The University of Tennessee-managed NICS will add 300 teraflops and 200 million service units to the TeraGrid, increasing total available resources to over 800 million. Researchers can now access more resources, including the 166-teraflop Cray XT4 Athena, with improved availability for smaller jobs.
Researchers have identified a rare form of kidney disease linked to a genetic mutation in the innate immune system, causing progressive kidney malfunction and blood in urine. The condition, named CFHR5 nephropathy, has been found in over 100 people of Cypriot descent and is potentially serious but can be detected through DNA testing.
Researchers have successfully generated iPS cell-derived hepatocytes, which can recapitulate key features of inherited liver diseases and regenerate in mice. This breakthrough could lead to new treatments for liver disorders.
Researchers have described the effects of messengers on infrared spectroscopy of protonated water clusters, allowing for better interpretation of spectroscopic data. The study reveals unexpected interactions between messenger molecules and cluster structures, enabling more accurate analysis of molecular vibrations.
The new podcast series aims to raise awareness about the importance of ocean environments and the threats they face. The shows will explore various topics, including climate change, tracking sharks, whaling, and overfishing.
A new study using Spitzer data reveals a large amount of dust around three mature double-star systems, possibly resulting from planetary collisions. The research suggests that tight double-star systems might not be suitable for life to thrive due to the increased likelihood of chaotic events.
A team of researchers discovered a gene responsible for a rare and fatal disease in American Staffordshire terriers. The same gene is believed to cause a similar disease in humans. Genetic analysis led to the identification of an entirely new mutation, which can be tested in human samples to determine its connection to Kufs' disease.
International research suggests that sea levels will be 30-70 centimeters higher by 2100 even with geo-engineering efforts. However, large-scale actions like sulfur dioxide injections or mirror orbits pose significant challenges. Bioenergy with carbon storage (BECS) appears to be a more desirable option.
Walter Kohn predicts a new era in human history where solar and wind power dominate global energy, driven by growing alternative energy production and declining oil and gas reserves. International cooperation is crucial to addressing the challenges of a rapidly changing energy landscape.
Patients hospitalized with alcoholic liver disease have a significantly increased mortality risk compared to those with non-alcoholic liver disease. The study suggests that the key difference between the two conditions is alcohol dependence, which exacerbates social problems and disease progression.
A joint study by Helmholtz Zentrum München and Karolinska Institutet reveals that lipid peroxides temporarily inactivate protein tyrosine phosphatases, regulating cellular communication. This finding is crucial as aberrant activation of receptor tyrosine kinases contributes to various diseases, including cancer.
A new study suggests that mothers in violent or controlling relationships may face a decline in mental health even after leaving the relationship. Women who had more social support from friends and family showed improved mental health outcomes compared to those with less support.
University of Houston chemists Rigoberto Advincula and Mamie Moy received ACS Fellowships, recognizing their outstanding contributions to science and the chemistry profession. Their research focuses on polymer and nanomaterials, with potential applications in chemical sensors, energy transfer, and more.
A new study has found that the antiviral gene TRIM5 plays a crucial role in suppressing the transmission of primate immunodeficiency viruses, including HIV-1 and HIV-2. The researchers used rhesus macaques with different versions of the TRIM5 gene to demonstrate its ability to block cross-species transmission of SIVs.
Scientists have identified six critical amino acids in the TRIM5α protein that enable it to destroy HIV. Altering these amino acids in human cells renders TRIM5α ineffective against HIV-1 infection, highlighting a potential target for therapy development.
Four common genetic variants of the PRKCB1 gene are associated with development of end-stage renal disease in Chinese patients with type 2 diabetes. The likelihood for ESRD increased with a greater number of risk alleles, with an adjusted risk six times higher for patients with 4 risk alleles compared to those with 0 or 1.
A novel combination therapy of temozolomide and a Notch inhibitor has been shown to be highly effective in reducing tumor growth and recurrence in glioblastoma multiforme. This approach aims to target cancer stem cells, which are resistant to traditional therapies.
Hurricane Danielle has reached Category 2 status with maximum sustained winds of 100 mph, driven by low wind shear and warm waters. Forecasters expect the storm to intensify over the next 24 hours, potentially becoming a major hurricane by Wednesday.
Although immunity to mumps is high in the US, maintaining and improving vaccine coverage is crucial to prevent future outbreaks. The study found that only about 90% of the population has sufficient antibodies, which may not be enough to stop transmission.
Researchers discovered a new strategy used by bacterial pathogens like Neisseria gonorrhoeae and Escherichia coli, which delay entry into cells to prolong extracellular existence and survive. This strategy involves triggering local strengthening of the cellular skeleton that resists pathogen entry.
A recent study published in PLOS Medicine suggests that IT-based programs can support clinicians to close gaps in CVD care delivery, including risk assessment and patient self-management. The authors emphasize the need for a supportive social and political environment to fully realize the potential of these programs.
The University of Maryland has received a $1.9 million grant to acquire an 800 MHz NMR spectrometer, enabling researchers to investigate biomolecular structure and interactions with high resolution and sensitivity. This technology will advance research on RNAs, critical biological molecules involved in various diseases.
A new study found that prenatal exposure to low doses of atrazine causes prostate inflammation and delays puberty in male rats. The incidence of prostate inflammation increased significantly with the strength of the doses, while puberty was also delayed in animals exposed to atrazine.
A study published in Eurosurveillance found that nearly 60% of Norway's population had measurable immunity to the pandemic H1N1 virus by January 2010. Vaccination and infection contributed to this increased immunity, with herd immunity also playing a role.
Tropical Storm Frank has strengthened with increasing convection and tightening thunderstorm bands. NASA's TRMM satellite revealed a deep eye wall and microwave data confirmed the storm's west-northwest trajectory. Heavy rainfall is expected over south-central Mexico, with potential flash floods and landslides.
A four-week episode of increased energy intake and decreased exercise caused significant weight gain, which was mostly lost within six months. However, the intervention group showed an increased fat mass compared to baseline after two and a half years, highlighting the long-term effects of short-term behavioral changes.
The survey found that interest in receiving the HPV vaccine increased if it was available free of charge, but decreased as out-of-pocket costs rose. Convenience also played a role, with many women preferring to receive the vaccine at a doctor's office rather than a local pharmacy.
Overutilization of medical imaging services exposes patients to unnecessary radiation and adds to healthcare costs. Radiologists recommend a national collaborative effort to develop evidence-based appropriateness criteria and implement practice guidelines to reduce overutilization.
A University of Illinois professor has developed a nutritious salmon baby food for toddlers, citing the importance of omega-3 fatty acids for brain development and preventing coronary artery disease. The product's taste was found to be mild and appealing to parents, with an encouraging sensory panel response.
A new study reveals that ancient alligators and giant tortoises lived on Ellesmere Island above the Arctic Circle despite six months of darkness, with average temperatures ranging from 66-68°F (19-20°C). The research provides insights into past and future biodiversity in the High Arctic as climate change impacts the region.
A new study found that the magnitude of loyalty reward programs affects consumers' perceptions of their progress. Smaller step-sizes elicit strikingly different reactions, with those closer to the reward feeling they have made more progress.
A study of over 837,000 births in Denmark found no association between exposure to certain antiviral drugs and major birth defects. The findings suggest that acyclovir is safe for use in early pregnancy, while further research is needed on the safety of valacyclovir and famciclovir.
Researchers discovered a new species of bacteria degrading oil at an unprecedented rate without oxygen depletion. The study found that psychrophilic bacteria played a significant role in controlling deep-sea oil plumes, suggesting a potential for natural bioremediation.
A new study by Massachusetts General Hospital found that cognitive behavioral therapy significantly improved symptom control in adult ADHD patients taking medication. The skills-based approach taught patients how to cope with attention problems and manage symptoms more effectively.
A study by University of Illinois Chicago biologist Jennifer Schmidt found that a female whale shark produced 304 embryos with the same father, suggesting she stores sperm after a single mating event. This finding could indicate that mating occurs as an isolated event rather than in breeding grounds.
Researchers found that oxytocin increases trust in reliable partners but not in potentially unreliable ones. Volunteers who received oxytocin nasal spray were more generous with computer and reliable partners than those who received a placebo.
A new study in Journal of Consumer Research found that people are more satisfied with their experiences when they make personal choices, especially when the goal is pleasure. In contrast, when the goal is to achieve a higher-end consequence, there is no difference in satisfaction between those who choose and those who do not.
Researchers used Six Sigma design strategy to improve ER triage process, reducing patient waiting time and length of stay. The approach sorted patients into treatment areas based on condition severity, not arrival time, resulting in significant reductions in wait times and stays.
Researchers at the University of Kansas have discovered a new way to recognize currents of spinning electrons within a semiconductor, paving the way for superior computers and electronics. The innovation uses powerful lasers to detect spin-current in real-time, overcoming a major hurdle in spintronics research.
Caltech researchers found that flies regulate altitude by tracking horizontal edges, not the motion beneath them. This mechanism is similar to steering and was tested using an automated flight chamber with multiple cameras.
Researchers use advanced technologies to map the origin of a massive underwater hydrocarbon plume in the Gulf of Mexico, confirming it came from the Deepwater Horizon oil spill. The plume is 22 miles long and 3,000 feet deep, and its composition suggests it has been persisting for longer than expected.
Early testing and drug development are critical issues in Alzheimer's care, according to Dr. Kenneth S. Kosik, who argues that the medical system is not equipped to address patients' questions about treatment and end-of-life care.
A Galton-Darwin-Wedgwood pedigree has been found in the archives of Truman State University, revealing new insights into Charles Darwin's family life. The discovery, made by Professor Tim Berra, provides a unique window into the personal life of the famous scientist.
A randomized controlled trial of 301 patients with severe left ventricular dysfunction found no difference in major cardiovascular complications between those with and without planned balloon pump support. However, the study highlighted the importance of having a balloon pump on standby for high-risk cases.
Researchers found that human umbilical cord blood cells stabilized the brain cell environment and aided astrocyte survival after oxygen deprivation. However, the cells also had an impact on cytokine expression, sometimes suppressing inflammation and other times enhancing it.
Researchers discovered a nearly complete jaw from the hyena-like animal, Palaeonictis wingi, which evolved to half its ancestors' size during a 200,000-year period of global warming. The study suggests other factors may have played a critical role in its evolution.
Chinese scientists have developed a new cell design that uses an electric field to flip magnetization, resulting in faster and more energy-efficient magnetic memories. The design offers great potential for data storage and logic gates with ultra-low power consumption.
A study published in JAMA found that cognitive behavioral therapy (CBT) improved ADHD symptoms in adults who received medication, with greater improvement and higher responder rates compared to relaxation support. The treatment was well-tolerated and showed positive and sustained effects on ADHD symptoms.
A University of Michigan professor has developed a new type of color filter made of nano-thin sheets with precisely spaced gratings, trapping and transmitting light of specific colors. The filter acts as a polarizer simultaneously, eliminating the need for additional polarizer layers, making it simpler to manufacture.
The Big Bear Solar Observatory has achieved 'first light' using a deformable mirror, resulting in the most detailed visible light image of a sunspot ever captured. This achievement marks a significant milestone for the observatory's adaptive optics system, which will enable better studies of solar complex phenomena and space weather.
Fragrance designers like Michael Papas aim to create scents that evoke emotions and nostalgia, using complex blends of synthetic and natural substances. By tailoring their creations to specific products, they strive to connect with consumers on a deeper level, making fragrances an integral part of our daily experiences.
Walter and Eliza Hall Institute researcher Dr Marie-Liesse Asselin-Labat is unraveling the mysteries of breast stem cells, their development, and influence by oestrogen and steroids. Her groundbreaking studies aim to uncover how breast cancer progresses and why it sometimes returns.
A human study found an association between dysregulation of circadian clock genes and chronic drinking. Lower levels of mRNA in these genes were observed in alcohol-dependent patients, indicating disrupted circadian rhythm.
Scientists have developed a novel method for creating atmospheric pressure plasma jets using grounded electrodes, which differ from conventional applications. This breakthrough increases operator safety and enables the creation of jets at lower voltages, opening up new possibilities for biomedical applications.
Researchers found that exercising obese rodents showed restored signals of satiety in hypothalamic neurons, leading to decreased food intake. The study's findings suggest a new paradigm for physical activity and weight loss, reinforcing the importance of regular exercise.
Researchers have found that boosting brain levels of 2-AG, a natural painkiller, soon leads to loss of its therapeutic effect due to receptor downregulation. This discovery has implications for drug development and basic science, suggesting that more modest elevations in 2-AG may produce sustained pain relief.
A new study in the Journal of Consumer Research found that ovulating women choose sexier fashion products when thinking about other attractive local women. This unconscious behavior is driven by a desire to outdo rivals and entice desirable mates.
A study using MRI and MR spectroscopy found that abdominal and liver fat are key predictors of successful weight loss in individuals at risk of developing type 2 diabetes. After a lifestyle intervention, participants with lower baseline levels of these fats experienced greater reductions in body weight and improved insulin sensitivity.
Researchers used RAD tagging to analyze the genetic structure of Wyeomyia smithii, a pitcher plant-dwelling mosquito. The study found that post-glacial populations originated from a southern Appalachian Mountain refugium and expanded sequentially into previously glaciated areas.
High-risk patients undergoing coronary procedures with elective IABP insertion did not experience improved rates of events or death. The study found more minor bleeding in the IABP group, but no significant difference in major bleeding or MACCE.