Research suggests that a balanced diet with mono- and polyunsaturated fats can improve cardiac function in patients with heart failure. By providing sufficient energy to the heart, a damaged heart can maintain its normal metabolic profile and utilize its preferred energy source.
Fusobacterium nucleatum, a common oral bacteria, facilitates disease and infection spreading from the mouth through the bloodstream. This bacterium is linked to increased risk of pregnancy complications, including miscarriage, preterm birth, and stillbirth.
A study by Lee A. Thompson and colleagues found that genetic influence was greater on reading than math, with shared environment influencing math more so than reading. The researchers analyzed the data from twins to determine the similarities in genetic and environmental influence between ADHD symptoms and academic ability.
Scientists at Case Western Reserve University, U.S., have created a polymer-based material that can heal itself when exposed to ultraviolet light. The new materials, called 'metallo-supramolecular polymers,' behave like normal polymers but can be repaired using light.
Researchers found that salt intake raises blood pressure by disrupting temperature regulation in the cardiovascular system, affecting some individuals more than others. This discovery may lead to a comprehensive theory explaining most cases of high blood pressure.
Researchers will study how tumor cells avoid immune detection, enabling cancer spread, and test whether modifying the environment can activate unresponsive immune cells against cancer. The grant enables visualization of tumor and immune cell interactions in real-time.
Researchers at Case Western Reserve University detected tiny amounts of Iodine 131 from Japan in Cleveland rainwater, with levels estimated as one-tenth that of natural background radiation. The isotope was found in rainwater collected on a campus roof and is being seen worldwide
Researchers found that most orthodontists prescribed removable retainers, with 58.2% opting for these over fixed lingual retainers. Patient compliance was generally high, with 60% wearing retainers more than 10 hours a day in the first three months.
Catalysts made of carbon nanotubes dipped in a polymer solution have been shown to equal the energy output and outperform platinum catalysts in fuel cells. The new process is simpler and cheaper, reducing the cost of fuel cells by up to 75%.
Researchers found that seedlings grow best with distant relatives in field soils but struggle with close relatives. This contradicts Darwin's idea that competition will be strongest between close relatives.
Researchers found that postmenopausal women on bisphosphonate therapies for osteoporosis had abnormal dental plaque levels, which could endanger the jawbone. The study recommends more frequent dental checkups, including deep periodontal cleanings, to control dental plaque and prevent bone loss.
Case Western Reserve University School of Medicine researchers have identified a new biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a degenerative brain disease with no cure. The biomarker, transferrin, shows promise in early diagnosis and potential therapy development.
The two-year project aims to improve the durability and lifetime of mirror-augmented photovoltaic systems. Researchers will test and qualify mirrors, PV modules, and MAPV systems to ensure reliable performance.
Researchers at Case Western Reserve University have developed a new chemotherapy method that targets cancer tumors more effectively by using gold nanoparticles to deliver an anti-cancer drug directly into the tumor. This approach allows for lower doses of toxic chemicals, reducing damage to healthy tissue.
Research from Case Western Reserve University shows that helping others in the AA program can lead to improved sobriety and reduced depression. The 'helper therapy principle' helps individuals with a similar condition, reducing egocentrism and selfishness.
Researchers at Case Western Reserve University School of Medicine will continue studying manic symptoms in children with a renewed $7.8 million NIMH grant. The study aims to develop accurate diagnoses and predictive factors for bipolar spectrum disorders in youth.
The Bipolar CHOICE trial will evaluate the real-world advantages and disadvantages of quetiapine compared to lithium for treating outpatients with bipolar disorder. The study aims to inform day-to-day practice in psychiatry with a focus on effectiveness, not just comparing treatments.
Researchers found a communication intervention effective in reducing ICU stays for chronic patients but less so for surgical and neurological cases. The study highlights the need for tailored approaches to support families making critical decisions for their loved ones.
A recent study by Case Western Reserve University reveals that misleading food labels can lead to excessive trans fat consumption and increased risk of deadly diseases. The FDA's current labeling protocol allows for 'zero grams' of trans fat, masking significant amounts that exceed recommended limits.
Researchers found that anger toward God often coincides with traumatic events, but can also arise from personal disappointments and interpersonal hurts. Overcoming this anger may require reflecting on one's situation and seeking reassurance from a higher power.
Researchers at Case Western Reserve University School of Medicine will study and develop new treatments for diseases of the retina, a leading cause of blindness. The $10.1 million grant aims to accelerate the development of effective therapies, particularly for age-related macular degeneration.
Researchers are working on four different projects: studying MTB infection, analyzing latent infection in humans, improving chemotherapy for glioblastoma multiforme, and exploring gene modification for stem cell selection. The funding will support a multidisciplinary team of experts in proteomics, genetic epidemiology, and cytokine bio...
Researchers at Case Western Reserve University have developed a novel capacitor design that could significantly increase energy density in power supplies for electric cars. The new technology uses titanium alloy and advanced materials to create a highly efficient and compact device capable of absorbing and providing surges of electricity.
Researchers have identified two FDA-approved cancer drugs that can inhibit NOD2's activity, offering a new avenue for treating Crohn's disease and sarcoidosis. The medications target the NOD2:RIP2 pathway, potentially alleviating symptoms and improving outcomes for patients with these conditions.
A study by Case Western Reserve University found that emergency department doctors are less likely to prescribe pain medication to patients with a history of crime, drug abuse, or poor health status. The researchers surveyed 398 physicians and analyzed the data to identify social biases in prescription practices.
Researchers at Case Western Reserve University have imaged atomic structural changes in sapphires that control their properties. These changes, called dislocations, involve small rearrangements of aluminum atoms and can affect the material's electrical, chemical, and magnetic properties as well as its strength and durability.
Researchers at Case Western Reserve University found that coaching styles can activate the brain's Positive Emotional Attractor, leading to increased cognitive functioning, openness, and better functioning. In contrast, critical or judgmental coaching methods can lead to the Negative Emotional Attractor, causing people to defend themse...
The seven-year project aims to reduce obesity and high blood pressure by increasing physical activity, healthy eating, sleep, and stress management in overweight and obese students. It will assess the effectiveness of three behavioral interventions within children's school and community environments.
A comprehensive review of 70 research articles finds that prescribed bed rest may have negative effects on pregnant women's physical and emotional health. The study suggests that hospital stays deny women the opportunity to rest in a comfortable environment, potentially leading to depression and post-traumatic shock disorder.
A study presented at the American Public Health Association's annual meeting found that excessive texting among teens is linked to poor health behaviors. Hyper-texting, defined as texting over 120 messages per day, was associated with a 40% higher risk of trying cigarettes and a 90% higher risk of having multiple sexual partners.
Researchers at Case Western Reserve University developed new software to analyze the three-dimensional movement of an insect's leg joints, allowing for a detailed understanding of cockroach locomotion. The software enables 90% accurate analysis of 106,496 individual points in hours, not weeks.
The researchers aim to understand how animals, including humans, quickly adjust to unexpected events. By studying the sea slug's ability to adjust its eating behavior, they hope to develop mathematical models that can predict how patterns of activity in the nervous system change over time.
A study led by Allison Webel aims to promote lifestyle changes among women with HIV, testing the effectiveness of a self-management intervention. The research targets sleep, exercise, personal time, and spirituality habits, aiming to empower individuals to take an active role in their treatment.
Researchers have developed electromechanical switches that can withstand twice the heat as transistors, enabling computers to operate in extreme temperatures. The switches, made from silicon carbide and nanotechnology, perform better than transistors at high temperatures and have no discernible leakage.
CWRU researcher Erin Lavik is developing synthetic platelets using nanotechnology to treat traumatic injuries. Her lab aims to fine-tune the artificial platelets and integrate them with drug delivery systems.
Case Western Reserve University researchers develop e-SMART-MH technology to improve patient-provider communications and manage mental health. The project aims to empower young adults to take control of their mental well-being, overcoming stigma and ensuring timely treatment.
Researchers at Case Western Reserve University have discovered the weakest link in tendons, a crucial connection between bones and muscles. The discovery focuses on collagen fibrils, which are five times stronger than tendons but may hold the key to increasing flexibility and healing damage.
A study by Case Western Reserve University found that stopping thoughts burns energy, similar to how thinking itself consumes energy. The researchers used a computer model and Metabolica software package to analyze brain metabolism.
Case Western Reserve researcher Menachem Shoham discovered new anti-pathogenic drugs that prevent MRSA's production of toxins, rendering the bacteria harmless. The drugs block the activation of a key bacterial protein, AgrA, preventing toxin release and serious infections.
A team from Case Western Reserve University has identified a novel dual recognition mechanism in Mycobacterium tuberculosis that may contribute to immune evasion. The discovery could aid in the design of new vaccines and antibiotics to combat the disease.
Researchers are developing an early warning system for bridge failures caused by scouring, using tiny fish-inspired sensors and radar technology. The system can provide real-time information on river bottom conditions and detect minute changes in depth and density of sediment.
A diagnostic test of eight short questions can detect depressive thinking patterns in women who care for an adult family member with a serious mental illness. The test has been found valid in different groups and cultures, and its successful completion can lead to prevention of serious depressive illness.
Researchers at Case Western Reserve University and Vanderbilt University used an infrared laser to pace an avian embryonic heart, showing no harm to the tissue. This non-invasive device may help understand environmental factors affecting heart rate in embryos and develop new pacemakers.
Researchers at Case Western Reserve University have discovered a new sporadic prion protein disease, Variably protease-sensitive prionopathy (VPSPr), which shares genotype characteristics with Creutzfeldt-Jakob disease. The abnormal prion protein in VPSPr exhibits distinct characteristics different from other prion diseases.
Dr. Nadeau's research focuses on the impact of ancestral generations on an individual's health status, challenging traditional studies that rely solely on inherited genes and environmental exposures. The NIH Director's Pioneer Award supports his five-year investigation into transgenerational genetic effects.
Researchers at Case Western Reserve University developed new techniques to identify drug resistance in malaria, enabling faster detection and saving lives. By using genetic assays and mathematical analysis, they can track drug immunity of the deadliest form of the disease in just days, far cheaper than traditional methods.
A team led by Dr. Jonathan Stamler will research the development of a new class of drugs that selectively dilate blood cells under hypoxia, enhancing soldiers' performance at high altitudes. The grant aims to improve tissue oxygenation and deliver more oxygen to tissues despite low blood oxygen content.
The Case Western Reserve University/University Hospitals Center for AIDS Research has received a five-year, $9 million NIH grant renewal to continue HIV-related research. The funding will support new initiatives on HIV and cancer links, faculty development, and international collaborations.
A three-year clinical study will examine the relationship between physical function decline and age-related disparities in breast cancer treatment. The study aims to develop a well-validated instrument for measuring functional decline among senior adults with cancer, ultimately improving breast cancer outcomes for older women.
A high-fat diet is found to activate nuclear factor kappa B (NF-κB) in the prostate, leading to inflammation, oxidative stress, and proliferation. The study provides direct evidence of a link between a high-fat diet and an increased risk of benign prostatic hyperplasia, prostatitis, and prostate cancer.