Researchers Katherine Jones-Smith and Harsh Mathur critique the work of physicist Richard Taylor, who claimed fractal analysis could authenticate Pollock's paintings. They found that fractal analysis leads to mathematical contradictions and inconsistencies in Pollock's works.
A new study from Case Western Reserve University explores the changing roles and emotions of caregivers in the early stages of dementia care. Family members reported experiencing frustration, resentment, grief, and loss of intimacy while taking on new responsibilities, yet also showing increased protectiveness towards loved ones.
A Case Western Reserve University study found that children's range of emotions in play can indicate how emotionally charged their memories will be. The researchers used this link to develop a tool for gauging emotional openness in children, which can help them process traumatic experiences and express negative emotions.
A new lunar meteorite, MIL 05035, has been discovered in Antarctica, providing a rare opportunity to study a part of the Moon's surface not visited by the US Apollo program. The meteorite exhibits unusual mineralogy and texture, offering clues about the Moon's formation and evolution.
The book commemorates Alois Alzheimer's discovery of Alzheimer's Disease (AD) and explores its evolution as a major public health problem, affecting 30-40 million people worldwide. The publication brings together key voices in the field to reflect on classic studies and chart the future direction of AD research.
Case Western Reserve University researchers found a dart-like molecule, Carboxyethylpyrroles (CEPs), that adheres to proteins in the eye, triggering uncontrolled blood vessel growth. This contributes to the development of age-related macular degeneration, the leading cause of blindness over 65.
Researchers like Barkley aim to understand the basic science of HIV-1 function and develop new therapies. The recent NIH grant supports a new area of AIDS research focusing on the chemical processes between the two pieces of reverse transcriptase protein that mobilize the HIV-1 virus.
Researchers at Case Western Reserve University developed a method to bypass spinal cord injuries by regenerating severed nerve fibers and reconnecting them with the spinal cord. The treatment, using an enzyme called chondroitinase, resulted in improved mobility in rats with impaired motor functions.
A new species of hoofed mammal, Hemihegetotherium trilobus, has been discovered in Bolivia with distinctive three-lobed lower molar teeth. The animal is believed to have lived around 13 million years ago and was part of the notoungulate group, which dominated South America before its extinction.
Case Western Reserve University has been awarded a prestigious multimillion-dollar research center by the National Science Foundation, focusing on polymers research. The CLiPS center aims to lead the nation with an integrated program of research and education through its unique microlayering and nanolayering process.
Researchers at Case Western Reserve University have found a protein associated with brain cell death in Alzheimer's disease. The study suggests that the multi-domain protein Vav plays a critical role in triggering a cascade of reactions leading to oxidative damage and neural cell death, a key characteristic of Alzheimer's.
The Ohio Tobacco Use Prevention and Control Foundation has established a case-based research and evaluation center at Case Western Reserve University. The Center will work with over 60 community organizations across the state to provide prevention and cessation programming, as well as analyze trends in tobacco surveillance data.
Long-term cancer survivors experience ongoing concerns about cancer recurrence and treatment side effects, affecting their mental health. Research found that these worries are linked to depression and anxiety, with varying levels of concern across different types of cancer.
The center will support development of new therapies for heart, cancer, and neurological disorders through early patient clinical trials. Non-embryonic stem cell research has been exceptionally strong in Ohio, bringing together academic investigators and industry partners to accelerate moving cutting-edge research into the clinic.
Reddy's study found a selective loss of both presynaptic and postsynaptic proteins in AD patients' brains, highlighting the need for further investigation into synaptic damage. The award recognizes his work on understanding molecular and cellular bases of neurodegenerative diseases.
Researchers investigated whether older adults' lower IQ scores are due to aging or sensory deficits. The study found that even subtle perception deficits, such as reduced spatial contrast sensitivity, can significantly impact performance on intelligence tests.
A team of law professors, physicians, and bioethicists will develop standards for tests on human subjects in research involving genetic technologies for enhancement. The project aims to identify differences between therapeutic and non-therapeutic enhancements and determine ethical conditions for conducting such research.
The landmark book celebrates the centennial of Alzheimer's discovery, narrating its evolution from a major cause of late-life dementia. The publication brings to life classic studies defining the disease research, featuring contributions from prominent researchers.
Researchers discovered a link between oral bacteria and preterm birth, finding Bergeyella bacteria in the amniotic fluid of pregnant women. This pilot study suggests that oral bacteria may play a role in premature deliveries, which can lead to health challenges for babies and increased medical costs.
Researchers at Case Western Reserve University have identified a new cell type called Blanes cells that play a critical role in shaping the output of the olfactory system. These cells selectively communicate with granule cells, leading to a disproportionate impact on the olfactory system's functioning.
A recent study by Case Western Reserve University found that private practice dentists and hygienists primarily counsel middle-class patients with higher education on preventing dental diseases. Despite the lack of peer feedback, most dentists use comfort-giving strategies to make patients feel at ease during visits.
A Case School of Engineering professor is using virtual reality to train brain and heart surgeons, reducing learning time and allowing independent practice. He aims to expand minimally invasive techniques to complex surgeries, virtually eliminating the need for heart/lung machines.
A new communication system is being tested at Cleveland-area hospitals to address family decision-making with critically ill patients. The system aims to provide families comfort and support while reducing costs and length of stay in ICUs.
The Case Western Reserve University PhD program has received a $850,000 grant from the Howard Hughes Medical Institute to develop a novel curriculum and administration of the program. The program aims to prepare students for translational research and clinical applications.
Case scientists demonstrate that motor neurons' behavioral roles change depending on body positioning, with implications for developing robots and prosthetic devices. Their research provides the first demonstration of Bernstein's hypothesis in a behaving animal.
A new study has found that high blood pressure and kidney disease increase the risk for heart disease and stroke in older Americans. Patients with moderate chronic kidney disease had a 38% greater chance of developing heart disease than those with normal kidney function.
Researchers found that people tend to use apologies and concessions in intimate relationships, while excuses are less effective. The study also revealed that the context of the situation influences the chosen strategy, with serious offenses generating additional apologies and concessions.
Case Western Reserve University professor Eric Pearlman has received a prestigious vision research grant to study the immunology of the eye. The grant will help researchers understand the immunological basis of diseases such as age-related macular degeneration and diabetic retinopathy.
The Case Department of Ophthalmology at Case Western Reserve University has been awarded a $110,000 grant by the Research to Prevent Blindness (RPB) organization. The grant will support research into blinding eye diseases.
Case researchers Ramani Pilla, Catherine Loader, and Cyrus Taylor discover a method to find needles in haystacks using geometric approaches. They test their technique with computer simulations, demonstrating its ability to significantly increase detection probabilities.
Researchers found that risedronate therapy significantly reduced plaque and improved periodontal status in postmenopausal women with osteoporosis. The study also highlighted the link between osteoporosis and periodontal disease, suggesting similar treatment and management may minimize tooth loss.
A Phase I study will test the safety of injecting bone marrow stem cells into coronary arteries of patients with chronic ischemic coronary artery disease. The trial aims to determine if this method can help patients with this heart condition in the future.
New treatments for Leber congenital amaurosis have been developed in mice, providing effective means of restoring retinal function. The treatments combine gene therapy and oral administration of vitamin A-like compounds, showing promise for treating this blindness-causing eye disease.
A study by Case Western Reserve University researchers found that apigenin, a plant flavonoid, slowed tumor growth in mice with prostate cancer. Apigenin also reduced IGF-1 levels associated with increased cancer risk and triggered cell self-destruction.
A joint project between Cyberkinetics, Case Western Reserve University, and the Cleveland FES Center aims to develop a neuroprosthetic system capable of restoring partial arm and hand function. The proposed system combines limb movement technology with brain-interface technology to enable human users to control devices through thought ...
Case Western Reserve University astronomers have captured a deep, wide-field image of the Virgo Cluster, revealing a complex web of intracluster starlight. The faint starlight is made up of stars ripped out of galaxies as they collide, providing an 'archaeological record' of violent cluster galaxy lives.
A study found that an abstinence-only sex education program increased teens' knowledge of HIV/STDs and their commitment to abstinence. However, it had mixed effects on sexual behavior, with no impact on the likelihood of having sex or using condoms. The program may reduce casual sex encounters among sexually active students.
Researchers found that pomegranate fruit extracts inhibit the overproduction of MMP enzymes in human cartilage cells, slowing cartilage degradation in osteoarthritis. The findings suggest a potential therapeutic effect for consuming pomegranate fruit extract to protect cartilage.
Researchers found that exercising regularly, eating a high-quality diet and maintaining a normal weight can reduce the risk of periodontitis by up to 40%. These healthy behaviors also contribute to lowering diabetes risk factors. Regular monitoring and promotion of these habits by oral health professionals can help prevent gum disease.
Researchers have identified a gene marker called vimentin that detects colon cancer with 46% accuracy using DNA stool tests. The marker has potential to be used in combination with other DNA markers to detect 100% of colon cancers.
Researchers at Case Western Reserve University found that taking ibuprofen before gum surgery can lead to nearly double the amount of blood loss compared to those who don't take the medication. The study suggests patients should avoid NSAIDs before oral surgeries to minimize bleeding risk.
Researchers Hideo Hara and Takeshi Tabira develop an effective oral vaccine treatment for Alzheimer's disease using AAV vector carrying Aß cDNA, which reduces side effects associated with traditional immunotherapy. The treatment has shown promising results in mice, indicating a potential therapeutic approach for the disease.
A new study found that higher adolescent IQ and greater activity levels are associated with a lower risk of dementia and mild cognitive impairments. The research used historical data from high school records and interviews with graduates to explore the relationship between early-life factors and late-life cognitive status.
A recent survey found that 88% of nursing homes have a staff dentist, but most patients receive off-site dental care due to limited on-site equipment. Daily oral care is often assigned to nursing assistants, who are expected to prioritize other tasks.
Scientists have successfully delivered genes to the lungs of CF mice using DNA nanoparticles, enabling real-time imaging and assessment of gene expression. This breakthrough technology holds promise for treating serious lung diseases like cystic fibrosis with novel nucleic acid-based therapies.
Scientists have discovered a key genetic mutation that causes a dramatic increase in testicular cancer incidence in mice, suggesting new avenues for understanding the disease's genetic control. The mutation affects RNA editing, which may be used to diagnose at-risk individuals or develop targeted therapeutics.
Ralph Horwitz, M.D., is receiving the Glaser Award from the Society of General Internal Medicine (SGIM) in recognition of his significant contributions to research and education in general internal medicine. The award is supported by grants from the Henry J. Kaiser Family Foundation and the Commonwealth Fund.
The grant aims to develop smart nanoparticles that can deliver photoactivated molecules to kill tumors while sparing healthy tissue. These nanoparticles will also deliver corrective genes to treat genetic disorders and inhibit viral infections or cancers. The project targets diseases like hemophilia, cancer, and viral infections.
Arteriocyte, a startup company spun out from Case Western Reserve University, is developing a novel stem cell therapy to generate new blood vessels and replace damaged ones in patients with heart disease. The therapy has shown encouraging results in animal studies and plans for patient testing are pending NIH and FDA approval.
A team of researchers from Case Western Reserve University propose an alternate view on the pathology of Alzheimer's disease (AD), suggesting that neurofibrillary tangles (NFTs) may be protective against oxidative stress. NFT-bearing neurons can survive for decades, and their presence may be a response to reduce oxidative damage.