A new study has identified NSD2 as a fundamental factor in early stages of prostate cancer development, found to alter androgen receptor function leading to rapid cell division and growth. The study may suggest a new way to therapeutically target prostate cancer by targeting the epigenetic component NSD2.
A recent study found that US states with severe abortion restrictions lack comprehensive public infrastructure to support access to reproductive health care and family social services. These states also have limited access to Medicaid insurance and higher rates of uninsured women, exacerbating the lack of medical and social support for...
A study found that island-dwelling animals have slower metabolisms and produce offspring later, making them more susceptible to extinction. This adaptation helps them thrive in pristine environments but also makes them vulnerable to human activities.
Researchers from Japan have discovered that Exportin-5 interacts with a broader spectrum of RNAs, including tRNAs, miRNAs, lncRNAs, and specific mRNAs. This study sheds light on the unique roles of Exp5 in RNA export within Drosophila cells.
The integration of 5G technology with BeiDou Navigation Satellite System boosts RTK positioning accuracy, reducing errors and enhancing success rates in urban areas. This approach tackles common challenges like signal blockages and visibility issues, paving the way for more reliable urban navigation solutions.
A new study found that hospital-admitted patients with sickle cell disease who received Lactated Ringer’s solution had shorter hospital lengths of stay, fewer readmissions, and less pain control medication compared to those who received normal saline. This shift in practice may improve patient outcomes and lower healthcare costs.
Evan Lowder and Chelsea Foudray are conducting a study to assess MOUD provision in the Fairfax County Adult Detention Center, with funding from Fairfax County and the Virginia Opioid Abatement Authority. The study aims to inform best practices for initiating individuals into medication-assisted treatment upon release from jail.
Children's Hospital of Philadelphia researchers have reported encouraging evidence of an effective new gene therapy to treat multiple sulfatase deficiency. The ex vivo gene therapy improved sulfatase production and reduced symptoms associated with the disease in preclinical models.
A recent study by OHSU researchers reveals that the US has a higher rate of firearm deaths compared to other countries with similar sociodemographic profiles. The study found that despite comparable mental health disorder rates, US firearm death rates are 20 times greater than those in other countries.
A new study from the University of Notre Dame finds that Big Tech privacy policies can decrease consumer engagement and satisfaction with ads, leading to reduced performance and revenue. The study explores how data minimization and other policies affect ad variety and consumer behavior.
New vaccines are being explored as a promising approach to treating glioblastoma, a highly lethal brain cancer with limited treatment options. These vaccines have been generally well-tolerated and have shown promise in improving survival rates for GBM patients.
A new study found that RSV vaccination programs targeting older adults with underlying health conditions are more likely to be cost-effective than general age-based strategies. Vaccinating people aged 70 years and older with chronic medical conditions is likely to be cost-effective based on commonly used cost-effectiveness thresholds.
A new MXene-based Matthew membrane exhibits high K+-sieving performance with a K+/Na+ selectivity of up to about 9. The excellent performance is attributed to the recognition effect in the RL and fast transport of hydrated K+ through the EL.
A new robotic leg powered by artificial muscles can walk, jump, and detect obstacles without complex sensors. Its ability to lift its own weight explosively enables high jumps and fast movements.
Yotam Gingold's NSF-funded project focuses on developing in-air 3D drawing tools, sonification techniques, and verbal 3D editing tools, enabling superhuman abilities in digital shape design and perception.
Researchers developed an AI model using 25 seconds of a person's voice to detect type 2 diabetes, distinguishing between individuals with high accuracy. The model showed strong performance, especially in females aged 60 or older and those with hypertension, aligning with the American Diabetes Association risk score.
Researchers at NIST have developed a new method to measure biomolecules in live cells using infrared light, removing water's obscuring effects. This allows for the determination of key biomolecules like proteins and their amounts in cells, speeding up advances in biomanufacturing and cell therapy development.
A study published in Frontiers of Computer Science finds conditions that make a regular balanced random (k,2s)-CNF formula (1,0)-unsatisfiable with high probability. These conditions also apply to random instances of the regular balanced (k-1,2(k-1)s)-SAT problem, providing new challenges for k-SAT problem algorithms.
A new study from Harvard T.H. Chan School of Public Health found that higher exposure to fine particulate air pollution (PM2.5) during infancy is associated with lower economic earnings in adulthood. The association was strongest in the Midwest and South, where an increase in PM2.5 exposure by one microgram per cubic meter was linked t...
Researchers developed Transparent Pressure-Calibratable Interference Electrotactile Actuator (TPIEA) technology to provide consistent virtual haptic experiences. The TPIEA uses platinum nanoparticles to reduce impedance and achieve high transmittance, allowing for precise and varied tactile sensations.
Ravit Helled received the 2024 Paolo Farinella Prize for her work on planetary interiors, proposing a dilute core structure that was later confirmed by mission data. Her research also explores giant planet formation and evolution, with international contributions to NASA and ESA missions.
The multispectral smart window technology regulates visible light while blocking microwave signals, improving energy savings and privacy protection. It outperforms existing technologies in response time, transmittance adjustment range, haze adjustment range, driving voltage, and optical modulation mode.
A new review found that one-third of children with chronic pain also meet the criteria for an anxiety disorder, while one in eight meets the criteria for a depressive disorder. The study suggests that clinicians should consider screening for mental health issues when treating young patients with chronic pain.
A strong belief in own academic ability can help low-income children achieve success despite poverty. Research highlights the importance of addressing emotional and behavioural issues and strategies that foster belief in abilities.
The world's first combined whole eye and face transplant has demonstrated allograft survival, including rejection-free graft survival. The transplanted eye has maintained normal pressure, good blood flow, and some remaining structure and functions in the retina. Researchers are now focused on understanding how to restore sight.
The researchers used advanced techniques like STED microscopy, FRET image spectroscopy, and photobleaching step analysis to measure the number and distribution of CD95 receptors on the membrane. They found that only 15% of receptors need to bind together to activate cell death.
Researchers leverage deep learning networks to recover and enhance compromised metrics in biophotonic image data. This approach improves imaging speed and quality, allowing for high-fidelity all-in-focus images and efficient reconstruction with reduced data acquisition.
A team of researchers from the University of Michigan and Caltech argues that iron was life's primeval metal. They found that early oceans were rich in iron, which is essential for biomolecules to bind to metals. This discovery challenges previous assumptions about the importance of other transition metals like zinc.
Researchers at Columbia University's Mailman School of Public Health used a novel interview method to assess New Yorkers' perceptions on energy insecurity, a public health issue. The study found that energy insecurity is associated with health vulnerabilities and impacts nearly 30% of NYC residents.
Researchers from the University of Virginia Health System found that out-of-body experiences can foster deepened emotional connections with others, leading to increased empathy. This phenomenon, known as ego dissolution, can have a transformative effect on people's ability to experience empathy and connect with others.
Researchers, including WVU astronomer Emmanuel Fonseca, use radio pulsars to detect gravitational waves generated by massive objects. The study will merge data from the Green Bank Telescope and CHIME radio telescope to achieve full coverage of each wave, revealing information about phenomenon and objects in distant galaxies.
A $15 million gift from Sally Ross Soter will support the Go Red for Women Venture Fund, investing in health companies targeting cardiovascular, metabolic, and neurologic solutions for women. The fund aims to close the gap in women's health investment and translate research into better patient care.
Research found that combining neonicotinoids with fungicides significantly increased mortality of bee larvae, while also affecting adult honeybee survival rates and lifespan. The study suggests that solitary wild bees may be more vulnerable to pesticide effects due to their smaller colony size.
A research team at Hiroshima University developed an analytical pipeline to identify unexploited genes associated with Parkinson's disease and oxidative stress. The study revealed two novel candidate genes, NUPR1 and UHRF2, which were absent from current gene-disease associations databases.
A systematic review and meta-analysis of 99 randomized controlled trials found that vitamin D supplementation reduces systolic and diastolic blood pressure, total cholesterol, and fasting blood glucose in various populations. The benefits were most pronounced in non-Western groups, individuals with low baseline vitamin D levels, those ...
A new study found that rural regions in Ontario have significantly higher rates of eating disorders among adolescents and young adults. The researchers suggest that stigma and socio-cultural dynamics may contribute to these disparities, highlighting the need for targeted interventions such as telehealth services.
A recent study reveals that urban underground space (UUS) development can provide substantial carbon-sequestration potential through geothermal energy utilization. The research analyzes China's UUS development over two decades and concludes that long-term operation of metro systems can offer significant carbon-sequestration benefits.
A recent study in Sweden found a significant decline in both melanoma incidence and mortality among individuals aged 30-49. The causes of this downward trend are unclear but may be attributed to increased UV protection, public health campaigns, demographic changes, or advancements in melanoma treatment.
A study found that medical clowns can reduce hospital stays by an average of 43.5 hours and decrease IV antibiotic use for children with pneumonia. The clowns' visits also led to lower respiratory rates, heart rates, and inflammatory markers.
A Dutch study found that night owls are more likely to develop type 2 diabetes due to a disrupted circadian rhythm. Participants with late chronotypes had a 46% higher risk of T2D and increased body fat, including visceral and liver fat.
A new UK study found that patients receiving systemic glucocorticoids are more than twice as likely to develop diabetes. The study, conducted by researchers at the University of Oxford, involved over 451,000 adults and revealed a significant link between steroid treatment and new-onset diabetes.
Researchers identified PRMT5 as a therapeutic vulnerability for overcoming paclitaxel resistance in triple-negative breast cancer. PRMT5 inhibitors disrupt RNA splicing and chromosomal stability, inducing cell apoptosis and triggering cancer death.
Research suggests that eating fruit, oats, and rye in childhood increases the risk of developing type 1 diabetes, but consuming berries may lower this risk. The study followed thousands of children in Finland from birth to age six and found associations between specific foods and an increased or decreased risk of islet autoimmunity.
Researchers found that altitude changes during flights may cause slight increases and decreases in insulin delivery, potentially leading to blood glucose fluctuations. Individuals using insulin pumps should be aware of these effects and consider temporarily disconnecting their pumps before take-off.
A study found that ChatGPT performed better than trainee doctors in assessing complex cases of respiratory disease in areas such as cystic fibrosis and asthma. The chatbot's responses were also scored higher for being human-like, while Google's Bard and Microsoft's Bing performed similarly to or worse than trainees.
A breakthrough technology allows for touchless infrared imaging to monitor changes in pupil size and gaze direction behind closed eyes. This innovation can help identify wakefulness, awareness, and pain in sleep, anesthesia, and intensive care, enabling more accurate clinical decision-making.
Researchers developed a high-density Ir single-atom catalyst on CoGaOOH, achieving low overpotentials and long stability. The neighboring synergetic interaction of high-density single atoms stabilizes OOH intermediates, reducing the reaction energy barrier and improving performance.
A new study found that skin cancer incidence in young adults declined in Sweden around 2015. The decrease in incidence and mortality is attributed to increased awareness of sun protection, reduced access to sunbeds, and changes in lifestyle habits such as spending more time indoors. The study suggests that continued emphasis on sun pro...
Researchers found three new Thylacine species in Australian fossils, including a large species weighing up to 11kg and a highly carnivorous one with elongated cutting blades. These discoveries reveal the diversity of marsupial carnivores during the late Oligocene and challenge previous ideas about Australia's ecosystem.
A recent study presented at the European Respiratory Society Congress found that young vapers performed worse in exercise tests compared to non-vapers and smokers. The research showed that vaping was associated with lower peak exercise capacity, reduced oxygen consumption, and signs of blood vessel dysfunction.
Researchers predicted promising reactions for creating double magic nuclei, such as <sup> 298 </sup> Fl and <sup> 304 </sup> 120. These elements could have unique properties and deepen understanding of atomic forces. The study is a step closer to the 'Island of Stability', where long-lasting superheavy nuclei might exist.
Research found that maintaining good cardiovascular health during the first trimester of pregnancy can partially mitigate the risk of adverse pregnancy outcomes. The study's results suggest that preconception and early pregnancy cardiovascular health counseling is crucial for preventing hypertensive disorders of pregnancy.
Two studies found that long-term exposure to air pollution increases the risk of hospitalization for respiratory conditions, including asthma and COPD. Green spaces may actually increase emergency room visits for respiratory issues when combined with hay fever.
Researchers have developed a semaglutide hydrogel that could reduce diabetes shots to once a month, improving drug adherence and quality of life. The hydrogel's slow release of semaglutide over one month was found to be well-tolerated in laboratory rats with no inflammatory reactions.
A study of 500,000 UK participants found insulin resistance associated with higher risk of 26 conditions, such as sleep disorders and pancreatitis, and lower risk of five diseases, including anaemia and Parkinson's disease. Insulin resistance also linked to increased mortality risk in women.
A new study found that higher BMI is associated with hospitalization for severe bacterial and viral infections. Conversely, mild hyperglycemia was not linked to increased risk of severe infections.
A new library of healthy participants' neuroimaging data has been created to aid in the diagnosis and treatment of traumatic brain injury (TBI). The Normative Neuroimaging Library consists of data from approximately 1900 individuals, providing a comprehensive dataset for clinicians and researchers.
The study predicts light transmission, absorption, and power generation of different PV materials, enabling the selection of optimal materials for agrivoltaics. By carefully tuning the 'colour' of light transmitted through semi-transparent PVs, researchers can enhance crop growth while generating solar power.
Researchers have demonstrated a novel method to increase the density and depth of nitrogen-vacancy centers in type-Ib diamonds through controlled temperature and orientation. This study advances our understanding of diamond materials and opens up new possibilities for cutting-edge scientific and technological applications.
A new study by Imperial College London identifies key trade-offs between effectiveness and scalability in conservation programs. The lessons highlight the importance of balancing program expansion with effective implementation, considering scale-dependent effects on conservation outcomes.