Researchers studied the YB1 protein's cold-shock domain, finding moderate stability under physiological conditions. The domain can interact with multiple nucleic acids, facilitating quick and efficient binding, which may contribute to cancer cell resistance.
A UChicago team has developed innovative materials to create flexible OLED screens that can be used in a variety of applications, including wearables and medical devices. The new materials overcome the challenges of making aluminum stretchable and improve electron mobility.
Professor Owen Guy has received the SEMI Academia Impact Award for his outstanding contributions to semiconductor research, innovation, and industry-academia collaboration in Europe. He is Director of Swansea University's Centre for Nanohealth and a member of its Centre for Integrative Semiconductor Materials.
Researchers at Princeton University developed a diamond-based quantum sensor that uncovers rich new information about magnetic phenomena at the atomic scale. The technique provides key insight into materials like graphene and superconductors.
Researchers discovered that plants respond to compacted soil by thickening their roots and changing their structure, allowing them to penetrate harder. This mechanism is similar to basic engineering principles, such as a pipe's diameter and outer wall strength affecting its ability to resist buckling.
Researchers achieved hydroxyl groups esterification and lignin dissolution through a two-hour pyridine-benzoyl chloride bath. The resulting fibers became photobleaching and stable under accelerated weathering, with a 15-unit ΔE* swing and 96% plunge in tensile strength.
Mayo Clinic researchers have found several previously unknown genetic and cellular processes that occur in lung adenocarcinoma tumors responding well to immunotherapy. The study identified markers that may predict a positive response to immunotherapy, including the presence of senescent tumor cells and loss of the PRKCI gene.
Researchers explore innovative avenues for regenerating functional β-cells using stem cells and pancreatic progenitor cells. The dual approach of activating endogenous progenitors and transplanting externally differentiated cells represents a powerful, scalable strategy for T1D management.
Researchers developed soft robots inspired by manta rays, utilizing magnetic fields to move, recharge power supply, and perform tasks autonomously. The magnets stabilize electrochemical reactions in flexible batteries, enhancing performance and efficiency.
Researchers have discovered nanodomains within biomolecular condensates that aggregate FUS protein, a key regulator of cellular RNA metabolism. The movement of these nanodomain clusters can be slowed down or accelerated by applying drugs used to treat ALS, offering potential new avenues for slowing neurodegenerative disease.
A study of almost 258,000 children in Scotland found that lockdown measures during the Covid-19 pandemic were associated with an increase in developmental concerns, including speech and language skills, physical movement, and emotional growth. The proportion of children with at least one developmental concern increased by up to 6.6 per...
Researchers developed a non-invasive spinal stimulation system that bypasses the lesion site and strengthens preserved spinal circuits. This approach enables paraplegic patients to regain bilateral stepping control and improve step length and cadence.
A study by University of Wisconsin-Madison researchers has identified a previously unknown gravitropism pathway in plants, which helps them orient their growth direction. This new pathway, controlled by the SLQ1 gene, works independently of the LAZY genes and may provide a backup mechanism for detecting gravity.
The study highlights the importance of seamount conservation for Cape Verde's marine ecosystem, biodiversity and socio-economic development. The research emphasizes the need for integrated conservation strategies that consider ocean waters and human uses.
A reconfigurable omnidirectional triboelectric whisker sensor array (RO-TWSA) enables multidirectional force sensing, portable deployment, and adaptive interaction across complex environments. The system combines an untethered hydro-sealing suction mechanism with a high-sensitivity MXene-enhanced triboelectric whisker structure.
A new study reveals that persistent organic pollutants accumulate in tissues of sheep and their lambs from birth, transferring to the developing fetus. Concentrations of POPs in lamb tissues averaged 30–103% of those measured in the mothers.
The study examines the global epidemiology of amyotrophic lateral sclerosis (ALS) and other motor neuron diseases (MNDs), revealing a rising global burden with significant variations across regions. Regional factors contribute to these diseases, emphasizing the need for optimized medical resources and further research.
A new concept called Weather Commons proposes a democratic approach to weather control, emphasizing collective stewardship and cooperation between local communities. The framework aims to provide a platform for civic dialogue on the role of technology in addressing extreme weather intensification.
A study found that hepatitis C treatment with direct-acting antivirals (DAAs) improves immune function in individuals co-infected with HIV and HCV, even in those with advanced liver disease. The treatment resulted in significant declines in inflammation and liver damage markers.
Researchers have identified a key mechanism behind statin-induced muscle damage, paving the way for new statins with reduced side effects. By understanding how statins interact with muscle proteins, scientists can design safer alternatives that preserve cholesterol-lowering benefits.
Researchers developed a scalable solution using a perforated Cu current collector to induce a regularly arranged micropore structure, enhancing ion diffusion and mechanical stability in SiOx/Artificial Graphite electrodes. This design improvement leads to improved electrochemical performance for fast-charging and long-life batteries.
Researchers have discovered that a mitochondrial mutation can remodel immune cell function and inflammatory signalling, leading to whole-body issues in animal models. This finding offers a plausible hypothesis for why individuals with these disorders often experience problems with multiple organs and repeated infections.
The POSTECH team proposes two innovative strategies using nanoimprint lithography to address the limitations of traditional metasurface manufacturing. The hybrid material method and particle-embedded resin method enable high-performance metasurfaces with optical efficiencies comparable to electron beam lithography, making large-scale m...
A new evidence brief highlights the need for a One Health approach in research into zoonotic disease risks globally. The study found significant knowledge gaps in understanding factors influencing zoonotic disease occurrence in agrifood systems, particularly in low- and middle-income countries.
Researchers at SwRI have developed a reliable testing methodology to study stochastic pre-ignition in hydrogen-fueled internal combustion engines. The methodology provides insight into lubricant-initiated pre-ignition events and supports further work on mitigation strategies and commercial lubricants.
A randomized clinical trial conducted at UCLA Health found that AI scribe tools reduced physician documentation time by 9.5% and improved burnout scores. While the technology showed promise, it also generated clinically significant inaccuracies and required active physician oversight.
In a study by SWPS University, researchers found that children interact with polite robots almost always respond politely. Younger children and girls are more likely to anthropomorphise the robot, suggesting social cues in interactions between children and robots are crucial for positive learning outcomes.
Researchers propose technology using multimodal information from LiDAR, GPS, IMU, and thermal camera to reconstruct transmission line geometric profile and estimate sag. The approach can predict how the shape of the TL would change under extreme thermal conditions.
A team of researchers has developed a two-in-one nanostructured SERS sensor integrated into a stretchable and antimicrobial wrapper that monitors food directly on the surface and actively preserves it. The proposed technology enables real-time, non-destructive detection of nutritional components and tracks spoilage progression over time.
Studies have confirmed that liquid droplets formed by ubiquilin-2 (UBQLN2) facilitate the aggregation and fibril formation of α-synuclein protein. Researchers also discovered a compound that interacts with UBQLN2, preventing its self-association and liquid droplet formation, which may lead to new treatments for neurodegenerative diseases.
Repeated head impacts in professional boxers and mixed martial artists can lead to cognitive decline and neurodegenerative disorders. The glymphatic system, responsible for clearing waste from the brain, is compromised in fighters with higher numbers of knockouts.
A novel mRNA-based therapy has been shown to slow bacterial growth, strengthen immune cell activity, and reduce lung tissue damage in models of multidrug-resistant pneumonia. The therapy works by giving the body a special protein that directly breaks down harmful bacteria and recruits immune cells to help clear them out.
A large-scale laboratory screening identified 168 chemicals toxic to human-made gut bacteria. Washing fruit and veggies before consumption may help avoid exposure to these pollutants. Researchers developed a machine learning model to predict chemical harm, emphasizing the need for safer industrial practices.
Researchers at the University of Oxford have discovered an approach to electrically switch organic LEDs to emit either left- or right-handed circularly polarized light. This could lead to new applications in displays, secure communication systems, and quantum technologies.
Researchers have identified regions of the human genome particularly prone to mutations, which can be inherited by future generations. The mutated stretches of DNA are located at the start point of genes and are more susceptible to errors during cell division.
A new AI image-only model has been shown to provide stronger and more precise risk stratification for five-year breast cancer prediction than traditional breast density assessment. The model was trained on 421,499 mammograms and showed a fourfold higher cancer incidence in high-risk women compared to those with average risk.
A new deep-learning tool can rapidly identify wild and farmed salmon by analyzing fish scales, with 95% accuracy. This technology has the potential to mitigate the ecological impact of escaped farmed salmon on wild populations.
A new study of over 3,000 women aged 60+ found that using sex toys during masturbation leads to a higher frequency of orgasm. The study suggests that older women could benefit from receiving more information on sex toy use and orgasm promotion from healthcare professionals.
Researchers have identified a distinct type of frailty in younger people driven by cardiovascular and metabolic illnesses, leading to poor outcomes and premature death. The study calls for routine frailty assessments in all heart attack patients, regardless of age.
A Brown-led study of Rhode Island's Eat Well, Be Well Incentive Program found modest increases in fruit and vegetable consumption among participants, but highlights the need for better awareness and access to the program. The program aims to encourage healthy eating by giving SNAP recipients $0.50 back for every $1 spent on fresh produce.
The French-Singapore quantum ecosystems have signed three new research agreements to strengthen their collaboration in quantum computing, energy-efficient technologies and photonics. This will advance quantum research and move discoveries closer to real-world applications.
A new study found that nearly 1 in 5 mobile reading apps lack educational value, with many failing to provide explicit teaching or structured approaches. The researchers are calling for greater regulation and certification of app quality to ensure children engage with tools that support their learning.
A six-month randomized controlled trial found that a single post-meal biomarker, SPARC-1H, predicts who will benefit most from adopting a Mediterranean diet. Individuals with lower baseline SPARC levels experienced greater improvements in insulin resistance and glucose metabolism after six months of dietary adherence.
A University of Adelaide study found that promotional cues, product placement, and pricing interventions can empower people experiencing food insecurity to select more nutritious foods. The intervention led to an increase in turnover of healthy options and a decline in discretionary snacks.
Rocatinlimab shows durable improvements in skin clearance, itch, and quality of life by targeting OX40 immune receptor in patients with moderate-to-severe atopic dermatitis. The treatment led to significant reductions in eczema severity, itch, pain, and sleep disturbances.
A new scholarship has been established at NUS Medicine to support students in the Master of Clinical Mental Health and Psychotherapy programme, enabling them to train as mental health professionals. The S$3 million gift from the Elaine and Eduardo Saverin Foundation will cover tuition fees and provide a monthly stipend for 18 months.
Researchers develop soft fiber-like pumps powered by ambient energy to drive the next generation of robots and wearable devices. The innovation enables robots that operate autonomously and wearable devices that provide comfort without cumbersome batteries.
Researchers developed a new robot self-modeling approach using part-based Neural Radiance Fields, eliminating the need for depth sensors and human annotation. The system enables robots to build dynamic 3D models of themselves, accelerating the deployment of autonomous machines in unpredictable environments.
Researchers have found that individuals with insomnia fail to downregulate mental activity at night, resulting in a blunted and delayed disengagement from goal-directed thought and emotional involvement. This study suggests that tailored approaches addressing circadian and cognitive factors could offer a solution for insomniacs.
A study published by Lund University suggests that tattoos could be a risk factor for melanoma. Researchers found a 29% increased relative risk among tattooed individuals compared to non-tattooed individuals. The link may be due to the immune system's response to tattoo ink, which can lead to exposure to potential carcinogens.
Researchers found that tumor cells with lost GPX4 adapt metabolically to escape ferroptosis, reprogram triacylglycerol metabolism, and impair CD8+ T cell function. Inhibition of triacylglycerol synthesis sensitizes tumor cells to ferroptosis, restoring CD8+ T cell function.
A team of astronomers from ICRAR has released new data showing that a galaxy's 'neighbourhood' plays a major role in its evolution over time. The study found that where a galaxy lives strongly influences its shape, size and growth rate in the distant Universe.
A research team identified a key function of the intestinal nervous system in controlling the intestinal barrier's composition and stability. The study suggests that the 'gut brain' acts as a central hub for health, immunity, and potentially conditions like allergies, and may be influenced by diet.
Researchers found that famous singers in the UK/Europe and North America died an average of 4 years earlier than those not in the spotlight. The effects of fame are comparable to other known health risks, such as smoking, which confers a heightened risk of death.
A scalable approach to designing and fabricating wireless electronic systems that can adapt to 3D surfaces has been developed by Penn State researchers. This method uses liquid metal patterns printed onto heat-shrinkable polymer substrates, enabling the creation of customizable smart devices.
Drinking 3-4 cups of coffee a day may slow the biological ageing of people with severe mental illness by lengthening their telomeres, equivalent to 5 extra biological years. However, no such effects were observed beyond this daily amount.
Scientists have developed a new material that converts motion into electricity with greater efficiency than traditional lead-based ceramics but without using toxic lead. The material, based on bismuth iodide, has potential applications in a wide range of innovative devices.
The University of Tennessee has six faculty members recognized as among the world's most highly cited researchers, including Sheng Dai and Xianzhi Meng. Their work focuses on developing advanced materials for energy-related applications, improving biomass use for renewable energy, and innovating microscopy techniques.
The American Academy of Neurology (AAN) has opened press registration for the 78th Annual Meeting, taking place April 18-22 in Chicago and live online. The event will feature over 3,500 abstracts covering 25 neurology topics, as well as late-breaking research and educational courses.
A new study by Montana State University scientists explores elevation-dependent changes in climate, including variations in precipitation, surface albedo, and air temperature trends across mountain ranges globally. The findings have direct implications for water availability and use in regions like Montana.