Researchers have identified a shared neural mechanism for building confidence across multiple senses, including vision, audition, and touch. The study's findings support the supramodality hypothesis, suggesting that confidence estimates share a common format in the brain.
Researchers found that katabatic winds in Antarctica cause sublimation of snowflakes, reducing precipitation and affecting the ice sheet's mass balance. This phenomenon could be worsened by climate change.
Researchers at EPFL and University of Cambridge create device harnessing microscopic drum motion to convert signals between two circuits. The system enables dynamic reconfiguration of the isolator's direction, promising a new platform for building microwave devices without magnetic fields.
EPFL scientists have discovered metabolic differences between hepatoblastoma subtypes and identified biomarkers to aid in more accurate subtyping. The study reveals that embryonal hepatoblastoma cells use glucose and are sensitive to its metabolism, offering a new approach for personalized treatment.
A study found that vessel growth created by tumors can enhance immunotherapy effects against melanoma. The growth secreted chemokines that attracted T cells into the tumor environment, leading to long-lasting anti-tumor immunity.
EPFL researchers have developed a scanning transmission electron microscopy (STEM) method to generate fast and reliable 3D images of complex curvilinear structures. This tilt-less 3D electron imaging technique can acquire images in a single shot, opening up new avenues for real-time 3D imaging of dynamic material and biological processes.
Researchers have discovered that STING triggers pro-apoptotic responses in T cells, which may lead to new treatments for T-cell lymphomas. The study also found that delivering a small molecule that activates the STING pathway can prevent the growth of T cell-derived tumors in live animals.
Researchers at EPFL discovered key molecules driving lymphangiogenesis in response to worm infections, revealing a complex cross-talk between B cells and fibroblastic reticular cells.
Researchers at EPFL studied the TADs involved in digit development, finding that they can host multiple associations between genes and enhancers. Disrupting the 3D structure of chromatin leads to remodeling of TADs, with CTCF mediating long-range DNA contacts.
Researchers at EPFL have developed a substrate-specific method to detect electron transfer in photovoltaic devices. The new approach uses deep-ultraviolet continuum pulses to probe the excitonic transitions of transition-metal oxide substrates, providing a route to studying solid-state-sensitized solar cells.
Researchers discovered that innate immune system's DNA-sensing mechanism controls cellular senescence, promoting the secretion of inflammation-mediating proteins. This process plays a role in various contexts of senescence, including oxidative stress, oncogene signaling, and irradiation.
A study by EPFL scientists found that schizophrenia patients do not have a disturbed sense of body ownership. The study used the Full-Body Illusion test and showed that patients performed similarly to healthy controls, indicating that their sense of body ownership is unaffected by the disorder.
The Envirobot robot uses chemical, physical and biological sensors to map variations in water conductivity and temperature, detecting heavy metals like mercury. Biological sensors comprising bacteria, crustaceans and fish cells indicate water toxicity.
Researchers at EPFL's Laboratory for Fundamental BioPhotonics have developed a microscope that can track three-dimensional spatial changes in molecular structure and chemistry of confined systems. The study reveals a remarkable spread in surface reactivity, even on small portions of a capillary, shedding light on the chemical reactivit...
Researchers at EPFL have developed a uranium-based compound that enables nitrogen fixation to occur in ambient conditions, paving the way for more efficient catalysts and new concepts for metals beyond uranium. This breakthrough has significant implications for the production of ammonia and other nitrogen-containing compounds.
A clinical study showed that patients wearing a smart walking assist immediately improved their locomotor abilities and could perform daily activities without support. The algorithm tailors assistance to each patient based on leg movement, stride length, and muscle activity to promote natural walking patterns.
Researchers found that low-dose diazepam increased social competitiveness in high- and medium-anxious rats by boosting dopamine release and mitochondrial function. The study suggests that this mechanism could be targeted through non-pharmacological interventions.
Scientists at EPFL have developed a new ligand that can extend the half-life of peptide drugs from minutes to several days. The ligand, which is easy to synthesize and has high affinity for human albumin, can be appended to peptides using standard synthesizing techniques.
Researchers have experimentally observed a new quantum many body state in the Shastry-Sutherland model, where atomic magnets are quantum-entangled in sets of four. This discovery has implications for materials science and quantum information technology, and could lead to the development of new theoretical methods.
Researchers found that social rank triggers differential vulnerability to chronic stress and identifies brain energy metabolism as a predictive biomarker. The study showed that dominant mice display susceptibility to stress through social avoidance, while subordinate mice exhibit resilience.
Researchers discovered that the Sestrin1 gene is frequently missing or malfunctioning in follicular lymphoma patients, leading to tumor growth and poor prognosis. The study found that targeting this gene can suppress tumors and improve treatment efficacy, offering hope for new therapies.
Researchers have found that some pathogenic bacteria use an undulating 'wave-pattern' to mark future sites of division, instead of conventional biological systems. This discovery provides new insights into how these bacteria divide and could lead to new ways to fight them.
Researchers at EPFL challenge fundamental law of physics and discover asymmetric resonant and wave-guiding systems capable of storing large amounts of energy over prolonged periods while maintaining broad bandwidths. The breakthrough has implications for telecommunications, optical detection systems, and broadband energy harvesting.
Researchers identified that the CMG2 protein binds and controls collagen VI levels, leading to its accumulation in tissues causing painful deformities. The study provides new insights into the physiological function of CMG2 and demonstrates its interaction with collagen VI.
A team of researchers from KIT and EPFL used optical silicon nitride micro-resonators to generate continuously circulating solitons, enabling massive parallel data transmission on 179 wavelength channels. The system achieved a record-breaking data rate of over 50 terabits per second.
Researchers at EPFL developed a dynamic test method that replicates blood and lymphatic systems, allowing for more accurate nanoparticle testing. This method reduces discrepancies between in vitro and in vivo tests, providing valuable insights into nanoparticle behavior.
EPFL scientists have developed an Earth-abundant catalyst to split carbon dioxide into oxygen and carbon monoxide, producing liquid fuels from renewable sources. The catalyst achieved a high efficiency of 13.4% in converting CO2 to CO using solar energy.
Scientists have developed an ultra-stable perovskite solar cell with a constant efficiency of 11.2% for more than 10,000 hours, resolving stability issues and paving the way for commercialization. The 2D/3D hybrid perovskite design efficiently absorbs light across the visible spectrum and transports electrical charges.
Scientists have observed a surprising order in the surface of water droplets at the nanoscale, with molecules behaving like those in ice. This discovery could lead to a better understanding of atmospheric, biological, and geological processes, as researchers explore how additives like salt affect the water network.
EPFL scientists have developed a mathematical method using persistent homology to quantify similarity of pore structures in nanoporous materials. This allows searching databases for similar pore shapes and discovering new materials with optimal performance.
Graphene-based quantum capacitor offers advantages in fabrication and resistance to electromagnetic interference. The device has the potential to produce stable qubits and can be used for high-frequency circuits or other electro-optic applications.
Scientists at EPFL developed an antibody-linked biosensor that can track drug concentration in the blood by changing color, enabling patients to monitor their treatment levels at home. The biosensor can be adapted to detect virtually unlimited number of molecules.
Scientists at EPFL develop a microwave resonator coupled to a metallic micro-drum, creating a quantum reservoir that can shape the states of microwaves. The findings enable novel phenomena in cavity optomechanical systems.
Intento's device enables stroke patients to self-administer electrical stimulation, improving mobility and performing basic tasks. 70% of patients showed significant improvement in motor functions compared to conventional therapy.
Researchers find that members of the DUX family of proteins, specifically DUX4, trigger gene expression program in human embryos. DUX4 stimulates expression of genes induced during zygotic genome activation by binding to their regulatory regions.
Researchers developed a novel fabrication method combining 3D printing and electroplating to produce complex metallic structures for molecular beam-splitting. This approach enables the creation of high-voltage electrodes with impeccable surface properties and precision alignment, overcoming previous fabrication problems.
EPFL scientists have found that light plays a crucial role in controlling the morphology of perovskite crystals, leading to improved photovoltaic performance. The study reveals that the presence of light accelerates the formation of perovskites and enhances crystal growth.
Researchers have shed light on the absorption of light by anatase titanium dioxide using cutting-edge spectroscopic techniques and theoretical calculations. They discovered that strongly bound excitons exhibit novel properties, including confinement to a two-dimensional plane and stability at room temperature.
Researchers reprogram tumor blood vessels to block tumor growth and facilitate T cell arrival, improving cancer immunotherapy efficacy. A2V therapy inhibits metastasis and promotes anti-tumor immunity, which can be enhanced by PD-1 checkpoint blockade.
Researchers at EPFL's Environmental Remote Sensing Laboratory developed an algorithm to classify six different classes of snowflakes, improving precipitation measurement and forecast accuracy. The study used high-resolution images of snowflakes taken from three angles and analyzed their shape, geometry, and electromagnetic properties.
Scientists have discovered a synergistic effect between an anticancer and an antirheumatic drug, improving the former's ability to kill off cancer cells. The combination works by interacting with the cell's DNA, disrupting normal function and causing cell death.
Researchers at EPFL develop synthetic methods to introduce chemical modifications on huntingtin, reducing its toxicity and aggregation. The study reveals key findings on the relationship between post-translational modifications and huntingtin structure, function, and toxicity.
Researchers developed a comprehensive mathematical model of the deadliest malaria parasite Plasmodium falciparum metabolism. The model accurately integrates genetics and metabolism data, predicting which genes are indispensable for every biological function in the parasite.
Scientists at Ecole Polytechnique Fédérale de Lausanne are developing intelligent neuroprosthetics that can decode brain signals and stimulate spinal cord muscles to facilitate walking movements. Clinical trials are currently underway to test the feasibility of these devices on patients with partial paralysis.
A family of ~350 human proteins has been found to establish complex interplay with transposable elements, creating largely human-specific gene regulatory networks. These networks influence all of human biology, both in health and disease, and are likely to have profound implications for understanding human development and physiology.
EPFL scientists developed a new computer model to predict allosteric pathways for enzymes and other proteins, enabling more efficient drug design. The model proposes a new hypothesis for allosteric architectures, introducing the concept of 'levers' that amplify responses at a distance.
Researchers found a faster way for six-legged robots to move on flat ground without adhesive pads, dubbed the 'bipod' gait. This locomotor strategy is more efficient than traditional tripod gait used by insects.
Researchers at EPFL have determined a delay of one billionth of one billionth of a second in photoemission by measuring the spin of photoemitted electrons. This discovery has significant implications for understanding the properties of electrons in solids and advancing spectroscopy techniques.
The H0LiCOW collaboration has made a new measurement of the Hubble constant using quasars and gravitational lensing. The result agrees with recent independent studies but disagrees significantly with cosmic microwave background measurements, potentially indicating new physics beyond the standard cosmological model.
Researchers at EPFL developed a simple technique for drawing nanometric patterns on hollow polymer fibers, overcoming previous limitations. The new method can create highly complex designs with feature sizes two orders of magnitude smaller than before, paving the way for various applications in biology, materials science, and beyond.