A population-based study found that nearly half of men with low-risk prostate cancer transitioned from active surveillance to definitive treatment within five years after diagnosis. The study, published in The Journal of Urology, analyzed data from 8,541 men and identified factors associated with the likelihood of transition, including...
A study highlights the need for better diagnostic tools, alternative treatments, and prevention strategies for women with recurrent UTIs. Women report feeling frustrated with their doctors' overuse of antibiotics and lack of education on preventing UTIs.
The American Board of Urology has outlined processes to promote diversity, equity, and inclusion in its leadership structures. The report highlights the need for continuous efforts to improve representation, particularly in terms of gender and racial/ethnic diversity.
New research suggests that closely monitoring low-risk prostate cancer can be as effective as active treatment in reducing mortality rates and preserving sexual function. This approach allows men to live with the disease for ten years or more without treatment, while still being unlikely to die from it.
A phase 3 trial found that Lu-PSMA-617 significantly improved survival and progression-free survival of patients with metastatic castration-resistant prostate cancer. The treatment delivered beta radiation directly to tumour cells, keeping them alive for longer than standard care.
A new study found that obese patients with advanced prostate cancer survive longer than their overweight and normal-weight counterparts. Obesity was associated with a 10% higher survival rate over 36 months. The 'obesity paradox' suggests that high body mass index may be protective in certain cases.
A new study found that using an existing immunotherapy drug for late-stage kidney cancer at an earlier stage can reduce the risk of cancer returning by a third. The KEYNOTE study involved over 1000 patients and showed similar side effects to other cancer treatments.
A new study found that a stunning virtual reality setting can reduce pain caused by uncomfortable medical procedures, such as cystoscopies. The research used VR headsets to present patients with a calming Icelandic landscape, resulting in lower pain scores and reduced anxiety.
A new study suggests that magnetic resonance imaging (MRI)-based screening can reduce unnecessary biopsies and detect clinically significant tumours while halving overdiagnoses. The results come from a randomized study conducted at Karolinska Institutet in Sweden.
A new study found that supplementing testosterone significantly reduces heart attacks and strokes in men with unnaturally low hormone levels. The 10-year study involved over 800 men from Germany and Qatar, showing a 25% reduction in risk for those under 55 and a 15% reduction for those over 60.
A pilot study found that patients with high cotinine levels were four times more likely to have their cancer return. The researchers aim to develop a simple urine test for cotinine to reduce invasive investigations for bladder cancer patients.
Research reveals that women with urinary incontinence are more likely to experience depression, lower self-worth, and poorer mental health outcomes. The study emphasizes the importance of discussing mental health with patients undergoing treatment.
Research shows that men with symptomatic Covid-19 and low testosterone are more likely to become severely ill and die. The lower the testosterone levels, the higher the likelihood of severe illness and death, according to a study presented at the European Association of Urology congress.
Researchers developed a novel treatment using stereotactic ablative radiation (SABR) to deliver high doses of radiation to tumor vein extensions. The approach has shown promise in reducing metastases and improving patient outcomes.
Researchers found that urine protein biomarkers IL-1α, IL-1ra, and IL-8 can distinguish bladder cancer from controls with high accuracy. These markers also show promise in discriminating between different stages of the disease.
A study found patient satisfaction scores differed significantly among patients with different types of insurance coverage, with Medicare scoring the highest and Medicaid the lowest. The researchers call for further studies to explore the underlying reasons for this payor-specific bias.
A new AI-based scoring model for testis images has been developed to assess patients with severe male infertility, simplifying the diagnosis process. The model achieved high accuracy in classifying histological images of the testis, with an average precision of 82.6% and recall of 60.96%, without requiring programming expertise.
A new study found a 36% decrease in prostate cancer diagnoses in Sweden during the first pandemic wave, with most pronounced declines among men aged 75 and over. The number of patients receiving curative treatment remained unaffected, suggesting that healthcare prioritized cancer care during the pandemic.
Dr. Lindsay Hampson, a UCSF researcher, has received the AGS' Jeffrey H. Silverstein Memorial Award for her work on improving patient-centered decision-making for older adults with urologic conditions. Her study found that multimorbidity, frailty, and mortality risk are common among older men with stress urinary incontinence.
Researchers at Einstein College of Medicine developed a topical drug that regenerates and restores function of erectile nerves damaged by radical prostatectomy. The siRNA gel enhanced nerve regeneration and restored nerve function in rat models, restoring erectile function.
A Korean research team has developed an innovative treatment method for vesico-vaginal fistulas using a mussel adhesive protein-based bioadhesive. The new method shows promise in sealing fistulas quickly and effectively, with improved outcomes compared to conventional suture methods.
A urine test has been found to be extremely accurate at detecting aggressive prostate cancer with few false negatives. The test avoids unnecessary biopsies for patients with slow-growing or no cancer, reducing costs and invasive procedures.
A study by researchers at UCLA Jonsson Comprehensive Cancer Center found that MRI frequently underestimates the size of prostate tumors, which can lead to undertreatment. The accuracy of treatment depends on precise measurements of both tumor size and PI-RADS score.
A phase 3 clinical trial found that ipilimumab improved progression-free survival by two to three times in patients with metastasized, castration-resistant prostate cancer. The treatment also showed overall survival benefits compared to the placebo arm.
A European survey found that a majority of men and women aged 20-70 do not know what erectile dysfunction (ED) is, with one in four having never heard of ED treatments. The study emphasizes the need for open communication about ED to break the taboo and improve treatment outcomes.
Smokers have worse chemotherapy response and higher mortality rates from bladder cancer, with a higher risk of cancer recurrence. Former smokers also fare poorly in these categories.
During the pandemic, an online urology lecture series has provided invaluable training opportunities for resident physicians, with thousands of views and overwhelmingly positive reviews. The multi-institutional collaboration, Urology COViD, has been a smashing success, offering a sense of community connectedness during social isolation.
A new study suggests that focal high-intensity focused ultrasound (HIFU) ablation is an effective alternative to surgery or radiation for treating prostate cancer. The procedure carries a low risk of complication and helps preserve quality of life, with no significant decrease in sexual function or urinary incontinence.
A global methodology has been developed to help decide when to treat prostate cancer, providing a single standard for estimating tumour aggressiveness. The GAP3 consortium's analysis of 14,380 patients reveals that certain factors can predict cancer development, enabling more informed treatment decisions.
Researchers found that men are now more likely to visit clinics for Peyronie's disease and low sexual desire, while erectile dysfunction cases have declined. The study suggests a growing awareness of these conditions, possibly driven by increased openness and access to treatments.
A major study conducted by patients themselves reports significant numbers struggling with continence and sexual problems after prostate cancer treatment. The Europa Uomo Patient Reported Outcomes Study found that any treatment apart from active surveillance negatively affects quality of life.
A study found that women taking MHT have a greater variety of beneficial bacteria in their urine, potentially creating conditions that discourage urinary infections. The study also showed that women with recurrent UTIs have fewer types of bacteria in their urine.
Researchers found the AZIN1 gene associated with metastatic prostate cancer, with reduced expression leading to fewer metastases. Further investigation is needed to confirm findings in all prostate cancers.
A new toolkit has been developed to help medical organizations rapidly adopt telemedicine as an alternative option. The guide uses a common electronic medical record system and widely available video portals to overcome social distancing edicts, allowing for successful adoption in three days.
Researchers found six substances with a strong link to bladder cancer in the urine of e-cigarette users, including carcinogens from combustion products and other tobacco products. The study's findings suggest that vaping may expose users to carcinogens similar to those found in cigarette smoke.
A new clinical trial led by Keck Medicine of USC is investigating the effectiveness of Transcutaneous Electrical Spinal Cord Neuromodulation (TESCoN) in treating overactive bladder due to neurological conditions. The trial aims to improve patients' sense of well-being by enhancing bladder control and reducing symptoms.
Researchers at MDC have found a weakness in the most common form of kidney cancer by identifying stem cells that depend on two critical biochemical signals. Blocking these signals hinders tumor growth in several laboratory models, suggesting a promising new approach to treating human patients.
A new study published in The Journal of Urology found that most patients who underwent prostate cancer surgery experienced low levels of decision regret. Patients who played a more active role in treatment decision-making were less likely to experience regret about their choices, regardless of whether they opted for robot-assisted or o...
A new study published in The Journal of Urology found that a low-fat diet may be associated with lower testosterone levels in men. The study analyzed data from over 3,100 men and found that those on a low-fat diet had lower serum testosterone levels compared to those on an unrestricted diet.
A recent UCSF study reveals a significant spike in e-scooter-related injuries and hospital admissions, mainly among young adults. The number of scooter-related injuries increased by 222 percent between 2014 and 2018, with nearly 40,000 injuries reported.
A study from UT Southwestern Medical Center found that individualized physical therapy can effectively reduce urinary incontinence and pain in men after prostate surgery. The approach focuses on relaxing tight pelvic muscles rather than strengthening weak ones, leading to improved outcomes for 87% of patients.
A new study published in BJU International found that short-term exercise can reduce the adverse effects of hormone therapy on cardiovascular fitness and fatigue. Patients who underwent supervised aerobic and resistance training experienced improved cardiopulmonary fitness, reduced fatigue, and enhanced quality of life.
The Milton and Carroll Petrie Department of Urology at Mount Sinai has received a $1 million grant from The Arthur M. Blank Family Foundation to fund the Prostate Cancer Program. The program aims to advance immunotherapy and personalized genomic vaccine trials aimed at treating prostate cancer.
A study has identified a novel biomarker, KLK4-KLKP1 fusion gene, detectable in urine samples of patients with prostate cancer. This non-invasive method may replace traditional PSA tests, reducing unnecessary biopsies and improving diagnosis accuracy.
Scientists at Stanford University School of Medicine have discovered a molecular pattern that flags prostate enlargement and identified two genes likely playing a role in its development. The researchers found that only certain cell types multiply, leading to a fundamental shift in the type of cells making up the prostate.
A new urology care model developed by Flinders University focuses on supporting bladder cancer patients' partners and family, addressing their daily impacts and needs. Health professionals can capitalize on this by providing clear information, counseling, and support to manage the shock, fear, and treatment of bladder cancer.
A specialized pain management program for robotic urologic surgery patients resulted in a significant reduction in opioid prescriptions. The study found that just 8% of patients were prescribed opioids after discharge, with those who received them going home with fewer pills than usual.
Researchers found widespread inconsistencies in antibody use, causing unreliable results and wasting $2 billion per year. They call for industry-wide standards to validate antibodies, especially in human tissue research.
A new study published in the Journal of Urology found that transperineal prostate biopsies (TPBx) under local anesthetic are the safest method for testing and diagnosing prostate cancer, with fewer complications and improved patient tolerability.
A computational tool assigns a bladder cancer subtype to an individual patient using genomic data, enabling personalized treatment selection. The study found that patients with the aggressive 'neuronal' subtype responded well to atezolizumab treatment, achieving high survival probabilities.
Men undergoing hormonal treatment after prostate removal are 80% more likely to suffer from depression, according to a study presented at the European Association of Urology congress. The treatment is given to control tumor growth, but it may also affect men's well-being.
A new study reveals that patients with prostate, bladder, or kidney cancers who have had psychiatric care prior to treatment are at a greater risk of dying. The research also found an increased suicide risk among these patients, even after adjusting for previous mental health treatment.
Scientists have identified two coffee compounds, kahweol acetate and cafestol, which inhibit the growth of prostate cancer cells in cell culture and animal models. The study's findings suggest that these compounds may be used to treat drug-resistant prostate cancer, with further investigation needed.
Researchers have discovered that sperm DNA taken directly from the testicles of infertile men is as good as that of ejaculated sperm from fertile men, potentially opening a new way for treatment. This finding may explain a major cause of male infertility and could lead to improved fertility outcomes.
Researchers have found that testosterone replacement therapy reduces prostate cancer recurrence in low-risk patients by nearly three-fold over three years. This study challenges the long-held notion that testosterone promotes prostate cancer and suggests a potential new treatment approach for these patients.
Researchers found that night shift workers reported a higher rate of overactive bladder and poorer quality of life compared to day shift workers. The study highlights the importance of addressing increased urinary frequency in nightshift workers, particularly those under 50 years old.
Researchers found that men with high neuroticism are more likely to experience adverse events after prostate cancer surgery, such as erectile dysfunction and incontinence. The study suggests that personality tests may be a valuable tool for identifying at-risk patients and improving care.
Research links early menopause to increased bladder cancer risk, particularly in smokers. The study found that women who went into menopause before the age of 45 were 45% more likely to develop bladder cancer than those who had later menopause.
The Polsky Urologic Cancer Institute will provide personalized, integrated, and innovative care to individuals with urologic cancers through a disease-centric program of research, education, and discovery. The institute aims to transform how urologic cancers are treated in Chicago and worldwide.
Case Western Reserve University researcher Sanjay Gupta has been awarded nearly $1 million to investigate drug resistance mechanisms in prostate cancer. He will test two promising medications, simvastatin and metformin, to overcome drug resistance and halt metastasis.