A study published in the Journal of Urology found that up to 30% of men on active surveillance for low-risk prostate cancer may have metastases. Risk factors include Gleason score 7 and presence of Gleason pattern 4 on diagnostic biopsy.
A new thematic issue of The Open Urology & Nephrology Journal reports on the association between hyperuricemia and kidney disease. Chronic inflammation is a common link between the two conditions, with research exploring its role in uric acid excretion and progression of renal disease.
A new study found that active surveillance for low-risk prostate cancer significantly improves urinary function, reduces incontinence, and enhances sexual satisfaction. Men on active surveillance reported a similar quality of life to those without cancer, highlighting its potential as an alternative to curative treatment.
Researchers have identified new prostate cancer markers in urine that show high specificity and sensitivity. A combination of these biomarkers could lead to a more accurate and reliable test for early diagnosis.
A new survey found significant country-to-country differences in kidney transplant donation rates, varying by up to 35 donors per million population. The variation is attributed to different legal and social standards across Europe, with some countries having more generous organ donation schemes than others.
Men with fertility problems are at higher risk of metabolic diseases such as osteoporosis and diabetes. Researchers found that one-third of infertile men under 50 have biochemical signs of low sex hormone levels, which can lead to fractures and increased glucose levels.
A new study suggests that poor sleep, like sleep apnea, can promote cancer development by stimulating the formation of blood vessels in tumors. Researchers found that intermittent hypoxia, a common consequence of sleep apnea, increases vascular progenitor cells and endothelial cells within tumors.
Researchers at UT Southwestern Medical Center found that light reflectance spectroscopy can differentiate between malignant and benign prostate tissue with 85% accuracy. This technology aims to improve surgical decision-making and reduce the amount of healthy tissue removed during prostate cancer surgery.
A meta-analysis published in European Urology found that vaginal delivery increases the risk of stress urinary incontinence by almost twice, with an absolute risk increase of 8%, compared to caesarean section. The effect is more pronounced in younger women and decreases over time.
A consensus meeting of experts has established a framework for classifying bladder cancers based on genetic mutations. This development aims to improve patient outcomes by stratifying patients according to their tumor characteristics and response to therapy.
The American College of Physicians (ACP) offers guidance on evaluating blood in the urine, emphasizing the importance of referring patients with gross hematuria and confirming heme-positive results. For adults with microscopically confirmed hematuria, urology referral for cystoscopy and imaging is recommended.
The American College of Physicians issues guidelines for evaluating blood in the urine as a sign of cancer. Doctors should confirm heme-positive results with microscopic urinalysis before initiating further evaluation in asymptomatic adults. Urology referral is recommended for cystoscopy and imaging in adults with microscopically confi...
A recent study published in The Journal of Urology found that reduced prostate needle biopsies are associated with a higher risk of being diagnosed with high-risk disease. This could lead to delayed diagnosis and potentially avoidable cancer deaths. The study's findings highlight the need for balanced screening approaches and more effe...
A new study published in The Journal of Urology finds that female urologists earn approximately $76,000 less than men annually, despite a significant increase in women entering the field. Despite income disparities, female urologists report high levels of job satisfaction.
A new study found that African American men with low-grade prostate cancer produce less PSA and have significantly lower PSA density than Caucasian men. This could lead to inaccurate surveillance criteria and affect treatment decisions for African American patients.
A study published in The Journal of Urology found that patients with low mental health self-assessments before radical cystectomy had higher rates of high-grade complications, highlighting the importance of preoperative assessment.
PSA testing has declined dramatically in middle-aged men after a 2012 recommendation against routine screening, according to a new study. The biggest declines were seen in men ages 50-54 and 60-64 years old.
Five researchers have been awarded Ferring Innovation Grants to support groundbreaking research in Reproductive Health, Gastroenterology, and Urology. The winners are working on innovative projects including immunomodulation of RELMβ for IBD and targeting Cripto in castration-resistant prostate cancer.
The new guidelines promise to improve the detection of life-threatening tumors and reduce unnecessary biopsies, with the potential to save lives. The standards for acquiring and reporting MRI scans will be widely adopted, making it easier for doctors to identify significant cancers.
A recent study by UC San Francisco found that bicycle accidents among riders older than 45 have increased significantly, resulting in more hospitalizations. The study showed a 66% increase in hospital admissions to older riders and an 81% rise in injuries occurring to riders above age 45.
Surgeons report positive outcomes in robotic IVC thrombectomy for renal cancer patients with Level III thrombus. Eight out of nine patients show no evidence of disease after follow-up, with significant advancements in operating room times and blood loss.
Researchers found that men with low-risk prostate cancer are increasingly opting for active surveillance, while those with higher-risk tumors are receiving more aggressive treatments. This shift aims to reduce overtreatment and improve outcomes for patients.
A new study published in the Journal of the American College of Surgeons found that the 2011 duty hour reform did not decrease serious postoperative complications in surgical patients. The researchers evaluated outcomes in five surgical specialties, including neurosurgery, obstetrics/gynecology, and vascular surgery, and found no signi...
Implementing video-based decision aids in urology led to fewer elective surgeries for benign prostatic hyperplasia and localized prostate cancer. Rates of surgical intervention declined by 32% for treated BPH patients and 27% for localized prostate cancer patients.
A new study identified older white males with advanced bladder cancer as a high-risk group for suicide. Researchers found that these patients have a higher suicide risk compared to those with other genitourinary cancers.
A new, shortened test to assess frailty can accurately determine which surgical patients are most at risk for complications. The test, taking less than a minute, assesses grip strength and weight loss, providing critical information for patient planning and setting expectations.
A comprehensive, population-based regional health care management program for men with prostate cancer has led to improved outcomes. The program includes safety-net screening programs, improved surgical procedures, and enhanced drug management, resulting in lower rates of blood loss and osteoporosis-related complications.
Close monitoring of small renal tumors can be an alternative to surgery, with low rates of tumor growth or death observed. The study's findings suggest that actively monitoring these tumors in high-risk patients may prove safer than immediate surgery.
Researchers found that higher-earning clinicians earn more by providing more services per patient, rather than seeing more patients. This challenges the current fee-for-service payment model, which may not incentivize clinicians to prioritize quality of care.
Researchers found that cancer stem cells regrow and respond to chemotherapy-induced damage by releasing prostaglandin E2, leading to therapy resistance. Blocking PGE2 could potentially enhance therapeutic response, offering a promising new treatment for bladder cancer.
A new study published in European Urology has found that androgen deprivation therapy (ADT) is associated with decreased survival in men with localized prostate cancer, particularly those with longer life expectancies. The research highlights the need to reconsider the use of ADT as a primary treatment for low-risk or localized cancers.
A new study published in The Journal of Urology analyzed data from three independent registries and found no increase in prostate cancer incidence among men treated with long-term testosterone therapy. The study followed over 1,000 men for up to 17 years, with a median follow-up of approximately 5 years.
Researchers found that higher volume hospital and surgeon volume are associated with fewer post-operative complications and improved overall survival for bladder cancer patients. The study aims to identify processes and interactions leading to better outcomes, which could inform improvements in care at lower volume hospitals.
A new study found that two-thirds of health websites recommending prostate cancer screening aligns with medical organizations' stance. Many online resources advocate for patient-individualized approaches, while some sites advise against screening due to potential risks.
A study evaluated the rate of physician adherence to American Urological Association's BPH/LUTS guidelines over a five-year period. Provider adherence rates varied from 53% to 92.8%, with low rates for challenging measures like subjective symptom description and physical examination.
A joint FDA advisory panel recommended changes to testosterone product labels and required drug makers to conduct tests on cardiovascular risk related to testosterone therapy. The panel's focus was on male age-related hypogonadism, which affects approximately 20-30% of men ages 40-79 years old.
Children who start toilet training before age 2 have a three times higher risk of developing daytime wetting problems later, according to new research. Early trainers are more prone to subsequent voiding dysfunction due to holding stool or urine, reducing bladder capacity and causing nerve damage.
Researchers at USC Keck Medicine have discovered a dual purpose of the cancer drug decitabine in regulating gene expression. The study found that the drug not only reactivated tumor suppressor genes but also down-regulated overexpressed oncogenes, which are responsible for cancer progression. This new mechanism may provide additional t...
Researchers found that girls with vulvitis were eight times more likely to have a lab-diagnosed UTI than those without vulvitis. Vulvitis may cause UTIs by altering the type of bacteria normally found in the area between the vagina and anus.
A nationwide population-based study in Sweden found that six percent of men filled a prescription for antibiotics within 30 days after having a prostate biopsy, with a twofold increase in hospital admissions over five years. Men with prior infections or significant comorbidities were at highest risk.
A study published by Henry Ford Hospital researchers found that deaths from complications following urologic surgeries increased as procedures shifted from inpatient to outpatient settings. High-risk patients, including older and sicker individuals with public insurance, were more likely to die after potentially preventable complications.
A recent study published in BJU International found a significant increase in preventable deaths following common urologic procedures in the US. The study analyzed discharge records of patients undergoing urologic surgery between 1998 and 2010, revealing that mortality rates remained stable while failure to rescue rates increased.
A large study published in European Urology has found that needle-guided tumor destruction procedures, such as partial nephrectomy and radiofrequency ablation, offer near equivalent lengths of local cancer control compared to surgery for patients with small kidney cancer tumors.
Researchers analyzed bladder biopsies from patients with suspected interstitial cystitis and those without the disease. The study found a significant difference in gene expression between low capacity patients and both normal capacity and control patients, suggesting a potential sub-type of IC.
Researchers have developed a first-of-its-kind molecular test kit that can predict treatment and survival outcomes in kidney cancer patients based on their tumor profile. The assay was able to distinguish patients into groups with different survival and treatment outcomes, allowing for more educated choices in treatment options.
A study published in Journal of Pediatric Urology found that for most children with antenatal hydronephrosis, continuous antibiotics are not needed. The research suggests that prophylactic antibiotics are only necessary for those with severe conditions, reducing the risk of urinary tract infections.
A new study by Henry Ford Health found that robot-assisted surgery can control prostate cancer for up to 10 years. The research followed 483 men who had not spread cancer beyond the prostate and received robot-assisted radical prostatectomy (RARP) as their first treatment, with 98.8% surviving the disease for 10 years.
Surgical residents who received anonymous peer feedback through a social networking site improved their robotic surgery skills more than those without feedback. The study found that residents in the intervention arm completed procedures faster and earned better scores.
A US study found that prostate cancer surgery costs varied greatly among hospitals, with a 13-fold price difference. The study also highlighted the lack of transparency in hospital pricing, making it difficult for consumers to compare costs.
A commercial epigenetic diagnostic test has been found to be accurate enough to exclude the need for repeat prostate biopsies in many men. The test analyzes DNA hypermethylation levels in specific genes and shows an 88% likelihood of no cancer when all three biomarkers are absent.
A recent study by Northwell Health demonstrates that magnetic resonance imaging (MRI) guided biopsies can detect prostate cancer more accurately, with a detection rate twice as high as previous data. The new targeted approach uses MRI and transrectal ultrasound fusion to identify clinically significant prostate cancer.
Richard Sylvester, a renowned expert in non-muscle invasive bladder cancer (NMIBC), received the 2014 Platinum Award from European Urology for his excellence in bladder cancer research. He continues to work on prognostic factors and predictive effects of age on NMIBC outcomes.
A new UCLA study reveals that conventional biopsies may fail to detect aggressive cancers in men with low-risk prostate cancer, highlighting the need for a targeted biopsy approach. The findings suggest that the criteria for active surveillance should be re-evaluated to account for the risk inflation seen with targeted prostate biopsy.
Researchers at Mount Sinai present landmark studies on an immune response in prostate cancer tumors, effects of paternal age on live birth rates and treatment modalities for benign prostatic hyperplasia. The studies demonstrate complexities of immunotherapy and its impact on survival rates and fertility outcomes.
The new journal Urology Practice will focus on clinical trends, challenges and practice applications in the four areas of Business, Health Policy, Specialty and Patient Care. It aims to provide information that can be used in everyday practice through peer-reviewed articles and other content.
A new method using existing ultrasound scanners allows doctors to accurately detect prostate cancer with much greater precision, reducing the need for painful biopsies. The technique saves money by eliminating costly biopsy analysis and can potentially eliminate biopsies altogether.
Henry Ford Hospital has implemented a kidney transplant technique using new patient safety standards coordinated by the University of Oxford. The IDEAL framework was used to develop and test the minimally-invasive procedure, which successfully transplanted kidneys in 50 recipients.
The number of PSA screenings performed by doctors declined significantly after the 2012 USPSTF recommendations, with a greater impact seen among urologists.
Patient satisfaction with treatment is greater when outcome information is specific to their treating physician, according to a study. This type of information helps patients set realistic expectations and make informed decisions about therapy selection.
A UCLA study published in European Urology found that robotic-assisted prostate surgery resulted in 5% fewer positive margins and a one-third reduction in the likelihood of needing additional cancer therapies. This suggests that robotic-assisted radical prostatectomy may offer better cancer control with potentially lower downstream costs.