Researchers investigated causes of software company success and failure, examining factors such as marketing, research and development, and operating capabilities. Higher operating capability has the greatest influence on survival, while firms with strong innovation-related competitive actions also have a greater likelihood of survival.
A study found that pomegranate juice reduced inflammation and oxidative stress, leading to fewer hospitalizations due to infections. It also improved cardiovascular risk factors, suggesting better heart health for hemodialysis patients.
The 2010 Golf Atlanta charity golf tournament raised $105,000 to support investigations into pancreatic cancer at The Translational Genomics Research Institute. The event drew 124 players and included a high-end auction with donations supporting TGen's life-changing research.
A new study suggests that regular exercise can improve brain function and reduce cognitive decline risk in people carrying a high-risk gene for Alzheimer's disease. Participants who exercised showed greater brain activity in memory-related regions compared to sedentary counterparts.
A recent study found that bone density remained stable for three years in patients who took a drug holiday from bisphosphonates, a popular class of osteoporosis drugs. The researchers recommend taking drug holidays after four to five years, but the study suggests that this duration may be longer, potentially up to three years.
Psychology of Women Quarterly (PWQ) is a feminist journal publishing qualitative and quantitative research on women and psychology. The journal will be published by SAGE in its 35th anniversary year, with a focus on disseminating important scholarship.
A team of researchers argues that FDA's current review process for transgenic salmon fails to consider the full impact on human health and environment. Experts call for a broader assessment of safety, including market impacts and environmental effects.
Researchers identify 47 copy-number variant regions associated with sporadic and familial aortic aneurysms (TAAD), highlighting disrupted smooth muscle function as key mechanism. The findings have significant implications for other adult-onset cardiovascular disorders, suggesting potential targets for screening and prevention.
A novel form of splicing in the cytoplasm of nerve cells dictates a special form of a potassium channel protein in the outer membrane, essential for coordinating electrical firing of nerve cells. This discovery highlights the importance of introns in regulating protein diversity and has implications for brain diseases such as epilepsy.
Researchers at Indiana University School of Medicine introduce a potent anti-tumor gene into mice with metastatic melanoma, resulting in complete remission and permanent immune reconfiguration. The gene therapy uses modified lentivirus to deliver a T cell receptor gene that recognizes specific melanoma proteins.
Researchers used tiger paw prints and feces to monitor populations, finding it more cost-effective than camera traps. The method, which costs $1,240 per site, can accurately estimate tiger numbers with a fraction of the expense.
A new international population study led by the University of Cincinnati examines the human developmental effects of environmental exposure to complex metal mixtures found in electronic waste. The research aims to identify potential preventative measures to reduce human exposures, particularly for pregnant women and young children livi...
A decade of research on the Soufriere Hills Volcano has provided new understanding of magma activity, explosive dynamics, and volcano mechanics. The CALIPSO and SEA-CALIPSO projects have generated high-resolution images of the volcano's center and adjacent crust.
Researchers at the University of Georgia have discovered a key enzyme that regulates the early growth of breast cancer cells, which can delay tumor onset and spread by blocking GnT-V activity. The study found that eliminating this enzyme reduces breast cancer stem cells, potentially leading to new drug targets and treatment options.
The new book examines how nanotechnology can exacerbate social problems while addressing pressing issues. It includes topics such as gender equity, ableism and abilities governance, and practical advice for policymakers and researchers.
Researchers found that genetics play a significant role in determining vitamin D status during the winter months. Lifestyle choices and sun exposure are more influential in maintaining optimal vitamin D levels during the summer.
UCLA researchers have pinpointed the culprit behind chronic rejection of heart, lung and kidney transplants. They discovered that HLA molecules on donor tissue provoke an immune response in the patient, leading to overgrowth of cells lining the inner blood vessels of the grafted organ.
Researchers at Mercyhurst College have identified fluoxetine, an anti-depressant chemical, in elevated concentrations at Presque Isle State Park. The presence of fluoxetine has been linked to a higher lethality to E.coli bacteria, which can pose health risks to humans.
The study identified eight categories of PTSD-related characteristics and factors, including exposure to traumatic stressors and mental health history. The work group's findings aim to improve the integration of knowledge regarding PTSD and TBI, ultimately benefiting trauma survivors.
Researchers found a 26% decreased risk of dementia for women taking hormone therapy only at midlife, while late-life use increased risk by 48%. Midlife and late-life use had similar dementia risks for women not on hormone therapy.
A team of researchers has developed a novel identification system for mouse embryos by injecting silicon barcodes into their perivitelline space. The system enables the tracing of individual embryos during in vitro fertilization and embryo transfer procedures, reducing risks associated with human gamete and embryo identification.
The Deep Impact spacecraft flew through a 'snowstorm' of fluffy particles on its encounter with comet Hartley 2, providing new insights into the nature and composition of comets. The spacecraft's High Resolution Imager captured images of clouds of large ice particles surrounding the nucleus, revealing a unique process driven by CO2 jets.
Researchers have achieved a significant milestone by trapping 38 antihydrogen atoms for more than one-tenth of a second using the ALPHA experiment. This achievement marks a crucial step towards studying the properties of antihydrogen, which could provide insights into the universe's mysterious lack of antimatter.
The journal aims to strike a balance between brevity and detail in its new key findings page, which highlights the most significant scientific discoveries published each month. The service provides bite-sized chunks of information on article titles and abstracts, allowing users to scan for new research findings.
Research from University of Michigan Marketing Professor Scott Rick shows that tightwads and spendthrifts tend to spend about the same amount on gifts during Black Friday. This discrepancy arises due to differences in psychological pain associated with spending decisions, particularly when purchases are optional.
Scientists have developed a novel system called MultiLabel to efficiently label mammalian cells with multiple fluorescent markers, allowing for faster disease process analysis. This technique enables precise labeling of cellular components involved in various diseases, facilitating accelerated drug development and screening.
A new study has uncovered the role of Sortilin in regulating Progranulin levels in neurons, which may hold promise for treating frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). The research found that Sortilin-mediated PGRN endocytosis is a key pathway underlying FTLD-TDP pathophysiology.
Scientists search for chemical solutions to combat the fungus without harming bats, highlighting their ecological importance.
A new dry powder HPV vaccine offers improved effectiveness and lower costs by targeting mucous membranes directly, reducing contamination risks. This innovative delivery method aims to expand HPV vaccination access to more people globally, particularly in developing countries.
A study found that yearly mammogram screening in women under 50 with a family history of breast cancer can lead to smaller, less aggressive tumors and improved survival rates. The research suggests that this approach could prevent up to two deaths from breast cancer per 10,000 screens.
Scientists identified 28 glycoproteins in Italian Chardonnay, similar to known allergens, sparking hope for low-allergenic wine development. The discovery could lead to reduced allergy symptoms in millions of wine drinkers worldwide.
A study by researchers at the University of Washington found that 90% of high-functioning children with autism spectrum disorders showed discrepancies between their IQ score and performance on standardized tests. These children often have above-average academic abilities, suggesting that traditional IQ scores may not be an accurate pre...
Researchers created a machine-learning model called DiaTM that learns vernacular terms for health problems and symptoms, improving medical website performance. The system achieves a 25% improvement in nDCG, a scientific term referring to the relevance of information retrieval.
A new imaging method has been developed at Stanford to quickly and accurately locate and count the myriad connections between nerve cells in unprecedented detail. The method, array tomography, combines high-resolution photography with specialized fluorescent molecules to capture information and converts it into imagery.
Researchers from Georgetown University Medical Center presented findings on how a gene regulating dopamine affects communication between brain regions during memory tasks. They also explored the neural processing disrupted in neurological disorders like semantic dementia and stroke, as well as the mechanisms underlying tinnitus.
A new study finds that patients with knee osteoarthritis who also experience lower back or foot pain report more severe knee pain. Additionally, having multiple pain locations, including elbow pain, is associated with higher knee pain scores.
William Ja, a Scripps Florida scientist, received $60,000 grant from the Glenn Foundation to continue his work on longevity-enhancing manipulations. He also received a two-year grant of approximately $200,000 for non-surgical sterilization methods for dogs and cats through the Found Animals Foundation.
Researchers at Queen's University have discovered a way to detect oxygen in complex biomolecular systems, revolutionizing the study of proteins, DNA, RNA and other molecules. This breakthrough allows scientists to examine all four major elements and learn more about their chemical structure and interactions.
Scientists have developed a biodegradable foam plastic substitute using milk protein and clay. The new material is strong enough for commercial use, with almost a third of the material breaking down within 30 days.
A global network to analyze the impact of science on society has been created following an international conference at Universidad Carlos III de Madrid. The network will facilitate communication and collaboration among researchers from diverse fields, including philosophy, sociology, economics, and more.
Researchers at Northwestern University have found a way to mimic estrogen's effects on brain cells without increasing cancer risk. By activating an estrogen receptor, they increased the number of connections between brain cells, improving mental performance.
Researchers at the University of Missouri have developed an intervention strategy that improves medication adherence by three times more than previously studied techniques. The Continuous Self-Improvement strategy involves counseling patients to understand how taking medications fits into their daily routines.
Scientists have discovered two new compounds that show promise as treatments for botulism poisoning, building on a multiple sclerosis drug. The compounds did not enter the brain and showed good potential in mice paralyzed by the toxin.
Researchers discovered that bacteria produce unique proteins to inhibit growth and end life of other bacteria, suggesting a primitive form of kin selection. These proteins are acquired through horizontal gene transfer, allowing bacteria to adapt and evolve.
Rensselaer students Casey Hoffman and Jaron Kuppers won the top prize with their SET process, which offers a new method for curing advanced composites using less energy and cost. The process has the potential to trim manufacturing costs and widen the playing field of businesses that can afford to research and manufacture these materials.
A new study reveals that adenosine tri-phosphate (ATP) works in synergy with lactic acid to sense muscle pain. The researchers found that ATP increases the sensitivity of acid sensing channel #3 (ASIC3) on sensory neurons, helping to explain why acid alone is unable to trigger ischemic pain.
A new device can analyze samples thousands of years old in minutes, helping archaeologists determine ancient activities. It works by lifting off spectral fingerprints with infrared light and analyzing molecular peaks to tease out material origin differences.
Scientists at the University of Cambridge have made breakthroughs in the Haber-Bosch process, aiming to produce fertilizers more efficiently while reducing energy consumption. Their innovative approach uses single-crystal iron samples and ultra-high vacuum conditions to achieve significant improvements.
Dr. Benjamin Kile received the Science Minister's prize for his innovative research into cancer, stem cells and blood cell production. His discoveries have transformed our understanding of platelet biology and hold promise for developing new treatments for life-threatening conditions.
The University of Guam and University of Massachusetts-Boston are partnering to offer a four-year Master's Degree Program for educators in the Pacific, with up to 20 scholarships available. The program aims to enhance educational capacity for students who are blind or have visual impairments.
Reduced pericyte levels have been found to disrupt blood flow and worsen the breakdown of the blood-brain barrier, allowing toxic substances to reach brain tissue. This can lead to structural damage to neurons, impaired learning and memory, and increased risk of neurodegenerative diseases like Alzheimer's.
Researchers found compelling evidence for the birth of a stellar mass black hole in the type IIL supernova SN 1979C. The study proposes that the late time glow of the supernova is consistent with a black hole accreting material from either a fallback disk or a binary companion.
A study published in the Journal of Advanced Nursing found that a nurse practitioner-led spinal clinic achieved 100% agreement on clinical diagnosis and 96% patient satisfaction. Patients waited an average of 12 weeks to see the nurse practitioner, significantly shorter than conventional clinics.
Milan Begliarbekov, a doctoral candidate at Stevens Institute of Technology, has found unique applications for graphene. His research uses µ-Raman spectroscopy to differentiate between monolayer and bilayer graphene, and establishes a new signature of Klein tunneling in graphene heterojunctions.
A multidisciplinary clinic approach to treating aggressive prostate cancer has been shown to improve survival rates and reduce distress among patients. The study, conducted over 15 years at the Kimmel Cancer Center, found that a team of specialists working together can provide more effective treatment options and better patient outcomes.
Research by ecologists at Brown University found that faster water flow speeds promote greater diversity of invertebrate species on rocks under the ocean. The study showed consistent results across three regions, suggesting that water flow is a key factor in determining marine biodiversity.
The Symplicity HTN-2 trial shows that deactivating nerves in the kidneys using radiofrequency energy can significantly reduce blood pressure in patients with treatment-resistant hypertension. The study found a large reduction in systolic blood pressure, and the technique was applied without major complications.
A new analysis by an international team of fisheries scientists found that the widely adopted indicator, average catch trophic level, led to inaccurate conclusions in 13 out of 29 trawl surveys from 14 ecosystems. The study suggests that this measure is a woefully inadequate assessment of marine fisheries health.
The article discusses ongoing research to improve influenza vaccines, including the development of novel production technologies and approaches such as recombinant virus proteins and universal flu vaccines. These efforts aim to provide better protection against multiple strains of influenza and novel flu viruses in the future.
Scripps Research scientists devise broad new technique for screening proteins, enabling efficient detection of functional sites. The method may have applications in basic research and drug development, allowing researchers to characterize unknown proteins and identify new functional sites on existing ones.