Researchers discovered a potentially devastating foot disease in Chile's endangered huemul deer population, with severe pain and death caused by the condition. The study's findings highlight the need for improved monitoring and collaboration to help protect the critically endangered species.
Researchers at Georgia State University discovered that societal expectations around gender roles can alter the human brain at a cellular level. This finding suggests that epigenetic marks in the brain drive differences between males and females, influenced by gender identity rather than just biological sex.
Researchers developed a drug resistance index to track global trends in antibiotic therapy effectiveness. The study found that high-income countries generally have lower rates of resistance, while low- and middle-income countries face greater challenges due to limited access to newer drugs.
A new study found that transfer RNA-derived fragments play a significant role in gene expression, differing by cancer type and sex of the patient. The mitochondrion is involved in these interactions, particularly with repetitive elements.
New research finds elevated levels of fatty acid transporter protein 2 (FATP2) in immune-suppressing cells, which can slow tumor growth and aid cancer treatments. The study also discovered an energy-granting lipid that FATP2 produces and traffics into cells, leading to its potential as a therapeutic target.
Scientists at the University of Hawaii have developed a technique to measure living coral on reefs by analyzing DNA in small seawater samples. This new method, known as metabarcoding, can track changes in coral reef health and detect rare species.
A Harvard University study explores the genetics behind the evolution of flightless birds, finding that different species turn to similar regulatory pathways when evolving flight loss. The team discovered a shared suite of morphological changes that led to a similar body plan across all flightless bird species.
The team tested two devices, one that can change conformation in the esophagus to exit after drug delivery and another that can reside in the stomach until intentionally triggered. The devices were inspired by design principles of transformable materials and showed promise for fast and robust response.
Climate change could cause Western Hemisphere cloud forests to shrink and dry by 60-80% in as few as 25 years. The loss of clouds would nearly disappear the highly diverse alpine ecosystems above these equatorial cloud forests, known as páramo.
A Monash University study found that exposure to coffee-related cues can trigger cognitive benefits, such as increased alertness and energy levels, in participants from Western cultures. The research used mental construal theory and demonstrated the power of psychological associations in shaping our thinking and behavior.
Researchers at Yale University successfully restored circulation and cellular activity in a pig's brain four hours after its death using a specially designed chemical solution. However, the treated brain lacked recognizable global electrical signals associated with normal brain function.
Researchers have discovered that tsunami-like solitary waves, known as clusters, move in synchrony with each other. The findings were made possible by observing how the waves behave when they occur in a series, revealing intriguing patterns of movement and coordination.
The US Army has awarded up to $50 million over five years to eight academic teams pursuing basic research across various scientific disciplines. The teams will study topics including heat energy transfer, plant and pollen distribution, and the restorative effects of sleep.
A new Yale study uncovers key relationship between storm events, ecology, and topography in moderating greenhouse gas release from rivers and streams. Concentrations of three greenhouse gases increase during rainstorms in wetland streams but decrease or remain constant in forested streams.
Dr. Nicole Brandt will receive the 2019 Dennis W. Jahnigen Award for her dedication to training health professionals in care for older adults. She has developed a geriatrics and palliative care pathway, an accredited geriatrics residency, and secured funding for innovative programs supporting older adults.
A novel plasma water treatment method by electrical discharge has been developed, producing drinking water as suitable for consumption as ozonation, without carcinogens or high costs.
A CABI-led study found that women face unequal access to agricultural advisory services, hindering their contribution to farming. The research proposes training female extension workers as 'lead contact' farmers to improve information dissemination and reduce gender inequalities.
A new AI system called FocalNet has been developed to aid radiologists in detecting prostate cancer, achieving 80.5% accuracy in reading MRI scans. The system uses machine learning to evaluate tumors and predict their aggressiveness, providing diagnostic guidance to less-experienced radiologists.
Regular ultrasounds at 36 weeks' gestation can identify undiagnosed breech presentations, reducing the risk of complications for both mothers and babies. By performing these scans, hospitals could potentially save thousands of pounds annually while improving patient outcomes.
The US Preventive Services Task Force now finds no evidence to support or refute screening for elevated blood lead levels in asymptomatic children under 5 years old and asymptomatic pregnant women. This recommendation updates the 2006 statement and is based on a review of existing literature.
The 2017 pneumonic plague outbreak in Madagascar was characterized by a dominance of the pneumonic form, which accounted for 78% of reported clinical cases. The number of confirmed cases doubled every five days after the initial stage of the outbreak.
Researchers have discovered a potential new treatment for renal fibrosis by selectively activating AT1 receptors on T cells, which may help limit scar formation in the kidney. The study found that activating these receptors mitigates renal fibrogenesis by inhibiting Th1 differentiation and renal accumulation of pro-fibrotic macrophages.
A new study in Heliyon identifies distinct opinion patterns on positional issues among Canadian voters, suggesting a micro-targeting marketing strategy could be effective. The research found that many Canadians have strong opinions on divisive issues, comparable to conventional vote predictors like party identification.
A new study finds that climate change will lead to the extinction of both seaside and saltmarsh sparrow species, with saltmarsh sparrows facing local extinction in as little as 30 years. Rising sea levels will reduce available habitat and increase flooding rates, making it difficult for these birds to thrive.
A new study found that having Black female role models in STEM is crucial for black women college students to feel a sense of belonging. The research, led by Indiana University-Purdue University Indianapolis School of Science, also discovered that seeing a Black male scientist can signal more belonging, while high stigma consciousness ...
Joanne Kurtzberg, MD, has been awarded the 2019 Bernard Sanberg Memorial Award for her groundbreaking work in pediatric hematology and regenerative medicine. The award recognizes her clinical trials that have led to positive results in treating adult ischemic stroke patients with cord blood therapy.
A new approach, PRO-cision Medicine, uses patient-reported outcomes to personalize cancer care. This method provides valuable information on patients' symptoms and functioning, guiding clinicians in making informed decisions.
Researchers found that high testosterone and cortisol levels are associated with increased aggression in boys, while girls with high empathy levels exhibit lower aggression. The study suggests a complex interplay between hormones and empathy in shaping aggressive behavior in children.
Research reveals that white sharks immediately vacate their preferred hunting grounds when orcas arrive, resulting in no shark sightings for up to a year. Elephant seal colonies also indirectly benefit from these interactions, with significantly reduced predation events during the orca presence period.
Researchers have identified a pattern of brain activity reflecting anger experienced during dreaming. The study found that frontal alpha asymmetry is related to anger in both wakefulness and dreams.
A study found that metformin reduces left ventricular hypertrophy (LVH) in prediabetic and pre-existing heart disease patients, leading to lower cardiovascular risks. The MET-REMODEL Trial showed significant benefits of metformin on LVH, blood pressure, oxidative stress, and body weight.
Researchers identified 11 primary challenges faced by therapists, including unrealistic agency expectations, inadequate support, and heightened case complexity. Therapists reported needing targeted trainings to improve service delivery for children and families.
DNDi and Atomwise collaborate to develop first-in-class treatments for Chagas disease using AI, delivering drug-like compounds that will undergo further optimization and potential drug development. The research aims to address a public health challenge affecting millions worldwide.
A study published in Biological Conservation highlights the importance of tree dens for pandas raising infants in native habitats. Tree dens provide a more stable microclimate than cave dens, facilitating offspring survival. This research emphasizes the need to preserve large old trees for giant panda conservation.
Researchers discovered multiple potential targets for glioblastoma by systematically profiling patient-derived brain tumour cells. They found that adult glioblastoma cells rely on genes important for brain development in infancy, highlighting the need for new research to understand the developing human brain.
Researchers found that the nutrient composition of interstitial fluid surrounding pancreatic tumors differs from blood and culture medium used to grow cancer cells. This discrepancy suggests growing cancer cells in a more similar environment could help predict how experimental drugs will affect cancer cells.
A new study from Iowa State University found that same-sex couples are less likely to be approved for mortgages, with approval rates ranging from 3-8% lower. Same-sex applicants also faced higher interest and fees, with the difference adding up to $86 million annually.
The PCV10 pneumococcal vaccine significantly reduced the incidence of serious pneumococcal disease among children under five years old, with a 92% decline in cases involving the ten targeted strains. The vaccine also provided herd immunity benefits by reducing disease transmission among older, unvaccinated age groups.
A study published in PLOS Biology found that oxytocin administration can block excess drinking in alcohol-dependent rats, suggesting a potential novel pharmaceutical intervention for treating alcohol-use disorder. Oxytocin also blocked altered GABA signaling in the brain region affected by alcohol dependence.
The University of Wisconsin-Madison School of Pharmacy has designed new small molecules that can stop the replication of equine encephalitis viruses in the brain. These compounds have shown a high survival rate in mice, even when delayed treatment is administered.
A study found that carnivores interact with each other more frequently when sharing green spaces in suburbs, contrary to previous theories. Preserving green space is crucial for wildlife species, providing cover, food, and navigation without human danger.
Researchers have shed light on how leukemia cells become resistant to drugs and describe a potential solution using two drugs in combination. The study identifies the genes responsible for resistance, revealing that cancer cells overcome the lack of asparagine by breaking down proteins.
Researchers developed a novel bioelectronic treatment that significantly reduces swelling and inflammation in rheumatoid arthritis patients. The non-invasive vagus nerve stimulation treatment inhibits the production of cytokines, proteins that mediate inflammation.
A recent study published in JAMA found that magic mouthwash significantly reduced pain from oral mucositis, a common side effect of radiation therapy for head and neck cancers. The treatment, which contains diphenhydramine, lidocaine, and antacids, was well-tolerated by patients and outperformed placebo.
Researchers developed a smart polymer that senses high oxidant levels and administers just the right amount of antioxidant to restore balance. The polymers successfully recovered water fleas' heart rates when exposed to sublethal concentrations of hydrogen peroxide.
A workshop published a roadmap for AI in medical imaging, highlighting key research themes and prioritizing foundational machine learning research. The report emphasizes the need for collaboration among professionals, funding agencies, and institutions to develop innovative imaging technologies.
The University of Texas at San Antonio (UTSA) researchers have each been awarded a National Science Foundation (NSF) Faculty Early Career Development (CAREER) Award, totaling $2 million. The awards will support various projects, including energy planning and management for smart cities and biomedical engineering research.
Courtney Balentine, MD, MPH, and Candace Yvonne Parker-Autry, MD, will receive the Jeffrey H. Silverstein Memorial Award for Emerging Investigators in Surgical and Related Medical Specialties. Their research focuses on improving care for older adults through innovative approaches, such as Virtual Acute Care for Elders (ACE) and phenoty...
Researchers at UTA work with TxDOT to improve soil monitoring and predictive modeling, reducing slope failures and increasing road resilience. The projects also aim to enhance the transportation system's reliability and safety.
A new study published in the Journal of Allergy and Clinical Immunology: In Practice suggests that oral immunotherapy is safe for preschool-aged children with peanut allergies. Researchers followed 270 children who received oral immunotherapy and found that 90% reached the maintenance stage successfully.
The GRACE satellite mission has revealed significant changes in Earth's gravitational field, providing insights into the terrestrial water cycle, ice sheet and glacier mass balance, and sea-level rise. The data highlights the effects of global warming on ice sheets and glaciers, as well as changes in freshwater storage and ocean dynamics.
A team of scientists measured the puncture performance of viper fangs using a custom-built machine. The study found that the angle of the fang's tip contributes most to its sharpness, with narrower tips performing better than wider ones.
Researchers at the University of Maryland have developed a self-cleaning solar evaporator made of wood that can efficiently produce clean drinking water from salty water. The device uses interfacial evaporation technology and minimizes maintenance needs, making it suitable for off-grid water generation in low-income countries.
A recent study from Binghamton University found that negative behaviors like substance abuse can lead to a cycle of poor lifestyle choices, mental distress, and low grades. Positive behaviors, on the other hand, support brain chemistry profiles that promote mood maturity and rational thinking.
The TESS mission has discovered its first Earth-sized exoplanet, HD 21749c, which orbits a nearby star in just 7.8 days. The planet is likely a rocky, uninhabitable world with surface temperatures of up to 800 degrees Fahrenheit.
Biologists seek to determine why bodies eliminate DNA during hybridization, aiming to grasp the molecular mechanisms behind this process. By studying frogs, they hope to unlock the secrets of genome elimination and its crucial role in species survival.
A large GWAS study identified novel loci associated with asthma susceptibility, including the gene IL1RL1 and HLA-DQA1, in four major ethnic groups. The study suggests unique biological pathways contribute to asthma susceptibility across different ethnicities.
Researchers developed a new time scale using microfossils, doubling the resolution of published GoM time scales. The BP GNATTS provides valuable aid in seismic correlations, detecting unconformities, sediment redeposition, and faults.
Researchers at Tokyo University of Science have discovered a demethylase enzyme that primes gene expression in plants, allowing them to regenerate tissues. This breakthrough could lead to faster and more efficient food production, helping to address global hunger.
A recent study by Georgetown University Medical Center found that only a quarter of PCORI-funded trials between 2015-2018 examined primary care, while specialty care received the majority funding. The study's authors argue that this is wasteful, as most healthcare is accessed within primary care settings.