American Society for Microbiology honors Jason T. Blackard for his groundbreaking research on HIV and hepatitis C co-infections, including extrahepatic replication of HCV in HIV-infected women.
Dr. Michael Bruce Zwick is honored by the American Society for Microbiology (ASM) for his groundbreaking work in developing an HIV vaccine. He has published numerous papers and received several prestigious awards, including the ICAAC Young Investigator Awards.
Lucas R. Hoffman receives the ICAAC Young Investigator Award from the American Society for Microbiology for his groundbreaking research on biofilm formation and antibiotic interactions. His work has led to significant advancements in the care of patients with cystic fibrosis.
Joanna Kubler-Kielb is honored with the American Society for Microbiology ICAAC Young Investigator Award for her research excellence in microbiology and infectious diseases, including work on anthrax and Lyme disease. Her research has led to significant contributions toward developing new vaccines against these diseases.
Researchers have found that the protective coat of superbug Clostridium difficile can self-assemble into regular shapes, opening up new avenues for fighting hospital superbugs and commercial applications in nanotechnology. This discovery could lead to identifying weaknesses in the coats or discovering new target molecules.
Researchers develop bacteria to deliver anti-cancer treatments by targeting oxygen-starved areas of tumors. The treatment shows effective results in experimental animals, offering a promising alternative to traditional cancer therapies.
Researchers at Tufts University discovered that the CodY protein regulates the genes controlling C. difficile toxin production, which kills human intestinal cells by causing them to burst open. This understanding opens the door for developing a drug that can prevent hospital patients from falling ill.
Scientists developed a microchip that can identify 56 virulence genes in E. coli bacteria and 54 antimicrobial resistance genes in gram-negative bacteria, speeding up diagnosis and treatment of infections. The chip will enable large-scale monitoring of bacterial pathogens and search for important genes in other pathogens.
Researchers have found that bacteria living in red poultry mites could be targeted to prevent Salmonella and other pathogen spread in chickens. The discovery offers a potential new approach to combat the devastating impact of these blood-sucking pests on poultry and human health.
Scientists discover probiotics can reduce Salmonella bacteria in pigs, potentially cutting food poisoning cases. The new technique uses 3D models to test probiotic effects without live animals.
Bacteria and nematode worms work together to kill insects using insecticidal toxins. The toxins, found in Photorhabdus luminescens, are also found in human pathogens Yersinia pestis and Yersinia pseudotuberculosis.
Researchers at Nottingham University have identified antibodies that can prevent infection with various strains of Hepatitis C virus in laboratory models. This breakthrough could lead to the development of a vaccine, which would significantly improve healthcare benefits for those suffering from hepatitis.
Scientists have discovered thousands of new compounds in marine sponges, which are made by the bacteria living inside them. However, growing these bacteria in the laboratory is difficult due to the unique environment inside the sponge.
Low-salt foods are as safe as high-salt ones in terms of bacterial spoilage, according to a study. The researchers found that different strains of bacteria showed no significant difference in growth rates regardless of the salt concentration tested.
Hepatitis E virus has been detected in European pigs and pork products, posing a risk to human health. The disease is often fatal for pregnant women and can be transmitted through direct contact with animals or contaminated food.
A new risk assessment tool has been developed to help reduce the transfer of disease-causing bacteria from farmed environments to watercourses. The expert-weighted risk tool identifies fields and farmyards with the greatest likelihood of contaminating waterways, allowing farmers and landowners to prioritize clean-up efforts.
A 2-year survey in Ireland aims to determine how the bacteria enters the food chain. Scientists analyzed 1,800 pig tissue samples and found non-disease causing Yersinia enterocolitica in 12 samples and disease-causing genes in 15 samples.
A team of scientists has found a reliable and cost-effective method to extend the shelf life of cooked ham to 39 days by using a protective culture of Lactobacillus sakei. The treatment resulted in a more acceptably taste, texture, and overall quality compared to conventionally preserved ham.
Scientists discover new viruses that target specific types of bacteria, offering an alternative to conventional antibiotic therapy. The approach has potential to combat antibiotic resistance and superbug infections such as MRSA.
Year-round consumption of fresh leafy greens like lettuce poses challenges due to increased risk of E. coli contamination from field sources. New methods, including harvesting mowers and triple washing, are being used to address this issue.
A team of researchers at the University of Illinois found that tetracycline resistance genes migrate from hog waste lagoons into groundwater wells, often diluting or amplifying these genes. The study, published in Applied and Environmental Microbiology, tracks the passage of these genes across species and environments.
The American Society for Microbiology's MicrobeWorld Radio podcast and Small Things Considered blog have received a Communication Gold Circle Award for their innovative communication campaigns. The award recognizes the programs' ability to increase public understanding of microbiology and scientific careers.
Research by UCF Professor Keith Ireton and colleagues reveals Listeria protein InlB induces internalization of human receptor Met, implicated in some cancers. Understanding this mechanism may lead to drug development targeting Met-related cancers.
The American Society for Microbiology (ASM) received three honors at the 2007 Hermes Creative Awards, including a Platinum Award for its MicrobeWorld Radio audio and video podcasts. Its blog, Small Things Considered, won a Gold Award, while its website earned an Honorable Mention.
Oxygen restriction increases Listeria's infective potential by allowing it to smooth its path through the gut and liver, increasing the risk of infection.
Researchers found that C. difficile expresses its pathogenicity during periods of nutrient deprivation, potentially leading to a new treatment approach. A five-gene region, known as the tcd locus, plays a crucial role in toxin production and cell membrane disruption.
Research suggests that food can be an important avenue for antibiotic-resistant bacterial evolution and dissemination through horizontal gene transfer with commensal bacteria. Many food samples tested contained antibiotic-resistance gene-carrying bacteria, highlighting the prevalence of these microbes in the retail food supply.
Researchers have identified a bacterium that repels a deadly fungus causing worldwide amphibian deaths and extinctions. The discovery could lead to procedures for 'vaccinating' endangered populations.
Rising global temperatures are expected to alter infectious disease patterns, with increased transmission of diseases like malaria and influenza. Climate change is also linked to water-borne diseases, as extreme weather events strain aging infrastructure.
Researchers at Albert Einstein College of Medicine found fungi can harness ionizing radiation to produce food and spur growth, recalculating Earth's energy balance. This discovery could provide a sustainable food source for long-duration space missions or planetary colonization.
High-salt diets may increase the risk of severe gastric disease by inducing gene activity in H. pylori, making it more virulent. The study found that bacterial cells exposed to high salt concentrations exhibited morphological changes and increased transcription of virulence genes.
Researchers found hundreds of new species of bacteria that can break down petroleum products, including those surviving without water or oxygen. The bacteria have potential applications for cleaning oil spills, medical treatments, alternative energy, and industrial uses.
Researchers have discovered a weakness in the armour that protects B. cenocepacia from antibiotics, identifying a key sugar required for its protection. This finding may lead to novel molecules to disrupt its synthesis and develop new treatments.
Researchers at Ohio State University discovered that bacteria can turn genes on or off to control their infectiousness. The proteins NusG and RfaH play a crucial role in this process, with NusG regulating nearly all gene expression in bacteria and RfaH controlling specific sequences of the genome during transcription.
The 2007 Amgen Biochemical Engineering Award was awarded to Professor George Georgiou for his groundbreaking contributions to protein engineering, protein-based therapeutics, and fundamental understanding of protein biogenesis. He has also made significant discoveries in RNA degradation, oxidative protein folding, and protein secretion.
The LA Times reporters were recognized for their outstanding journalistic achievement in raising public awareness about human-caused ocean microbiological changes. Their 5-part series, Altered Oceans, explained how overfishing and waste dumping are creating a biological imbalance in the world's oceans.
A new study has developed an antimicrobial approach using gallium to defeat drug-resistant bacteria. The researchers interfered with a key bacterial nutrient, killing microbes in laboratory experiments and eliminating life-threatening infections in mice.
A new type of protein discovered by Queen's University researchers may be useful in developing treatments for antibiotic-resistant bacteria. The protein, called YihE or RdoA, has been shown to be a potentially good target in a wide range of bacteria that cause infectious diseases.
The team of scientists deciphered the genome of Trichomonas vaginalis, a single-celled parasite causing trichomoniasis, which affects an estimated 170 million people annually. The large genome contains nearly 26,000 confirmed genes, providing new insights into pathogenesis and potential therapeutic targets.
A study by Cornell and US Military Academy researchers found that waste and drinking water treatments, including UV radiation and bacterial digesters, can eliminate avian flu viruses. H5N2, a low-pathogenic virus similar to deadly H5N1, was inactivated at levels within industry standards.
Researchers propose that microorganisms can thrive in the Deep Biosphere due to natural radioactivity, offering an alternative energy source. This process, radiolysis, creates hydrogen and oxygen, providing sufficient energy for life forms to survive without surface processes.
An international team of researchers has identified genes in Ustilago maydis that help the fungus live at its host plant's expense without killing it. The findings could lead to new ways to combat this fungus, which affects maize and other crops worldwide.
Researchers at Albert Einstein College of Medicine successfully targeted and destroyed HIV-infected cells in mice using radioimmunotherapy. The treatment aims to eliminate the virus-infected cells that make infections chronic, potentially leading to a cure for HIV-infected patients.
A study published in Nature found that the reconstructed 1918 influenza virus induces a potent immune system response in mice, yet fails to prevent severe lung disease and death. Researchers hope to understand the trajectory of this infection and develop targeted therapies for other viral infections.
Researchers found that B cells expressing a special protein called DC-SIGN are necessary for HIV to infect T cells. Activating DC-SIGN on B cells allows HIV to invade T cells, highlighting a new target for future studies and drug development.
Researchers at Albert Einstein College of Medicine have developed a novel technique to insert genes into the P. falciparum genome, providing valuable information about its virulence and resistance to antimalarial drugs. This breakthrough should significantly speed up research efforts to bring malaria under control.
Researchers at the University of Montreal have identified defective immune cells as a primary cause of fungal infections, such as candidiasis, in HIV patients. This discovery could lead to more effective treatments for these debilitating conditions.
The overuse of antibiotics in fish farming can lead to increased bacterial resistance and disease risk. Consuming contaminated fish products can transfer these resistant bacteria to humans, posing a significant health threat.
Scientists have discovered a link between bacterial growth fueled by algae and the death of corals. The study shows that bacteria suffocate corals by cutting off oxygen supply, leading to a positive feedback loop that accelerates reef decline. Human activities such as overfishing, pollution, and climate change exacerbate this process.
Researchers have gained insights into the genetic mechanisms of Proteus mirabilis, a bacterium causing kidney stones and complicated urinary tract infections. The complete genome sequence, including 3,693 genes and 4.063 megabases of DNA, will help scientists identify potential targets for new vaccines.
The DOE JGI has completed its 100th microbial genome sequencing, marking a significant achievement in the field of microbiology. This milestone allows researchers to explore and expand their understanding of microorganisms' metabolic profiles and environmental implications.
A team of Rutgers University researchers has made a breakthrough in finding a microbial approach to clean up MTBE contaminated groundwater. By employing carbon isotope fractionation, the team can identify the key bacteria capable of breaking down MTBE and potentially speed up the process.
A recent study published in Environmental Microbiology found that snakes become infected with Salmonella through exposure to contaminated environments, not just by eating contaminated food. The knowledge gained from this study can help prevent reptile-associated infections and inform safe handling practices for snakes and other pets.
Researchers at the University of Illinois have discovered a protein, MC160, that inhibits inflammatory responses by degrading a subunit of the immune system's IKK complex. This finding offers hope for treating conditions such as rheumatoid arthritis and Crohn's disease.
Researchers at Thomas Jefferson University have identified a molecular mechanism involved in making the rabies virus pathogenic and lethal. They have developed a very safe vaccine for the immunization of wildlife, showing efficacy in raccoon, skunk, and mongoose species, offering new hope for prevention of deadly disease.
Researchers found that a specific gene, SPRN6, is switched on in mosquitoes infected with the malaria parasite, allowing them to defend against it. By knocking out this gene, they observed increased parasite development in some mosquito species and delayed parasite lysis in others.
Scientists at Vanderbilt University Medical Center discovered compounds secreted by frog skin can selectively kill HIV without harming T cells. The findings hold promise for developing new treatments and vaccines against the virus.
Researchers discovered a unique partnership between Osedax worms and their symbiotic bacteria, allowing them to turn over large amounts of organic carbon at an accelerated rate. This process can potentially aid understanding of adaptation between animals and microbes.
New research reveals that rifamycin antibiotics work by removing a crucial magnesium ion from bacterial RNA polymerase, rendering the bacteria non-functional. The study's findings may lead to improved versions of these antibiotics to combat existing resistant strains.
Researchers at the University of Pennsylvania School of Medicine have found that inhibitors of cellular enzyme cathepsin L prevent the SARS virus from entering target cells. This breakthrough discovery could lead to the development of new therapeutics against the SARS virus.