Dr. Childers' research on mucosal immune responses and dental caries vaccine development has contributed to a better understanding of oral health. He currently supervises projects funded by NIDCR, investigating host/parasite relationships in dental caries high-caries-risk populations.
Dr. Sheldon Baumrind is honored for his extensive work in craniofacial biology, including clinical investigation and application of devices and engineering concepts. His research includes articles on randomized clinical trials, radiographic assessment, and orthodontics.
A new study published in PLoS Biology uses magnetoencephalography to record brain activity as humans detect target tones in a complex auditory scene. The researchers find that the awareness of these sounds correlates with activity in high-level auditory regions, not the initial cortical region where sound is processed. This novel study...
Scientists gather to present research on using mechanics to study and explain biology, highlighting the role of faint pushes and pulls in cellular signaling. The symposium aims to develop fundamental math and mechanics to understand biological processes like embryo development and growth.
The UK is launching a Synthetic Biology Initiative with £900,000 funding to establish a world-leading research community. The project aims to bring together biologists, engineers, and computer scientists to tackle future challenges such as sustainable power generation and medical applications.
Three Caltech researchers, David Chan, Michael Elowitz, and Grant Jensen, were selected as new HHMI investigators. They will focus on mitochondrial dynamics, genetic circuits, and biological imaging to advance scientific knowledge dramatically. The selection brings the total number of HHMI investigators at Caltech to 10.
A national survey of teachers found that one in eight high school biology teachers present creationism as a scientifically valid alternative to Darwinian evolution. The majority of teachers spend less than five hours on human evolution, suggesting pressure from the community may influence teaching practices. Raising certification stand...
The University of California, Santa Barbara will receive a $3.2 million grant from the California Institute for Regenerative Medicine to develop a state-of-the-art stem cell research facility. The center aims to foster interdisciplinary research and translation of stem cell-based therapeutics for human diseases.
A new scientific journal uses evolutionary biology to tackle pressing issues such as climate change, food safety, and infectious diseases. The journal features articles that discuss topics ranging from adapting to elevated atmospheric carbon dioxide to predicting the extinction of certain populations due to human-mediated stresses.
Researchers at Brown University found that flies live longer when they don't produce germline stem cells, which create eggs and sperm. This suggests a general principle in biology where reproductive signals directly control lifespan and metabolism in the whole organism.
Cornell researchers have identified 63 proteins in male mosquitoes' seminal fluid that can suppress female appetite for mammalian blood and stimulate egg production. The study's findings could lead to novel strategies to prevent dengue virus spread, a disease affecting 50 million people annually.
Researchers found that rats use exploratory sniffing to discriminate odors quickly, with neural responses confirming minimal processing takes place in the olfactory bulb. The study suggests odorant identity may be encoded by sequence of responses rather than peak activation.
Scott A. Strobel has made seminal contributions to the understanding of RNA structure and function, revealing its catalytic role through various disciplines. He will give the award lecture at the American Society of Biochemistry and Molecular Biology annual meeting.
The genome of Tribolium castaneum, a major agricultural pest, has been fully sequenced. This achievement will enable the development of new methods to protect food plants against beetles. The sequencing also provides valuable insights into the biology of other beetle species.
Researchers have developed new mathematical models to infer ancestral origins from genomic data, significantly improving accuracy. Additionally, a novel technique for mapping disease genes using admixture linkage disequilibrium has been created, offering a powerful approach for identifying genetic determinants of common diseases.
Using a systems biology approach, researchers identified that the master gene controlling the biological clock is sensitive to nutrient status in Arabidopsis. The study provides evidence that plant nutrition affects circadian functions, linking nutrient regulation to biological clock control.
Researchers have found that adult stem cell changes underlie Hutchinson-Gilford Progeria Syndrome (HGPS), a rare genetic disease causing premature aging. The study reveals progerin's effect on adult mesenchymal stem cells, leading to accelerated maturation into bone and loss of fatty tissues.
A new primer on human taste perception and biology has been published, providing a clear overview of recent advances in understanding this primal sense. The study reveals the importance of taste in both positive experiences, such as enjoying food, and critical life-dependent responses, like spitting out toxic substances.
Researchers at University of York characterize mechanism used by bacteria to evade the human immune system, using an 'invisibility cloak' to move about the body without risk of attack. The discovery of a novel enzyme and its role in capturing sialic acid offers hope for developing novel antimicrobials against these bacteria.
A new model system has enabled scientists to conduct powerful genetic studies directly in the parasite Toxoplasma gondii, leading to a better understanding of its biological processes. This discovery could provide valuable leads on how to stop parasite growth and prevent diseases affecting millions of people.
Carlos Castillo Chavez has been honored by the American Association for the Advancement of Science (AAAS) for his efforts to help underrepresented students earn doctoral degrees in the sciences. Through his summer research program, he has mentored numerous Hispanic Americans and Native Americans to graduate programs.
The American Society for Cell Biology (ASCB) is launching a program to support young researcher parents, providing $18,000 'New Scholars' grants to cover childcare expenses during the Annual Meeting. This initiative aims to increase women's participation in science and address family care issues as a barrier to career development.
The iPlant Collaborative, a $50 million NSF grant, unites researchers from various plant biology fields to address 'grand challenge questions' with an all-encompassing computer- and internet-based infrastructure. The initiative also includes outreach materials for students and public education.
Naama Barkai receives the award for her work on chemotaxis, embryonic development, and cellular transcription programmes. Her research has revolutionised the field of systems biology and significantly changed how scientists think about complex biological processes.
A UA-led team has received a $50 million grant to create a global center and computer cyberinfrastructure to address plant biology's grand challenge questions. The project will unite researchers from around the world to advance all fields of plant science.
The Chemical Heritage Foundation will present Leroy Hood with the seventh annual Pittcon Heritage Award for his contributions to instrumental chemistry and genomics. The award recognizes Hood's pioneering work in developing key instruments for modern molecular biology, including the DNA sequencer.
Researchers created a mathematical model of bacterial cell division in Caulobacter crescentus, confirming existing hypotheses and identifying gaps in understanding. The model demonstrates the role of computation in biology and provides a framework for testing predictions and simulating mutant bacteria.
Researchers have designed novel peptide sequences that can detect oxidation and reduction inside cells, providing a new tool for understanding molecular mechanisms underlying complex biomedical problems. The biosensors use Förster resonance energy transfer (FRET) to measure redox potentials and oxidative stress in live cells.
The BBVA Foundation Award for Conservation Biology recognizes Harold Mooney and Peter Raven for their contributions to understanding the evolutionary and co-evolutionary processes that shape plant diversity. Their work has shifted the focus of conservation biology from species-centered approaches to ecosystems and services provided to ...
Researchers have identified a new clock gene, CRY2, that provides insight into the biology of monarch butterfly migration and evolution of circadian clocks. The discovery reveals a dual function of CRY2 as a core clock component and an output molecule linking the clock to the sun compass.
The journal has added several Asian researchers to its Editorial Board, including Professor Huan-Yao Lei as the first Asian Editor. An Asian office will open at NCKU Medical Center in Taiwan, increasing visibility of EBM and SEBM throughout Asia Pacific scientific communities.
A team of biologists has developed a model mapping the control circuit governing a whole free-living organism, allowing for accurate prediction of cell dynamics and adaptation to environmental stresses. The study, based on Halobacterium salinarum, provides insights into how cells make stable decisions in response to their environments.
A new study published in PLOS Biology found that the number of X chromosomes determines the sex of a fruit fly embryo, contradicting previous findings. The researchers discovered that only two X chromosomes can produce a signal to feminize the embryo during a specific stage of development.
Researchers have found a naturally occurring protein called CnAß1 that permanently activates calcineurin, increasing muscle stem cell proliferation and regeneration. This uncouples the protein's activity from injury signals, making it a promising candidate for treating muscle damage and wasting.
Researchers discover that FOXA2 specifies the floor plate and induces dopamine neuron birth, leading to motor deficits and degeneration in mice. This study provides insights into dopamine neuron development and offers potential avenues for treating neurodegenerative diseases like Parkinson's.
A groundbreaking study measures gene activity in malaria parasites in humans for the first time, revealing three distinct biological states and their connection to the body's inflammatory response. These findings may help explain the varying courses of the disease in patients.
The Institute of Genetics and Molecular Medicine (IGMM) brings together researchers in human biology to develop non-toxic cancer treatments that could prevent tumours from spreading. The institute aims to learn lessons from each condition to inform others and develop personalized medical treatment.
The Peking-Yale Joint Center will receive continued and expanded support from Monsanto, enabling graduate student exchanges and plant biology-related programs. The center aims to improve crop production by advancing understanding of plant biology.
Researchers found significant developmental variation in vulva development across nearly 50 species of roundworms. The results show that evolutionary changes are unidirectional and orderly, contradicting the idea of random evolution.
Scientists used a genetic tool to study human embryonic stem cell self-renewal and differentiation. They found that reducing or increasing the expression of oct4 gene induced differentiation, revealing a key difference in early human development regulation compared to mice.
A team of scientists will use a systems biology approach to build a detailed picture of immune system function, focusing on innate and adaptive immunity. The research aims to develop new treatments, diagnostics, and vaccines for infectious diseases.
The University of Leeds is partnering with Dr Tony Marchington's M2 Ventures to offer outsourced research and development in membrane biology to industries. Membrane biology research plays a crucial role in developing pharmaceutical drugs, and the partnership aims to capitalize on this expertise.
Researchers have successfully synthesized a DNA-based memory loop in yeast cells, demonstrating the ability to create a mathematical model that predicts how such a device might work. The memory loop continued throughout many cell divisions, showcasing the potential for biological black boxes with specific functions.
The Biophysical Society has awarded 14 individuals for their exceptional contributions to the field of biophysics. These awards recognize achievements in areas such as lipids and membrane biology, education, single molecule biology, and computational biology.
The team will develop a comprehensive set of hands-on learning activities aligned with the 12 Principles of Plant Biology. The project aims to engage middle school students in plant science education through inquiry-based learning and disseminate the materials to various settings.
Dr. Elliot Meyerowitz has been awarded a grant from the American Society of Plant Biologists (ASPB) Foundation to develop a teacher-training program focused on plant science education public outreach. The program will use plants as model systems to address state biology standards in the Pasadena Unified School District.
Scientists at GIS found that DNA replication efficiency increases later in the S-phase, suggesting a novel approach for studying human biology and stem cell research. The discovery could lead to more efficient analyses and tests related to cellular replication.
Eight scientists and one politician have been recognized by ASBMB for their groundbreaking work, advancing the field of biochemistry and molecular biology. The awards will be presented at Experimental Biology 2008 meeting in San Diego.
New discoveries in ACS Chemical Biology highlight the potential for snail toxins to lead to new drugs, as well as strategies to minimize the side effects of COX inhibitors. The journal also explores how sex hormones activate cell signaling pathways, and helper peptides influence calcium channel opening.
Researchers found that high school math preparation significantly improves college performance in biology, chemistry, and physics. However, no correlation was seen between scientific disciplines, challenging the 'Physics First' movement's arguments.
A Princeton team has created a movie of fruit fly embryo development using physics and molecular biology methods, revealing precise blueprint formation. The researchers found that cells can distinguish between neighboring nuclei based on concentration gradients, a process with sensitivity approaching physical limits.
Recent studies from ACS Chemical Biology reveal new insights into how cells die when chemicals bind to DNA, fast ways to create novel molecules, thyroid hormone regulation, and the regulation of attaching proteins to membranes. The journal provides a platform for exploring cellular function from both chemical and biological perspectives.
Scientists from leading institutions worldwide issue a statement highlighting the critical importance of synthetic biology, citing its potential to solve eco-safe energy issues, outbreaks of malaria, and more. The Ilulissat Statement emphasizes the need for an international effort to advance research while developing protective measures.
The BBVA Foundation is funding 12 research projects in Ecology and Conservation Biology, focusing on climate change's impact on shorebird populations and mercury pollution in biodiversity hotspots. The projects also include studies on noise pollution's effect on tropical birds and the conservation status of the monito del monte marsupial.
A team of researchers discovered a receptor molecule for serotonin plays crucial roles in fear responses to ambiguous stimuli in mice. The hippocampus brain region is involved in processing and assessing value of stimuli, making it easier to interpret situations as threatening.
Researchers have discovered a tool for rapid drug discovery by combining molecular fragments, allowing for more specific targeting of cancer cells. Additionally, two new peptides enable the labeling of proteins, enabling further study and modification.
Researchers have discovered critical regions within prions that determine much of their behavior, providing a new framework for exploring prion biology. These regions, known as recognition elements, can be activated by environmental conditions and amino acid sequence alterations.
Researchers at the University of Illinois have created a new technique to map fruit fly chromosomes, allowing for more accurate study of their structure. This approach uses mechanical devices and computer-based image processing to analyze hundreds of images, providing an impartial estimate of chromosome band locations.
The journal ACS Chemical Biology explores recent discoveries in cellular function, including the inhibition of new blood vessel formation using an antifungal drug. Nanoparticles are also shown to enhance the delivery of short interfering RNAs to cells, potentially aiding clinical applications.
A synthetic drug activates PPAR-d, the master regulator of fat metabolism, making mice resistant to weight gain and increasing their endurance. This breakthrough could lead to a new approach in treating human metabolic syndrome, which includes obesity-related health issues.