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Science News Archive September 2009 - Page 4


Page 4 of 24

Considering usual medical care in clinical trial design

A study published in PLoS Medicine discusses the challenges of designing clinical trials when there is no consensus on usual medical care. The authors recommend specific criteria for assessing proposed study designs and highlight the importance of comparing management of conditions to standard care.

SourcePLOS·JournalPLOS Medicine·DateSep 28, 2009

McMaster researchers discover a new antibacterial lead

Researchers at McMaster University have identified a novel chemical compound that targets drug-resistant bacteria, offering a promising solution to combat resistant infections. The discovery provides a new approach to tackle antibiotic resistance by blocking a specific step in the development of bacterial cell surfaces.

SourceMcMaster University·JournalNature Chemical Biology·DateSep 27, 2009

Autoimmune condition, especially combined with smoking and oral contraceptive use, massively increases risk of stroke and heart attack in young women

A study of young women with antiphospholipid syndrome reveals a significantly increased risk of stroke and heart attack, particularly when combined with smoking and oral contraceptive use. The findings emphasize the need for screening and warning young women about these cardiovascular risks.

SourceThe Lancet_DELETED·JournalThe Lancet Neurology·DateSep 27, 2009

Infant pain, adult repercussions

Researchers at Georgia State University discovered that infant pain can lead to altered brain processing of pain in adulthood. Infants who spent time in the NICU show increased opioid levels and decreased mu and delta opioid receptors, affecting pain medication efficacy.

SourceGeorgia State University·JournalFrontiers in Behavioral Neuroscience·DateSep 25, 2009

How would Einstein use e-mail?

A Northwestern University study reveals that Albert Einstein and other famous writers followed a similar pattern of correspondence, writing in cycles and adhering to a circadian cycle. The research, published in Science, demonstrates the universality of human behavior patterns across different activities.

SourceNorthwestern University·JournalScience·DateSep 25, 2009

Enzyme is key to clogged arteries

Researchers at Queen Mary University of London discovered matrix metalloproteinase-8 plays a crucial role in clogged arteries and heart disease. The study found that MMP8 enhances the effects of existing ACE inhibitor drugs, potentially reducing deaths from heart disease.

SourceQueen Mary University of London·JournalCirculation Research·DateSep 24, 2009

Major disasters tax surgical staff but may reduce costs for routine operations

A new study in Journal of the American College of Surgeons found that major disasters like Hurricane Katrina can significantly impact surgical services, leading to increased costs for routine operations. However, the same study revealed that hospitals can achieve cost efficiencies by having staff cover and share more duties.

SourceWeber Shandwick Worldwide·JournalJournal of the American College of Surgeons·DateSep 24, 2009

Nanoparticle-based battlefield pain treatment moves a step closer

Researchers at Michigan Medicine have developed a combination drug that regulates the release of morphine and its antagonist, improving pain management for patients with chronic illnesses. The nanoparticle-based system uses a pro drug to sense oxygen levels and trigger the release of Naloxone, allowing for safer treatment in combat zones.

SourceMichigan Medicine - University of Michigan·JournalBioorganic & Medicinal Chemistry Letters·DateSep 24, 2009