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Science News Archive 2024 - Page 263


Page 263 of 484

Researchers discover potential mole reversal therapy in rare condition

Researchers at Francis Crick Institute develop a new genetic therapy that silences mutated NRAS gene in cells with congenital melanocytic naevus syndrome (CMN), potentially reversing debilitating giant moles. The treatment has shown promising results in mice and could be used to reduce cancer risk in affected children and adults.

SourceThe Francis Crick Institute·JournalJournal of Investigative Dermatology·DateJun 17, 2024

Rapid test of cerebrospinal fluid decreases time to diagnosis for brain tumors

Researchers developed a rapid genotyping test for patients with central nervous system lesions, detecting key mutations associated with brain cancers in samples taken during a lumbar puncture. The test eliminated the need for surgical brain biopsies in seven cases and significantly accelerated time to treatment, from an average of 12 d...

SourceMass General Brigham·JournalBlood·TypeExperimental study·DateJun 17, 2024

Artificial intelligence accurately screens heart failure patients for clinical trial eligibility

Researchers at Mass General Brigham developed a generative AI process that screens patients for clinical trial eligibility with high accuracy and reduced cost. The process, called RECTIFIER, was compared to traditional screening methods and found to be more accurate and cost-effective, with an estimated cost of $0.11 per patient.

SourceMass General Brigham·JournalNEJM AI·TypeComputational simulation/modeling·DateJun 17, 2024

How targeted nutrients can fight cancer

Researchers discovered a new way to effectively treat melanoma using nutrients to reactivate suppressed metabolic pathways in cancer cells. The innovative treatment, involving tyrosine nanomicelles, showed promising results in mice and lab-derived human cells, inhibiting tumour growth and reducing glycolysis.

SourceUniversity of Technology Sydney·JournalNature Nanotechnology·TypeExperimental study·DateJun 17, 2024

International Gemini Observatory and Subaru combine forces to discover first ever pair of merging quasars at cosmic dawn

The International Gemini Observatory and Subaru Telescope have discovered the most distant pair of merging quasars, seen only 900 million years after the Big Bang. The team used follow-up spectroscopy to confirm the nature of the quasar pair and their host galaxies.

SourceAssociation of Universities for Research in Astronomy (AURA)·JournalThe Astrophysical Journal Letters·DateJun 17, 2024

Research into structures of ape hearts provide insight into human evolution

A study comparing human hearts to those of great apes has found that the human heart is more streamlined due to higher demands for blood flow and thermal regulation. This suggests that human hearts may have evolved differently from their primate ancestors in response to unique ecological pressures.

SourceUniversity of British Columbia Okanagan campus·JournalCommunications Biology·TypeObservational study·DateJun 17, 2024

Significant reduction in alcohol consumption among young excessive drinkers: personalized alcohol-reduction advice based on genetic information

A study published in BMC Medicine found that personalized alcohol-reduction advice based on genetic information significantly reduced alcohol consumption among young excessive drinkers. The intervention group showed lower alcohol consumption and AUDIT-C scores compared to the control group, with continued reductions in scores over time.

SourceUniversity of Tsukuba·JournalBMC Medicine·DateJun 17, 2024

Federal study examines care following nonfatal overdose among Medicare beneficiaries; identifies effective interventions and gaps in care

Researchers found that medications for opioid use disorder, naloxone, and behavioral health supports significantly reduce the risk of dying from an overdose. However, significant gaps in care were noted, with only 4% of beneficiaries receiving medications after experiencing a nonfatal overdose.

SourceNIH/National Institute on Drug Abuse·JournalJAMA Internal Medicine·DateJun 17, 2024

Constrained clustering with weak label prior

A new research proposes a constrained Clustering with Weak Label Prior (CWLP) to improve clustering performance by incorporating compound weak label prior information. The approach combines pairwise constraints and cluster ratio information, achieving superior results on benchmark datasets.

SourceHigher Education Press·JournalFrontiers of Computer Science·TypeExperimental study·DateJun 17, 2024

Ensuring ‘pediatric readiness’ in emergency departments costs little and saves lives

A new study finds that pediatric readiness in emergency departments can significantly reduce mortality by up to 76% while requiring a low annual cost of implementation, ranging from $23,775 to $145,521. Hospitals with high pediatric readiness can improve survival rates without breaking the bank.

SourceUniversity of Texas at Austin·JournalJournal of the American College of Emergency Physicians Open·DateJun 17, 2024

Pancreatic cancer’s cellular amnesia

Researchers have discovered that a protein called MED12 plays a critical role in pancreatic cancer's development, particularly in basal-like cells. The study builds on decades of research at Cold Spring Harbor Laboratory, which previously identified the importance of p63 for basal cell formation.

SourceCold Spring Harbor Laboratory·JournalNature Genetics·DateJun 17, 2024

Simplicity versus adaptability: Understanding the balance between habitual and goal-directed behaviors

A new study on learning has provided insights into the balance between habitual and goal-directed behaviors, with implications for AI development. The research suggests that a balance between these two types of behavior is necessary for efficient and adaptable decision-making in AI systems.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeComputational simulation/modeling·DateJun 16, 2024

NIH-funded intervention did not impact opioid-related overdose death rates over evaluation period

The NIH-funded HEALing Communities Study found that a data-driven intervention did not significantly reduce opioid-related overdose deaths, despite engaging communities in evidence-based practices. The study suggests that factors like the COVID-19 pandemic and increasing fentanyl presence may have weakened the impact of the intervention.

SourceNIH/National Institute on Drug Abuse·JournalNew England Journal of Medicine·DateJun 16, 2024

USTC proposes new constraints on exotic spin-spin-velocity-dependent interactions between electron spins

Researchers at USTC have detected two new exotic spin-spin-velocity-dependent interactions using solid-state spin quantum sensors. These findings provide valuable insights into fundamental interactions and could help explain observational facts in cosmology such as dark matter and dark energy.

SourceUniversity of Science and Technology of China·JournalPhysical Review Letters·DateJun 16, 2024

Self-healing mechanisms toward stable photoelectrochemical water splitting

Researchers have introduced new self-healing mechanisms to address the stability challenges in photoelectrochemical (PEC) water splitting. These mechanisms, such as intrinsic and extrinsic self-healing, aim to improve the long-term stability of semiconductor light absorbers, protection layers, and co-catalysts.

Study reveals increasing polarization in climate change coverage between elite and heartland news sources

A study reveals an increasing polarization in climate change coverage between elite and heartland US news sources. National newspapers have expanded their climate desks and significantly increased their coverage, whereas smaller news sources based in the heartland have also increased their coverage but at a much slower rate.

SourceUniversity of California - San Diego·JournalClimatic Change·DateJun 16, 2024