A Canadian alliance led by Dr. Andrea Tricco aims to strengthen the health-care system by providing patients with access to relevant scientific evidence. The alliance will answer at least 100 questions over a five-year period using knowledge synthesis and collaboration with researchers, clinicians, and policy-makers.
A NASA satellite detected a strengthening Hurricane Lee, with colder cloud top temperatures indicating stronger storms. The storm's eye cleared out and warmed, while the eyewall cloud tops cooled to -81.4 degrees Fahrenheit, suggesting heavy rainfall potential.
A global review of 28 studies found that opioid substitution treatment (OST) reduces hepatitis C infection risk by 50% and when combined with high coverage needle syringe programmes (NSP) reduces risk by 74%. OST is essential for comprehensive strategies to prevent HCV transmission and disease.
Professor Patricia Dos Santos of Wake Forest University has received a $680,000 NSF grant to support her biochemistry research and mentorship program. The grant enables her to work with graduate students and undergraduate researchers from local colleges, providing hands-on research experience and career development opportunities.
A researcher is investigating whether mid-day napping benefits learning in young children and helps them cope with emotions. The study will explore the mechanisms of sleep and its effects on cognitive functions, emotion processing, and behavior.
A new study found that customizing warfarin dosing to a patient's genetic and clinical profile reduces adverse outcomes compared to clinically-guided dosing. The study involved 1,650 patients undergoing hip or knee replacement, who were randomly assigned to either genotype-guided or clinically-guided dosing.
A seven-year review found that more frequent rotation of plant inspectors at medical device manufacturing facilities leads to fewer product recalls. The study suggests that rotating investigators reduces the risk of recalls by 21-57% depending on the number of visits, providing an objective assessment of a plant's quality.
Researchers found that flu viruses can evolve rapidly due to their ability to hijack host chaperone proteins, which help mutated viral proteins fold and function. Targeting these proteins could delay viral evolution and decelerate escape from existing drugs and vaccines.
Researchers demonstrate a nanoscale technique that uses semiconductor quantum dots to bend photons to the wavelengths used by today's popular C-band standards. This breakthrough enables entangled photons to impact cryptography and secure satellite communications.
A recent study found that most milk-alternative drinks have inadequate levels of iodine, making them an unsuitable substitute for cows' milk. Iodine is essential for thyroid hormone production and fetal brain development during pregnancy.
A study by Anna Kirstine Winthereik shows that general practitioners who prioritize home visits reduce the time terminally ill cancer patients spend in hospitals and increase the likelihood of them dying at home. The study also highlights a positive correlation between frequent home visits and reduced hospital bed days.
Emergency room patients prescribed opioids are less likely to become long-term users, with prescriptions exceeding 7 days decreasing by 84-91% in ER settings. This study suggests that adherence to CDC guidelines may contribute to reduced opioid misuse.
A new Iowa State University study reveals that having a TV or video game system in the bedroom can lead to decreased reading time, sleep deprivation, and an increased risk of obesity. The research also found that children who watched violent programs on bedroom media were more likely to exhibit physical aggression.
A UBC study identified 294 marine species that will be highly vulnerable to climate change by 2050. These species have limited temperature ranges, restricted geographic ranges, and specific habitat requirements making them more susceptible to climate change.
Research led by Washington University School of Medicine finds that prescribing antibiotics in addition to lancing and draining staph-infected areas reduces the risk of recurrent infections. Clindamycin was found to be more effective at eliminating staph colonization than other antibiotics.
Recent advances in engineering bacterial outer membrane vesicles have demonstrated protection against infection by various bacterial species in animal models. These biologically-derived nanoparticles could function as a platform technology for vaccine development and targeted compound delivery.
Researchers found that patients with pre-existing psychiatric diagnoses had higher acute and follow-up costs, particularly in emergency department and hospital outpatient costs. Addressing psychiatric comorbidities proactively may mitigate cost differences for these patients.
A new IASI channel selection method has been developed to improve weather forecasting accuracy by reducing bias in humidity forecasts. The method used a one-dimensional variational analysis approach to select 200 new channels from the available 314 channels.
A new study published in Nature Human Behaviour found that reducing systematic and aggressive policing measures can lead to a decline in major crime complaints. The researchers analyzed data from New York City's NYPD during a period when proactive policing was halted, revealing a 3-6% decrease in reported serious crimes.
Researchers will systematically identify resources that successful patients use to overcome HIV challenges, developing a novel public health measure called resilience. The goal is to design interventions to increase suppressed HIV viral load among patients.
Researchers at Osaka University have developed a highly efficient way to make unique screw-like chemicals that can produce pure mirror images of other molecules. The new sulfur-containing group could be used as asymmetric catalysts in reactions.
A Sam Houston State University researcher is studying child abuse cases filed directly with police, aiming to strengthen the safety net for abused children in Texas. The study aims to determine if every child in need receives critical services at an earlier point in the investigation.
A recent study has found no evidence of auditory nerve injury or permanent hearing difficulties in young adults after attending a loud event. The research suggests that traditional hearing tests may not detect hidden hearing loss caused by recreational noise, highlighting the need for alternative testing methods.
Researchers have discovered a possible biomarker, CCL11, that may allow CTE to be diagnosed in living individuals. The study found elevated CCL11 levels in the brains of former football players with CTE compared to non-athletes and those with Alzheimer's disease. This discovery could lead to targeted treatments for CTE sufferers.
A recent study by Duke Cancer Institute found that ACA Medicaid expansion significantly reduced uninsured rates among white patients and those living in higher-income areas, but had little impact on black patients and residents of high-poverty areas. In contrast, states without expanded Medicaid saw a decline in uninsured rates primari...
Researchers found that warming climate conditions could lead to significant economic and healthcare costs due to increased occurrences of Vibrio bacteria in Chesapeake Bay. The study used a new downscaling framework to project future increases in Vibrio species, highlighting the need for models of climate impact on estuarine environments.
Tropical Depression Pilar weakened to a remnant low pressure area, with disorganized clouds and weak convection south of Baja California. The National Hurricane Center forecasted scattered showers and thunderstorms in the region, yielding heavy rain.
Researchers found that pigeons can switch between two tasks as quickly as humans, with a slight advantage in some cases. The key to this advantage lies in the dense packing of neurons in the avian brain, allowing for faster information processing and task switching.
NASA's Aqua satellite provided infrared data on Hurricane Maria, revealing the coldest cloud tops and strongest storms were located in the eastern quadrant, which could produce heavy rainfall. The storm is expected to weaken due to cooler sea surface temperatures.
Researchers have developed a new method to simulate infrared spectra using artificial neural networks, reducing simulation time from thousands of years to minutes. This breakthrough enables the analysis of complex chemical systems and paves the way for widespread adoption in various fields.
Women earn less than men regardless of rank or training, with women leaving careers due to advancement issues. Underrepresented minorities are underrepresented in senior positions and promotions across all levels
A new study published in Circulation Research found that umbilical cord-derived stem cells improved heart muscle function and quality of life for patients with stable heart failure. The treatment was safe and showed significant improvements over placebo, paving the way for a promising new therapy.
The Serum Institute's rotavirus vaccine, ROTASIIL, demonstrated significant efficacy against severe rotavirus gastroenteritis, reducing severe diarrhea by over a third. The vaccine showed nearly 55% efficacy against the most severe cases, which can lead to dehydration, hospitalizations, and deaths.
Researchers at Ohio State University Wexner Medical Center have discovered a DNA-level biomarker that can predict overall survival for patients with anaplastic astrocytoma, a rare form of brain cancer. The study found that MGMT promoter methylation status is significantly associated with overall survival outcomes.
Researchers used advanced synchrotron measurement setup to study spin dynamics of ferrimagnetic thin films containing different proportions of gadolinium. They found that varying composition dramatically changed response to laser pulse, leading to improved switching speeds and precision.
The National Institute of General Medical Sciences awards LSU Health a $1.4 million grant to prepare individuals from underrepresented backgrounds for PhDs in biomedical sciences. The program aims to enhance the diversity of the biomedical research workforce and provide hands-on exposure to medical research.
A specific mutation in the DNA of the fungal pathogen Cryptococcus deuterogattii increases its mutation rate, allowing it to rapidly develop resistance to antifungal drugs like FK506 and rapamycin. This hypermutator trait is likely widespread among pathogenic fungi.
Postpartum depression affects over 5% of women after childbirth, with a risk of recurrence 21% for those with hospital contacts or antidepressant use. Treatment duration varies, with 27.9% still in treatment a year after first treatment.
Researchers found ED opioid prescriptions were 44% less likely to exceed a three-day supply and 46% less likely to progress to long-term use. Patients in non-ED settings received higher doses, with one in five exceeding CDC guidelines, leading to a higher risk of long-term use.
Researchers discovered two predator bacteria, Vampirovibrio and Bdellovibrio, in cystic fibrosis patients' lungs, which may prevent colonization of disease-associated bacteria. The findings indicate a more complex lung microbiota than previously thought.
Researchers have developed a web app capable of producing 3D facial reconstruction from a single 2D image. The technique, using Convolutional Neural Networks, allows for arbitrary facial poses and expressions, with over 400,000 users already trying it out.
The committee's efforts focus on increasing the number of sites hosting research studies, expanding potential study volunteers, and reducing duplicated efforts. By leveraging public-private partnerships, they aim to develop effective medicines for children with kidney disease.
Scientists at KAUST and Oxford University have created a method to produce centimeter-scale, highly pure perovskite crystals by exploiting surface tension. This technique enables the growth of large-area perovskites without being limited to specific metal cations.
A team of researchers at Harvard Medical School has created a stable version of the segmentation clock in a petri dish, revealing its dynamic nature and control mechanisms. The discovery could lead to improved understanding of scoliosis and other human spinal defects.
A study using temporary tattoos helped medical students develop a greater understanding of skin cancer and empathy for patients. The study found that wearing a realistic tattoo provided a powerful experience, allowing students to consider the person behind the illness.
Researchers funded by Morris Animal Foundation found that the rabies vaccine reduces mortality from all causes in dogs by 56 percent, particularly among young dogs. This non-specific protective effect may have implications for human medicine as well.
Scientists at Stanford University have created a novel method for separating chiral molecules, which are essential in pharmaceuticals and agriculture. By utilizing circularly polarized light, the researchers can distinguish between left- and right-handed forms of these molecules, enabling safer and more effective drugs.
A randomized experiment found that children who watched a PG-rated movie clip containing guns played with a disabled real gun longer and pulled the trigger more often than those who saw the same movie without guns. Children who saw the movie containing guns also played more aggressively and sometimes fired the gun at people.
A new method targets the appetite-stimulating hormone ghrelin to prevent post-diet weight gain in mice. Mice treated with a virus expressing butyrylcholinesterase (BChE) gene therapy showed reduced weight regain and improved glucose tolerance after switching back to an unrestricted diet.
Researchers have developed a self-righting robot inspired by the legless jumping mechanism of click beetles. The beetle's unique hinge-like structure allows it to flip back onto its feet after being knocked over, and the researchers aim to integrate this mechanism into their robot prototypes.
Researchers found reduced myelin coating thickness and molecular alterations in brains of adults who experienced severe childhood abuse. These changes may contribute to depressive disorders, suicidal behavior, and altered emotional processing.
A study by Drexel University researchers found that violent crime and disorderly conduct rates increased when daily temperatures were higher, with the highest rates in warmest months. Temperatures above 70 degrees led to 16% higher violent crime rates and 23% higher disorderly conduct rates compared to cooler days.
A new study published in CMAJ found that organ donation in Ontario rose 57% since 2006, primarily due to the introduction of a policy allowing donation after circulatory functions cease. The study suggests that this increase has led to a positive impact on transplant activity and the overall number of donors.
Researchers have identified a shared neural mechanism for building confidence across multiple senses, including vision, audition, and touch. The study's findings support the supramodality hypothesis, suggesting that confidence estimates share a common format in the brain.
A leading neuroscientist has developed an innovative program to treat Alzheimer's disease with a novel N-of-1 design that individualizes medicine for each patient. The approach aims to identify person-specific risk factors and apply customized interventions to prevent dementia.
Rice University scientists developed a superhydrophilic membrane that can remove more than 90% of hydrocarbons, bacteria, and particulates from contaminated fracking water. The filter keeps emulsified hydrocarbons from passing through, allowing for reuse and reducing the need for storage or transportation.
A Massachusetts General Hospital study suggests that participating in the Supplemental Nutritional Assistance Program (SNAP) can lower annual health care costs by $1,400 per person. SNAP provides a monthly benefit to purchase certain food products and has been found to reduce food insecurity.
Researchers found that signalling by prolactin to its receptors is essential for mothers to show vital maternal nurturing behaviour towards their young. This discovery may explain why some animal species abandon their young and highlights the importance of prolactin in establishing a bond between mother and baby.
A study found that a religiously sensitive educational effort increased Muslim women's perceived likelihood of getting mammograms and their eventual receipt of breast screenings. The intervention, held in mosques, addressed cultural and religious barriers to mammography, reframing modesty as not the ultimate value.
A novel image analysis tool allowed researchers to observe which cells become 'losers' in cell competition and die, while others survive with higher Myc levels. This discovery reveals the importance of Myc levels in maintaining pluripotency during mammalian embryonic development.