenosquamous pancreatic cancer
Researchers document remarkable response to pembrolizumab in patient with metastatic adenosquamous pancreatic cancer (ASCP) and KRAS G12C mutation. The study highlights potential shift in treatment of ASCP, a rare form of pancreatic cancer traditionally underserved by current therapies.
Longevity biotechnology: AI, biomarkers, geroscience & applications for healthy aging
Researchers synthesizing AI with biomarker analysis aim to detect early signs of aging and enable targeted interventions to delay disease. This approach has the potential to slow, prevent or reverse certain effects of aging.
Tumor dormancy initiated by lymphovascular embolus
Researchers discovered that tumor dormancy in breast cancer can be triggered by specific signaling changes within small cell clusters, called tumor emboli. Key mechanisms include reduced activity of mTOR and structural shifts in E-cadherin, which are regulated by the PI3K pathway.
Improving deer health one test at a time
A recent study by Mizzou researchers found that infections are a significant problem for white-tailed deer on Missouri farms. The study identified the three most common types of bacteria causing pneumonia in farmed deer, providing actionable data for veterinarians and farmers to make informed decisions.
SourceUniversity of Missouri-Columbia·JournalJournal of Veterinary Diagnostic Investigation·TypeExperimental study·DateOct 30, 2024
Trauma, homelessness afflict gender affirming care patients at higher rates
A Colorado School of Public Health study reveals that gender affirming care patients experience disproportionately high levels of trauma, homelessness, and housing insecurity. Commercial insurance covers most treatments, but access to care varies by region.
SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of General Internal Medicine·DateOct 29, 2024
Cardiovascular risk biomarkers in inflammaging
Researchers propose a comprehensive biomarker-based approach to assess cardiovascular risk by combining markers of chronic inflammation with cardiac health indicators. This approach reveals the significant impact of aging-related inflammation, or 'inflammaging,' on heart health and opens new avenues for targeted interventions.
Complete response to encorafenib + binimetinib in BRAF V600E-mutant tumor
A remarkable clinical and metabolic response is reported in a metastatic BRAF V600E-mutated glomangiosarcoma treated with encorafenib and binimetinib. The combination of BRAF and MEK inhibitors achieves a long-lasting complete morpho-metabolic response in the patient.
New model to study macrophage aging mechanisms
Researchers developed an in vitro model of murine peritoneal macrophage aging to study molecular mechanisms and develop innovative strategies. Chronic treatment with CB3 completely prevented the increase of p21CIP1 and maintained proliferative activity in day 14 macrophages.
How blood cancer cells rewire to evade drug treatment
Researchers found that blood cancer cells rewired their gene regulatory networks to evade drug treatment in Acute Myeloid Leukemia (AML), disrupting normal differentiation and growth. The study identified key findings, including changes in open chromatin regions and the loss of binding of RUNX1 and AP-1 transcription factors.
Steenkamp to edit the Journal of Marketing
Jan-Benedict E.M. Steenkamp, a renowned marketing expert, has been selected as the next Editor-in-Chief of the Journal of Marketing, effective July 1, 2025. With his extensive research experience and leadership skills, Steenkamp aims to expand the journal's tradition of high-quality research.
Senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in mice
Researchers used a mouse model to assess the impact of senolytic agents dasatinib and quercetin on pelvic organ prolapse. The study found that D+Q injections did not result in significant differences in prolapse development but reduced cellular senescence markers.
Next-gen cell-penetrating antibodies for tumor targeting and RAD51 inhibition
Researchers humanize the lupus-derived autoantibody 3E10, preserving its therapeutic efficacy, to create novel cell-penetrating antibodies targeting tumors and RAD51. Humanized variants exhibit faster cell uptake and superior in vivo tumor targeting.
Fibroblast growth factor 21 and survival in the elderly: Polsenior2 study results
A new study found that fibroblast growth factor 21 (FGF21) is an independent predictor of all-cause mortality in older adults. The Polsenior2 study revealed that middle and high FGF21 levels were associated with increased mortality risk, particularly when adjusted for age, co-morbidities, and blood parameters.
Smaller, more specific academic journals have more sway over policy
A new study by Duke University researchers reveals that smaller, specialized science publications have a disproportionate impact on conservation efforts. The team found that journals focused on specific regions or organisms were often cited more frequently by federal agencies than high-impact journals.
Molecular chaperones: Guardians of tumor suppressor stability
Research highlights molecular chaperones' role in maintaining tumor suppressor stability and functional integrity. This understanding is crucial for developing targeted therapies for multiple cancers.