Researchers suggest that hematopoietic stem and progenitor cells in the AML niche may retain an inflammatory memory, potentially leading to long-term functional consequences. This finding has significant implications for understanding the biology of acute myeloid leukemia (AML) and developing new cancer therapies.
Research explores relationship between cardiac metabolism dysfunction and heart failure in the elderly, revealing potential therapeutic targets for improved cardiac outcomes. The study highlights the critical role of Pdk4 and MIF in cardiac metabolism, suggesting innovative treatments to manage interconnected cardiovascular conditions.
Researchers identify key genes involved in osteoblast differentiation, finding positive correlations between WNT10B and these genes, and inverse correlations with WNT5B. The study hypothesizes that the use of WNT activators or inhibitors depends on whether canonical or non-canonical pathways are activated.
Researchers analyzed young and aged dermal fibroblasts, finding a significant decrease in protein secretion with age. The study also revealed an increase of over 60% in cytoplasmic protein accumulation, highlighting the cytoskeleton's crucial role in skin aging.
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A new vaccine created by Mizzou researchers protects cattle from bovine anaplasmosis, a devastating tick-borne disease causing hundreds of millions of dollars in economic losses. The vaccine has been proven to give immunized cattle protection for at least a month and is being discussed with industry partners for future distribution.
A recent study by University of Missouri researchers found that giving nurses massages during their shifts can reduce physical aches and pains while improving mental rejuvenation. The study's lead researcher aims to create a healthier work environment where nurses are excited to remain in the profession long-term.
A recent study published in PLOS Biology investigated the effectiveness of eLife's standard wording for evaluating scientific article importance. The research, conducted online, revealed that participants' implied rankings often diverged from the intended meaning.
Researchers have identified HLA-E as a critical negative regulator of NK cell interactions with cancer cells. Disrupting NKG2A:HLA-E interactions may stimulate both NK cell and cytotoxic T cell effector functions against cancer, offering a promising anti-cancer strategy.
Researchers discuss diverse BRAF alterations found in human cancers and strategies to inhibit them. Class I BRAF inhibitors represent a landmark achievement in precision oncology, with FDA-approved dabrafenib/trametinib for metastatic BRAF p.V600E-mutant solid tumors.
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new study found that mTORC1 activity correlates with classical biometrics, such as height and macrocephaly, as well as specific neuropsychiatric diseases like anxiety and autism. The research suggests that human variability of mTORC1 gain of function may predict medication response.
Researchers are developing a framework to combine AI and human intelligence in process safety systems, aiming to enhance safety and efficiency. The study identifies challenges and benefits of using Intelligence Augmentation (IA) and proposes strategies for effective implementation to minimize risks.
Researchers isolated three bacterial strains that produce amylase enzymes from sugar factory waste, showing great potential for production. The optimal conditions for amylase production were found to be 37°C and pH 7.0, leading to increased enzyme activity.
The article reviews recent advances in applying artificial intelligence to oncology, showcasing promising improvements in cancer care. The authors emphasize the need for interdisciplinary collaboration, rigorous validation, and ethical principles to harness AI's potential.
Research by Lancaster University found that people in higher social grades, including corporate world and education sectors, are adopting each other's speech patterns to be more inclusive. This 'resonance' has increased over the past 20 years, particularly among those with high social status.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers at Tel Aviv University developed a method to grow ultra-long and narrow graphene nanoribbons with semiconducting properties, opening doors for technological applications in advanced switching devices and spintronic systems. The study's success demonstrates a breakthrough in carbon-based nanomaterials.
The Academic Payvider model enhances value-based care by fostering improved coordination, reduced insurance hassles, and increased staff attention. This joint approach between payers and providers aims to drive complex care down through innovative reimbursement structures.
A WVU study found that treating work like a game improves workers' productivity and engagement, but also increases stress levels. Gamification can boost completion times for repetitive tasks, but may push employees past their tolerance threshold, leading to frustration and physical demands.
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A new multitasking substance has been identified to prevent and treat both flu and COVID-19 infections concurrently. The long-acting recombinant cytokine protein rhIL-7-hyFc demonstrated therapeutic and preventive effects against various respiratory diseases, including COVID-19, influenza virus, and respiratory syncytial virus.
The MIT Press is accepting applications for its shift+OPEN initiative, which provides funding and support to convert subscription-based journals to diamond open access. Selected journals will receive three-year funding, professional publishing services, and sustainable funding model development support.
A new study from the University of Kansas found that copy editors experienced high job satisfaction despite the COVID-19 pandemic, with many reporting a passion for their work. The researchers also found that the pandemic did not significantly affect burnout or role overload among participants.
Several key public health occupations, including disease intervention specialist and program manager, do not have valid SOC matches, creating challenges in researching the workforce. The study's findings highlight the need for standardization to characterize the public health workforce linked to SOC codes.
Letters in Applied Microbiology invites submissions on Pseudomonas biotechnology, covering applied biotechnology and metabolic engineering, as well as novel genetic tools. Early-career researchers are encouraged to share their work, fostering collaboration and inspiring future innovations.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
The C-Path Neuroscience Annual Workshop brought together stakeholders to chart a transformative course for neurology research and drug development, focusing on chronic progressive diseases such as Alzheimer's and Parkinson's. Key highlights included recommendations for innovative therapies and tools to address complex disorders.
Researchers from the UMA developed an open-source platform called Open Twins to create more accessible and versatile digital twins. This platform enables the simulation of real-world assets based on virtual replicas, predicting future behaviors and detecting anomalies, leading to more efficient companies that make data-driven decisions.
Research from TU Dortmund University and RWTH Aachen University suggests that marketing academia has focused on identifying new phenomena, but neglected building 'big-picture' frameworks and theories. This limits the field's ability to provide answers to complex marketing problems.
Researchers propose analysis protocol to evaluate feasibility of silicon-containing batteries with reduced particle size and uniform dispersion. The study finds promising results from innovative synthesis technology and initial efficiencies exceeding 90% with improved lifespan characteristics.
NUTRITION 2024 will convene in Chicago to explore the latest nutrition research and share findings on diet and disease, artificial intelligence, and precision nutrition. The event promises to be a knowledge-packed experience with scientific symposia, educational sessions, and networking opportunities.
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
The MIT Press is expanding its shift+OPEN initiative with a $275,000 NSF grant to flip two high-impact subscription-based journals to diamond OA. The program aims to accelerate STEM and HSS research by providing barrier-free access to scholarly works.
The UNIST team successfully fabricated high-quality Te thin films without heat treatment at low temperatures, achieving perfect atom arrangement. The developed process enables precise thickness control and uniform deposition on wafer-scale, suitable for various electronic devices.
Dr Saskia Limbach receives ERC Starting Grant to investigate the effects of the printing press on widows' rights and agency. The project 'WidowsPrint' aims to reconstruct the professional networks of women book printers and analyse their economic contributions in 16th-17th century Germany.
Research has clarified how starch granules form in wheat seeds, unlocking diverse potential benefits for various industries. The discovery of the enzyme PHS1 crucial for B-type granule initiation offers opportunities to create variations in starch for different food and industrial applications.
Impact Journals will participate as an exhibitor at the AACR Annual Meeting 2023, showcasing Aging's growth in impact factor to 5.955. The meeting theme focuses on Advancing the Frontiers of Cancer Science and Medicine.
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
The EU project CRAFT-OA aims to strengthen institutional publishing using Diamond Open Access model across Europe. The project will enable local platforms and service providers to expand their content services with the aim of networking them with other information systems in science.
Researchers found that lncRNA MVIH is overexpressed in cervical cancer tumors and associated with younger age, lymph node metastasis, tumor invasion depth, and squamous cell type. This suggests its potential as a diagnostic biomarker for cervical cancer.
A new case study explores the early years of BioOne and SPIE's nonprofit platform partnership, highlighting its potential to reduce costs and enhance strategic development. The authors share key lessons learned, including the importance of regular communication and reciprocal service-level agreements.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
The MIT Press and American Academy of Arts & Sciences have made Dædalus, the journal of the American Academy, openly available. This move has led to an increase in online readership and downloads, with over 450,000 essay downloads between 2020 and 2021.
A new study suggests that prelamin A, a precursor of lamin A, accumulates with age and may drive normal aging. Researchers propose this protein as a target for intervention strategies to extend healthspan and lifespan.
A study using mRNA and miRNA expression profiles identified molecular signatures that can differentiate muscle invasive bladder cancer patients who respond to neoadjuvant chemotherapy from those who do not. The research found distinct gene pathways and subtypes associated with response, which may lead to more effective treatment delivery.
Researchers found that overexpressing matriptase reduced myeloma cell proliferation and inhibited migration. Matriptase also blocked Src kinase activation, supporting its potential as a tumor suppressor in multiple myeloma. The study provides new insights into the role of matriptase in hematological malignancies.
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
eLife is ending its practice of making accept/reject decisions following peer review, instead publishing every paper it reviews as a Reviewed Preprint. This new model restores control to authors, promoting the assessment of scientists based on their research output rather than publication venue.
The FDA's warning letters issued in 2020 and 2021 revealed that the regulator is failing to target leading tobacco companies and products most popular among young people. Over 90% of warnings were sent to small online retailers, while flavoured refillable e-cigarette liquids accounted for over 90% of the products cited.
A 50-year analysis of scholarly research papers found an overall increase in productivity, with environmental sciences and engineering leading growth. However, a worldwide gender gap persists, widening in some countries and narrowing in others.
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
This volume of Oncotarget features groundbreaking research on various cancers, including breast, lung, colorectal, and neuroblastoma, as well as novel drug targets for bladder cancer. The studies also delve into the role of BRCA in breast and colorectal cancers.
Research published in PLOS ONE reveals women make up approximately a quarter of first authors in The Lancet, JAMA, and NEJM. Despite some progress, no notable improvement was observed between 2002 and 2019, highlighting the persistence of a glass ceiling in academic medicine.
Predatory academic practices are rising globally, with over 80% of researchers indicating they have used problematic outlets. The IAP report recommends training, responsible publishing policies, and transparency in peer-review systems to combat these practices.
A study found that LGBTQA scientists who hide their identities publish significantly fewer peer-reviewed articles than those who disclose. This could indicate a performance disadvantage due to non-disclosure
A qualitative study found that industry arguments against alcohol health warning labels were cited by World Trade Organization representatives, despite not being explicitly stated as industry demands. This highlights the need for greater transparency and curbing the alcohol industry's influence on global policy implementation.
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A recent study highlights the negative effects of misinformation on stem cell therapies for COVID-19, including exaggerated claims and unregulated sales. The researchers advocate for increased enforcement of laws and regulations to protect patients and promote responsible science communication.
Pharmaceutical companies in the Open Pharma collaboration recommend developing plain language summaries of peer-reviewed medical research articles. The summaries should be understandable, unbiased, non-promotional, and easily accessible. This move aims to make medical publishing more open and inclusive for all audiences.
The MIT Press has partnered with Jisc to provide central licensing and invoicing for Direct to Open, a framework that moves books from a market-based model to a library-supported open access model. Libraries committing to D2O before September 30 will earn exclusive benefits, including term access to an archive of gated titles.
Researchers found that adding a new outlet can modestly benefit existing locations in markets with few same-brand outlets, leading to increased revenues and profits. The study's findings suggest prioritizing markets with few same-brand outlets, newer brands, cross-brands, and online travel agency sales channels for expansion.
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new study finds that electronic waste generated by Americans has been declining since 2015, mainly due to the decrease of bulky CRT displays. This decline poses challenges for e-waste recycling regulations and the recovery of critical elements like cobalt and indium.
Dr. Juan Madera has been recognized as a Fellow of the Society for Industrial and Organizational Psychology (SIOP) for his outstanding research on diversity management in the hospitality industry. His work has had a significant impact on job attitudes, discrimination, and sexual harassment in organizational settings.
An expert panel recommends companies undergo third-party evaluations to certify probiotic quality and label accuracy. They suggest publicly available quality standards and methods to provide consumers with certainty about what's in their probiotic product.
A new study by North Carolina State University reveals that wineries with more sustainable practices experience better financial performance when they feel competitive pressure. Conversely, those without significant competitive pressure are more likely to adopt new sustainability measures.
A study by Queensland University of Technology researchers found that tourists trust destinations like London based on its vibrancy, contemporary, competence, sophistication and sincerity. The results showed that when a destination is perceived as competent, it becomes more desirable for tourists.
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A new study reveals that the majority of mining-related injuries and illnesses in Illinois go unreported to the federal agency responsible for tracking these events. Researchers found that only 34% of cases were captured by the Part 50 program, highlighting the need for improved reporting rates.
Researchers found widespread redactions in commercially sponsored trial protocols, making them useless for assessing ethical justification and identifying discrepancies with publications. The study highlights the mistrust in industry-sponsored drug trials and calls for unconditional access to trial protocols and data.
The revised UK Eatwell Guide lacks an evidence base and has been formulated by those with industry ties. Dr Zoe Harcombe argues that a high carb-low fat approach has contributed to rising obesity and diabetes rates in the UK.
A new Florida State University study refutes a 2007 Science study claiming that shark declines led to increased cownose ray populations, which collapsed oyster and shellfish industries. The research shows that shark populations were not as depleted as reported, and most species have recovered or are recovering.