A recent study has revealed that brain tumors use a protein called MIF to reprogram immune cells, such as macrophages and microglia, to drive tumor growth. The researchers have identified a drug, ibudilast, which can block this process, slowing metastasis in animal models and fresh patient samples.
The UJI's GRAPE group proposes a paradigm shift in language teaching with a computer tool that analyzes verbal and visual elements. The software, GRAPE-MARS, enables fast labeling of video files and incorporates AI tools for efficient analysis.
Researchers developed an AI model to create highly photorealistic 3D reconstructions of ground-level damage after earthquakes. The LoRA-Enhanced Ground-view Generation diffusion model can recognize complex visual patterns and predict where structures may be damaged, even in densely populated urban areas.
A study found high concentrations of polycyclic aromatic hydrocarbons (PAHs) and leachable metals in recycled tire rubber granules, particularly in finer fractions. The smallest particles showed stronger toxicity to soil organisms, plants, and aquatic bacteria, highlighting potential environmental and health concerns.
A recent study by Pompeu Fabra University reveals that socioeconomic conditions significantly impact young people's ability to detect algorithmically personalized advertising. The study finds that lower socioeconomic status is linked to decreased critical capacity, exacerbating structural inequalities.
Researchers reveal that urban tributaries intensify water and sediment pollution risks in the Yangtze River, particularly during wet seasons. Phthalate acid esters (PAEs) are present in high levels in tributary waters and sediments, posing ecological and health risks.
The Brain Health Collaboratory aims to accelerate the discovery, validation, and delivery of non-invasive neuroprotective therapies for cognitive decline and Alzheimer's disease. Cognito Therapeutics' Spectris technology platform will be combined with Ochsner's clinical network to explore new approaches to brain health care delivery.
A new study found that immune signatures in blood samples can help identify poor responders to cancer treatment. The research, conducted on pet dogs with diffuse large B cell lymphoma, identified specific genes associated with long-term survival and poorer outcomes.
The Re-Analysis of Water for Society (RAWS) project seeks to create a detailed daily record of the world's freshwater systems spanning 60 years. By combining advanced water modeling with artificial intelligence and integrated global datasets, RAWS aims to provide a clearer picture of how water systems have changed over time.
Levels of toxic PFAS in New Jersey's public water systems dropped by as much as 55% after the state set limits. The study analyzed 12,000 monitoring results and found significant declines in PFOA and PFNA levels, with a notable drop in contaminated wells before regulations were implemented.
A new BGU study examines the emotional labor of teachers during wartime, revealing that those who fake emotions are at higher risk of psychological collapse. The research emphasizes the importance of fostering internal motivation and clear educational identities to mitigate teacher attrition.
A new study found that biodegradable plastics can trigger intense but short-lived spikes in antibiotic resistance genes and pathogens as they degrade. Conventional plastics, on the other hand, consistently exhibit higher levels of antibiotic resistance and genetic transfer potential, posing a chronic long-term threat to public health.
A study by the Catholic University of Milan found that taking a fake supplement for 3 weeks can lead to significant improvements in physical performance and cognitive function, especially when participants are aware they're taking a placebo. The open-label placebo group showed lower levels of perceived stress and improved short-term me...
The ATS 2026 International Conference will feature the ATS AI Lab Exposition Space, highlighting advancements in AI in healthcare. Keynote speakers Robert M. Wachter and Laurah Turner will discuss AI's impact on medical education and its future.
A new study reveals that climate change is accelerating the rate of sublimation, causing less ice to melt into water that feeds reservoirs and rivers. The research found evidence of increasing sublimation rates from 6,000 to 600 years ago, with implications for future snow droughts.
Rising temperatures in the Amazon are threatening dung beetle populations, with diversity and abundance highest at intermediate altitudes. The study found that temperature is the key factor limiting dung beetle diversity and abundance, while other conditions play a minor role.
A new study reveals that turtles surviving the Cretaceous-Paleogene extinction event largely relied on a diet of hard-shelled organisms. This ecological adaptation allowed them to thrive in environments where other species struggled to survive, with dietary specialization being a key factor in their survival.
Researchers sequenced the complete genome of Pseudocercospora cladosporioides, identifying key genes involved in degrading the olive tree's cell wall and inhibiting its resistance mechanisms. This breakthrough will aid in breeding resistant varieties and understanding fungus-olive tree interactions.
Researchers modelled the structure of the magnetic field and cosmic radiation throughout the Laschamps excursion. The results show that cosmic radiation penetrated the atmosphere at record levels, with regions where it could freely enter irradiating a major fraction of the Earth's atmosphere.
A novel dual-crystal-phase manganese dioxide (MnO₂) cathode has been developed to improve the performance and stability of aqueous zinc-ion batteries. The cathode offers high capacity, rapid charging capabilities, and exceptional longevity due to its unique interface between two different crystal structures.
A study in mice reveals that chronic intestinal inflammation can lead to epigenetic 'memories' that promote colon cancer. Researchers found that even seemingly healed gut tissues retain molecular scars from earlier inflammation, making it easier for cancer to take hold.
Exosome-based therapies harness the power of microRNAs to activate hair follicle stem cells, promoting hair growth. Key findings include the identification of pro-anagen and inhibitory microRNAs that regulate Wnt/β-catenin, Shh, and HIF-1α pathways.
Researchers created a pioneering database to map neocortical development across species using multiomic data from 188 studies. They discovered that humans take longer than mice to reach full molecular maturity, and gene regulation plays a key role in brain disorders.
A systematic review of experimental studies found exergames to be associated with better mood outcomes, including reductions in tension and depressive symptoms. The evidence base remains small and heterogeneous, but the study calls for longer-term interventions and larger samples to determine the durability of benefits.
Researchers from University of Jyväskylä and Aalto University develop area-selective atomic/molecular layer deposition of europium-organic thin films on graphene and other 2D materials. The method enables precise construction of films with different shapes, one molecule-thick layer at a time.
A new study by UFZ researchers warns that extreme global climate outcomes are possible even at moderate levels of global warming, such as 2°C. Sector-specific drivers like precipitation extremes and droughts can lead to severe impacts in vulnerable regions. The study highlights the need for ambitious climate mitigation measures to limi...
Researchers develop a novel 'steric hindrance' strategy to boost the performance of single-atom catalysts in oxygen reduction reactions. The approach uses metalloporphyrins with bulky groups to prevent atomic agglomeration and ensure high efficiency.
Researchers found that dogs were domesticated from grey wolves more than 14,000 years ago and contributed substantially to the genetics of modern dogs. The study analyzed DNA from 216 ancient remains, including a 14,200-year-old dog, confirming that European dogs share ancestry with Asian dogs.
A new study finds caregivers of Alzheimer's patients face significant unmet needs, including limited knowledge about the disease, high psychological stress, and lack of community support. Caregivers need practical skills training and mental health support to improve resilience.
This study introduces a breakthrough approach to regulate mixed-valence states in perovskite electrodes for VRFB, offering valuable insights into high-performance metal-based electrocatalysts. The findings highlight the importance of interdisciplinary research in materials science and electrochemistry.
A team of researchers found a mechanism that taps into normal brain development to drive tumor growth in pediatric supratentorial ependymoma. The ZR fusion protein interacts with genetic material, altering expression and creating a heterogeneous tumor.
A research team led by LEE Doyun and KIM Yee-Joon found that the primary visual cortex encodes motion summaries and variability before higher brain regions transform them into category signals. This process, known as ensemble perception, allows the brain to capture the overall structure of a scene at a glance.
Researchers discovered that faster dendrite growth is associated with lower stress levels in a commonly used battery electrolyte material, revealing chemical reactions as a new culprit behind the problem. The study provides guidance for designing stronger electrolytes to make solid-state batteries successful.
Researchers have discovered how the TRPM8 protein changes its shape when exposed to cool temperatures, shedding light on the mechanisms behind cold sensation and pain. The study could lead to new treatments for conditions like cold allodynia and improve our understanding of dynamic proteins.
Research finds that body size and tracheole count can compensate for low atmospheric oxygen levels, challenging the theory of oxygen-constrained insect maximal size. The study suggests alternative explanations for the existence of giant insects during high-oxygen periods.
A team of researchers has discovered that androgens promote the growth of Posterior Fossa Type A (PFA) ependymoma, a lethal pediatric brain tumor. Blocking androgen signaling reduces tumor proliferation, suggesting anti-androgen therapies as a promising treatment option.
Seal whiskers are highly sensitive, but the benefit of active whisking was unclear until new research revealed that it improves sensing. Seals keep their whiskers pulled back and actively move them to detect subtle water vibrations.
Researchers at Cold Spring Harbor Laboratory found that antibodies produced in response to cancer can attack the brain, causing autoimmune diseases like lupus and multiple sclerosis. The study suggests that these antibodies may be harnessed to develop new treatments for triple-negative breast cancer.
Researchers at UC San Francisco have traced the molecular pathway connecting gut immune cells to the brain during a parasitic infection. The study reveals that tuft cells release acetylcholine, which activates vagal nerve fibers carrying signals from the gut to the brain.
A new Stanford University study puts a dollar value on the harm done by carbon dioxide emitted over time, estimating $10 trillion in global economic damages since 1990. The research highlights the critical timing of deploying technologies to remove greenhouse gases from the atmosphere to mitigate damage.
Regulatory B cells produce anti-inflammatory cytokines like IL-10, which dampens inflammatory responses and guides T cells toward regulatory phenotypes. This immune modulation can counteract damaging inflammation and promote neuroprotection.
Researchers found that GH001 significantly improved depression symptoms in patients with treatment-resistant depression, outperforming placebo. The treatment was well-tolerated and suggests a potential novel treatment option.
Researchers found that NUTM1 rearranged leukemia is distinct from other forms, with decreased DNA methylation and increased lifespan of blood cells. Leukemias with BRD9-NUTM1 fusion are extremely sensitive to chemotherapy, leading to improved clinical outcomes.
AI systems demonstrate comparable diagnostic accuracy to dermatologists for melanoma detection, potentially enhancing performance when used as a decision-support tool. However, the risk of bias and limited generalizability of current studies highlight the need for broader validation in unselected patient populations.
Dr. Y. Michael Shim has been named chief of the Division of Pulmonary and Critical Care Medicine, expanding access to comprehensive care for patients with chronic lung conditions. He will lead research and education efforts, including developing innovative imaging technologies to better understand lung disease.
The number of US surgeons sponsored for H-1B visas increased to over 650 in FY2024, with a disproportionate representation in rural and impoverished counties. This trend highlights the need for increased diversity and inclusion in the surgical workforce.
A landmark study published in JAMA Psychiatry suggests that ADHD medication in childhood may reduce the risk of developing serious psychotic disorders later in life. The study found no evidence that treatment with methylphenidate increased the likelihood of psychosis in adulthood.
A recent study found that only a small proportion of elder abuse cases are being officially recorded in hospitals, highlighting a potential reporting gap in Australia's health system. The research analyzed data from nearly one million older Australians and found that physical abuse and neglect were most commonly recorded.
ChatGPT versions showed high rates of inappropriate responses, particularly among economically disadvantaged individuals with psychosis risk. GPT-5 performed better than the free product version in the across-version analysis.
The collaboration aims to assess cross-border climate risk across the minerals-energy-food complex using Jupiter's ClimateScore Global platform. The MEF complex framework examines how climate hazards propagate through supply chains, affecting commodity prices and the pace of the energy transition.
A new study by Finnish researchers found that lower hemoglobin levels within the normal range may be beneficial for glucose metabolism and cardiovascular health. The study, conducted on 64 adults, revealed an association between lower hemoglobin levels and improved physical fitness, heart health, and reduced liver fat.
Scientists have identified a new cell type and discovered that many normal-looking prostate cells harbor cancer-related changes. The study's findings could lead to new risk factors, earlier detection methods, and more targeted therapies for patients at high risk of aggressive disease.
JMIR Publications and the University of Nevada, Las Vegas announce a new Flat-Fee Unlimited Open Access Publishing Agreement. The agreement eliminates financial obstacles for researchers, reducing administrative workload for library staff and ensuring research findings are available via immediate open access in JMIR's high-impact journ...
A new study published in Journal of the American College of Cardiology found that digital CBT significantly reduced cardiac-related anxiety and improved patients' quality of life and physical function after a heart attack. The treatment showed stable benefits up to one year after completion.
Gladstone Institutes has secured over 105,000 square feet of future laboratory space in a newly constructed building, empowering its scientists to create medicines of the future. The new space will be home to approximately 300 scientists across 20 labs, equipped with state-of-the-art equipment and computational abilities.
Researchers at The University of Osaka developed a molecular design strategy to reconcile the trade-off between polymer material's durability and degradability. They created a tough material whose enzymatic degradation can be switched on or off using light, allowing for precise programming of its lifetime.
Researchers successfully captured singlet-fission-amplified excitons with a molybdenum-based emitter, achieving 130% quantum yield and pushing the limits of solar cell efficiency. The team used a metal complex called 'spin-flip' emitter to harvest multiplied energy from singlet fission.
The Lifestyle Medicine Whole Person Health Index (LMWPHI) is a point-of-care assessment tool designed to capture behavior in six pillars of lifestyle medicine, supporting preventive and value-based practice. The LMWPHI is embedded within Epic Foundation systems nationwide, aligning with emerging payment codes and quality priorities.
A landmark study highlights the stability of STEM teacher qualifications and turnover rates in high-need schools, with some improvement in credential alignment. However, gaps in subject-specific qualifications remain, and compensation structures are insufficient to address financial pressures.
The Center for Open Science (COS) has welcomed two new board members, Chris Bourg and Marcus Munafò, to advance the next phase of its work on Lifecycle Open Science. The duo brings expertise in equitable open scholarship, research culture reform, and metascience.