Articles tagged with Psychiatry
Researchers found that schizophrenia patients exhibit altered brain activity in the ventro-lateral prefrontal cortex, leading to impaired ability to control working memory. This deficit is characterized by increased activation of irrelevant information, hindering cognitive function.
Researchers found that levels of severity and functional impairment among children with ADHD under 7 were comparable to those with other mental disorders. The study highlights the importance of systematic study of diagnostic criteria in representative samples.
A European teen imaging study has identified 40 predictor variables, including genetics, brain function, and personality, that can predict teenage binge-drinking with 70% accuracy. The study found that having a family history of drug use, sensation-seeking traits, and impulsivity were among the key predictors.
A new smartphone-based system detects changes in patients' behavioral patterns and transmits them to professionals in real time, facilitating patient observation and improving clinical psychiatry. The technology has the potential to greatly improve response time and efficacy of clinical psychiatrists.
A new study published in Biological Psychiatry found that individuals at high risk for addiction share similar neurobiological signatures with addicted individuals. The research suggests a common brain mechanism that promotes the use of addictive substances in vulnerable people and those with long-standing habitual substance use.
Researchers found that impulsivity plays a crucial role in cocaine addiction, with highly impulsive rats taking longer to develop habits. The study identified specific phases of addiction where dopamine receptor blockers may be effective in treating compulsive cocaine use.
Researchers at University of Maryland School of Medicine will examine the role of kynurenic acid in schizophrenia, a devastating psychiatric disease affecting one percent of people worldwide. The study aims to uncover its potential linchpin role and develop new treatment interventions.
Researchers found that anxious children had enlarged amygdala volume and increased connectivity with other brain regions, compared to non-anxious children. The study's findings provide new insights into the neurodevelopmental origins of anxiety in humans.
Researchers at Emory University discovered that individuals diagnosed with PTSD treated with ARBs or ACE inhibitors exhibited fewer PTSD-like symptoms. The study found that the medication losartan enhanced fear memory extinction, a process disrupted in individuals with PTSD.
A study sequencing the exome of 231 schizophrenia patients and their unaffected parents found that collective damage across several genes contributes to the disease. This discovery could lead to early detection and treatment strategies.
Research by Oxford University psychiatrists found that serious mental illnesses can cut life expectancy by 10-20 years, comparable to the risks associated with heavy smoking. The study emphasizes the need for governments and healthcare systems to address mental health disparities and provide accessible services.
A new study suggests that kappa opioid receptor blockers might play a role in treating alcoholism by preventing relapse during withdrawal. The KOR system is dysregulated in the amygdala of alcohol-dependent rats, leading to excessive consumption during withdrawal.
A comparative study published in Journal of the American Academy of Child and Adolescent Psychiatry found a 72.1-fold higher discharge rate for PBD in youth in the US compared to England. The disparity remains significant even after controlling for length of stay.
Researchers found that mindfulness training can help Marines recover from stressful combat situations by reducing heart and breathing rates. The study suggests that incorporating meditative practices into pre-deployment training might be a way to reduce stress-related health conditions in the US military.
A new simulation-based training program helps adults with autism improve their job interview skills and confidence. The program, developed by Northwestern University, uses virtual reality technology to provide repeated practice and feedback on interviewing skills.
A new study published in Biological Psychiatry finds that a genetic variant in the WWC1 gene may confer protection against age-related memory decline. Individuals carrying the T allele performed better on memory tasks and showed more active engagement in the hippocampus, a vital brain region for memory, with increasing age.
Researchers investigated the neural circuitry behind stress and heart disease, finding that negative emotions increase pro-inflammatory chemicals in the body. Individuals who struggled to regulate their emotions showed elevated blood levels of inflammatory cytokines and atherosclerosis markers.
Dr. Peter F. Buckley, a psychiatrist and Dean of the Medical College of Georgia, has been awarded the Kempf Fund Award for Research Development in Psychobiological Psychiatry from the American Psychiatric Association. The award recognizes his contributions to understanding schizophrenia and improving treatments.
A pilot study revealed that once-monthly NeuroStar TMS maintenance therapy induced remission in 61.2% of medication-free patients with Major Depressive Disorder after 6 weeks. At three months, 62.5% of these patients maintained response compared to 43.8% without maintenance treatment.
Childhood obesity is linked to mental health issues and decreased academic performance. Dr. Kaliebe's three rules aim to promote physical and mental well-being through healthy eating, regular movement, and reducing sensory overload.
A nationwide study found that heightened newspaper coverage after a suicide might lead to initiation of some teenage suicide clusters. The content of media reports, including prominent stories and detailed descriptions, is crucial in this regard.
A new study published in Biological Psychiatry found that deep brain stimulation increases striatal dopamine release in patients with OCD, potentially aiding their control over compulsive behaviors. The treatment's effectiveness may relate to its ability to compensate for underlying dopamine dysfunction.
A new study using MRI analysis found that patients who responded to subcallosal cingulate (SCC) deep brain stimulation showed a common pattern of three distinct white matter bundles passing through the SCC. Non-responders did not show this pattern, suggesting that precise mapping is crucial for successful treatment.
A study of almost 2,500 families found that genetic alterations in shared biological pathways are a significant risk factor for autism spectrum disorders (ASD). Individuals with ASD had more CNVs affecting genes involved in brain development and synapse function.
A new approach called DICE aims to reduce behavioral problems in dementia by empowering caregivers, patients, and health providers. The DICE method involves Describe, Investigate, Evaluate, and Create steps to change dementia patients' behavior through environmental modifications and other interventions.
Researchers found that compassionate behaviors are associated with better health and well-being as we age. The study identified three factors predictive of self-reported compassion: gender, recent suffering, and high mental resiliency.
Two new studies published in Biological Psychiatry suggest that obsessive-compulsive disorder (OCD) may be characterized by a tendency to form compulsive habits, rather than irrational beliefs. Researchers found that individuals with OCD displayed impairments in goal-directed decision making and avoidance habits.
A study published in Biological Psychiatry found that intranasal ketamine conferred an unusually rapid antidepressant effect within 24 hours and was well-tolerated in patients with treatment-resistant major depressive disorder. The results show promise for a new treatment class, targeting the NMDA glutamate receptor.
Researchers at Douglas Mental Health University Institute have discovered that dopamine is present in the hippocampus and plays a key role in this region. This finding opens up new avenues for understanding psychiatric diseases such as schizophrenia and may lead to the development of new therapeutic approaches to improve symptoms.
The new center aims to develop computational methods to understand how human cognition works and how it becomes disrupted in psychiatric disorders. The centre will combine advanced brain imaging with computational approaches to identify causes of mental health problems and develop personalized treatments.
A new study published in the Journal of Psychiatric Research found that patients injected with Botox showed substantial improvement in their depressive symptoms. The study included 74 depressed subjects who received either Botox or a placebo and showed a 47% decrease in depressive symptoms after six weeks.
Researchers found that problem-solving therapy and dietary coaching were equally effective in preventing major depression among older adults. The study's findings suggest that lifestyle interventions can have a positive effect on well-being and protect against the onset of depression.
Researchers identified mismatch negativity as a potential biomarker of psychosis risk, suggesting that deficits in this brain signal may precede the onset of psychosis. The study found that individuals at clinical high risk for psychosis who developed a psychotic disorder had reduced mismatch negativity compared to those who did not.
A new brain imaging study reveals that nicotine withdrawal weakens the connection between two key brain networks: default mode and executive control. This reduced connectivity may lead to increased difficulty in quitting smoking, with up to 80% of people relapsing after trying to quit.
The American Academy of Child and Adolescent Psychiatry has revised key parameters for evaluating and treating autism, emphasizing early diagnosis and a team approach to care. Researchers led by Fred Volkmar recommend a coordinated medical, psychological, and communication evaluation to differentiate between autism and other disorders.
A novel approach integrating psychiatrists, psychologists, and telemedicine into primary care clinics significantly reduced psychiatric and general medical symptoms. The model has been shown to improve treatment outcomes and increase access to care for rural communities with limited mental health resources.
A recent study found a significant association between advancing paternal age at childbearing and increased rates of psychiatric disorders, such as autism and bipolar disorder, as well as academic problems like failing grades and low IQ scores. The likelihood of these problems increased steadily with paternal age.
A study of US filicide arrests over 32 years found that men are as likely to kill infants as women, and stepchildren are not more likely than biological children to die at their parents' hands. The data also revealed that fathers were more likely to be the alleged murderers of adult children.
Research from Aarhus University finds that people with schizophrenia are at increased risk of developing autoimmune diseases, including psoriasis and multiple sclerosis. Infections play a determining role in this association.
Researchers have found rare gene variants on chromosome 7 that substantially increase schizophrenia risk, up to 100 out of a 1000 chance. The study also reveals a link between these genes and other disorders such as autism and intellectual development.
Researchers found that a single session of attention modification training decreased overeating in obese children by training their brains to ignore food cues. The study used implicit training methods to distract the children's attention away from food words.
A recent meta-analysis of 20 years of neuroscience research reveals significant sex differences in brain structure, with males on average having larger total brain volumes and higher tissue densities in certain regions. Females, on the other hand, have higher density in the left frontal pole and larger volumes in other areas.
Researchers found that quitting smoking is associated with lower rates of mood/anxiety disorders and alcohol use disorder. The study analyzed data from over 4,800 daily smokers and found significant improvements in mental health outcomes after quitting or reducing cigarette smoking.
Researchers found that 6-month-old infants later diagnosed with autism diverted their gaze from facial features when a face was speaking. This suggests that these infants had difficulty maintaining attention to relevant social information from an early age, which could impact their social development and communication skills.
A large international study identified an 'invisible-risk' group of adolescents with psychiatric symptoms, despite low risk behaviours being overlooked by parents and teachers. The study found that 13% of adolescents were classified as 'high-risk', while a third group showed similar prevalence of mental health issues.
A new study published in Biological Psychiatry investigates the relationship between age and neurocognitive performance in 296 healthy volunteers. The researchers found that white matter tracts developed during adolescence and young adulthood are associated with learning, memory, and planning abilities.
Two studies analyzed exomes of people with schizophrenia and healthy individuals, identifying patterns that suggest the disorder arises from combined effects of many genes. Genetic alterations tend to cluster in networks related to synaptic function, including calcium ion channels and cytoskeletal proteins.
A new longitudinal study suggests that prenatal exposure to maternal stress hormones and smoking during pregnancy increase the risk of nicotine dependence in daughters, but not sons. The study found that elevated cortisol levels and maternal smoking were associated with increased rates of nicotine dependence in female offspring.
A decade-long study shows that providing maternal-newborn skin-to-skin contact enhances child physiologic organization and cognitive control, leading to better neuroendocrine response to stress. The intervention, called Kangaroo Care, also improves children's functioning in systems sensitive to early maternal deprivation.
Researchers analyzed nearly 20,000 people with severe psychiatric illness, finding that 30% engaged in binge drinking, 75% were regular smokers, and 50% used marijuana regularly. These findings are concerning because individuals with severe mental illness tend to die younger due to health problems caused by chronic substance use.
People with IED have elevated levels of systemic inflammation markers in their blood, which correlates with aggression and impulsivity. Anti-inflammatories like Celebrex may help reduce aggression in those with the condition.
A new study published in Biological Psychiatry reveals that hippocampal volume loss in depression is caused by a reduction in glial cells, not neurons. The research uses female nonhuman primates to clarify the cellular basis of volumetric changes in the brain.
A study found that psychiatrists are increasingly refusing to accept Medicare, Medicaid, or private insurance, leaving many patients without affordable mental health care options. The number of psychiatrists is also dwindling due to retirement and a lack of new medical students choosing the specialty.
A psychiatric nurse brings a fresh perspective to caring for troubled teens in foster care with mental health issues. Research found that adding a mental health nurse can address high rates of psychotropic medication use and improve continuity of care.
Researchers found that maternal depression was associated with reduced structural connectivity in the right amygdala of newborns. This abnormal microstructure may contribute to a child's vulnerability to mental illness. The study suggests early intervention targeting maternal depression during pregnancy could reduce this risk.
A study found that cognitive behavioral therapy for PTSD reduces symptoms and affects underlying biology, reversing changes in gene expression and brain volume. The therapy was associated with improved symptoms and increased hippocampal volume and FKBP5 gene expression.
A new study published in Biological Psychiatry found that patients with PTSD are at higher risk of cardiac ischemia, with no correlation to other cardiovascular risk factors. Researchers detected elevated rates of myocardial ischemia in 17% of participants with PTSD, highlighting the need for tailored treatments.
A new study published by the CDC found that nearly half of US children diagnosed with ADHD received a diagnosis by age 6. The study also reported significant increases in medication use for ADHD among US children, with over 3.5 million taking medication by 2011-12.
A new study found that scopolamine causes rapid activation of mTOR signaling and increased synaptic connections in the prefrontal cortex, similar to ketamine. This suggests a common downstream action linked to rapid antidepressant responses.
A new study published in Biological Psychiatry reports that the compound sarcosine enhances NMDA receptor function, causing antidepressant-like effects and improving mood scores in patients with depression. The findings suggest that normalizing NMDA receptor activity may restore mood to normal levels.