A study published in Nature found that fat cells in bone marrow suppress blood production, making it harder for patients to recover from chemotherapy or radiation. Blocking this fatty infiltration could enhance blood recovery after transplant.
Researchers at the University of Montreal Hospital Research Centre have developed a new surgical technique to treat refractory epilepsy, with nine patients showing successful results. The innovative approach reduces risks and complications associated with previous insular surgeries.
A study by Baylor College of Medicine found that retinoic acid and Neurogenin2 cooperate to activate chromatin and determine nerve progenitor cells become motor neurons. This discovery may lead to generating motor neurons from different stem cells and developing tools for drug screening.
A new study evaluates expected ground motion in Seattle, Victoria, and Vancouver from earthquakes of magnitude 7.5 - 9.0, providing a tool to build or retrofit structures to withstand seismic waves. Ground motions are estimated for firm ground at the three sites, with a model that engineers can adjust for local soil conditions.
A study of 133 women with rheumatoid arthritis found that symptoms such as pain and depression significantly impacted sleep quality. Treating depression may also improve pain and medication adherence, according to researchers.
Researchers uncover neural mechanism supporting adaptability and decision-making under uncertainty, with the frontal lobe playing a critical role in tracking evidence and switching behavior.
A recent study published at SLEEP 2009 found a significant link between poor sleep quality and an increased risk of death. The research, which followed over 5,600 participants for eight years, revealed that two specific types of sleep-stage transitions were associated with higher mortality risk.
The report reveals stark contrasts in tobacco control policies and use across the US, with serious disparities remaining. States with strong programs and policies exhibit lower smoking prevalence and higher quit rates, while others lag behind, hindering overall progress.
Engineers from Penn and Sandia National Laboratories demonstrate the formation of interconnected carbon nanostructures on graphene substrate using a simple assembly process. The discovery may lead to new approach of graphene-based electronic devices.
A new study found that postpartum anxiety can delay puberty in both biological and adoptive daughters of affected mothers, regardless of maternal behavior or environment.
A new study suggests that natural hormone angiotensin 1-7 may help treat the metabolic syndrome, a cluster of risk factors increasing heart disease and diabetes risk. Angiotensin 1-7 lowered fasting insulin levels and improved triglycerides and blood sugar in fructose-fed rats.
Researchers discovered a protein profile that may accurately predict tamoxifen resistance in breast cancer patients. The study found that the extracellular matrix metalloproteinase inducer (EMMPRIN) was significantly associated with an earlier tumor progression and poor clinical outcome.
Researchers found that two-channel GES with trains of pulses can entrain gastric slow waves and accelerate gastric emptying. This treatment approach may be applicable for treating gastroparesis and normalizing gastric dysrhythmia.
A zero-tolerance policy towards underage alcohol use in the home may significantly reduce the likelihood of college students binge drinking, according to a study by Caitlin Abar. The study found that students whose parents did not permit them to drink underage were less likely to engage in heavy drinking, regardless of gender.
Exposure to low-dose BPA and estrogen increases arrhythmias in female rats and mice, a new study found. The results suggest a possible risk for female heart health due to increased levels of estrogens in the body and exposure to environmental estrogen BPA.
Astronomers have discovered a rare type of stellar explosion known as SN 2008ha, which is 1000 times more powerful than a nova but 1000 times less powerful than a typical supernova. The explosion was detected by a 14-year-old student from New York and shed new light on the nature of stellar explosions.
A recent study found that 55 percent of older adults reported sleeping less than seven hours per night, highlighting the need for improved sleep habits in this demographic. The study also revealed that individuals with depressive symptoms and poor mental health were more likely to experience short sleep duration.
Scientists have found a novel way cells fix damage to their DNA, which may also limit the effectiveness of chemotherapy agents. The discovery sheds light on a previously unknown protein called ATLs and its role in connecting two DNA repair pathways.
Researchers found a singular mutation in the FOXL2 gene that causes granulosa cell tumours, a rare and often untreatable form of ovarian cancer. The discovery provides a specific diagnostic tool and potential treatment pathway for women with this cancer type.
A new hybrid of the American chestnut tree has been developed that can sequester more carbon than other hardwood species. The trees grow faster and larger, allowing them to store more carbon in a shorter amount of time, which could help slow climate change.
The study uses radio telescope images to confirm the presence of a rotating molecular disk orbiting the young binary star system V4046 Sagittarii. The discovery expands the number of places to look for extrasolar planets, suggesting that planet formation may occur around double stars as easily as single stars.
A recent study published in The Lancet found that a treatment intended to prevent premature births in single pregnancies may be ineffective in women expecting twins. Researchers discovered an underlying difference between premature births in women with single and multiple pregnancies, which could inform improvements in treatment.
Researchers found clusters of smaller raindrops falling at speeds exceeding their terminal speed, especially during heavier rainfall. This discovery could improve weather measurement and prediction accuracy, benefiting industries like agriculture, construction, and aviation.
A study by Ohio State University found that people tend to avoid reading articles about personal issues like love and romance, but seek out information on less emotionally charged topics like finances. The study suggests that individuals use media as a way to cope with problems and escape emotional distress.
Researchers have discovered a direct relationship between carbon dioxide emissions and global warming, allowing for the estimation of climate change based on cumulative carbon emissions. The study suggests that limiting total carbon emissions is crucial to avoid dangerous climate change.
A new study led by Thomas Jefferson University researchers suggests that a minimum of three demyelinating features can be used to positively identify Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). This finding may help doctors diagnose CIDP more effectively and treat patients earlier, potentially preventing further disability.
Bisphenol A (BPA) exposure may be associated with abnormal activity in female rat and mouse hearts, potentially leading to improper heartbeat control. Researchers found estrogen receptors play a key role in this effect, which could have significant implications for women's heart health.
Alpesh Patel, a senior at MCG School of Dentistry, has identified proteins responsible for inhibiting oral cancer cell growth when exposed to blue curing light. He found that this phenomenon reduces tumor growth in mice, offering a promising alternative treatment.
Researchers identified prokineticin 2 as an appetite suppressant that works in rodents and may be used to develop an effective weight loss therapy. The molecule reduced hunger and led to significant weight loss of almost 5 percent in lean and obese mice.
The NHLBI and UnitedHealth Group collaboration aims to broaden study beyond individual diseases to address chronic diseases as they group. Early results show encouraging progress in developing portable tools and comprehensive guidelines for chronic disease management.
A new study published by Oregon State University researchers found that hatchery fish significantly impair the reproductive fitness of their offspring, even if they survive and reproduce in the wild. This could be hurting efforts to sustain wild salmon runs, scientists said.
A study published in the World Journal of Gastroenterology found that endoscopic ultrasonography (EUS) is unable to distinguish between malignant and benign gallbladder polyps smaller than 1 cm. The study suggests that EUS alone may not be sufficient for determining a treatment strategy for these small lesions.
A soil microbe uses an enzyme to produce a herbicidal compound by breaking a non-activated carbon-carbon bond in a single step. The study provides the first three-dimensional structure of the enzyme and proposes a mechanism for its task.
A recent study found that hormone therapy can alter prostate tumor properties, making them more aggressive and prone to metastasis. The treatment reduces male sex hormone production, but also increases levels of proteins enabling cancer cells to spread.
Researchers found cocaine and heroin increase antipyrine transfer across human placental tissue, compromising barrier function. This may lead to harm from more toxic substances crossing the placenta and affecting fetal health.
A new study found that nearly a third of first-degree relatives of BAV patients have enlarged aortas, a potentially serious condition. The study also revealed that 53% of BAV patients had enlarged aortas, and 9.4% of first-degree relatives had BAV.
A new animal study has identified a specific genetic cause of fetal alcohol-related developmental disorders, which may lead to targeted treatment. Fetal alcohol exposure can disrupt thyroid hormone levels, leading to neurodevelopmental disorders such as emotional behavioral disorders and deficits in learning, memory, and speech.
A study published in Significance found that private school pupils in Britain earn an average of 30% higher earnings than state school students, primarily due to higher qualifications. The study controlled for family background and other factors, suggesting that a private education offers additional benefits.
Researchers at USC School of Dentistry and Viterbi School of Engineering developed a non-thermal plasma dental probe that destroys bacterial colonies and disinfects hard-to-reach areas. The tool uses pulsed power to create a room temperature plasma with antibacterial properties.
A study by the American Academy of Sleep Medicine found that stably married women had better sleep quality than unmarried or recently widowed women. Women who had gained a partner over eight years also experienced similar subjective sleep quality but more restless sleep.
Researchers explore geologic evolution of Savu Island, active tectonic maps for the Tibet-Himalaya region, and syntectonic zoning in biotite porphyroblasts. The study also delves into the potential for explosive eruptions and growth patterns of silicic volcanoes.
Researchers have discovered a new drug, Debio 025, which is as effective as current treatment options but without the risk of infection and immunosuppression. The study found that Debio 025 protects mice from muscle-wasting diseases similar to human muscular dystrophy.
Dieter Kotschick solved Hirzebruch's problem, determining that most Chern numbers depend on algebraic structure of a variety, not topological properties. The breakthrough resolves the relationship between flexible and rigid geometric objects.
Researchers at Mayo Clinic have found that bariatric surgery may be associated with an increased risk of fractures, particularly in the hands and feet. The study, which analyzed nearly 100 surgical cases over a 21-year period, showed that 21 individuals experienced 31 fractures within seven years after surgery.
A study found that older adults (59-82 years) are more resilient to total sleep deprivation on various cognitive tasks, such as working memory and verbal encoding. In contrast, young adults (19-38 years) experienced significant declines in performance under similar conditions.
Jay Pasachoff's review article highlights the importance of ground-based solar eclipses for observing unique phenomena. The upcoming total solar eclipse on July 22 will allow scientists to advance our understanding of the solar atmosphere and make important observations.
Scientists at the University of California, Berkeley, have created tunable semiconductors using bilayer graphene, which can change its bandgap and Fermi energy with an applied electric field. This breakthrough enables the creation of reconfigurable electronic devices, potentially holding millions of differently tuned devices.
A Cornell University study found that dairy farming has decreased its environmental impact over the past 60 years, with a 41% reduction in total carbon footprint. This is due to improved efficiency and management practices.
A study on guppies led by UC Riverside's Swanne Gordon found that the fish adapted to a new environment in less than 30 generations, or eight years. The guppies developed larger and fewer offspring with each reproductive cycle in the low-predation environment, but not in the high-predation environment.
Researchers found that young mice are resistant to proteoglycan-induced arthritis, but become susceptible with age due to immunological senescence and impaired immune regulation. This study sheds light on the complex mechanisms underlying age-related changes in arthritis susceptibility.
Researchers at McGill University have pinpointed the key cellular machinery co-opted by HIV-1, allowing it to efficiently transport its RNA genome to the plasma membrane. This discovery opens up hopes for devising strategies to block the process and could lead to treatments to combat the virus.
A study published in BMC Biology has identified 59 genetic mutations in 57 genes that impact the behavior of fruit flies. Researchers found that certain mutations increase aggression, while others make the flies more placid.
A recent study found that parental presence at bedtime has a greater negative impact on infant sleep than actual co-sleeping. Children who slept in separate rooms obtained more sleep, woke less at night, and had fewer sleep problems.
Researchers at Rutgers University have discovered a potential new treatment for childhood epilepsy, using the therapeutic drug rapamycin to suppress epileptic seizures in mice. The study, published in Disease Models and Mechanisms, shows promise for treating cortical dysplasia, a common cause of childhood epilepsy.
A new parent questionnaire, Language Use Inventory (LUI), has been developed to evaluate language skills in children with autism. The LUI assesses pragmatic language development, which is critical for effective communication in everyday interactions.
Research shows a two-way link between chronic stress and poor sleep, with both factors contributing to impaired daytime functioning. Individuals experiencing more fatigue are also more likely to report high levels of stress.
Researchers at The Wistar Institute have defined a key target of an evolutionarily conserved protein that regulates the process of aging. Deacetylation of histone H4K16 by Sir2 maintains telomere stability, crucial for yeast cells to replicate and live longer.
Researchers have discovered a mechanism by which nanoparticles cause lung damage, triggering programmed cell death through autophagy. They also found that blocking this process with an autophagy inhibitor can counteract the damage, providing a promising lead for developing safety strategies for nanotechnology.
A study found that napping with REM sleep decreases negative bias and increases recognition of positive emotions, making individuals more receptive to happy facial expressions. This adaptation is critical for social interactions and professional judgments.
A Brown University professor has won a federal research grant to investigate the effectiveness of topiramate in reducing marijuana addiction among high-school students. The two-year study aims to enroll 60 adolescent males and females and assess the drug's tolerability and efficacy.