Researchers at Aarhus University have developed an artificial virus-like DNA needle that can deliver molecules directly into cells. The technique uses DNA origami to assemble the needle and deliver its payload, potentially solving a major issue with many therapies being trapped inside cells.
Insilico Medicine will present four novel cancer inhibitors discovered via its Pharma.AI platform, targeting KRAS and Cbl-b pathways. ISM6166 and ISM3830 demonstrate robust anti-tumor activity against solid tumors with KRAS alterations and restored innate and adaptive immunity, respectively.
The research presents a comprehensive taxonomy of prompt engineering techniques, categorizing them by underlying principles and outlining a pipeline for designing effective prompts. This enables developers to optimize prompts for various applications, from creative content generation to high-stakes decision-making.
Researchers at KIT analyzed scientific papers using AI to identify emerging trends and relationships. The study suggests that large language models and machine learning can help reveal new avenues of research and opportunities for interdisciplinary cooperation.
A new UBC study found that global aquaculture production is increasingly relying on less beneficial species for food security, climate mitigation, and biodiversity. The industry's shift towards finfish has lower sustainability potential, while earlier systems like seaweed and shellfish had higher sustainability.
Researchers at Charité develop test to determine circadian rhythm using hair roots, revealing genetic and lifestyle factors influencing internal clock. The new method shows promise for tailoring therapies to individual rhythms, potentially improving treatment outcomes.
Researchers propose a novel approach to dataset acquisition in spatial data marketplaces, optimizing spatial coverage and connectivity under budget constraints. The proposed Budgeted Maximum Coverage with Connectivity Constraint (BMCC) algorithm achieves up to 68% larger spatial coverage with 89% speedups compared to existing methods.
Researchers propose adaptive protocol for GHZ states, combining short and long measurements to achieve high precision while maintaining dynamic range. This approach enables dual Heisenberg-limited scaling, surpassing older methods, and proves more resilient to noise and dephasing.
Research reveals a potential connection between gut microbiota and atopic diseases such as bronchial asthma and food allergies. Small intestinal bacterial overgrowth (SIBO) may contribute to the worsening of symptoms in these conditions. Further studies are needed to confirm this association.
Researchers challenge long-held assumptions about vegetation patterns in dryland ecosystems, finding that such patterns can actually indicate reduced ecosystem resilience. The new theoretical framework takes into account spatial constraints and environmental heterogeneities, revealing that ecosystem stability depends on specific enviro...
In this randomized clinical trial, mirtazapine effectively reduced methamphetamine use in adults with methamphetamine use disorder. The study's findings have important implications for the treatment of this condition, which currently lacks approved pharmacotherapies.
Scientists at the University of Manchester discovered a rare mathematical process underlying the formation of corrugations in soda cans. The sequence of buckles follows homoclinic snaking, a phenomenon where bumps or ripples appear one by one in a precise order.
A team of researchers discovered that inflammation in multiple sclerosis causes DNA damage to neurons essential for higher thinking and cognition. This finding provides a new direction for the field and highlights the importance of protecting grey matter neurons from damage.
Mohamed Abou-el-Enein, a USC physician-scientist, has received the Outstanding New Investigator Award and Best of Molecular Therapy Award from the American Society of Gene + Cell Therapy. His work focuses on translating scientific discoveries into clinical applications, with a particular emphasis on cell therapies.
A new study reveals that blocking the aryl hydrocarbon receptor (AHR) helps neurons regrow damaged axons and recover motor and sensory function. AHR acts as a key regulator that determines how neurons respond after injury, slowing down axon growth.
The review highlights LRRK2's diverse cellular functions and pathogenic mechanisms in various diseases, including Parkinson's disease and inflammatory disorders. Therapeutic strategies targeting LRRK2, such as kinase inhibitors and emerging approaches like PROTACs and gene therapy, show promise for correcting cellular imbalances and re...
A collaborative effort involving 865 researchers has published new empirical evidence on reproducibility, robustness, and replicability of social and behavioral sciences research. The SCORE program's outcomes will contribute to strengthening how research is interpreted and communicated.
Dr Amy Shirong Lu joins JMIR Serious Games as Editor-in-Chief with extensive research on digital health technologies and their impact on physical activity and cognitive health.
MDPI has opened its first US office in Philadelphia, serving as a central hub for scholarly engagement across the country. The new office will provide regional support to US scholars, manage scholar visits, and represent MDPI at conferences throughout the US.
A multi-site study found that AI scribes reduced electronic health record usage by 3% and clinical documentation time by 10%, with primary care physicians experiencing the greatest reductions. The technology also showed a slight increase in productivity, measured as 0.5 additional patient visits per week.
Current AI systems lack internal embodiment, a property that humans take for granted, which can lead to performance and behavior limitations. Researchers propose a dual-embodiment framework to guide future research in building safer and more aligned AI models.
Researchers at NIH have identified a novel opioid compound that shows potential as a therapy for both pain and opioid use disorder. The new drug, called DFNZ, has high pain-relieving effects without causing respiratory depression or addiction.
A 500-million-year-old fossil reveals the earliest known chelicerate with a claw, pushing back the evolutionary history of chelicerates by 20 million years. This discovery sheds light on the assembly of the chelicerate body plan and their early ecological context.
Between 2021 and 2024, government organizations accounted for around one-tenth of the estimated $336 million spent on advertising to news websites publishing health misinformation. Pharmaceutical companies also made notable contributions.
The adoption of AI-powered scribes was associated with modest decreases in total electronic health record time and documentation time. This is due to automation of routine tasks allowing clinicians more time for high-value patient care.
A new catalytic strategy using hydroxyl-induced cobalt oxide enables efficient conversion of syngas to light olefins through Fischer-Tropsch synthesis. The catalyst achieved high CO conversion and light olefin selectivity, with carbon utilization efficiency reaching up to 13%.
This study introduces a novel method that couples buoyancy-driven convection with localized acoustic microstreaming to enhance macroscopic mixing and microscopic mass transfer. The results show significant advantages in high-viscosity media, including increased effective coverage area and mean flow velocity amplitude.
A new UAV perching system utilizes a magnetic tensegrity-enabled robotic gripper with an adaptive energy barrier, enabling low-power and stable aerial operations. The system demonstrates rapid closure and high holding capability, with improved performance on rough surfaces.
The American Society of Hematology has published clinical practice guidelines for diagnosing and managing severe acquired aplastic anemia, a rare and life-threatening bone marrow failure disorder. The guidelines highlight the importance of shared decision-making between patients and providers, as well as the need for additional researc...
A new study found that popular vitamin B3 derivatives, commonly taken by cancer patients to manage chemotherapy side effects, can actually make cancer cells more resistant to treatment. This means that supplements like NMN, NR, and NAM may be undermining treatment in critical ways.
A recent FAU study found that individuals with prior criminal behavior, low self-control, and favorable attitudes toward deviance are more likely to access the dark web. The research highlights the importance of understanding who accesses this platform and why, particularly for those intending to engage in illicit activities.
A recent study reveals that Alaskan permafrost is thawing rapidly, leading to increased runoff, carbon releases, and altered coastal ecosystems. The research focused on a Wisconsin-sized area of Alaska's North Slope, simulating daily river flows and coastal exports over 44 years.
A review by an international team of researchers highlights that air monitoring is essential for global public health strategies, as airborne antibiotic resistance genes can spread silently between humans, animals, and the environment.
The NCCN 2026 Annual Conference emphasized the need for holistic care for adolescents and young adults with cancer, highlighting unique challenges and the importance of supportive services. The conference also addressed global cancer care realities and future strategies, emphasizing the need for collaboration and investment to address ...
A team of researchers found that Gli2 and Gli3 function synergistically to regulate tooth root morphogenesis. Their study revealed a critical interaction between HH signaling and TGF-β signaling, which is essential for normal root development.
A study published in BMC Public Health found an association between antibiotic use and maternal mental health during pregnancy. Researchers analyzed data from over 94,000 pregnant women and discovered a stepwise pattern of psychological distress linked to increasing antibiotic exposure. The findings suggest that avoiding unnecessary an...
A new survey by Autism BrainNet reveals a significant disconnect between Americans' strong support for autism research and their limited understanding of postmortem brain donation. The survey found that 70% of respondents had never heard of brain donation, despite 92% agreeing its importance in advancing research.
A study published in Nature Health reveals a strong link between pesticide exposure and the risk of developing certain cancers. The research shows that pesticide exposure increases the risk of cancer by 150% in areas with high levels of pollution, and highlights early biological effects before cancer develops.
A new study suggests Saturn's magnetic field is asymmetrical, with cusps located most often between 13:00 and 15:00. The researchers believe rapid spin and heavy plasma from Enceladus drag the field lines to the right.
A team from UNIGE has created a molecular system that distinguishes and neutralises cancer cells with unprecedented precision, paving the way for autonomous, self-regulating drugs. The technology uses synthetic DNA strands to deliver potent drugs only where they are needed, reducing damage to healthy tissue.
A new study from Umea University reveals that adult children's unemployment is strongly associated with the depression risk of older parents in India. The research, based on extensive data from the Longitudinal Ageing Survey of India, shows a clear link between child employment and parental mental health.
A KIST-IAE joint research team developed a catalyst technology that maximizes the surface activity of 2D nanomaterial tungsten diselenide, enhancing the performance and durability of lithium-air batteries. The innovation converted the entire basal plane into an active catalytic site, significantly improving reaction rates.
Emissions of nitrogen oxides (NOx) and carbon monoxide (CO) in Salt Lake City have declined significantly over the past two decades, driven by improved vehicle technology and emission standards. Meanwhile, levels of carbon dioxide (CO2), a major contributor to climate change, have remained relatively steady.
Researchers developed a method to predict how metal strain influences adsorption energies and reaction barriers, enabling the design of strain-engineered catalysts with desired properties. They found that electronegativity is closely correlated with the energetic response to lattice strain.
Hong Kong Climate Week 2026 aims to harness the city's strengths as an international financial centre and global connectivity hub. The event focuses on bridging global consensus and local implementation, highlighting the need for adaptation and innovation in addressing climate change.
The 'Action for Earth' Summit brings together global leaders to examine policy pathways, frontier research, and actionable strategies for climate adaptation. The summit features keynote sessions on priority policies and frontier research, as well as a roundtable discussion on accelerating cross-border climate action.
Researchers at HKU have developed an innovative method for fabricating scalable, free-standing diamond membranes with exceptional efficiency and scalability. The breakthrough enables the production of ultra-flat and flexible diamond films crucial for next-generation electronic and photonic devices.
The Hong Kong Housing Bureau and the University of Hong Kong have signed an MOU to leverage research prowess in advancing construction technologies for public housing projects. The partnership aims to bring world-class innovations to local construction practices, prioritizing quality, sustainability, and efficiency.
Scientists developed a scalable ultrastrong bamboo strip through homogeneous fusion, achieving 942 MPa tensile strength and 32.1 GPa Young's modulus. The material demonstrates exceptional durability, biodegradability, and practical scalability for various industries.
Researchers develop a comprehensive framework for parallel single-pixel imaging, enabling accurate separation and localization of complex illumination components. The proposed model shows advantages in mixed-scene reconstruction and significantly outperforms conventional methods in low signal-to-noise ratio environments.
A commentary resolves a century-old mystery of arboviral transmission by identifying molecular constraints that govern systemic viral dissemination in mosquitoes. The study reveals that flaviviruses use extracellular vesicles to transmit and are bound by valosin-containing protein, providing targets for prevention and control.
Researchers have demonstrated a world-leading classical simulation of iterative quantum phase estimation circuits for quantum chemistry on up to 1,024 GPUs, expanding the scale of molecular systems available for the development and validation of quantum algorithms. This achievement supports progress toward industrial applications in dr...
The Centre will address bottleneck challenges in advanced battery materials and electric-enabled technology for energy storage and green conversion. Collaborations with renowned institutions will drive innovation and accelerate translation of research outcomes into real-world impact.
A research team led by Prof. Su Hui and Prof. Wang Cen found that tropical Pacific climate shifts are driving the rapid loss of Arctic sea ice since 2000. The study reveals that ENSO phase transitions are amplifying autumn sea ice loss in the Laptev-East Siberian Sea.
A comprehensive study decodes structure-function relationships governing surfactant-mediated enzyme protection, revealing a competitive stabilization mechanism. The research identifies key factors influencing mitigation efficacy, including hydrophobicity and hydrogen bonding capacity, and provides predictive power for designing more ef...
The University of Hong Kong's education subject has been ranked 5th globally and 1st in Asia in the latest QS World University Rankings by Subject 2026. The Faculty of Education attributes its success to research-led initiatives, strong partnerships, and educating future educators.
Microalgae are transformed into functionalized composite bioproducts for precision diagnosis, targeted therapy, and integrated theranostics. They offer exceptional biological properties for biomedical engineering, including molecular loading, active movement, and intense autofluorescence for imaging applications.
Researchers have uncovered hidden features in X-ray signals, fundamentally changing how scientists interpret them across multiple fields. The discovery enables more precise measurements and a deeper understanding of materials, from battery materials to biological proteins.
The conference will feature keynote dialogues, fireside chats, and panel discussions on key themes such as AI and education, law and regulation, public governance, and global cooperation. Distinguished participants include senior representatives from international organisations and public policy institutions.
HKU excels in key disciplines, including Dentistry (2nd) and Education & Training (5th), while Data Science and Artificial Intelligence rank 18th worldwide. The University will establish an AI Hub to maximize the potential of 'AI + X' across disciplines.